Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Chen, Peila ^a   O'Neal, Jamye F ^a   Ebelt, Nancy D ^a   Cantrell, Michael A ^a   Mitra, Shreya ^a   Nasrazadani, Azadeh ^a   Vandenbroek, Tracy L ^a   Heasley, Lynn E ^b   van den Berg, Carla L ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1; MITOGEN ACTIVATED PROTEIN KINASE 9; PROTEIN P53; REPLICATION FACTOR A; REPLICATION LICENSING FACTOR CDT1; 53BP1 PROTEIN, MOUSE; CAFFEINE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; GAMMA H2AX PROTEIN, MOUSE; GAMMA-H2AX PROTEIN, MOUSE; HISTONE; SIGNAL PEPTIDE; VIRUS T ANTIGEN;

ADENOVIRUS; ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CELL; CELL DEATH; CELL DIVISION; CELL STRESS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENE LOCATION; GENE OVEREXPRESSION; GENOMIC INSTABILITY; IN VITRO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SINGLE STRANDED DNA BREAK; ULTRAVIOLET RADIATION; VIRUS EXPRESSION; WILD TYPE; ANIMAL; CELL CYCLE G1 PHASE; DISEASE MODEL; DNA REPLICATION; DRUG EFFECT; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGICAL STRESS; PRECANCER; TRANSGENE;

MUS;

ANEUPLOIDY; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CAFFEINE; CELL DEATH; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA REPLICATION; FEMALE; G1 PHASE; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HISTONES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 9; PRECANCEROUS CONDITIONS; REPLICATION PROTEIN A; STRESS, PHYSIOLOGICAL; TRANSGENES;

EID: 77956271488     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010443     Document Type: Article

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