Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation

Journal of Immunology

Volumn 184, Issue 4, 2010, Pages 1849-1857

  Tan, Andy Hee Meng ^a   Lam, Kong Peng ^a  

^a AGENCY FOR SCIENCE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 22; INTERLEUKIN 23 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; STAT5 PROTEIN; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; IL17A PROTEIN, MOUSE; NITRILE; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOREGULATION; CELL MATURATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENZYME INHIBITION; GENE EXPRESSION; IN VITRO STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TH17 CELL; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HELPER CELL; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; TRANSPLANTATION; TUMOR CELL LINE;

ANIMALS; BUTADIENES; CELL DIFFERENTIATION; CELL LINE, TUMOR; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTERLEUKIN-17; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRILES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 77949901838     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901509     Document Type: Article

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