Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor

Journal of Biological Chemistry

Volumn 288, Issue 27, 2013, Pages 19386-19400

  Floss, Doreen M ^a   Mrotzek, Simone ^a   Klöcker, Tobias ^a   Schröder, Jutta ^a   Grötzinger, Joachim ^b   Rose John, Stefan ^b   Scheller, Jürgen ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNE RESPONSE; CELLULAR ACTIVATION; DOMAIN-BINDING PROTEINS; FEEDBACK INHIBITION; INTRACELLULAR DOMAIN; SIGNAL TRANSDUCERS; SITE DIRECTED MUTAGENESIS; SUPPRESSOR OF CYTOKINE SIGNALING;

AMINO ACIDS; CELL SIGNALING; ENZYME ACTIVITY; IMMUNOLOGY; PHOSPHORYLATION; PROTEINS; SIGNAL TRANSDUCTION;

CHEMICAL ACTIVATION;

BINDING PROTEIN; GLUTAMINE DERIVATIVE; INTERLEUKIN 12 RECEPTOR BETA1; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; PHENYLALANINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; PROTEIN KINASE B; SRC HOMOLOGY 2 DOMAIN BINDING PROTEIN; STAT3 PROTEIN; TYROSYLPROPYLASPARAGINYLPHENYLALANYLGLUTAMINE; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL EXPANSION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE DELETION; HUMAN; INNATE IMMUNITY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TH17 CELL;

CYTOKINE; INTERLEUKIN; MAP KINASES (MAPKS); SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTOR;

AMINO ACID MOTIFS; ANIMALS; BINDING SITES; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; HELA CELLS; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MUTAGENESIS, SITE-DIRECTED; PEPTIDE MAPPING; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS;

EID: 84880057892     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.432153     Document Type: Article

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