Binding of anti-ssa antibodies to apoptotic fetal cardiocytes stimulates urokinase plasminogen activator (uPA)/uPA receptor-dependent activation of TGF-β and potentiates fibrosis

Journal of Immunology

Volumn 187, Issue 10, 2011, Pages 5392-5401

  Briassouli, Paraskevi ^a   Rifkin, Daniel ^a   Clancy, Robert M ^a   Buyon, Jill P ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; IMMUNOGLOBULIN G; RO ANTIBODY; SMAD2 PROTEIN; SMOOTH MUSCLE ACTIN; TRANSFORMING GROWTH FACTOR BETA; UROKINASE RECEPTOR;

ANTIGEN BINDING; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL TRANSDIFFERENTIATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; FIBROBLAST; FIBROSIS; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MYOFIBROBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

APOPTOSIS; AUTOANTIBODIES; BINDING SITES, ANTIBODY; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; CICATRIX; COCULTURE TECHNIQUES; FEMALE; FETAL HEART; FIBROSIS; HUMANS; MYOCYTES, CARDIAC; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; RIBONUCLEOPROTEINS; TRANSFORMING GROWTH FACTOR BETA; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 81455135807     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101288     Document Type: Article

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