Transgenic mice expressing surface markers for IFN-γ and IL-4 producing cells

Molecular Immunology

Volumn 37, Issue 6, 2000, Pages 281-293

  Hsieh, Shie Liang ^a   Chen, Nien Jung ^a   Tarbell, Kristin ^b   Liao, Nan Shih ^c   Lai, Yein Gei ^c   Lee, Kun Hsiung ^d   Lee, Kin Mu ^a   Wu, Shinn Chih ^d   Sytwu, Huey Kang ^e   Han, Shou Hwa ^a   McDevitt, Hugh ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^d Pig Research Institute Taiwan   (Taiwan)

^e NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

T lymphocytes; T(H)1 T(H)2; Transgenic

Indexed keywords

BIOCHEMICAL MARKER; GAMMA INTERFERON; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; INTERFERON PRODUCTION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE;

3T3 CELLS; ANIMALS; ANTIGENS, THY-1; BASE SEQUENCE; DNA PRIMERS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; KINETICS; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); TH1 CELLS; TH2 CELLS; TRANSFECTION;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0033824989     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(00)00052-3     Document Type: Article

References (47)

1. Functional diversity of helper T lymphocytes
2. + T-cell subsets
3. Specific expression of surface interferon-gamma on interferon-gamma producing T-cells from mouse and man
4. Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells
5. Differential transcription directed by discrete gamma interferon promoter elements in naive and memory (effector) CD4 cells and CD8 cells
6. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues
7. + T cells
8. Isolation of a polysaccharide antigen from Schistosoma mansoni eggs
9. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
10. Heterogenecity of helper/inducer T lymphocytes II: Effects of interleukin 4 and interleukin 2 producing T cell clones on resting B lymphocytes
11. Molecular dissection of the mouse interleukin promoter
12. Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogens infection
13. Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor
14. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones
15. Preferential activation of TH2 cells in chronic graft-versus-host reaction
16. Human basophils release interleukin-4 after stimulation with Schistosoma mansoni egg antigen
17. The Th1/Th2-like switch in syphilitic infection: Is it detrimental?
18. Estrogen regulates the IFN-γ promoter
19. Regulation of Thy-1 gene expression in transgenic mice
20. A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer
21. Monoallelic expression of the interleukine-2 locus
22. + T cells through IL-12 produced by Listeria-induced macrophages
23. The role of the CD28 receptor during T cell response to antigen
24. CCR5 is characteristic of Th1 lymphocytes
25. + T cells from Schistosoma egg-induced granulomas: Analysis of Th cell cytokine coexpression ex vivo
26. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
27. Profiles of lymphokine activities and helper function for IgE in human T cell clones
28. The autoimmune infiltrate of Basedow's disease: Analysis of clonal level and comparison with Hashimoto's thyroiditis
29. CD-28 induced costimulation of T helper type 2 cells mediated by induction of responseness to interleukin 4
30. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
31. The expanding universe of T-cell subsets: TH1 TH2 and more
32. Mice with a fluorescent marker for interleukin 2 gene activation
33. B-cell outgrowth and ligand-specific production of IL-10 correlate with Th2 dominance in certain parasitic diseases
34. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies
35. Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
36. Regulation of IL-4 expression by activation of individual alleles
37. Predominant H-2 like broncho-alveolar T-lymphocyte population in atopic asthma
38. Selective expression of an interleukin-12 receptor component by human T helper 1 cells
39. CD28 costimulation promotes the production of Th2 cytokines
40. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
41. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
42. T helper cell immune dysfunction in asymptomatic, HIV-1-seropositive individuals: The role of TH1-TH2 cross-regulation
43. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
44. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines
45. Transcription of the interleukin 4 gene is regulated by multiple promoter elements
46. Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development
47. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells