메뉴 건너뛰기




Volumn 153, Issue 6, 2012, Pages 2747-2755

Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARTIC ACID; CALCIUM; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; LEUCINE; SOMATOSTATIN 14; SOMATOSTATIN RECEPTOR 2;

EID: 84861312469     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1662     Document Type: Article
Times cited : (8)

References (53)
  • 1
    • 0014348378 scopus 로고
    • Stimulatory and inhibitory effects of purified hypothalamic extracts on growth hormone release from rat pituitary in vitro
    • Krulich L, Dhariwal AP, McCann SM 1968 Stimulatory and inhibitory effects of purified hypothalamic extracts on growth hormone release from rat pituitary in vitro. Endocrinology 83:783-790
    • (1968) Endocrinology , vol.83 , pp. 783-790
    • Krulich, L.1    Dhariwal, A.P.2    McCann, S.M.3
  • 3
    • 0029114410 scopus 로고
    • Molecular biology of somatostatin receptors
    • Reisine T, Bell GI 1995 Molecular biology of somatostatin receptors. Endocr Rev 16:427-442
    • (1995) Endocr Rev , vol.16 , pp. 427-442
    • Reisine, T.1    Bell, G.I.2
  • 4
    • 0030612281 scopus 로고    scopus 로고
    • Molecular pharmacology of somatastatin receptor subtypes
    • Patel YC 1997 Molecular pharmacology of somatostatin receptor subtypes. J Endocrinol Invest 20:348-367 (Pubitemid 27410043)
    • (1997) Journal of Endocrinological Investigation , vol.20 , Issue.6 , pp. 348-367
    • Patel, Y.C.1
  • 5
    • 0032780823 scopus 로고    scopus 로고
    • Somatostatin and its receptor family
    • DOI 10.1006/frne.1999.0183
    • Patel YC 1999 Somatostatin and its receptor family. Front Neuroendocrinol 20:157-198 (Pubitemid 29362641)
    • (1999) Frontiers in Neuroendocrinology , vol.20 , Issue.3 , pp. 157-198
    • Patel, Y.C.1
  • 7
    • 0038069184 scopus 로고    scopus 로고
    • Somatostatin analogs in the diagnosis and treatment of cancer
    • DOI 10.1016/S1043-2760(02)00667-7, PII S1043276002006677
    • Lamberts SW, de Herder WW, Hofland LJ 2002 Somatostatin analogs in the diagnosis and treatment of cancer. Trends Endocrinol Metab 13:451-457 (Pubitemid 36733940)
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , Issue.10 , pp. 451-457
    • Lamberts, S.W.J.1    De Herder, W.W.2    Hofland, L.J.3
  • 8
    • 0037323565 scopus 로고    scopus 로고
    • The pathophysiological consequences of somatostatin receptor internalization and resistance
    • DOI 10.1210/er.2000-0001
    • Hofland LJ, Lamberts SW 2003 The pathophysiological consequences of somatostatin receptor internalization and resistance. Endocr Rev 24:28-47 (Pubitemid 36223278)
    • (2003) Endocrine Reviews , vol.24 , Issue.1 , pp. 28-47
    • Hofland, L.J.1    Lamberts, S.W.J.2
  • 11
    • 0026041670 scopus 로고
    • The role of somatostatin and its analogs in the diagnosis and treatment of tumors
    • Lamberts SW, Krenning EP, Reubi JC 1991 The role of somatostatin and its analogs in the diagnosis and treatment of tumors. Endocr Rev 12:450-482
    • (1991) Endocr Rev , vol.12 , pp. 450-482
    • Lamberts, S.W.1    Krenning, E.P.2    Reubi, J.C.3
  • 12
    • 70349398761 scopus 로고    scopus 로고
    • Vapreotide in variceal bleeding
    • Patch D, BurroughsA2002 Vapreotide in variceal bleeding. J Hepatol 37:167-168
    • (2002) J Hepatol , vol.37 , pp. 167-168
    • Patch, D.1    Burroughs, A.2
  • 13
    • 0036255688 scopus 로고    scopus 로고
    • Targeted therapy of cancer with radiolabeled antibodies
    • GoldenbergDM2002 Targeted therapy of cancer with radiolabeled antibodies. J Nucl Med 43:693-713 (Pubitemid 34507123)
    • (2002) Journal of Nuclear Medicine , vol.43 , Issue.5 , pp. 693-713
    • Goldenberg, D.M.1
  • 19
    • 34247385556 scopus 로고    scopus 로고
    • Characterization of somatostatin receptor subtype 2 expression in stably transfected A-427 human cancer cells
    • DOI 10.2310/7290.2007.00001
    • Parry JJ, Eiblmaier M, Andrews R, Meyer LA, Higashikubo R, Anderson CJ, Rogers BE 2007 Characterization of somatostatin receptor subtype 2 expression in stably transfected A-427 human cancer cells. Mol Imaging 6:56-67 (Pubitemid 46642491)
    • (2007) Molecular Imaging , vol.6 , Issue.1 , pp. 56-67
    • Parry, J.J.1    Eiblmaier, M.2    Andrews, R.3    Meyer, L.A.4    Higashikubo, R.5    Anderson, C.J.6    Rogers, B.E.7
  • 21
    • 77950269180 scopus 로고    scopus 로고
    • Somatostatin and somatostatin receptors
    • Kumar U, GrantM2010 Somatostatin and somatostatin receptors. Results Probl Cell Differ 50:137-184
    • (2010) Results Probl Cell Differ , vol.50 , pp. 137-184
    • Kumar, U.1    Grant, M.2
  • 22
    • 0031617855 scopus 로고    scopus 로고
    • The elucidation of somatostatin receptor functions: A current view
    • Meyerhof W 1998 The elucidation of somatostatin receptor functions: a current view. Rev Physiol Biochem Pharmacol 133:55-108
    • (1998) Rev Physiol Biochem Pharmacol , vol.133 , pp. 55-108
    • Meyerhof, W.1
  • 23
    • 43549097557 scopus 로고    scopus 로고
    • Somatostatin/somatostatin receptor signalling: Phosphotyrosine phosphatases
    • DOI 10.1016/j.mce.2007.08.012, PII S0303720707003322
    • Florio T 2008 Somatostatin/somatostatin receptor signalling: phosphotyrosine phosphatases. Mol Cell Endocrinol 286:40-48 (Pubitemid 351680234)
    • (2008) Molecular and Cellular Endocrinology , vol.286 , Issue.1-2 , pp. 40-48
    • Florio, T.1
  • 24
    • 0027249759 scopus 로고
    • + regulation of agonist binding but does not alter receptor-G protein association
    • Kong H, Raynor K, Yasuda K, Bell GI, Reisine T 1993 Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association. Mol Pharmacol 44:380-384 (Pubitemid 23252244)
    • (1993) Molecular Pharmacology , vol.44 , Issue.2 , pp. 380-384
    • Kong, H.1    Raynor, K.2    Yasuda, K.3    Bell, G.I.4    Reisine, T.5
  • 25
    • 0028787944 scopus 로고
    • Identification of a critical aspartate residue in transmembrane domain three necessary for the binding of somatostatin to the somatostatin receptor SSTR2
    • Strnad J, Hadcock JR 1995 Identification of a critical aspartate residue in transmembrane domain three necessary for the binding of somatostatin to the somatostatin receptor SSTR2. Biochem Biophys Res Commun 216:913-921
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 913-921
    • Strnad, J.1    Hadcock, J.R.2
  • 26
    • 37649015741 scopus 로고    scopus 로고
    • Signaling can be uncoupled from imaging of the somatostatin receptor type 2
    • Han L, Yang D, Kundra V 2007 Signaling can be uncoupled from imaging of the somatostatin receptor type 2. Mol Imaging 6:427-437
    • (2007) Mol Imaging , vol.6 , pp. 427-437
    • Han, L.1    Yang, D.2    Kundra, V.3
  • 27
    • 0033047987 scopus 로고    scopus 로고
    • Agonist-independent internalization and activity of a C-terminally truncated somatostatin receptor subtype 2 (δ349)
    • DOI 10.1046/j.1471-4159.1999.0721275.x
    • Schwartkop CP, Kreienkamp HJ, Richter D 1999 Agonist-independent internalization and activity of a c-terminally truncated somatostatin receptor subtype 2 (δ349). J Neurochem 72:1275-1282 (Pubitemid 29085044)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.3 , pp. 1275-1282
    • Schwartkop, C.-P.1    Kreienkamp, H.-J.2    Richter, D.3
  • 28
    • 0027525330 scopus 로고
    • The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ in coupling efficiency to adenylate cyclase and in agonist-induced receptor desensitization
    • DOI 10.1016/0014-5793(93)80349-Y
    • Vanetti M, Vogt G, Höllt V 1993 The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ in coupling efficiency to adenylate cyclase and in agonist-induced receptor desensitization. FEBS Lett 331:260-266 (Pubitemid 23287284)
    • (1993) FEBS Letters , vol.331 , Issue.3 , pp. 260-266
    • Vanetti, M.1    Vogt, G.2    Hollt, V.3
  • 29
    • 0037264051 scopus 로고    scopus 로고
    • Non-invasive gamma camera imaging of gene transfer using an adenoviral vector encoding an epitope-tagged receptor as a reporter
    • DOI 10.1038/sj.gt.3301853
    • Rogers BE, Chaudhuri TR, Reynolds PN, Della Manna D, Zinn KR 2003 Non-invasive γ camera imaging of gene transfer using an adenoviral vector encoding an epitope tagged receptor as a reporter. Gene Ther 10:105-114 (Pubitemid 36582582)
    • (2003) Gene Therapy , vol.10 , Issue.2 , pp. 105-114
    • Rogers, B.E.1    Chaudhuri, T.R.2    Reynolds, P.N.3    Della, M.D.4    Zinn, K.R.5
  • 30
    • 0036189211 scopus 로고    scopus 로고
    • Noninvasive monitoring of somatostatin receptor type 2 chimeric gene transfer
    • Kundra V, Mannting F, Jones AG, Kassis AI 2002 Noninvasive monitoring of somatostatin receptor subtype 2 chimeric gene transfer. J Nucl Med 43:406-412 (Pubitemid 34208104)
    • (2002) Journal of Nuclear Medicine , vol.43 , Issue.3 , pp. 406-412
    • Kundra, V.1    Mannting, F.2    Jones, A.G.3    Kassis, A.I.4
  • 32
    • 0030813044 scopus 로고    scopus 로고
    • The tyrosine phosphatase SHP-1 associates with the sst2 somatostatin receptor and is an essential component of sst2-mediated inhibitory growth signaling
    • DOI 10.1074/jbc.272.39.24448
    • Lopez F, Estève JP, Buscail L, Delesque N, Saint-Laurent N, Théveniau M, Nahmias C, Vaysse N, Susini C 1997 The tyrosine phosphatase SHP-1 associates with the sst2 somatostatin receptor and is an essential component of sst2-mediated inhibitory growth signaling. J Biol Chem 272:24448-24454 (Pubitemid 27418653)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.39 , pp. 24448-24454
    • Lopez, F.1    Esteve, J.-P.2    Buscail, L.3    Delesque, N.4    Saint-Laurent, N.5    Theveniau, M.6    Nahmias, C.7    Vaysse, N.8    Susini, C.9
  • 33
    • 0038757751 scopus 로고    scopus 로고
    • Inhibitory role of the somatostatin receptor SST2 on the intracrine-regulated cell proliferation induced by the 210-amino acid fibroblast growth factor-2 isoform. Implication of JAK2
    • DOI 10.1074/jbc.M210767200
    • Hortala M, Ferjoux G, Estival A, Bertrand C, Schulz S, Pradayrol L, Susini C, Clemente F 2003 Inhibitory role of the somatostatin receptor SST2 on the intracrine-regulated cell proliferation induced by the 210-amino acid fibroblast growth factor-2 isoform. J Biol Chem 278:20574-20581 (Pubitemid 36806355)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.23 , pp. 20574-20581
    • Hortala, M.1    Ferjoux, G.2    Estival, A.3    Bertrand, C.4    Schulz, S.5    Pradayrol, L.6    Susini, C.7    Clemente, F.8
  • 34
    • 4344571483 scopus 로고    scopus 로고
    • Agonist-dependent dissociation of human somatostatin receptor 2 dimers: A role in receptor trafficking
    • DOI 10.1074/jbc.M407310200
    • Grant M, Collier B, KumarU2004 Agonist-dependent dissociation of human somatostatin receptor 2 dimers. J Biol Chem 279:36179-36183 (Pubitemid 39128952)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.35 , pp. 36179-36183
    • Grant, M.1    Collier, B.2    Kumar, U.3
  • 37
    • 52949103344 scopus 로고    scopus 로고
    • Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization
    • Grant M, Alturaihi H, Jaquet P, Collier B, Kumar U 2008 cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization. Mol Endocrinol 22:2278-2292
    • (2008) Mol Endocrinol , vol.22 , pp. 2278-2292
    • Grant, M.1    Alturaihi, H.2    Jaquet, P.3    Collier, B.4    Kumar, U.5
  • 39
    • 0034772465 scopus 로고    scopus 로고
    • Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction
    • DOI 10.1038/sj.gt.3301542
    • Liang Q, Satyamurthy N, Barrio JR, Toyokuni T, Phelps MP, Gambhir SS, Herschman HR 2001 Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction. Gene Ther 8:1490-1498 (Pubitemid 32994660)
    • (2001) Gene Therapy , vol.8 , Issue.19 , pp. 1490-1498
    • Liang, Q.1    Satyamurthy, N.2    Barrio, J.R.3    Toyokuni, T.4    Phelps, M.P.5    Gambhir, S.S.6    Herschman, H.R.7
  • 40
    • 0037163091 scopus 로고    scopus 로고
    • β-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif
    • DOI 10.1074/jbc.M204033200
    • Huttenrauch F, Nitzki A, Lin FT, Höning S, Oppermann M 2002 β-Arrestin binding to CC chemokine receptor 5 requires multiple c-terminal receptor phosphorylation sites and involves a conserved asp-arg-tyr sequence motif. J Biol Chem 277:30769-30777 (Pubitemid 34970774)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.34 , pp. 30769-30777
    • Huttenrauch, F.1    Nitzki, A.2    Lin, F.-T.3    Honing, S.4    Oppermann, M.5
  • 42
    • 0042803630 scopus 로고
    • Site-directed mutagenesis of human β-adrenergic receptors: Substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase
    • Fraser CM, Chung FZ, Wang CD, Venter JC 1988 Site-directed mutagenesis of human β-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase. Proc Natl Acad Sci USA 85:5478-5482
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5478-5482
    • Fraser, C.M.1    Chung, F.Z.2    Wang, C.D.3    Venter, J.C.4
  • 43
    • 0037203302 scopus 로고    scopus 로고
    • Effects of mutations in the highly conserved DRY motif on binding affinity, expression, and G-protein recruitment of the human angiotensin II type-2 receptor
    • DOI 10.1016/S0169-328X(02)00552-1, PII S0169328X02005521
    • Moore SA, Patel AS, Huang N, Lavin BC, Grammatopoulos TN, Andres RD, Weyhenmeyer JA 2002 Effects of mutations in the highly conserved DRY motif on binding affinity, expression, and G-protein recruitment of the human angiotensin II type-2 receptor. Mol Brain Res 109:161-167 (Pubitemid 36078381)
    • (2002) Molecular Brain Research , vol.109 , Issue.1-2 , pp. 161-167
    • Moore, S.A.1    Patel, A.S.2    Huang, N.3    Lavin, B.C.4    Grammatopoulos, T.N.5    Andres, R.D.6    Weyhenmeyer, J.A.7
  • 44
    • 77149154974 scopus 로고    scopus 로고
    • Phosphorylation of theμ-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy
    • Clayton CC, Bruchas MR, Lee ML, Chavkin C 2010 Phosphorylation of theμ-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy. Mol Pharmacol 77:339-347
    • (2010) Mol Pharmacol , vol.77 , pp. 339-347
    • Clayton, C.C.1    Bruchas, M.R.2    Lee, M.L.3    Chavkin, C.4
  • 45
    • 0026006986 scopus 로고
    • Site-directed mutagenesis of α 2A-adrenergic receptors: Identification of amino acids involved in ligand binding and receptor activation by agonists
    • Wang CD, Buck MA, FraserCM1991 Site-directed mutagenesis of α 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists. Mol Pharmacol 40:168-179
    • (1991) Mol Pharmacol , vol.40 , pp. 168-179
    • Wang, C.D.1    Buck, M.A.2    Fraser, C.M.3
  • 46
    • 0028800729 scopus 로고
    • Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor
    • Elling CE, Nielsen SM, Schwartz TW 1995 Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor. Nature 374:74-77
    • (1995) Nature , vol.374 , pp. 74-77
    • Elling, C.E.1    Nielsen, S.M.2    Schwartz, T.W.3
  • 47
    • 0024847889 scopus 로고
    • 1 muscarinic acetylcholine receptors: Conserved aspartic acids play important roles in receptor function
    • Fraser CM, Wang CD, Robinson DA, Gocayne JD, Venter JC 1989 Site-directed mutagenesis of m1 muscarinic acetylcholine receptors: conserved aspartic acids play important roles in receptor function. Mol Pharmacol 36:840-847 (Pubitemid 20019555)
    • (1989) Molecular Pharmacology , vol.36 , Issue.6 , pp. 840-847
    • Fraser, C.M.1    Wang, C.-D.2    Robinson, D.A.3    Gocayne, J.D.4    Graig, V.J.5
  • 48
    • 0029081150 scopus 로고
    • Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor
    • Arora KK, Sakai A, Catt KJ 1995 Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin- releasing hormone receptor. J Biol Chem 270:22820-22826
    • (1995) J Biol Chem , vol.270 , pp. 22820-22826
    • Arora, K.K.1    Sakai, A.2    Catt, K.J.3
  • 49
    • 0032492650 scopus 로고    scopus 로고
    • Rhodopsin arginine-135 mutants are phosphorylated by rhodopsin kinase and bind arrestin in the absence of 11-cis-retinal
    • DOI 10.1021/bi9731100
    • Shi W, Sports CD, Raman D, Shirakawa S, Osawa S, Weiss ER 1998 Rhodopsin arginine-135 mutants are phosphorylated by rhodopsin kinase and bind arrestin in the absence of 11-cis-retinal. Biochemistry 37:4869-4874 (Pubitemid 28175968)
    • (1998) Biochemistry , vol.37 , Issue.14 , pp. 4869-4874
    • Shi, W.1    Sports, C.D.2    Raman, D.3    Shirakawa, S.4    Osawa, S.5    Weiss, E.R.6
  • 51
    • 0034730097 scopus 로고    scopus 로고
    • Transducin-dependent protonation of glutamic acid 134 in rhodopsin
    • DOI 10.1021/bi000912d
    • Fahmy K, Sakmar TP, Siebert F 2000 Transducin-dependent protonation of glutamic acid 134 in rhodopsin. Biochemistry 39: 10607-10612 (Pubitemid 30655939)
    • (2000) Biochemistry , vol.39 , Issue.34 , pp. 10607-10612
    • Fahmy, K.1    Sakmar, T.P.2    Siebert, F.3
  • 52
    • 85047680874 scopus 로고    scopus 로고
    • + current in human growth hormone-secreting adenoma cells
    • DOI 10.1210/en.138.6.2405
    • Takano K, Yasufuku-Takano J, Teramoto A, Fujita T 1997 Gi3 mediates somatostatin-induced activation of an inwardly rectifying K+ current in human growth hormone-secreting adenoma cells. Endocrinology 138:2405-2409 (Pubitemid 27215243)
    • (1997) Endocrinology , vol.138 , Issue.6 , pp. 2405-2409
    • Takano, K.1    Yasufuku-Takano, J.2    Teramoto, A.3    Fujita, T.4
  • 53
    • 0024578585 scopus 로고
    • Somatostatin blocks a calcium current in rat sympathetic ganglion neurones
    • Ikeda SR, SchofieldGG1989 Somatostatin blocks a calcium current in rat sympathetic ganglion neurons. J Physiol 409:221-240 (Pubitemid 19052981)
    • (1989) Journal of Physiology , vol.409 , pp. 221-240
    • Ikeda, S.R.1    Schofield, G.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.