Paxillin phosphorylation counteracts proteoglycan-mediated inhibition of axon regeneration

Experimental Neurology

Volumn 248, Issue , 2013, Pages 157-169

  Kuboyama, Tomoharu ^a,b   Luo, Xueting ^c   Park, Kevin ^c   Blackmore, Murray G ^c,d   Tojima, Takuro ^a,e   Tohda, Chihiro ^b   Bixby, John L ^c   Lemmon, Vance P ^c   Kamiguchi, Hiroyuki ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c UNIVERSITY OF MIAMI   (United States)

^d MARQUETTE UNIVERSITY   (United States)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Aggrecan; Axon regeneration; Dystrophic endball; Optic nerve; P21 activated kinase; Paxillin; Point contact; Protein kinase A

Indexed keywords

ADENOVIRUS VECTOR; AGGRECAN; COMPLEMENTARY DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; KT 5720; LAMININ; MYRISTOYLATED PROTEIN KINASE INHIBITOR (14-22) AMIDE; P21 ACTIVATED KINASE 1; PAXILLIN; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INTRACELLULAR SIGNALING; NERVE CELL CULTURE; NERVE CELL LESION; NERVE CRUSH; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NONHUMAN; OPTIC NERVE INJURY; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; RETINA INJURY; SPINAL GANGLION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

AGGRECAN; AXON REGENERATION; DYSTROPHIC ENDBALL; OPTIC NERVE; P21-ACTIVATED KINASE; PAXILLIN; POINT CONTACT; PROTEIN KINASE A;

AGGRECANS; ANIMALS; AXONS; CELL MOVEMENT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; GANGLIA, SPINAL; NERVE REGENERATION; NEURONS; PAXILLIN; PHOSPHORYLATION; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84880011368     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.06.011     Document Type: Article

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