Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells

Journal of Biological Chemistry

Volumn 288, Issue 27, 2013, Pages 19321-19329

  Xia, Yan ^a,b   Yang, Weiwei ^a   Bu, Wen ^c   Ji, Haitao ^a   Zhao, Xueqiang ^a   Zheng, Yanhua ^a   Lin, Xin ^a,d   Li, Yi ^c   Lu, Zhimin ^a,d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NANJING UNIVERSITY   (China)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER THERAPY; CHEMORESISTANCE; CHEMOTHERAPEUTIC DRUGS; DIFFERENTIAL REGULATION; DOWN-REGULATION; MOLECULAR TARGETS; PROMOTER REGION; UBIQUITYLATION;

CELL DEATH; MAMMALS; PLATINUM COMPOUNDS; TUMORS;

GENE EXPRESSION;

CASPASE 8; CASPASE 9; CISPLATIN; CYTOCHROME C; PROTEIN C JUN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST TUMOR; CANCER CELL; CANCER INHIBITION; CANCER RESISTANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG EFFICACY; GENE EXPRESSION; MDR1 GENE; MOUSE; NONHUMAN; ONCOGENE; OSMOTIC STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TUMOR GROWTH; UBIQUITINATION; UPREGULATION;

APOPTOSIS; C-JUN; C-JUN N-TERMINAL KINASE (JNK); CASPASE; JUN TRANSCRIPTION FACTOR; UBIQUITIN;

ANIMALS; ANTINEOPLASTIC AGENTS; CASPASE 9; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MAP KINASE KINASE KINASE 1; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 9; P-GLYCOPROTEIN; PROTO-ONCOGENE PROTEINS C-JUN; UBIQUITINATION;

EID: 84880048265     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.475442     Document Type: Article

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