Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1α-linked induction of P450 2C11 epoxygenase in astrocytes

Journal of Cerebral Blood Flow and Metabolism

Volumn 25, Issue 8, 2005, Pages 939-948

  Liu, Mingyue ^a   Alkayed, Nabil J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Arachidonic acid; Astrocytes; EET; Hypoxia preconditioning (HPC); Hypoxia inducible factor (HIF); Oxygen glucose deprivation (OGD); P450 2C11 epoxygenase; Tolerance

Indexed keywords

ARACHIDONIC ACID; ARACHIDONIC ACID EPOXYGENASE; CYTOCHROME P450 2C11; CYTOCHROME P450 2C11 EPOXYGENASE; DNA; EPOXYICOSATRIENOIC ACID; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; OXYGEN; OXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASTROCYTE; BINDING SITE; BRAIN; BRAIN HYPOXIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE; HYPOTHESIS; HYPOXIA; HYPOXIA PRECONDITIONING; NERVE CELL CULTURE; NEWBORN; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANOXIA; ARYL HYDROCARBON HYDROXYLASES; ASTROCYTES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL DEATH; CELLS, CULTURED; EICOSANOIC ACIDS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; ISCHEMIC PRECONDITIONING; NUCLEAR PROTEINS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STEROID 16-ALPHA-HYDROXYLASE; TRANSCRIPTION FACTORS;

EID: 23044439770     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600085     Document Type: Article

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