Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling

Journal of Biological Chemistry

Volumn 274, Issue 4, 1999, Pages 1875-1878

  Naeger, Lisa K ^a   McKinney, Judi ^a   Salvekar, Anupama ^a   Hoey, Timothy ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12 RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; BINDING SITE; DNA BINDING; DRUG RECEPTOR BINDING; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; HELPER CELL; IMMUNE RESPONSE; KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

BASE SEQUENCE; BINDING SITES; DNA PRIMERS; DNA-BINDING PROTEINS; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; STAT4 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TYROSINE;

ANIMALIA;

EID: 0033593445     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.4.1875     Document Type: Article

References (35)

1. Trinchieri, G. (1995) Annu. Rev. Immunol. 13, 251-276
2. Hsieh, C., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O'Garra, A., and Murphy, K. M. (1993) Science 260, 547-549
3. Manetti, R., Parronchi, P., Guidizi, M. G., Piccinni, M.-P., Maggi, E., Trinchieri, G., and Romagnani, S. (1993) J. Exp. Med. 177, 1199-1204
4. Romagnani, S. (1996) Clin. Immunol. Immunopathol. 80, 225-235
5. Chua, A. O., Chizzonite, R., Desai, B. B., Truitt, T. P., Nunes, P., Minetti, L. J., Warrier, R. J., Preaky, D. H., Levine, J. F., Gately, M. K., and Gubler, U. (1994) J. Immunol. 153, 128-136
6. Preaky, D. H., Yang, H., Minetti, L. J., Chua, A. O., Nabavi, N., Wu, C. Y., Gately, M. K., and Gubler, U. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14002-14007
7. Szabo, S. J., Dighe, A. S., Gubler, U., and Murphy, K. M. (1997) J. Exp. Med. 185, 817-824
8. Rogge, L., Barberis-Maino, L., Biffi, M., Passini, N., Presky, D. H., Gubler, U., and Sinigaglia, F. (1997) J. Exp. Med. 185, 825-831
9. Bacon, C. B., McVicar, D. W., Ortaldo, J. R., Rees, R. C., O'Shea, J. J., and Johnston, J. A. (1995) J. Exp. Med. 181, 399-404
10. Zou, J., Presky, D. H., Wu, C.-Y., and Gubler, U. (1997) J. Biol. Chem. 272, 6073-6077
11. Zhong, Z., Wen, Z., and Darnell, J. E., Jr. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 4806-4810
12. Yamamoto, K., Quelle, F. W., Thierfelder, W. E., Kreider, B. L., Gilbert, D. J., Jenkins, N. A., Copeland, N. G., Silvennoinen, O., and Ihle, J. N. (1994) Mol. Cell. Biol. 14, 4342-4349
13. Jacobson, N. G., Szabo, S. J., Weber-Nordt, R. M., Zhong, Z., Schreiber, R. D., and Murphy, K. M. (1995) J. Exp. Med. 181, 1755-1762
14. Yu, C.-R., Lin, J.-X., Fink, D. W., Akira, S., Bloom, E. T., and Yamauchi, A. (1996) J. Immunol. 157, 126-137
15. Gollob, J. A., Murphy, E. A., Mahajan, S., Schnipper, C. P., Ritz, J., and Frank, D. A. (1998) Blood 91, 1341-1354
16. Schindler, U., Hoey, T., and McKnight, S. L. (1996) Genes Cells 1, 507-515
17. Chen, C., and Okayama, H. (1987) Mol. Cell. Biol. 7, 2745-2752
18. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
19. Hou, J., Schindler, U., Henzel, W. J., Ho, T. Z., Brasseur, M., and McKnight, S. L. (1994) Science 285, 1701-1706
20. Schindler, U., Wu, P., Rothe, M., Brasseur, M., and McKnight, S. L. (1995) Immunity 2, 689-697
21. Cho, S. S., Bacon, C. M., Sudarshan, C., Rees, R. C., Finbloom, D., Pine, R., and O'Shea, J. J. (1996) J. Immunol. 157, 4781-4789
22. Muller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, T., Darnell, J. E., Stark, G. R., and Kerr, I. M. (1993) EMBO J. 12, 4221-4228
23. Xu, X., Sun, Y.-L., and Hoey, T. (1996) Science 273, 794-797
24. Bacon, C. M., Petricoin, E. F., III, Ortaldo, J. R., Rees, R. C., Larner, A. C., Johnston, J. A., and O'Shea, J. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7307-7311
25. Kaplan, M. H., Sun, Y.-L., Hoey, T., and Grusby, M. J. (1996) Nature 382, 174-177
26. Thierfelder, W. E., van Duersen, J. M., Yamamoto, K., Tripp, R. A., Sarawar, S. R., Carson, R. T., Sangster, M. Y., Vignali, D. A., Doherty, P. C., Grosveld, G. C., and Ihle, J. N. (1996) Nature 382, 171-174
27. Darnell, J. E., Jr., Kerr, I. A., and Stark, G. R. (1994) Science 264, 1415-1421
28. Schindler, C., and Darnell, J. E., Jr. (1995) Annu. Rev. Biochem. 64, 621-651
29. Sadowski, H. B., Shuai, K., Darnell, J. E., Jr., and Gilman, M. Z. (1993) Science 261, 1739-1745
30. Stahl, N., Farruggella, T. J., Boulton, T. G., Zhong, Z., Darnell, Jr., J. E., and Yancopoulos, G. D. (1995) Science 267, 1349-1353
31. Greenlund, A. C., Farrar, M. A., Viviano, B. L., and Schreiber, R. D. (1994) EMBO J. 13, 1591-1600
32. Farrar, M. A., Campbell, J. D., and Schreiber, R. D. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 11706-11710
33. Yan, H., Greenlund, A. C., Gupta, S., Lim, J. T. E., Schreiber, R. D., Schindler, C., and Krowleski, J. J. (1996) EMBO J. 15, 1064-1074
34. Pignata, C., Sanghera, J. S., Cossette, L., Pelech, S. L., and Ritz, J. (1994) Blood 83, 184-190
35. Pignata, C., Prasad, K. V. S., Hallek, M., Druker, B., Rudd, C. E., Robertson, M. J., and Ritz, J. (1995) Cell. Immunol. 165, 211-216