-
1
-
-
84855396777
-
American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Executive summary: heart disease and stroke statistics-2012 update: a report from the American Heart Association
-
Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Executive summary: heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation. 2012;125(1): 188-97.
-
(2012)
Circulation
, vol.125
, Issue.1
, pp. 188-197
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
Benjamin, E.J.4
Berry, J.D.5
Borden, W.B.6
Bravata, D.M.7
Dai, S.8
Ford, E.S.9
Fox, C.S.10
Fullerton, H.J.11
Gillespie, C.12
Hailpern, S.M.13
Heit, J.A.14
Howard, V.J.15
Kissela, B.M.16
Kittner, S.J.17
Lackland, D.T.18
Lichtman, J.H.19
Lisabeth, L.D.20
Makuc, D.M.21
Marcus, G.M.22
Marelli, A.23
Matchar, D.B.24
Moy, C.S.25
Mozaffarian, D.26
Mussolino, M.E.27
Nichol, G.28
Paynter, N.P.29
Soliman, E.Z.30
Sorlie, P.D.31
Sotoodehnia, N.32
Turan, T.N.33
Virani, S.S.34
Wong, N.D.35
Woo, D.36
Turner, M.B.37
more..
-
2
-
-
65249125762
-
Sex differences in stroke epidemiology: a systematic review
-
Appelros P, Stegmayr B, Terent A. Sex differences in stroke epidemiology: a systematic review. Stroke. 2009;40: 1082-90.
-
(2009)
Stroke
, vol.40
, pp. 1082-1090
-
-
Appelros, P.1
Stegmayr, B.2
Terent, A.3
-
3
-
-
51449096432
-
Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes
-
Reeves MJ, Bushnell CD, Howard G, Gargano JW, Duncan PW, Lynch G, Khatiwoda A, Lisabeth L. Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes. Lancet Neurol. 2008;7(10): 915-26.
-
(2008)
Lancet Neurol
, vol.7
, Issue.10
, pp. 915-926
-
-
Reeves, M.J.1
Bushnell, C.D.2
Howard, G.3
Gargano, J.W.4
Duncan, P.W.5
Lynch, G.6
Khatiwoda, A.7
Lisabeth, L.8
-
4
-
-
77957704757
-
Neuroprotection of sex steroids
-
Liu M, Kelley MH, Herson PS, Hurn PD. Neuroprotection of sex steroids. Minerva Endocrinol. 2010;35(2): 127-43.
-
(2010)
Minerva Endocrinol.
, vol.35
, Issue.2
, pp. 127-143
-
-
Liu, M.1
Kelley, M.H.2
Herson, P.S.3
Hurn, P.D.4
-
5
-
-
46949109892
-
Vascular actions of estrogens: functional implications
-
Miller VM, Duckles SP. Vascular actions of estrogens: functional implications. Pharmacol Rev. 2008;60(2): 210-41.
-
(2008)
Pharmacol Rev
, vol.60
, Issue.2
, pp. 210-241
-
-
Miller, V.M.1
Duckles, S.P.2
-
6
-
-
0016715365
-
On the relationship of brain vasculature to production of neurological deficit and morphological changes following acute unilateral common carotid artery ligation in gerbils
-
Berry K, Wiśniewski HM, Svarzbein L, Baez S. On the relationship of brain vasculature to production of neurological deficit and morphological changes following acute unilateral common carotid artery ligation in gerbils. J Neurol Sci. 1975;25(1): 75-92.
-
(1975)
J Neurol Sci
, vol.25
, Issue.1
, pp. 75-92
-
-
Berry, K.1
Wiśniewski, H.M.2
Svarzbein, L.3
Baez, S.4
-
7
-
-
0026099937
-
Sex differences in postischemic neuronal necrosis in gerbils
-
Hall ED, Pazara KE, Linseman KL. Sex differences in postischemic neuronal necrosis in gerbils. J Cereb Blood Flow Metab. 1991;11(2): 292-8.
-
(1991)
J Cereb Blood Flow Metab
, vol.11
, Issue.2
, pp. 292-298
-
-
Hall, E.D.1
Pazara, K.E.2
Linseman, K.L.3
-
8
-
-
0031984050
-
Gender-linked brain injury in experimental stroke
-
Alkayed NJ, Harukuni I, Kimes AS, London ED, Traystman RJ, Hurn PD. Gender-linked brain injury in experimental stroke. Stroke. 1998;29: 159-66.
-
(1998)
Stroke
, vol.29
, pp. 159-166
-
-
Alkayed, N.J.1
Harukuni, I.2
Kimes, A.S.3
London, E.D.4
Traystman, R.J.5
Hurn, P.D.6
-
9
-
-
0018857823
-
Distribution and properties of a mammalian soluble epoxide hydrase
-
Gill SS, Hammock BD. Distribution and properties of a mammalian soluble epoxide hydrase. Biochem Pharmacol. 1980;29(3): 389-95.
-
(1980)
Biochem Pharmacol
, vol.29
, Issue.3
, pp. 389-395
-
-
Gill, S.S.1
Hammock, B.D.2
-
10
-
-
33845347545
-
Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)
-
Inceoglu B, Schmelzer KR, Morisseau C, Jinks SL, Hammock BD. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs). Prostaglandins Other Lipid Mediat. 2007;82(1-4): 42-9.
-
(2007)
Prostaglandins Other Lipid Mediat
, vol.82
, Issue.1-4
, pp. 42-49
-
-
Inceoglu, B.1
Schmelzer, K.R.2
Morisseau, C.3
Jinks, S.L.4
Hammock, B.D.5
-
11
-
-
0035965327
-
Epoxygenase pathways of arachidonic acid metabolism
-
Zeldin DC. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem. 2001;276(39): 36059-62.
-
(2001)
J Biol Chem
, vol.276
, Issue.39
, pp. 36059-36062
-
-
Zeldin, D.C.1
-
12
-
-
0035805539
-
Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition
-
Fang X, Kaduce TL, Weintraub NL, Harmon S, Teesch LM, Morisseau C, Thompson DA, Hammock BD, Spector AA. Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition. J Biol Chem. 2001;276(18): 14867-74.
-
(2001)
J Biol Chem
, vol.276
, Issue.18
, pp. 14867-14874
-
-
Fang, X.1
Kaduce, T.L.2
Weintraub, N.L.3
Harmon, S.4
Teesch, L.M.5
Morisseau, C.6
Thompson, D.A.7
Hammock, B.D.8
Spector, A.A.9
-
13
-
-
77952889496
-
Epoxyeicosatrienoic acids and endothelium-dependent responses
-
Campbell WB, Fleming I. Epoxyeicosatrienoic acids and endothelium-dependent responses. Pflugers Arch. 2010;459(6): 881-95.
-
(2010)
Pflugers Arch.
, vol.459
, Issue.6
, pp. 881-895
-
-
Campbell, W.B.1
Fleming, I.2
-
14
-
-
33845346159
-
Epoxyeicosatrienoic acids, cell signaling and angiogenesis
-
Fleming I. Epoxyeicosatrienoic acids, cell signaling and angiogenesis. Prostaglandins Other Lipid Mediat. 2007;82(1-4): 60-7.
-
(2007)
Prostaglandins Other Lipid Mediat.
, vol.82
, Issue.1-4
, pp. 60-67
-
-
Fleming, I.1
-
15
-
-
34548495819
-
DiscrEET regulators of homeostasis: epoxyeicosatrienoic acids, cytochrome P450 epoxygenases and vascular inflammation
-
Fleming I. DiscrEET regulators of homeostasis: epoxyeicosatrienoic acids, cytochrome P450 epoxygenases and vascular inflammation. Trends Pharmacol Sci. 2007;28(9): 448-52.
-
(2007)
Trends Pharmacol Sci
, vol.28
, Issue.9
, pp. 448-452
-
-
Fleming, I.1
-
17
-
-
0026584785
-
Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid
-
Amruthesh SC, Falck JR, Ellis EF. Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid. J Neurochem. 1992;58(2): 503-10.
-
(1992)
J Neurochem
, vol.58
, Issue.2
, pp. 503-510
-
-
Amruthesh, S.C.1
Falck, J.R.2
Ellis, E.F.3
-
18
-
-
0025133442
-
Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid
-
Ellis EF, Police RJ, Yancey L, McKinney JS, Amruthesh SC. Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid. Am J Physiol. 1990;259(4 Pt 2): H1171-7.
-
(1990)
Am J Physiol
, vol.259
, Issue.4 Pt 2
-
-
Ellis, E.F.1
Police, R.J.2
Yancey, L.3
McKinney, J.S.4
Amruthesh, S.C.5
-
19
-
-
79957544946
-
Endothelium-derived hyperpolarizing factor in the brain: influence of sex, vessel size and disease state
-
Davis CM, Siler DA, Alkayed NJ. Endothelium-derived hyperpolarizing factor in the brain: influence of sex, vessel size and disease state. Womens Health (Lond Engl). 2011;7(3): 293-303.
-
(2011)
Womens Health (Lond Engl).
, vol.7
, Issue.3
, pp. 293-303
-
-
Davis, C.M.1
Siler, D.A.2
Alkayed, N.J.3
-
20
-
-
0036277938
-
Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack
-
Alkayed NJ, Goyagi T, Joh HD, Klaus J, Harder DR, Traystman RJ, Hurn PD. Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack. Stroke. 2002;33(6): 1677-84.
-
(2002)
Stroke
, vol.33
, Issue.6
, pp. 1677-1684
-
-
Alkayed, N.J.1
Goyagi, T.2
Joh, H.D.3
Klaus, J.4
Harder, D.R.5
Traystman, R.J.6
Hurn, P.D.7
-
21
-
-
33746829910
-
Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury
-
Nithipatikom K, Moore JM, Isbell MA, Falck JR, Gross GJ. Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury. Am J Physiol Heart Circ Physiol. 2006;291(2): H537-42.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
, Issue.2
-
-
Nithipatikom, K.1
Moore, J.M.2
Isbell, M.A.3
Falck, J.R.4
Gross, G.J.5
-
22
-
-
33746790148
-
Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature
-
Dhanasekaran A, Al-Saghir R, Lopez B, Zhu D, Gutterman DD, Jacobs ER, Medhora M. Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. Am J Physiol Heart Circ Physiol. 2006;291(2): H517-31.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
, Issue.2
-
-
Dhanasekaran, A.1
Al-Saghir, R.2
Lopez, B.3
Zhu, D.4
Gutterman, D.D.5
Jacobs, E.R.6
Medhora, M.7
-
23
-
-
24344464401
-
Cytochrome P450 and arachidonic acid metabolites: role in myocardial ischemia/reperfusion injury revisited
-
Gross GJ, Falck JR, Gross ER, Isbell M, Moore J, Nithipatikom K. Cytochrome P450 and arachidonic acid metabolites: role in myocardial ischemia/reperfusion injury revisited. Cardiovasc Res. 2005;68(1): 18-25.
-
(2005)
Cardiovasc Res
, vol.68
, Issue.1
, pp. 18-25
-
-
Gross, G.J.1
Falck, J.R.2
Gross, E.R.3
Isbell, M.4
Moore, J.5
Nithipatikom, K.6
-
24
-
-
33845313333
-
Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids
-
Medhora M, Dhanasekaran A, Gruenloh SK, Dunn LK, Gabrilovich M, Falck JR, Harder DR, Jacobs ER, Pratt PF. Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids. Prostaglandins Other Lipid Mediat. 2007;82(1-4): 19-29.
-
(2007)
Prostaglandins Other Lipid Mediat.
, vol.82
, Issue.1-4
, pp. 19-29
-
-
Medhora, M.1
Dhanasekaran, A.2
Gruenloh, S.K.3
Dunn, L.K.4
Gabrilovich, M.5
Falck, J.R.6
Harder, D.R.7
Jacobs, E.R.8
Pratt, P.F.9
-
25
-
-
23044439770
-
Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes
-
Liu M, Alkayed NJ. Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes. J Cereb Blood Flow Metab. 2005;25(8): 939-48.
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, Issue.8
, pp. 939-948
-
-
Liu, M.1
Alkayed, N.J.2
-
26
-
-
43949116261
-
Distribution and expression of soluble epoxide hydrolase in human brain
-
Sura P, Sura R, Enayetallah AE, Grant DF. Distribution and expression of soluble epoxide hydrolase in human brain. J Histochem Cytochem. 2008;56(6): 551-9.
-
(2008)
J Histochem Cytochem
, vol.56
, Issue.6
, pp. 551-559
-
-
Sura, P.1
Sura, R.2
Enayetallah, A.E.3
Grant, D.F.4
-
27
-
-
1842430562
-
Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues
-
Enayetallah AE, French RA, Thibodeau MS, Grant DF. Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues. J Histochem Cytochem. 2004;52(4): 447-54.
-
(2004)
J Histochem Cytochem
, vol.52
, Issue.4
, pp. 447-454
-
-
Enayetallah, A.E.1
French, R.A.2
Thibodeau, M.S.3
Grant, D.F.4
-
28
-
-
34347396963
-
A novel role for P450 eicosanoids in the neurogenic control of cerebral blood flow in the rat
-
Iliff JJ, Close LN, Selden NR, Alkayed NJ. A novel role for P450 eicosanoids in the neurogenic control of cerebral blood flow in the rat. Exp Physiol. 2007;92(4): 653-8.
-
(2007)
Exp Physiol
, vol.92
, Issue.4
, pp. 653-658
-
-
Iliff, J.J.1
Close, L.N.2
Selden, N.R.3
Alkayed, N.J.4
-
29
-
-
34347407952
-
Soluble epoxide hydrolase: a novel therapeutic target in stroke
-
Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. Soluble epoxide hydrolase: a novel therapeutic target in stroke. J Cereb Blood Flow Metab. 2007;27(12): 1931-40.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, Issue.12
, pp. 1931-1940
-
-
Zhang, W.1
Koerner, I.P.2
Noppens, R.3
Grafe, M.4
Tsai, H.J.5
Morisseau, C.6
Luria, A.7
Hammock, B.D.8
Falck, J.R.9
Alkayed, N.J.10
-
30
-
-
34247525219
-
Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury
-
Koerner IP, Jacks R, DeBarber AE, Koop D, Mao P, Grant DF, Alkayed NJ. Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury. J Neurosci. 2007;27(17): 4642-9.
-
(2007)
J Neurosci
, vol.27
, Issue.17
, pp. 4642-4649
-
-
Koerner, I.P.1
Jacks, R.2
DeBarber, A.E.3
Koop, D.4
Mao, P.5
Grant, D.F.6
Alkayed, N.J.7
-
31
-
-
69249221377
-
Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism
-
Marowsky A, Burgener J, Falck JR, Fritschy JM, Arand M. Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism. Neuroscience. 2009;163(2): 646-61.
-
(2009)
Neuroscience
, vol.163
, Issue.2
, pp. 646-661
-
-
Marowsky, A.1
Burgener, J.2
Falck, J.R.3
Fritschy, J.M.4
Arand, M.5
-
32
-
-
0030878472
-
Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids
-
Weintraub NL, Fang X, Kaduce TL, VanRollins M, Chatterjee P, Spector AA. Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids. Circ Res. 1997;81(2): 258-67.
-
(1997)
Circ Res
, vol.81
, Issue.2
, pp. 258-267
-
-
Weintraub, N.L.1
Fang, X.2
Kaduce, T.L.3
VanRollins, M.4
Chatterjee, P.5
Spector, A.A.6
-
33
-
-
0032735546
-
Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids
-
Weintraub NL, Fang X, Kaduce TL, VanRollins M, Chatterjee P, Spector AA. Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids. Am J Physiol. 1999;277(5 Pt 2): H2098-108.
-
(1999)
Am J Physiol
, vol.277
, Issue.5 Pt 2
-
-
Weintraub, N.L.1
Fang, X.2
Kaduce, T.L.3
VanRollins, M.4
Chatterjee, P.5
Spector, A.A.6
-
34
-
-
0034711488
-
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids
-
Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res. 2000;87(11): 992-8.
-
(2000)
Circ Res
, vol.87
, Issue.11
, pp. 992-998
-
-
Yu, Z.1
Xu, F.2
Huse, L.M.3
Morisseau, C.4
Draper, A.J.5
Newman, J.W.6
Parker, C.7
Graham, L.8
Engler, M.M.9
Hammock, B.D.10
Zeldin, D.C.11
Kroetz, D.L.12
-
35
-
-
33747422507
-
Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function
-
Seubert JM, Sinal CJ, Graves J, DeGraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res. 2006;99(4): 442-50.
-
(2006)
Circ Res
, vol.99
, Issue.4
, pp. 442-450
-
-
Seubert, J.M.1
Sinal, C.J.2
Graves, J.3
DeGraff, L.M.4
Bradbury, J.A.5
Lee, C.R.6
Goralski, K.7
Carey, M.A.8
Luria, A.9
Newman, J.W.10
Hammock, B.D.11
Falck, J.R.12
Roberts, H.13
Rockman, H.A.14
Murphy, E.15
Zeldin, D.C.16
-
36
-
-
57049115027
-
Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo
-
Motoki A, Merkel MJ, Packwood WH, Cao Z, Liu L, Iliff J, Alkayed NJ, van Winkle DM. Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo. Am J Physiol Heart Circ Physiol. 2008;295(5): H2128-34.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, Issue.5
-
-
Motoki, A.1
Merkel, M.J.2
Packwood, W.H.3
Cao, Z.4
Liu, L.5
Iliff, J.6
Alkayed, N.J.7
van Winkle, D.M.8
-
37
-
-
47649121828
-
Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia
-
Zhang W, Otsuka T, Sugo N, Ardeshiri A, Alhadid YK, Iliff JJ, DeBarber AE, Koop DR, Alkayed NJ. Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia. Stroke. 2008;39(7): 2073-8.
-
(2008)
Stroke
, vol.39
, Issue.7
, pp. 2073-2078
-
-
Zhang, W.1
Otsuka, T.2
Sugo, N.3
Ardeshiri, A.4
Alhadid, Y.K.5
Iliff, J.J.6
DeBarber, A.E.7
Koop, D.R.8
Alkayed, N.J.9
-
38
-
-
34047272821
-
Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice
-
Luria A, Weldon SM, Kabcenell AK, Ingraham RH, Matera D, Jiang H, Gill R, Morisseau C, Newman JW, Hammock BD. Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. J Biol Chem. 2007;282(5): 2891-8.
-
(2007)
J Biol Chem
, vol.282
, Issue.5
, pp. 2891-2898
-
-
Luria, A.1
Weldon, S.M.2
Kabcenell, A.K.3
Ingraham, R.H.4
Matera, D.5
Jiang, H.6
Gill, R.7
Morisseau, C.8
Newman, J.W.9
Hammock, B.D.10
-
39
-
-
67049119782
-
Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection
-
Simpkins AN, Rudic RD, Schreihofer DA, Roy S, Manhiani M, Tsai HJ, Hammock BD, Imig JD. Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. Am J Pathol. 2009;174(6): 2086-95.
-
(2009)
Am J Pathol
, vol.174
, Issue.6
, pp. 2086-2095
-
-
Simpkins, A.N.1
Rudic, R.D.2
Schreihofer, D.A.3
Roy, S.4
Manhiani, M.5
Tsai, H.J.6
Hammock, B.D.7
Imig, J.D.8
-
40
-
-
26444506849
-
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke
-
Fornage M, Lee CR, Doris PA, Bray MS, Heiss G, Zeldin DC, Boerwinkle E. The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet. 2005;14(19): 2829-37.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.19
, pp. 2829-2837
-
-
Fornage, M.1
Lee, C.R.2
Doris, P.A.3
Bray, M.S.4
Heiss, G.5
Zeldin, D.C.6
Boerwinkle, E.7
-
41
-
-
44449110695
-
Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans
-
Gschwendtner A, Ripke S, Freilinger T, Lichtner P, Müller-Myhsok B, Wichmann HE, Meitinger T, Dichgans M. Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans. Stroke. 2008;39(5): 1593-6.
-
(2008)
Stroke
, vol.39
, Issue.5
, pp. 1593-1596
-
-
Gschwendtner, A.1
Ripke, S.2
Freilinger, T.3
Lichtner, P.4
Müller-Myhsok, B.5
Wichmann, H.E.6
Meitinger, T.7
Dichgans, M.8
-
42
-
-
38549145416
-
Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population
-
Zhang L, Ding H, Yan J, Hui R, Wang W, Kissling GE, Zeldin DC, Wang DW. Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population. Pharmacogenet Genomics. 2008;18(1): 45-51.
-
(2008)
Pharmacogenet Genomics.
, vol.18
, Issue.1
, pp. 45-51
-
-
Zhang, L.1
Ding, H.2
Yan, J.3
Hui, R.4
Wang, W.5
Kissling, G.E.6
Zeldin, D.C.7
Wang, D.W.8
-
43
-
-
67149084404
-
Soluble epoxide hydrolase inhibition: targeting multiple mechanisms of ischemic brain injury with a single agent
-
Iliff JJ, Alkayed NJ. Soluble epoxide hydrolase inhibition: targeting multiple mechanisms of ischemic brain injury with a single agent. Future Neurol. 2009;4(2): 179-99.
-
(2009)
Future Neurol.
, vol.4
, Issue.2
, pp. 179-199
-
-
Iliff, J.J.1
Alkayed, N.J.2
-
44
-
-
79957465978
-
Soluble epoxide hydrolase: a promising therapeutic target for cardiovascular diseases
-
Ni GH, Chen JF, Chen XP, Yang TL. Soluble epoxide hydrolase: a promising therapeutic target for cardiovascular diseases. Pharmazie. 2011;66(3): 153-7.
-
(2011)
Pharmazie
, vol.66
, Issue.3
, pp. 153-157
-
-
Ni, G.H.1
Chen, J.F.2
Chen, X.P.3
Yang, T.L.4
-
45
-
-
15844391135
-
Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells
-
VanRollins M, Kaduce TL, Fang X, Knapp HR, Spector AA. Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells. J Biol Chem. 1996;271(24): 14001-9.
-
(1996)
J Biol Chem
, vol.271
, Issue.24
, pp. 14001-14009
-
-
VanRollins, M.1
Kaduce, T.L.2
Fang, X.3
Knapp, H.R.4
Spector, A.A.5
-
46
-
-
78951491442
-
Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension
-
Zhang LN, Vincelette J, Chen D, Gless RD, Anandan SK, Rubanyi GM, Webb HK, MacIntyre DE, Wang YX. Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension. Eur J Pharmacol. 2011;654(1): 68-74.
-
(2011)
Eur J Pharmacol
, vol.654
, Issue.1
, pp. 68-74
-
-
Zhang, L.N.1
Vincelette, J.2
Chen, D.3
Gless, R.D.4
Anandan, S.K.5
Rubanyi, G.M.6
Webb, H.K.7
MacIntyre, D.E.8
Wang, Y.X.9
-
47
-
-
0023609441
-
Hepatic biotransformation in lean and obese Wistar Kyoto rats: comparison to that in streptozotocin-pretreated Sprague-Dawley rats
-
Watkins 3rd JB, Mangels LA. Hepatic biotransformation in lean and obese Wistar Kyoto rats: comparison to that in streptozotocin-pretreated Sprague-Dawley rats. Comp Biochem Physiol C. 1987;88(1): 159-64.
-
(1987)
Comp Biochem Physiol C.
, vol.88
, Issue.1
, pp. 159-164
-
-
Watkins 3rd, J.B.1
Mangels, L.A.2
-
48
-
-
19944424115
-
Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats
-
Zhao X, Dey A, Romanko OP, Stepp DW, Wang MH, Zhou Y, Jin L, Pollock JS, Webb RC, Imig JD. Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats. Am J Physiol Regul Integr Comp Physiol. 2005;288(1): R188-96.
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.288
, Issue.1
-
-
Zhao, X.1
Dey, A.2
Romanko, O.P.3
Stepp, D.W.4
Wang, M.H.5
Zhou, Y.6
Jin, L.7
Pollock, J.S.8
Webb, R.C.9
Imig, J.D.10
-
49
-
-
33744940507
-
PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats
-
Zhao X, Quigley JE, Yuan J, Wang MH, Zhou Y, Imig JD. PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats. Am J Physiol Heart Circ Physiol. 2006;290(6): H2187-95.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, Issue.6
-
-
Zhao, X.1
Quigley, J.E.2
Yuan, J.3
Wang, M.H.4
Zhou, Y.5
Imig, J.D.6
-
50
-
-
0034704156
-
Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation
-
Sinal CJ, Miyata M, Tohkin M, Nagata K, Bend JR, Gonzalez FJ. Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation. J Biol Chem. 2000;275(51): 40504-10.
-
(2000)
J Biol Chem
, vol.275
, Issue.51
, pp. 40504-40510
-
-
Sinal, C.J.1
Miyata, M.2
Tohkin, M.3
Nagata, K.4
Bend, J.R.5
Gonzalez, F.J.6
-
51
-
-
0344824685
-
Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
-
Chanas B, Wang H, Ghanayem BI. Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases. Toxicol Appl Pharmacol. 2003;193(2): 293-302.
-
(2003)
Toxicol Appl Pharmacol
, vol.193
, Issue.2
, pp. 293-302
-
-
Chanas, B.1
Wang, H.2
Ghanayem, B.I.3
-
52
-
-
68249087936
-
Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia
-
Zhang W, Iliff JJ, Campbell CJ, Wang RK, Hurn PD, Alkayed NJ. Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia. J Cereb Blood Flow Metab. 2009;29(8): 1475-81.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, Issue.8
, pp. 1475-1481
-
-
Zhang, W.1
Iliff, J.J.2
Campbell, C.J.3
Wang, R.K.4
Hurn, P.D.5
Alkayed, N.J.6
-
53
-
-
84863992246
-
Mechanism of the sex difference in neuronal ischemic cell death
-
Fairbanks SL, Young JM, Nelson JW, Davis CM, Koerner IP, Alkayed NJ. Mechanism of the sex difference in neuronal ischemic cell death. Neuroscience. 2012;219: 183-91.
-
(2012)
Neuroscience
, vol.219
, pp. 183-191
-
-
Fairbanks, S.L.1
Young, J.M.2
Nelson, J.W.3
Davis, C.M.4
Koerner, I.P.5
Alkayed, N.J.6
-
54
-
-
38449090444
-
Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia
-
Koerner IP, Zhang W, Cheng J, Parker S, Hurn PD, Alkayed NJ. Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia. Front Biosci. 2008;13: 2833-41.
-
(2008)
Front Biosci
, vol.13
, pp. 2833-2841
-
-
Koerner, I.P.1
Zhang, W.2
Cheng, J.3
Parker, S.4
Hurn, P.D.5
Alkayed, N.J.6
-
55
-
-
84864287693
-
Soluble epoxide hydrolase: sex differences and role in endothelial cell survival
-
Gupta NC, Davis CM, Nelson JW, Young JM, Alkayed NJ. Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. ATVB. 2012;32(8): 1936-42.
-
(2012)
ATVB.
, vol.32
, Issue.8
, pp. 1936-1942
-
-
Gupta, N.C.1
Davis, C.M.2
Nelson, J.W.3
Young, J.M.4
Alkayed, N.J.5
-
56
-
-
80053919098
-
Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart
-
Edin ML, Wang Z, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Foley JF, Torphy R, Ronnekleiv OK, Tomer KB, Lee CR, Zeldin DC. Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J. 2011;25(10): 3436-47.
-
(2011)
FASEB J
, vol.25
, Issue.10
, pp. 3436-3447
-
-
Edin, M.L.1
Wang, Z.2
Bradbury, J.A.3
Graves, J.P.4
Lih, F.B.5
DeGraff, L.M.6
Foley, J.F.7
Torphy, R.8
Ronnekleiv, O.K.9
Tomer, K.B.10
Lee, C.R.11
Zeldin, D.C.12
-
57
-
-
0034923447
-
Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells
-
Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK, Zeldin DC. Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol. 2001;60(2): 310-20.
-
(2001)
Mol Pharmacol
, vol.60
, Issue.2
, pp. 310-320
-
-
Yang, B.1
Graham, L.2
Dikalov, S.3
Mason, R.P.4
Falck, J.R.5
Liao, J.K.6
Zeldin, D.C.7
-
58
-
-
0034046443
-
Investigation of estrogen status and increased stroke sensitivity on cerebral blood flow after a focal ischemic insult
-
Carswell HV, Anderson NH, Morton JJ, McCulloch J, Dominiczak AF, Macrae IM. Investigation of estrogen status and increased stroke sensitivity on cerebral blood flow after a focal ischemic insult. J Cereb Blood Flow Metab. 2000;20(6): 931-6.
-
(2000)
J Cereb Blood Flow Metab.
, vol.20
, Issue.6
, pp. 931-936
-
-
Carswell, H.V.1
Anderson, N.H.2
Morton, J.J.3
McCulloch, J.4
Dominiczak, A.F.5
Macrae, I.M.6
-
59
-
-
0035478068
-
Estrogen and Bcl-2: gene induction and effect of transgene in experimental stroke
-
Alkayed NJ, Goto S, Sugo N, Joh HD, Klaus J, Crain BJ, Bernard O, Traystman RJ, Hurn PD. Estrogen and Bcl-2: gene induction and effect of transgene in experimental stroke. J Neurosci. 2001;21(19): 7543-50.
-
(2001)
J Neurosci.
, vol.21
, Issue.19
, pp. 7543-7550
-
-
Alkayed, N.J.1
Goto, S.2
Sugo, N.3
Joh, H.D.4
Klaus, J.5
Crain, B.J.6
Bernard, O.7
Traystman, R.J.8
Hurn, P.D.9
-
60
-
-
0141535178
-
Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection
-
McCullough LD, Blizzard K, Simpson ER, Oz OK, Hurn PD. Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection. J Neurosci. 2003;23(25): 8701-5.
-
(2003)
J Neurosci.
, vol.23
, Issue.25
, pp. 8701-8705
-
-
McCullough, L.D.1
Blizzard, K.2
Simpson, E.R.3
Oz, O.K.4
Hurn, P.D.5
-
61
-
-
12844268496
-
Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model
-
Ardelt AA, McCullough LD, Korach KS, Wang MM, Munzenmaier DH, Hurn PD. Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model. Stroke. 2005;36(2): 337-41.
-
(2005)
Stroke.
, vol.36
, Issue.2
, pp. 337-341
-
-
Ardelt, A.A.1
McCullough, L.D.2
Korach, K.S.3
Wang, M.M.4
Munzenmaier, D.H.5
Hurn, P.D.6
-
62
-
-
17044430692
-
Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection
-
McCullough LD, Zeng Z, Blizzard KK, Debchoudhury I, Hurn PD. Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection. J Cereb Blood Flow Metab. 2005;25(4): 502-12.
-
(2005)
J Cereb Blood Flow Metab.
, vol.25
, Issue.4
, pp. 502-512
-
-
McCullough, L.D.1
Zeng, Z.2
Blizzard, K.K.3
Debchoudhury, I.4
Hurn, P.D.5
-
63
-
-
33749247599
-
Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection
-
Xu Y, Zhang W, Klaus J, Young J, Koerner I, Sheldahl LC, Hurn PD, Martínez-Murillo F, Alkayed NJ. Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection. Proc Natl Acad Sci U S A. 2006;103(39): 14489-94.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, Issue.39
, pp. 14489-14494
-
-
Xu, Y.1
Zhang, W.2
Klaus, J.3
Young, J.4
Koerner, I.5
Sheldahl, L.C.6
Hurn, P.D.7
Martínez-Murillo, F.8
Alkayed, N.J.9
-
64
-
-
33749033087
-
Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permanent middle cerebral artery occlusion
-
O'Donnell ME, Lam TI, Tran LQ, Foroutan S, Anderson SE. Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab. 2006;26(10): 1234-49.
-
(2006)
J Cereb Blood Flow Metab.
, vol.26
, Issue.10
, pp. 1234-1249
-
-
O'Donnell, M.E.1
Lam, T.I.2
Tran, L.Q.3
Foroutan, S.4
Anderson, S.E.5
-
65
-
-
33846319756
-
Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta
-
Suzuki S, Gerhold LM, Böttner M, Rau SW, Dela Cruz C, Yang E, Zhu H, Yu J, Cashion AB, Kindy MS, Merchenthaler I, Gage FH, Wise PM. Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta. J Comp Neurol. 2007;500(6): 1064-75.
-
(2007)
J Comp Neurol.
, vol.500
, Issue.6
, pp. 1064-1075
-
-
Suzuki, S.1
Gerhold, L.M.2
Böttner, M.3
Rau, S.W.4
Dela Cruz, C.5
Yang, E.6
Zhu, H.7
Yu, J.8
Cashion, A.B.9
Kindy, M.S.10
Merchenthaler, I.11
Gage, F.H.12
Wise, P.M.13
-
66
-
-
34447116951
-
Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection
-
Dziennis S, Jia T, Rønnekleiv OK, Hurn PD, Alkayed NJ. Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection. J Neurosci. 2007;27(27): 7268-74.
-
(2007)
J Neurosci.
, vol.27
, Issue.27
, pp. 7268-7274
-
-
Dziennis, S.1
Jia, T.2
Rønnekleiv, O.K.3
Hurn, P.D.4
Alkayed, N.J.5
-
67
-
-
41149167594
-
Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury
-
Brown CM, Dela Cruz CD, Yang E, Wise PM. Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury. Exp Neurol. 2008;210(2): 782-7.
-
(2008)
Exp Neurol.
, vol.210
, Issue.2
, pp. 782-787
-
-
Brown, C.M.1
Dela Cruz, C.D.2
Yang, E.3
Wise, P.M.4
-
68
-
-
84862954772
-
Effects of chronic and acute oestrogen replacement therapy in aged animals after experimental stroke
-
Liu F, Benashski SE, Xu Y, Siegel M, McCullough LD. Effects of chronic and acute oestrogen replacement therapy in aged animals after experimental stroke. J Neuroendocrinol. 2012;24(2): 319-30.
-
(2012)
J Neuroendocrinol.
, vol.24
, Issue.2
, pp. 319-330
-
-
Liu, F.1
Benashski, S.E.2
Xu, Y.3
Siegel, M.4
McCullough, L.D.5
|