메뉴 건너뛰기




Volumn 449, Issue 1, 2009, Pages 81-83

Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis

Author keywords

Multiple sclerosis; Polymorphism; PPAR

Indexed keywords

ALANINE; LEUCINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROLINE; VALINE;

EID: 56449084136     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.10.066     Document Type: Article
Times cited : (26)

References (22)
  • 2
    • 0042412157 scopus 로고    scopus 로고
    • Polymorphism in the peroxisome proliferator-activated receptor alpha gene influences the risk for Alzheimer's disease
    • Brune S., Kolsch H., Ptok U., Majores M., Schulz A., Schlosser R., Rao M.L., Maier W., and Heun R. Polymorphism in the peroxisome proliferator-activated receptor alpha gene influences the risk for Alzheimer's disease. J. Neural Transm. 110 (2003) 1041-1050
    • (2003) J. Neural Transm. , vol.110 , pp. 1041-1050
    • Brune, S.1    Kolsch, H.2    Ptok, U.3    Majores, M.4    Schulz, A.5    Schlosser, R.6    Rao, M.L.7    Maier, W.8    Heun, R.9
  • 3
    • 33746730443 scopus 로고    scopus 로고
    • PPAR-gamma gene polymorphisms and psoriatic arthritis
    • Butt C., Gladman D., and Rahman P. PPAR-gamma gene polymorphisms and psoriatic arthritis. J. Rheumatol. 33 (2006) 1631-1633
    • (2006) J. Rheumatol. , vol.33 , pp. 1631-1633
    • Butt, C.1    Gladman, D.2    Rahman, P.3
  • 4
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • Deeb S.S., Fajas L., Nemoto M., Pihlajamaki J., Mykkanen L., Kuusisto J., Laakso M., Fujimoto W., and Auwerx J. A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat. Genet. 20 (1998) 284-287
    • (1998) Nat. Genet. , vol.20 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3    Pihlajamaki, J.4    Mykkanen, L.5    Kuusisto, J.6    Laakso, M.7    Fujimoto, W.8    Auwerx, J.9
  • 7
    • 4243353569 scopus 로고    scopus 로고
    • Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome
    • Frederiksen L., Brodbaek K., Fenger M., Jorgensen T., Borch-Johnsen K., Madsbad S., and Urhammer S.A. Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome. J. Clin. Endocrinol. Metab. 87 (2002) 3989-3992
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 3989-3992
    • Frederiksen, L.1    Brodbaek, K.2    Fenger, M.3    Jorgensen, T.4    Borch-Johnsen, K.5    Madsbad, S.6    Urhammer, S.A.7
  • 8
    • 33244482536 scopus 로고    scopus 로고
    • Combinatorial roles of nuclear receptors in inflammation and immunity
    • Glass C.K., and Ogawa S. Combinatorial roles of nuclear receptors in inflammation and immunity. Nat. Rev. Immunol. 6 (2006) 44-55
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 44-55
    • Glass, C.K.1    Ogawa, S.2
  • 9
    • 0009573338 scopus 로고    scopus 로고
    • J.L. Haines, M. Ter-Minassian, A. Bazyk, J.F. Gusella, D.J. Kim, H. Terwedow, M.A. Pericak-Vance, J.B. Rimmler, C.S. Haynes, A.D. Roses, A. Lee, B. Shaner, M. Menold, E. Seboun, R.P. Fitoussi, C. Gartioux, C. Reyes, F. Ribierre, G. Gyapay, J. Weissenbach, S.L. Hauser, D.E. Goodkin, R. Lincoln, K. Usuku, J.R. Oksenberg, A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group, Nat. Genet. 13 (1996) 469-471.
    • J.L. Haines, M. Ter-Minassian, A. Bazyk, J.F. Gusella, D.J. Kim, H. Terwedow, M.A. Pericak-Vance, J.B. Rimmler, C.S. Haynes, A.D. Roses, A. Lee, B. Shaner, M. Menold, E. Seboun, R.P. Fitoussi, C. Gartioux, C. Reyes, F. Ribierre, G. Gyapay, J. Weissenbach, S.L. Hauser, D.E. Goodkin, R. Lincoln, K. Usuku, J.R. Oksenberg, A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group, Nat. Genet. 13 (1996) 469-471.
  • 10
    • 0036546066 scopus 로고    scopus 로고
    • New concepts in the immunopathogenesis of multiple sclerosis
    • Hemmer B., Archelos J.J., and Hartung H.P. New concepts in the immunopathogenesis of multiple sclerosis. Nat. Rev. Neurosci. 3 (2002) 291-301
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 291-301
    • Hemmer, B.1    Archelos, J.J.2    Hartung, H.P.3
  • 11
    • 0036320727 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study
    • Herrmann S.M., Ringel J., Wang J.G., Staessen J.A., and Brand E. Peroxisome proliferator-activated receptor-gamma2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study. Diabetes 51 (2002) 2653-2657
    • (2002) Diabetes , vol.51 , pp. 2653-2657
    • Herrmann, S.M.1    Ringel, J.2    Wang, J.G.3    Staessen, J.A.4    Brand, E.5
  • 12
    • 26844468856 scopus 로고    scopus 로고
    • Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients
    • Klotz L., Schmidt M., Giese T., Sastre M., Knolle P., Klockgether T., and Heneka M.T. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. J. Immunol. 175 (2005) 4948-4955
    • (2005) J. Immunol. , vol.175 , pp. 4948-4955
    • Klotz, L.1    Schmidt, M.2    Giese, T.3    Sastre, M.4    Knolle, P.5    Klockgether, T.6    Heneka, M.T.7
  • 15
    • 0034607051 scopus 로고    scopus 로고
    • Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis
    • Masugi J., Tamori Y., Mori H., Koike T., and Kasuga M. Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis. Biochem. Biophys. Res. Commun. 268 (2000) 178-182
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 178-182
    • Masugi, J.1    Tamori, Y.2    Mori, H.3    Koike, T.4    Kasuga, M.5
  • 16
    • 0344153921 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis
    • Natarajan C., Muthian G., Barak Y., Evans R.M., and Bright J.J. Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. J. Immunol. 171 (2003) 5743-5750
    • (2003) J. Immunol. , vol.171 , pp. 5743-5750
    • Natarajan, C.1    Muthian, G.2    Barak, Y.3    Evans, R.M.4    Bright, J.J.5
  • 19
    • 0036320603 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism
    • Stumvoll M., and Haring H. The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism. Diabetes 51 (2002) 2341-2347
    • (2002) Diabetes , vol.51 , pp. 2341-2347
    • Stumvoll, M.1    Haring, H.2
  • 22
    • 23944448075 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma polymorphisms affect systemic inflammation and survival in end-stage renal disease patients starting renal replacement therapy
    • Yao Q., Nordfors L., Axelsson J., Heimburger O., Qureshi A.R., Barany P., Lindholm B., Lonnqvist F., Schalling M., and Stenvinkel P. Peroxisome proliferator-activated receptor gamma polymorphisms affect systemic inflammation and survival in end-stage renal disease patients starting renal replacement therapy. Atherosclerosis 182 (2005) 105-111
    • (2005) Atherosclerosis , vol.182 , pp. 105-111
    • Yao, Q.1    Nordfors, L.2    Axelsson, J.3    Heimburger, O.4    Qureshi, A.R.5    Barany, P.6    Lindholm, B.7    Lonnqvist, F.8    Schalling, M.9    Stenvinkel, P.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.