Proteoglycans in the developing brain: New conceptual insights for old proteins

Physiological Reviews

Volumn 80, Issue 4, 2000, Pages 1267-1290

  Bandtlow, C E ^a   Zimmermann, D R ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; GLYCOSAMINOGLYCAN; GLYPICAN; LIGAND; PROTEIN; PROTEOCHONDROITIN SULFATE; PROTEOGLYCAN; PROTEOHEPARAN SULFATE; SYNDECAN;

BRAIN DEVELOPMENT; GLIA CELL; HUMAN; LIGAND BINDING; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NERVE SPROUTING; NERVOUS SYSTEM DEVELOPMENT; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SYNAPTIC TRANSMISSION;

EID: 0033778942     PISSN: 00319333     EISSN: None     Source Type: Journal    
DOI: 10.1152/physrev.2000.80.4.1267     Document Type: Review

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167. Characterization of the type-1 repeat from thyroglobulin, a cysteine-rich module found in proteins from different families
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170. PSA-NCAM is required for activity-induced synaptic plasticity
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173. Characterization of the complete genomic structure of the human versican gene and functional analysis of its promoter
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185. GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC 4 and is colocalized with GPC5 on human chromosome 13
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200. A new A 4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors
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207. Molecular interactions of the syndecan core proteins
208. Mapping of a defined neurocan binding site to distinct domains of tenascin-C
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210. Structure and chromosomal localization of the mouse neurocan gene
211. Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain
212. Sequence and chromosomal localization of the mouse brevican gene
213. Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3)
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217. Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
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219. Structural and electron microscopic analysis of neurocan and recombinant neurocan fragments
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221. The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
222. Brain extracellular matrix
223. Structure and chromosomal localization of the mammalian agrin gene
224. Structure and expression of a rat agrin
225. Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity
226. Common molecular mechanisms in field- and agrin-induced acetylcholine receptor clustering
227. Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity
228. Expression of polypeptide variants of receptor-type protein tyrosine phosphatase beta: The secreted form, phosphacan, increases dramatically during embryonic development and modulates glial cell behavior in vitro
229. Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons
230. Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): Two amino acids length difference to human and murine homologues
231. Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins
232. APP gene family. Alternative splicing generates functionally related isoforms
233. Expression of the APP gene family in brain cells, brain development and aging
234. Molecular polymorphism of a cell surface proteoglycan: Distinct structures on simple and stratified epithelia
235. The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain
236. Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain
237. Molecular cloning of syndecan, an integral membrane proteoglycan
238. Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain
239. Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors?
240. Brain derived versican V2 is a potent inhibitor of axonal growth
241. Versican V2 is a major extracellular matrix component of the mature bovine brain
242. Early lesions of superior colliculus: Factors affecting the formation of abnormal retinal projections
243. Brain aggrecan
244. Increased collateral sprouting of primary afferents in the myelin-free spinal cord
245. Transcripts for secreted and GPI-anchored brevican are differentially distributed in rat brain
246. Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms
247. Effects of a neurotrophic factor (FGF) on development, regeneration and synaptic plasticity of central neurons
248. Genetic analysis of functions for cell surface proteoglycans
249. The relationship between the geniculocortical afferents and their cortical target cells during development of the cat's primary visual cortex
250. Changes in the distribution of extracellular matrix components accompany early morphogenetic events of mammalian cortical development
251. cDNA cloning of PG-M, a large chondroitin sulfate proteoglycan expressed during chondrogenesis in chick limb buds. Alternative spliced multiforms of PG-M and their relationships to versican
252. Neurons as well as astrocytes express proteoglycan-type protein tyrosine phosphatase zeta/RPTPbeta: Analysis of mice in which the PTPzeta/RPTPbeta gene was replaced with the LacZ gene
253. Chondroitin sulfate proteoglycan form of the Alzheimer's beta-amyloid precursor
254. The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and is produced by astrocytes but not by neurons in primary neural cultures
255. Brain-specific receptor-type protein-tyrosine phosphatase RPTP beta is a chondroitin sulfate proteoglycan in vivo
256. Characterization of ryudocan glycosaminoglycan acceptor sites
257. Cell-specific regulation of agrin RNA splicing in the chick ciliary ganglion
258. Sulfated proteoglycans on astroglial barriers inhibit neurite outgrowth in vitro
259. Molecular and cellular characterization of the glial roof plate of the spinal cord and optic tectum: A possible role for a proteoglycan in the development of an axon barrier
260. A chondroitin sulfate proteoglycan may influence the direction of retinal ganglion cell outgrowth
261. OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2
262. Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation
263. Mapping of the syndecan genes in the mouse: Linkage with members of the myc gene family
264. Drosophila syndecan: Conservation of a cell-surface heparan sulfate proteoglycan
265. Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan
266. Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen
267. Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican
268. Cerebroglycan: An integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation
269. Tissue- and age-specific expression patterns of alternatively spliced agrin mRNA transcripts in embryonic rat suggest novel developmental roles
270. Interaction of astrochondrin with extracellular matrix components and its involvement in astrocyte process formation and cerebellar granule cell migration
271. Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation
272. Embryonic expression patterns of Xenopus syndecans
273. Distribution of hyaluronic acid and chondroitin sulfate proteoglycans in the presumptive aganglionic terminal bowel of ls/ls fetal mice: An ultrastructural analysis
274. Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site
275. Novel regulatioh of chondroitin sulfate glycosaminoglycan modification of amyloid precursor protein and its homologue, APLP2
276. Developmental expression and alternative splicing of chick agrin RNA
277. The membrane-sparming proteoglycan NG2 binds to collagens V and VI through the central nongiobular domain of its core protein
278. Proteoglycans and hyaluronan in morphogenesis and differentiation
279. Agrin is a heparan sulfate proteoglycan
280. Identification of a novel alternatively spliced agrin mRNA that is preferentially expressed in non-neuronal cells
281. cDNA that encodes active agrin
282. The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila
283. Increased lesion-induced sprouting of corticospinal fibres in the myelin-free rat spinal cord
284. Clinical overlap of Beckwith-Wiedemann, Perlman and Simpson-Golabi-Behmel syndromes: A diagnostic pitfall
285. Assignment of the human glypican gene (GPC1) to 2q35-q37 by fluorescence in situ hybridization
286. Influence of glycosaminoglycans on neurite morphology and outgrowth patterns in vitro
287. Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans
288. Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family
289. GPC4, the gene for human K-glypican, flanks GPC3 on Xq26: Deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome
290. Structural organization and genomic sequence of mouse syndecan-1 gene
291. Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor
292. Essential role of heparan sulfates in axon navigation and targeting in the developing visual system
293. A role for proteoglycans in the guidance of a subset of pioneer axons in cultured embryos of the cockroach
294. Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor
295. Neuroglycan C, a novel membrane-spanning chondroitin sulfate proteoglycan that is restricted to the brain
296. K-glypican: A novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney
297. Glypicans: A growing trend
298. An experimental analysis of in vivo guidance cues used by axons of spinal interneurons in the chick embryo: Evidence for chemotropism and related guidance mechanisms
299. The brain chondroitin sulfate proteoglycan brevican associates with astrocytes ensheathing cerebellar glomeruli and inhibits neurite outgrowth from granule neurons
300. Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family
301. cDNA cloning and the identification of an aggrecanase-like cleavage site in rat brevican
302. Chondroitin sulfate proteoglycan (PG-M-like proteoglycan) is involved in the binding of hyaluronic acid to cellular fibronectin
303. Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module
304. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
305. Interactions between growing thalamocortical afferent axons and the neocortical primordium in normal and reeler mutant mice
306. Alternative splicing of the unique 'PLUS' domain of chicken PG-M/versican is developmentally regulated
307. Expression of PG-M (V3), an alternative splice form of PG-M without a chondroitin sulfate attachment region in mouse and human tissues
308. Versican is expressed in the proliferating zone in the epidermis and in association with the elastic network of the dermis
309. Multiple domains of the large fibroblast proteoglycan, versican
310. The syndecans, tuners of transmembrane signaling