Proteome-wide dysregulation by glucose-6-phosphate dehydrogenase (G6PD) reveals a novel protective role for G6PD in aflatoxin B1-mediated cytotoxicity

Journal of Proteome Research

Volumn 12, Issue 7, 2013, Pages 3434-3448

  Lin, Hsin Ru ^a   Wu, Chih Ching ^a   Wu, Yi Hsuan ^a   Hsu, Chia Wei ^a   Cheng, Mei Ling ^a   Chiu, Daniel Tsun Yee ^a,b  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

aflatoxin B1; epoxide hydrolase 1; glucose 6 phosphate dehydrogenase; iTRAQ; NADPH; xenobiotic metabolism

Indexed keywords

AFLATOXIN B1; EPOXIDE HYDROLASE; EPOXIDE HYDROLASE 1; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; OXIDIZING AGENT; PROTEOME; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL PROTECTION; CELL VIABILITY; CHEMICAL LABELING; CONTROLLED STUDY; CYTOTOXICITY; ENERGY METABOLISM; ENZYME ACTIVITY; GENE SILENCING; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; ISOBARIC TAG FOR RELATIVE AND ABSOLUTE QUANTIFICATION; LIQUID CHROMATOGRAPHY; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION STUDY; XENOBIOTIC METABOLISM;

AFLATOXIN B1; CELL LINE, TUMOR; ENERGY METABOLISM; GENE KNOCKDOWN TECHNIQUES; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE; HOMEOSTASIS; HUMANS; NADP; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTEOME; XENOBIOTICS;

EID: 84879987276     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr4002959     Document Type: Article

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