Safrole oxide induces human umbilical vein endothelial cell transdifferentiation to 5-hydroxytryptaminergic neuron-like cells through tropomyosin receptor kinase A/cyclooxygenase 2/nuclear factor-kappa B/interleukin 8 signaling

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 10, 2011, Pages 1512-1522

  Su, Le ^a,b   Zhao, Jing ^a,b   Zhao, Bao Xiang ^a   Zhang, Shang Li ^a,b   Miao, Jun Ying ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

5 Hydroxytryptaminergic neuron like cells; Apoptosis; Endothelial neural transdifferentiation; Human umbilical vein endothelial cell; Safrole oxide

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; REACTIVE OXYGEN METABOLITE; SAFROLE; SHORT HAIRPIN RNA; TROPOMYOSIN; TROPOMYOSIN RECEPTOR KINASE A; UNCLASSIFIED DRUG;

5 HYDROXYTRYPTAMINERGIC NEURON LIKE CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL TRANSDIFFERENTIATION; DOWNSTREAM PROCESSING; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; REGULATORY MECHANISM; SEROTONINERGIC NERVE CELL; UMBILICAL VEIN ENDOTHELIAL CELL;

APOPTOSIS; CALCIUM; CELL SURVIVAL; CELL TRANSDIFFERENTIATION; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-8; METABOLIC NETWORKS AND PATHWAYS; NEURONS; NF-KAPPA B; PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SAFROLE; SEROTONIN; TROPOMYOSIN; UMBILICAL VEINS;

EID: 80052265745     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.07.002     Document Type: Article

References (40)

1. D.B. Arthur, K. Akassoglou, and P.A. Insel P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation Proc. Natl. Acad. Sci. U. S. A. 102 2005 19138 19143 (Pubitemid 43049579)
2. S. Bhattacharyya, P.K. Dudeja, and J.K. Tobacman R.O.S. Hsp27, and IKKbeta mediate dextran sodium sulfate (DSS) activation of IkappaBa, NFkappaB, and IL-8 Inflamm. Bowel Dis. 15 2009 673 683
3. G. Cantarella, L. Lempereur, M. Presta, D. Ribatti, G. Lombardo, P. Lazarovici, G. Zappal, C. Pafumi, and R. Bernardini Nerve growth factor-endothelial cell interaction leads to angiogenesis in vitro and in vivo FASEB J. 16 2002 1307 1309
4. V. Caretti, D. Stoffers, A. Winogrodzka, I.U. Isaias, G. Costantino, G. Pezzoli, C. Ferrarese, A. Antonini, E.C. Wolters, and J. Booij Loss of thalamic serotonin transporters in early drug-naïve Parkinson's disease patients is associated with tremor: an [(123)I]beta-CIT SPECT study J. Neural Transm. 115 2008 721 729
5. P. Carmeliet Blood vessels and nerves: common signals, pathways and diseases Nat. Rev. Genet. 4 2003 710 720 (Pubitemid 37046138)
6. F. Ciccolini, T.J. Collins, J. Sudhoelter, P. Lipp, M.J. Berridge, and M.D. Bootman Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation J. Neurosci. 23 2003 103 111 (Pubitemid 36050409)
7. M.S. Davidoff, R. Middendorff, G. Enikolopov, D. Riethmacher, A.F. Holstein, and D. Müller Progenitor cells of the testosterone-producing Leydig cells revealed J. Cell Biol. 167 2004 935 944 (Pubitemid 39628115)
8. N. Emre, R. Coleman, and S. Ding A chemical approach to stem cell biology Curr. Opin. Chem. Biol. 11 2007 252 258 (Pubitemid 46963068)
9. A.J. Firestone, and J.K. Chen Controlling destiny through chemistry: small-molecule regulators of cell fate ACS Chem. Biol. 5 2010 15 34
10. G. Gloire, S. Legrand-Poels, and J. Piette NF-kappaB activation by reactive oxygen species: fifteen years later Biochem. Pharmacol. 72 2006 1493 1505 (Pubitemid 44666727)
11. J. González-Maeso, R.L. Ang, T. Yuen, P. Chan, N.V. Weisstaub, J.F. López-Giménez, M. Zhou, Y. Okawa, L.F. Callado, G. Milligan, J.A. Gingrich, M. Filizola, J.J. Meana, and S.C. Sealfon Identification of a serotonin/glutamate receptor complex implicated in psychosis Nature 452 2008 93 97 (Pubitemid 351355090)
12. M.S. Hayden, and S. Ghosh Signaling to NF-kappaB Genes Dev. 18 2004 2195 2224
13. E.J. Huang, and L.F. Reichardt Trk receptors: roles in neuronal signal transduction Annu. Rev. Biochem. 72 2003 609 642 (Pubitemid 36930455)
14. T. Hussain, S. Gupta, and H. Mukhtar Cyclooxygenase-2 and prostate carcinogenesis Cancer Lett. 191 2003 125 135 (Pubitemid 36255597)
15. E.A. Jaffe, R.L. Nachman, C.G. Becker, and R.C. Minick Culture of human endothelial cells derived from umbilical veins J. Clin. Invest. 52 1973 2745 2756
16. D. Jordan Vagal control of the heart: central serotonergic (5-HT) mechanisms Exp. Physiol. 90 2005 175 181 (Pubitemid 40364795)
17. G. Kaplanski, N. Teysseire, C. Farnarier, S. Kaplanski, J.C. Lissitzky, J.M. Durand, J. Soubeyrand, C.A. Dinarello, and P. Bongrand IL-6 and IL-8 production from cultured human endothelial cells stimulated by infection with Rickettsia conorii via a cell-associated IL-1 alpha-dependent pathway J. Clin. Invest. 96 1995 2839 3344
18. W. Li, and S. Ding Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming Trends Pharmacol. Sci. 31 2010 36 45
19. C.N. Lynch, Y.C. Wang, J.K. Lund, Y.W. Chen, J.A. Leal, and S.R. Wiley TWEAK induces angiogenesis and proliferation of endothelial cells J. Biol. Chem. 274 1999 8455 8459 (Pubitemid 29164634)
20. J.Y. Miao, B.X. Zhao, H.H. Li, S.L. Zhang, and C.Q. Du Effect of safrole oxide on vascular endothelial cell growth and apoptosis induced by deprivation of fibroblast growth factor Acta Pharmacol. Sin. 23 2002 323 326
21. D. Nikolic, and R.B. van Breemen DNA oxidation induced by cyclooxygenase-2 Chem. Res. Toxicol. 14 2001 351 354 (Pubitemid 32367467)
22. K. Ozawa, M. Seo, and T. Imamura A quantitative method for evaluation of FGF family and FGF receptor family gene expression by RT-PCR Brain Res. Brain Res. Protoc. 1 1997 211 216 (Pubitemid 28281314)
23. S. Papa, C. Bubici, F. Zazzeroni, C.G. Pham, C. Kuntzen, J.R. Knabb, K. Dean, and G. Franzoso The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease Cell Death Differ. 13 2006 712 729
24. S.K. Pathak, R.A. Sharma, W.P. Steward, J.K. Mellon, T.R. Griffiths, and A.J. Gescher Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: targets for chemopreventive strategies Eur. J. Cancer 41 2005 61 70 (Pubitemid 40029659)
25. T.A. Patterson, E.K. Lobenhofer, S.B. Fulmer-Smentek, P.J. Collins, T.M. Chu, W. Bao, H. Fang, E.S. Kawasaki, J. Hager, I.R. Tikhonova, S.J. Walker, L. Zhang, P. Hurban, F. de Longueville, J.C. Fuscoe, W. Tong, L. Shi, and R.D. Wolfinger Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project Nat. Biotechnol. 24 2006 1140 1150 (Pubitemid 44359726)
26. A.S. Rice, and R.G. Hill New treatments for neuropathic pain Annu. Rev. Med. 57 2006 535 551 (Pubitemid 43262006)
27. S. Sakao, L. Taraseviciene-Stewart, J.D. Lee, K. Wood, C.D. Cool, and N.F. Voelkel Vascular endothelial growth factor receptor blockade by SU5416 combined with pulsatile shear stress causes apoptosis and subsequent proliferation of apoptosis-resistant endothelial cells Chest 128 2005 610 611
28. + precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells FASEB J. 21 2007 3640 3652 (Pubitemid 350075152)
29. R.A. Segal Selectivity in neurotrophin signaling: theme and variations Annu. Rev. Neurosci. 26 2003 299 330 (Pubitemid 37064936)
30. Y. Shibata, R. Branicky, I.O. Landaverde, and S. Hekimi Redox regulation of germline and vulval development in Caenorhabditis elegans Science 302 2003 1779 1782 (Pubitemid 37505744)
31. L. Su, J. Zhao, B.X. Zhao, J.Y. Miao, D.L. Yin, and S.L. Zhang Safrole oxide induced human umbilical vein vascular endothelial cell differentiation into neuron-like cells by depressing the reactive oxygen species level at the low concentration Biochim. Biophys. Acta 1763 2006 247 253
32. N. Suematsu, H. Tsutsui, J. Wen, D. Kang, M. Ikeuchi, T. Ide, S. Hayashidani, T. Shiomi, T. Kubota, N. Hamasaki, and A. Takeshita Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes Circulation 107 2003 1418 1423 (Pubitemid 36350742)
33. E. Szabadi Drugs for sleep disorders: mechanisms and therapeutic prospects Br. J. Clin. Pharmacol. 61 2006 761 766 (Pubitemid 43794807)
34. D.J. Wadleigh, S.T. Reddy, E. Kopp, S. Ghosh, and H.R. Herschman Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages J. Biol. Chem. 275 2000 6259 6266 (Pubitemid 30129916)
35. W. Wang, X. Liu, J. Zhao, B. Zhao, S. Zhang, and J. Miao A novel butyrolactone derivative inhibited apoptosis and depressed integrin beta4 expression in vascular endothelial cells Bioorg. Med. Chem. Lett. 17 2007 482 485 (Pubitemid 46073740)
36. X. Wang, S.V. McLennan, T.J. Allen, and S.M. Twigg Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes J. Cell Commun. Signal 4 2010 15 23
37. Y.Y. Zhang, J.L. Walker, A. Huang, J.F. Keaney, C.B. Clish, C.N. Serhan, and J. Loscalzo Expression of 5-lipoxygenase in pulmonary artery endothelial cells Biochem. J. 361 2002 267 276 (Pubitemid 34174493)
38. B.X. Zhao, D.W. Wang, H. Zuo, G.T. Qian, and J.Y. Miao Synthesis and bioactivity of 1-alkoxy (phenoxy)-3-piperonyl-2-propanol Chin. J. Org. Chem. 23 2003 1026 1028
39. J. Zhao, J. Miao, B. Zhao, and S. Zhang Upregulating of Fas, integrin beta4 and P53 and depressing of PC-PLC activity and ROS level in VEC apoptosis by safrole oxide FEBS Lett. 579 2005 5809 5813 (Pubitemid 41455668)
40. J. Zhao, J. Miao, B. Zhao, S. Zhang, and D. Yin Suppressing Akt phosphorylation and activating Fas by safrole oxide inhibited angiogenesis and induced vascular endothelial cell apoptosis in the presence of fibroblast growth factor-2 and serum Int. J. Biochem. Cell Biol. 38 2006 1603 1613 (Pubitemid 43729307)