Caspase-10-mediated heat shock protein 90β cleavage promotes UVB irradiation-induced cell apoptosis

Molecular and Cellular Biology

Volumn 29, Issue 13, 2009, Pages 3657-3664

  Chen, Hehua ^a   Xia, Yan ^a   Fang, Dexing ^a   Hawke, David ^a   Lu, Zhimin ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 10; CASPASE 8; FAS LIGAND; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION; ULTRAVIOLET B RADIATION;

AMINO ACID CHLOROMETHYL KETONES; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CASPASE 10; CASPASE 8; CELL LINE; ENZYME ACTIVATION; FAS LIGAND PROTEIN; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; ULTRAVIOLET RAYS;

EID: 67650084825     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01640-08     Document Type: Article

References (33)

1. Arya, R., M. Mallik, and S. C. Lakhotia. 2007. Heat shock genes-integrating cell survival and death. J. Biosci. 32:595-610.
2. Basso, A. D., D. B. Solit, G. Chiosis, B. Giri, P. Tsichlis, and N. Rosen. 2002. Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function. J. Biol. Chem. 277:39858-39866.
3. Bishop, S. C., J. A. Burlison, and B. S. Blagg. 2007. Hsp90: a novel target for the disruption of multiple signaling cascades. Curr. Cancer Drug Targets 7:369-388.
4. Budihardjo, I., H. Oliver, M. Lutter, X. Luo, and X. Wang. 1999. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15:269-290.
5. Chen, G., P. Cao, and D. V. Goeddel. 2002. TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. Mol. Cell 9:401-410.
6. Chen, M., and J. Wang. 2002. Initiator caspases in apoptosis signaling pathways. Apoptosis 7:313-319.
7. Csermely, P., T. Schnaider, C. Soti, Z. Prohaszka, and G. Nardai. 1998. The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review. Pharmacol. Ther. 79:129-168.
8. Green, D. R., and J. C. Reed. 1998. Mitochondria and apoptosis. Science 281:1309-1312.
9. Hartl, F. U., and M. Hayer-Hartl. 2002. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295:1852-1858.
10. Hill, L. L., A. Ouhtit, S. M. Loughlin, M. L. Kripke, H. N. Ananthaswamy, and L. B. Owen-Schaub. 1999. Fas ligand: a sensor for DNA damage critical in skin cancer etiology. Science 285:898-900.
11. Juo, P., C. J. Kuo, J. Yuan, and J. Blenis. 1998. Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Curr. Biol. 8:1001-1008.
12. Juo, P., M. S. Woo, C. J. Kuo, P. Signorelli, H. P. Biemann, Y. A. Hannun, and J. Blenis. 1999. FADD is required for multiple signaling events downstream of the receptor Fas. Cell Growth Differ. 10:797-804.
13. Kim, T. S., C. Y. Jang, H. D. Kim, J. Y. Lee, B. Y. Ahn, and J. Kim. 2006. Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation. Mol. Biol. Cell 17:824-833.
14. Kischkel, F. C., D. A. Lawrence, A. Tinel, H. LeBlanc, A. Virmani, P. Schow, A. Gazdar, J. Blenis, D. Arnott, and A. Ashkenazi. 2001. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J. Biol. Chem. 276:46639-46646.
15. Lewis, J., A. Devin, A. Miller, Y. Lin, Y. Rodriguez, L. Neckers, and Z. G. Liu. 2000. Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. J. Biol. Chem. 275:10519-10526.
16. Lu, Z., S. Xu, C. Joazeiro, M. H. Cobb, and T. Hunter. 2002. The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2. Mol. Cell 9:945-956.
17. Martin, D. A., R. M. Siegel, L. Zheng, and M. J. Lenardo. 1998. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal. J. Biol. Chem. 273:4345-4349.
18. Muzio, M., B. R. Stockwell, H. R. Stennicke, G. S. Salvesen, and V. M. Dixit. 1998. An induced proximity model for caspase-8 activation. J. Biol. Chem. 273:2926-2930.
19. Nathan, D. F., M. H. Vos, and S. Lindquist. 1997. In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc. Natl. Acad. Sci. USA 94:12949-12956.
20. Niikura, Y., T. Nonaka, and S. Imajoh-Ohmi. 2002. Monitoring of caspase-8/FLICE processing and activation upon Fas stimulation with novel antibodies directed against a cleavage site for caspase-8 and its substrate, FLICElike inhibitory protein (FLIP). J. Biochem. 132:53-62.
21. Pandey, P., A. Saleh, A. Nakazawa, S. Kumar, S. M. Srinivasula, V. Kumar, R. Weichselbaum, C. Nalin, E. S. Alnemri, D. Kufe, and S. Kharbanda. 2000. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J. 19:4310-4322.
22. Pratt, W. B. 1998. The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors. Proc. Soc. Exp. Biol. Med. 217:420-434.
23. Reed, J. C., K. Doctor, A. Rojas, J. M. Zapata, C. Stehlik, L. Fiorentino, J. Damiano, W. Roth, S. Matsuzawa, R. Newman, S. Takayama, H. Marusawa, F. Xu, G. Salvesen, and A. Godzik. 2003. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 13:1376-1388.
24. Sato, S., N. Fujita, and T. Tsuruo. 2000. Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. USA 97:10832-10837.
25. Sreedhar, A. S., E. Kalmar, P. Csermely, and Y. F. Shen. 2004. Hsp90 isoforms: functions, expression and clinical importance. FEBS Lett. 562: 11-15.
26. Tibbetts, M. D., L. Zheng, and M. J. Lenardo. 2003. The death effector domain protein family: regulators of cellular homeostasis. Nat. Immunol. 4:404-409.
27. Wang, J., H. J. Chun, W. Wong, D. M. Spencer, and M. J. Lenardo. 2001. Caspase-10 is an initiator caspase in death receptor signaling. Proc. Natl. Acad. Sci. USA 98:13884-13888.
28. Whitesell, L., and S. L. Lindquist. 2005. HSP90 and the chaperoning of cancer. Nat. Rev. Cancer 5:761-772.
29. Xia, Y., J. Wang, T. J. Liu, W. K. Yung, T. Hunter, and Z. Lu. 2007. c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Mol. Cell 25:219-232.
30. Yan, N., and Y. Shi. 2005. Mechanisms of apoptosis through structural biology. Annu. Rev. Cell Dev. Biol. 21:35-56.
31. Zhang, R., D. Luo, R. Miao, L. Bai, Q. Ge, W. C. Sessa, and W. Min. 2005. Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis. Oncogene 24:3954-3963.
32. Zhao, C., and E. Wang. 2004. Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts. Cell Signal. 16:313-321.
33. Zhuang, L., B. Wang, and D. N. Sauder. 2000. Molecular mechanism of ultraviolet-induced keratinocyte apoptosis. J. Interferon Cytokine Res. 20: 445-454.