-
1
-
-
33645376448
-
Immunopathogenesis and immunotherapy of multiple sclerosis
-
Hemmer, B., Nessler, S., Zhou, D., Kieseier, B. and Hartung, H. P. (2006) Immunopathogenesis and immunotherapy of multiple sclerosis. Nat. Clin. Pract. Neurol. 2, 201-211
-
(2006)
Nat. Clin. Pract. Neurol.
, vol.2
, pp. 201-211
-
-
Hemmer, B.1
Nessler, S.2
Zhou, D.3
Kieseier, B.4
Hartung, H.P.5
-
2
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama, Y., Nakae, S., Matsuki, T., Nambu, A., Ishigame, H., Kakuta, S., Sudo, K. and Iwakura, Y. (2006) IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J. Immunol. 177, 566-573
-
(2006)
J. Immunol.
, vol.177
, pp. 566-573
-
-
Komiyama, Y.1
Nakae, S.2
Matsuki, T.3
Nambu, A.4
Ishigame, H.5
Kakuta, S.6
Sudo, K.7
Iwakura, Y.8
-
3
-
-
34548133584
-
Multiple sclerosis: a complicated picture of autoimmunity
-
McFarland, H. F. and Martin, R. (2007) Multiple sclerosis: a complicated picture of autoimmunity. Nat. Immunol. 8, 913-919
-
(2007)
Nat. Immunol.
, vol.8
, pp. 913-919
-
-
McFarland, H.F.1
Martin, R.2
-
4
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y. H., Wang, Y., Hood, L., Zhu, Z., Tian, Q. and Dong, C. (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6, 1133-1141
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
5
-
-
0027973242
-
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains
-
Bo, L., Dawson, T. M., Wesselingh, S., Mork, S., Choi, S., Kong, P. A., Hanley, D. and Trapp, B. D. (1994) Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann. Neurol. 36, 778-786
-
(1994)
Ann. Neurol.
, vol.36
, pp. 778-786
-
-
Bo, L.1
Dawson, T.M.2
Wesselingh, S.3
Mork, S.4
Choi, S.5
Kong, P.A.6
Hanley, D.7
Trapp, B.D.8
-
6
-
-
0032414199
-
Reactive oxygen species are required for the phagocytosis of myelin by macrophages
-
van der Goes, A., Brouwer, J., Hoekstra, K., Roos, D., van den Berg, T. K. and Dijkstra, C. D. (1998) Reactive oxygen species are required for the phagocytosis of myelin by macrophages. J. Neuroimmunol. 92, 67-75
-
(1998)
J. Neuroimmunol.
, vol.92
, pp. 67-75
-
-
van der Goes, A.1
Brouwer, J.2
Hoekstra, K.3
Roos, D.4
van den Berg, T.K.5
Dijkstra, C.D.6
-
7
-
-
36448981390
-
Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology
-
Schreibelt, G., van Horssen, J., van Rossum, S., Dijkstra, C. D., Drukarch, B. and de Vries, H. E. (2007) Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology. Brain Res. Rev. 56, 322-330
-
(2007)
Brain Res. Rev.
, vol.56
, pp. 322-330
-
-
Schreibelt, G.1
van Horssen, J.2
van Rossum, S.3
Dijkstra, C.D.4
Drukarch, B.5
de Vries, H.E.6
-
8
-
-
0037491616
-
Caspasemediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination
-
Hisahara, S., Okano, H. and Miura, M. (2003) Caspasemediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination. Neurosci. Res. 46, 387-397
-
(2003)
Neurosci. Res.
, vol.46
, pp. 387-397
-
-
Hisahara, S.1
Okano, H.2
Miura, M.3
-
10
-
-
0242661909
-
a-Lipoic acid and cardiovascular disease
-
Wollin, S. D. and Jones, P. J. (2003) a-Lipoic acid and cardiovascular disease. J. Nutr. 133, 3327-3330
-
(2003)
J. Nutr.
, vol.133
, pp. 3327-3330
-
-
Wollin, S.D.1
Jones, P.J.2
-
11
-
-
33745833194
-
A-Lipoic acid is a weak dual PPARa/γ agonist: an ester derivative with increased PPARa/γ efficacy and antioxidant activity
-
Harrihar, P., Christopher, H., Jaya, R., Candy, L., Amar, C., Renu, D., Theodore, K., Jefferson, C., Mitchell, A. and Stephen, B. (2005) A-Lipoic acid is a weak dual PPARa/γ agonist: an ester derivative with increased PPARa/γ efficacy and antioxidant activity. J. Appl. Res. 555, 510-523
-
(2005)
J. Appl. Res.
, vol.5
, pp. 510-523
-
-
Harrihar, P.1
Christopher, H.2
Jaya, R.3
Candy, L.4
Amar, C.5
Renu, D.6
Theodore, K.7
Jefferson, C.8
Mitchell, A.9
Stephen, B.10
-
12
-
-
70350459594
-
The nuclear receptor PPAR γ selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity
-
Klotz, L., Burgdorf, S., Dani, I., Saijo, K., Flossdorf, J, Hucke, S., Alferink, J., Nowak, N., Beyer, M., Mayer, G. et al. (2009) The nuclear receptor PPAR γ selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J. Exp. Med. 206, 2079-2089
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2079-2089
-
-
Klotz, L.1
Burgdorf, S.2
Dani, I.3
Saijo, K.4
Flossdorf, J.5
Hucke, S.6
Alferink, J.7
Nowak, N.8
Beyer, M.9
Mayer, G.10
-
13
-
-
33847403883
-
Peroxisomeproliferator- activated receptor γ is required for regulatory CD4+ T cell-mediated protection against colitis
-
Hontecillas, R. and Bassaganya-Riera, J. (2007) Peroxisomeproliferator- activated receptor γ is required for regulatory CD4+ T cell-mediated protection against colitis. J. Immunol. 178, 2940-2949
-
(2007)
J. Immunol.
, vol.178
, pp. 2940-2949
-
-
Hontecillas, R.1
Bassaganya-Riera, J.2
-
14
-
-
70450223896
-
Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells
-
Chen, S. J., Wang, Y. L., Kao, J. H., Wu, S. F., Lo, W. T., Wu, C. C., Tao, P. L., Wang, C. C., Chang, D. M. and Sytwu, H. K. (2009) Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells. Mol. Immunol. 47, 567-574
-
(2009)
Mol. Immunol.
, vol.47
, pp. 567-574
-
-
Chen, S.J.1
Wang, Y.L.2
Kao, J.H.3
Wu, S.F.4
Lo, W.T.5
Wu, C.C.6
Tao, P.L.7
Wang, C.C.8
Chang, D.M.9
Sytwu, H.K.10
-
15
-
-
0033824989
-
Transgenic mice expressing surface markers for IFN-γ and IL-4 producing cells
-
Hsieh, S., Chen, N., Tarbell, K., Liao, N., Lai, Y., Lee, K., Wu, S., Sytwu, H., Han, S. and McDevitt, H. (2000) Transgenic mice expressing surface markers for IFN-γ and IL-4 producing cells. Mol. Immunol. 37, 281-293
-
(2000)
Mol. Immunol.
, vol.37
, pp. 281-293
-
-
Hsieh, S.1
Chen, N.2
Tarbell, K.3
Liao, N.4
Lai, Y.5
Lee, K.6
Wu, S.7
Sytwu, H.8
Han, S.9
McDevitt, H.10
-
16
-
-
0036790853
-
a-Lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis
-
Marracci, G. H., Jones, R. E., McKeon, G. P. and Bourdette, D. N. (2002) a-Lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis. J. Neuroimmunol. 131, 104-114
-
(2002)
J. Neuroimmunol.
, vol.131
, pp. 104-114
-
-
Marracci, G.H.1
Jones, R.E.2
McKeon, G.P.3
Bourdette, D.N.4
-
17
-
-
10744226446
-
a-Lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis
-
Morini, M., Roccatagliata, L., Dell'Eva, R., Pedemonte, E., Furlan, R., Minghelli, S., Giunti, D., Pfeffer, U., Marchese, M., Noonan, D. et al. (2004) a-Lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 148, 146-153
-
(2004)
J. Neuroimmunol.
, vol.148
, pp. 146-153
-
-
Morini, M.1
Roccatagliata, L.2
Dell'Eva, R.3
Pedemonte, E.4
Furlan, R.5
Minghelli, S.6
Giunti, D.7
Pfeffer, U.8
Marchese, M.9
Noonan, D.10
-
18
-
-
33646050051
-
IL-4-induced peroxisome-proliferator-activated receptor gamma activation inhibits NF-γB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases
-
Paintlia, A. S., Paintlia, M. K., Singh, I. and Singh, A. K. (2006) IL-4-induced peroxisome-proliferator-activated receptor gamma activation inhibits NF-γB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases. J. Immunol. 176, 4385-4398
-
(2006)
J. Immunol.
, vol.176
, pp. 4385-4398
-
-
Paintlia, A.S.1
Paintlia, M.K.2
Singh, I.3
Singh, A.K.4
-
19
-
-
0035341427
-
Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome-proliferator-activated receptor-γ
-
Niino, M., Iwabuchi, K., Kikuchi, S., Ato, M., Morohashi, T., Ogata, A., Tashiro, K. and Onoe, K. (2001) Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome-proliferator-activated receptor-γ . J. Neuroimmunol. 116, 40-48
-
(2001)
J. Neuroimmunol.
, vol.116
, pp. 40-48
-
-
Niino, M.1
Iwabuchi, K.2
Kikuchi, S.3
Ato, M.4
Morohashi, T.5
Ogata, A.6
Tashiro, K.7
Onoe, K.8
-
20
-
-
73449102477
-
Modeling multiple sclerosis in laboratory animals
-
Schreiner, B., Heppner, F. L. and Becher, B. (2009) Modeling multiple sclerosis in laboratory animals. Semin. Immunopathol. 31, 479-495
-
(2009)
Semin. Immunopathol.
, vol.31
, pp. 479-495
-
-
Schreiner, B.1
Heppner, F.L.2
Becher, B.3
-
21
-
-
0041976916
-
a-Lipoic acid decreases thiol reactivity of the insulin receptor and protein tyrosine phosphatase 1B in 3T3-L1 adipocytes
-
Cho, K. J., Moini, H., Shon, H. K., Chung, A. S. and Packer, L. (2003) a-Lipoic acid decreases thiol reactivity of the insulin receptor and protein tyrosine phosphatase 1B in 3T3-L1 adipocytes. Biochem. Pharmacol. 66, 849-858
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 849-858
-
-
Cho, K.J.1
Moini, H.2
Shon, H.K.3
Chung, A.S.4
Packer, L.5
-
22
-
-
0034773628
-
Molecular aspects of lipoic acid in the prevention of diabetes complications
-
Packer, L., Kraemer, K. and Rimbach, G. (2001) Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition 17, 888-895
-
(2001)
Nutrition
, vol.17
, pp. 888-895
-
-
Packer, L.1
Kraemer, K.2
Rimbach, G.3
-
23
-
-
33645376729
-
Modulation of cardiac and aortic peroxisome-proliferatoractivated receptor-γ expression by oxidative stress in chronically glucose-fed rats
-
El Midaoui, A., Wu, L., Wang, R. and de Champlain, J. (2006) Modulation of cardiac and aortic peroxisome-proliferatoractivated receptor-γ expression by oxidative stress in chronically glucose-fed rats. Am. J. Hypertens. 19, 407-412
-
(2006)
Am. J. Hypertens.
, vol.19
, pp. 407-412
-
-
El Midaoui, A.1
Wu, L.2
Wang, R.3
de Champlain, J.4
-
24
-
-
0036182681
-
Prevention of hypertension, insulin resistance, and oxidative stress by a-lipoic acid
-
El Midaoui, A. and de Champlain, J. (2002) Prevention of hypertension, insulin resistance, and oxidative stress by a-lipoic acid. Hypertension 39, 303-307
-
(2002)
Hypertension
, vol.39
, pp. 303-307
-
-
El Midaoui, A.1
de Champlain, J.2
-
25
-
-
0033080764
-
a-Lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve
-
Mitsui, Y., Schmelzer, J. D., Zollman, P. J., Mitsui, M., Tritschler, H. J. and Low, P. A. (1999) a-Lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve. J. Neurol. Sci. 163, 11-16
-
(1999)
J. Neurol. Sci.
, vol.163
, pp. 11-16
-
-
Mitsui, Y.1
Schmelzer, J.D.2
Zollman, P.J.3
Mitsui, M.4
Tritschler, H.J.5
Low, P.A.6
-
26
-
-
0032788081
-
Treatment of symptomatic diabetic polyneuropathy with the antioxidant a-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study).ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy
-
Ziegler, D., Hanefeld, M., Ruhnau, K. J., Hasche, H., Lobisch, M., Schutte, K., Kerum, G. and Malessa, R. (1999) Treatment of symptomatic diabetic polyneuropathy with the antioxidant a-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy. Diabetes Care 22, 1296-1301
-
(1999)
Diabetes Care
, vol.22
, pp. 1296-1301
-
-
Ziegler, D.1
Hanefeld, M.2
Ruhnau, K.J.3
Hasche, H.4
Lobisch, M.5
Schutte, K.6
Kerum, G.7
Malessa, R.8
-
27
-
-
33845499323
-
Oral treatment with a-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial
-
Ziegler, D., Ametov, A., Barinov, A., Dyck, P. J., Gurieva, I., Low, P. A., Munzel, U., Yakhno, N., Raz, I., Novosadova, M. et al. (2006) Oral treatment with a-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care 29, 2365-2370
-
(2006)
Diabetes Care
, vol.29
, pp. 2365-2370
-
-
Ziegler, D.1
Ametov, A.2
Barinov, A.3
Dyck, P.J.4
Gurieva, I.5
Low, P.A.6
Munzel, U.7
Yakhno, N.8
Raz, I.9
Novosadova, M.10
-
28
-
-
1242337352
-
Treatment of symptomatic diabetic polyneuropathy with the antioxidant a-lipoic acid: a meta-analysis
-
Ziegler, D., Nowak, H., Kempler, P., Vargha, P. and Low, P. A. (2004) Treatment of symptomatic diabetic polyneuropathy with the antioxidant a-lipoic acid: a meta-analysis. Diabetic Med. 21, 114-121
-
(2004)
Diabetic Med.
, vol.21
, pp. 114-121
-
-
Ziegler, D.1
Nowak, H.2
Kempler, P.3
Vargha, P.4
Low, P.A.5
-
29
-
-
38449099641
-
a-Lipoic acid as a new treatment option for Alzheimer's disease - a 48 months follow-up analysis
-
Hager, K., Kenklies, M., McAfoose, J., Engel, J. and Munch, G. (2007) a-Lipoic acid as a new treatment option for Alzheimer's disease - a 48 months follow-up analysis. J. Neural Transm. Suppl. 189-193
-
(2007)
J. Neural Transm. Suppl.
, pp. 189-193
-
-
Hager, K.1
Kenklies, M.2
McAfoose, J.3
Engel, J.4
Munch, G.5
-
30
-
-
51649101069
-
Examining the evidence: complementary adjunctive therapies for multiple sclerosis
-
Namaka, M., Crook, A., Doupe, A., Kler, K., Vasconcelos, M., Klowak, M., Gong, Y., Wojewnik-Smith, A. and Melanson, M. (2008) Examining the evidence: complementary adjunctive therapies for multiple sclerosis. Neurol. Res. 30, 710-719
-
(2008)
Neurol. Res.
, vol.30
, pp. 710-719
-
-
Namaka, M.1
Crook, A.2
Doupe, A.3
Kler, K.4
Vasconcelos, M.5
Klowak, M.6
Gong, Y.7
Wojewnik-Smith, A.8
Melanson, M.9
-
31
-
-
15544390831
-
Lipoic acid in multiple sclerosis: a pilot study
-
Yadav, V., Marracci, G., Lovera, J., Woodward, W., Bogardus, K., Marquardt, W., Shinto, L., Morris, C. and Bourdette, D. (2005) Lipoic acid in multiple sclerosis: a pilot study. Mult. Scler. 11, 159-165
-
(2005)
Mult. Scler.
, vol.11
, pp. 159-165
-
-
Yadav, V.1
Marracci, G.2
Lovera, J.3
Woodward, W.4
Bogardus, K.5
Marquardt, W.6
Shinto, L.7
Morris, C.8
Bourdette, D.9
-
32
-
-
33746274081
-
Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis
-
Chaudhary, P., Marracci, G. H. and Bourdette, D. N. (2006) Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 175, 87-96
-
(2006)
J. Neuroimmunol.
, vol.175
, pp. 87-96
-
-
Chaudhary, P.1
Marracci, G.H.2
Bourdette, D.N.3
-
33
-
-
59049099828
-
A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules
-
Mestre, L., Docagne, F., Correa, F., Loria, F., Hernangomez, M., Borrell, J. and Guaza, C. (2009) A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules. Mol. Cell. Neurosci. 40, 258-266
-
(2009)
Mol. Cell. Neurosci.
, vol.40
, pp. 258-266
-
-
Mestre, L.1
Docagne, F.2
Correa, F.3
Loria, F.4
Hernangomez, M.5
Borrell, J.6
Guaza, C.7
-
34
-
-
79953890808
-
Inhibitory effect of a-lipoic acid on platelet aggregation is mediated by PPARs
-
Chou, T. C., Shih, C. Y. and Chen, Y. T. (2011) Inhibitory effect of a-lipoic acid on platelet aggregation is mediated by PPARs. J. Agric. Food Chem. 59, 3050-3059
-
(2011)
J. Agric. Food Chem.
, vol.59
, pp. 3050-3059
-
-
Chou, T.C.1
Shih, C.Y.2
Chen, Y.T.3
-
35
-
-
0036499074
-
Peroxisome-proliferator-activated receptor-γ agonist 15-deoxy-(12,14)-prostaglandin J2 ameliorates experimental autoimmune encephalomyelitis
-
Diab, A., Deng, C., Smith, J. D., Hussain, R. Z., Phanavanh, B., Lovett-Racke, A. E., Drew, P. D. and Racke, M. K. (2002) Peroxisome-proliferator-activated receptor-γ agonist 15-deoxy-(12,14)-prostaglandin J2 ameliorates experimental autoimmune encephalomyelitis. J. Immunol. 168, 2508-2515
-
(2002)
J. Immunol.
, vol.168
, pp. 2508-2515
-
-
Diab, A.1
Deng, C.2
Smith, J.D.3
Hussain, R.Z.4
Phanavanh, B.5
Lovett-Racke, A.E.6
Drew, P.D.7
Racke, M.K.8
-
36
-
-
25844473319
-
Protective effects of a peroxisomeproliferator- activated receptor-ß/d agonist in experimental autoimmune encephalomyelitis
-
Polak, P. E., Kalinin, S., Dello Russo, C., Gavrilyuk, V., Sharp, A., Peters, J. M., Richardson, J., Willson, T. M., Weinberg, G. and Feinstein, D. L. (2005) Protective effects of a peroxisomeproliferator- activated receptor-ß/d agonist in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 168, 65-75
-
(2005)
J. Neuroimmunol.
, vol.168
, pp. 65-75
-
-
Polak, P.E.1
Kalinin, S.2
Dello Russo, C.3
Gavrilyuk, V.4
Sharp, A.5
Peters, J.M.6
Richardson, J.7
Willson, T.M.8
Weinberg, G.9
Feinstein, D.L.10
-
37
-
-
14844282813
-
Peroxisome-proliferator-activated receptor-γ agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis
-
Storer, P. D., Xu, J., Chavis, J. and Drew, P. D. (2005) Peroxisome-proliferator-activated receptor-γ agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. J. Neuroimmunol. 161, 113-122
-
(2005)
J. Neuroimmunol.
, vol.161
, pp. 113-122
-
-
Storer, P.D.1
Xu, J.2
Chavis, J.3
Drew, P.D.4
-
38
-
-
0032847680
-
Peroxisome-proliferatoractivated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction
-
Jackson, S. M., Parhami, F., Xi, X. P., Berliner, J. A, Hsueh, W. A., Law, R. E. and Demer, L. L. (1999) Peroxisome-proliferatoractivated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arterioscler. Thromb. Vasc. Biol. 19, 2094-2104
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2094-2104
-
-
Jackson, S.M.1
Parhami, F.2
Xi, X.P.3
Berliner, J.A.4
Hsueh, W.A.5
Law, R.E.6
Demer, L.L.7
-
39
-
-
56449084136
-
Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis
-
Klotz, L., Schmidt, S., Heun, R., Klockgether, T. and Kolsch, H. (2009) Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis. Neurosci. Lett. 449, 81-83
-
(2009)
Neurosci. Lett.
, vol.449
, pp. 81-83
-
-
Klotz, L.1
Schmidt, S.2
Heun, R.3
Klockgether, T.4
Kolsch, H.5
-
40
-
-
0344153921
-
Peroxisome-proliferator-activated receptor-γ - deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis
-
Natarajan, C., Muthian, G., Barak, Y., Evans, R. M. and Bright, J. J. (2003) Peroxisome-proliferator-activated receptor-γ - deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. J. Immunol. 171, 5743-5750
-
(2003)
J. Immunol.
, vol.171
, pp. 5743-5750
-
-
Natarajan, C.1
Muthian, G.2
Barak, Y.3
Evans, R.M.4
Bright, J.J.5
-
41
-
-
26244450392
-
a-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells
-
Ogborne, R. M., Rushworth, S. A. and O'Connell, M. A. (2005) a-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells. Arterioscler. Thromb. Vasc. Biol. 25, 2100-2105
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2100-2105
-
-
Ogborne, R.M.1
Rushworth, S.A.2
O'Connell, M.A.3
-
42
-
-
78649284975
-
Erythropoietin enhances endogenous haem oxygenase-1 and represses immune responses to ameliorate experimental autoimmune encephalomyelitis
-
Chen, S. J., Wang, Y. L., Lo, W. T., Wu, C. C., Hsieh, C. W., Huang, C. F., Lan, Y. H., Wang, C. C., Chang, D. M. and Sytwu, H. K. (2010) Erythropoietin enhances endogenous haem oxygenase-1 and represses immune responses to ameliorate experimental autoimmune encephalomyelitis. Clin. Exp. Immunol. 162, 210-223
-
(2010)
Clin. Exp. Immunol.
, vol.162
, pp. 210-223
-
-
Chen, S.J.1
Wang, Y.L.2
Lo, W.T.3
Wu, C.C.4
Hsieh, C.W.5
Huang, C.F.6
Lan, Y.H.7
Wang, C.C.8
Chang, D.M.9
Sytwu, H.K.10
-
43
-
-
0034625485
-
Cyclopentenone prostaglandin 15-deoxy-(12,14)-prostaglandin J2 acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells
-
Koppal, T., Petrova, T. V. and Van Eldik, L. J. (2000) Cyclopentenone prostaglandin 15-deoxy-(12,14)-prostaglandin J2 acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells. Brain Res. 867, 115-121
-
(2000)
Brain Res.
, vol.867
, pp. 115-121
-
-
Koppal, T.1
Petrova, T.V.2
Van Eldik, L.J.3
-
44
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L. and Kuchroo, V. K. (2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
45
-
-
56149125346
-
Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
-
O'Connor, R. A., Prendergast, C. T., Sabatos, C. A., Lau, C. W., Leech, M. D., Wraith, D. C. and Anderton, S. M. (2008) Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J. Immunol. 181, 3750-3754
-
(2008)
J. Immunol.
, vol.181
, pp. 3750-3754
-
-
O'Connor, R.A.1
Prendergast, C.T.2
Sabatos, C.A.3
Lau, C.W.4
Leech, M.D.5
Wraith, D.C.6
Anderton, S.M.7
-
46
-
-
35148835215
-
CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells
-
Ponomarev, E. D., Maresz, K., Tan, Y. and Dittel, B. N. (2007) CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells. J. Neurosci. 27, 10714-10721
-
(2007)
J. Neurosci.
, vol.27
, pp. 10714-10721
-
-
Ponomarev, E.D.1
Maresz, K.2
Tan, Y.3
Dittel, B.N.4
-
47
-
-
0032525044
-
A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice
-
Falcone, M., Rajan, A. J., Bloom, B. R. and Brosnan, C. F. (1998) A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice. J. Immunol. 160, 4822-4830
-
(1998)
J. Immunol.
, vol.160
, pp. 4822-4830
-
-
Falcone, M.1
Rajan, A.J.2
Bloom, B.R.3
Brosnan, C.F.4
-
48
-
-
0036838536
-
Cutting edge: CD4+ CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
-
Kohm, A. P., Carpentier, P. A., Anger, H. A. and Miller, S. D. (2002) Cutting edge: CD4+ CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169, 4712-4716
-
(2002)
J. Immunol.
, vol.169
, pp. 4712-4716
-
-
Kohm, A.P.1
Carpentier, P.A.2
Anger, H.A.3
Miller, S.D.4
-
49
-
-
65449122461
-
Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg
-
Stephens, L. A., Malpass, K. H. and Anderton, S. M. (2009) Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg. Eur. J. Immunol. 39, 1108-1117
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 1108-1117
-
-
Stephens, L.A.1
Malpass, K.H.2
Anderton, S.M.3
-
50
-
-
77955343205
-
Peroxisome-proliferator-activated receptor d limits the expansion of pathogenic Th cells during central nervous system autoimmunity
-
Dunn, S. E., Bhat, R., Straus, D. S., Sobel, R. A., Axtell, R., Johnson, A., Nguyen, K., Mukundan, L., Moshkova, M., Dugas, J. C. et al. (2010) Peroxisome-proliferator-activated receptor d limits the expansion of pathogenic Th cells during central nervous system autoimmunity. J. Exp. Med. 207, 1599-1608
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1599-1608
-
-
Dunn, S.E.1
Bhat, R.2
Straus, D.S.3
Sobel, R.A.4
Axtell, R.5
Johnson, A.6
Nguyen, K.7
Mukundan, L.8
Moshkova, M.9
Dugas, J.C.10
-
51
-
-
33846303501
-
Lipoic acid stimulates cAMP production in T lymphocytes and NK cells
-
Schillace, R. V., Pisenti, N., Pattamanuch, N., Galligan, S., Marracci, G. H., Bourdette, D. N. and Carr, D. W. (2007) Lipoic acid stimulates cAMP production in T lymphocytes and NK cells. Biochem. Biophys. Res. Commun. 354, 259-264
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.354
, pp. 259-264
-
-
Schillace, R.V.1
Pisenti, N.2
Pattamanuch, N.3
Galligan, S.4
Marracci, G.H.5
Bourdette, D.N.6
Carr, D.W.7
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