The rapidly expanding CREC protein family: Members, localization, function, and role in disease

BioEssays

Volumn 31, Issue 3, 2009, Pages 262-277

  Honoré, Bent ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Cab45; Calumenin; ERC 55; Reticulocalbin; Reticulocalbin 3

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BIOLOGICAL MARKER; CALCIUM BINDING PROTEIN; CALUMENIN; CELL PROTEIN; PROTEIN CREC; PROTEIN ERC 55; PROTEIN SDF4; RETICULOCALBIN 1; RETICULOCALBIN 2; RETICULOCALBIN 3; RYANODINE RECEPTOR 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; CALCIUM TRANSPORT; CARBOXYLATION; CELL SURFACE; CYTOSOL; ENDOPLASMIC RETICULUM; EXTRACELLULAR SPACE; HEART CONTRACTION; HUMAN; NEOPLASM; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; CALCIUM-BINDING PROTEINS; DISEASE; HUMANS; PROTEIN TRANSPORT; TRANSCRIPTION, GENETIC;

EID: 65249104606     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.200800186     Document Type: Review

References (102)

1. 2+-binding proteins localised to the secretory pathway of mammalian cells. FEBS Lett 2000. 466: 11-18.
2. 2+-binding protein with multiple EF-hand motifs and a carboxyl-terminalHDEL sequence. J Biol Chem 1993. 268: 699-705.
3. Cooper, C. R., Graves, B., Pruitt, F., Chaib, H., Lynch, J. E., et al. Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha. J Cell Biochem 2008. 104: 2298-2309.
4. Kent, J., Lee, M., Schedl, A., Boyle, S., Fantes, J., et al. The reticulocalbin gene maps to the WAGR region in human and to the Small eye Harwell deletion in mouse. Genomics 1997. 42: 260-267.
5. Tyedmers, J., Lerner, M., Nastainczyk, W. and Zimmermann, R., Calumenin and reticulocalbin are associated with the protein translocase of the mammalian endoplasmic reticulum. J Biol Sci 2005. 5: 70-75.
6. Weis, K., Griffiths, G. and Lamond, A. I., The endoplasmic reticulum calcium-binding protein of 55 kDa is a novel EF-hand protein retained in the endoplasmic reticulum by a carboxyl-terminal His-Asp-Glu-Leu motif. J Biol Chem 1994. 269: 19142-19150.
7. Dodds, D., Schlimgen, A. K., Lu, S. Y. and Perin, M. S., Novel reticular calcium binding protein is purified on taipoxin columns. J Neurochem 1995. 64: 2339-2344.
8. Chen, J. J., Reid, C. E., Band, V. and Androphy, E. J., Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein. Science 1995. 269: 529-531.
9. Imai, T., Matsuda, K., Shimojima, T., Hashimoto, T., Masuhiro, Y., et al. ERC-55, a binding protein for the papilloma virus E6 oncoprotein, specifically interacts with vitamin D receptor among nuclear receptors. Biochem Biophys Res Commun 1997. 233: 765-769.
10. Alexander, J. S., Minagar, A., Harper, M., Robinson-Jackson, S., Jennings, M., et al. Proteomic analysis of human cerebral endothelial cells activated by multiple sclerosis serum and IFNbeta-1b. J Mol Neurosci 2007. 32: 169-178.
11. Tsuji, A., Kikuchi, Y., Sato, Y., Koide, S., Yuasa, K., et al. A proteomic approach reveals transient association of reticulocalbin-3, a novel member of the CREC family, with the precursor of subtilisin-like proprotein convertase, PACE4. Biochem J 2006. 396: 51-59.
12. 2+-binding protein localized to the Golgi lumen. J Cell Biol 1996. 133: 257-268.
13. Lam, P. P., Hyvarinen, K., Kauppi, M., Cosen-Binker, L., Laitinen, S., et al. A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. Mol Biol Cell 2007. 18: 2473-2480.
14. Grønborg, M., Kristiansen, T. Z., Iwahori, A., Chang, R., Reddy, R., et al. Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol Cell Proteomics 2006. 5: 157-171.
15. Lara-Lemus, R., Liu, M., Turner, M. D., Scherer, P., Stenbeck, G., et al. Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell. J Cell Sci 2006. 119: 1833-1842.
16. 2+-binding protein retained in the endoplasmic reticulum with a novel carboxyl-terminal sequence, HDEF. J Biol Chem 1997. 272: 18232-18239.
17. 2+-binding activity. Biochim Biophys Acta 1998. 1386: 121-131.
18. Vorum, H., Hager, H., Christensen, B. M., Nielsen, S. and Honoré, B., Human calumenin localizes to the secretory pathway and is secreted to the medium. Exp Cell Res 1999. 248: 473-481.
19. Coppinger, J. A., Cagney, G., Toomey, S., Kislinger, T., Belton, O., et al. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 2004. 103: 2096-2104.
20. Jung, D. H. and Kim, D. H., Characterization of isoforms and genomic organization of mouse calumenin. Gene 2004. 327: 185-194.
21. Hseu, M. J., Yen, C. Y., Tseng, C. C. and Tzeng, M. C., Purification and partial amino acid sequence of a novel protein of the reticulocalbin family. Biochem Biophys Res Commun 1997. 239: 18-22.
22. Hseu, M. J., Yen, C. H. and Tzeng, M. C., Crocalbin: a new calcium-binding protein that is also a binding protein for crotoxin, a neurotoxic phospholipase A2. FEBS Lett 1999. 445: 440-444.
23. Olsen, J. V., Blagoev, B., Gnad, F., Macek, B., Kumar, C., et al. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 2006. 127: 635-648.
24. Beausoleil, S. A., Villen, J., Gerber, S. A., Rush, J. and Gygi, S. P., A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat Biotechnol 2006. 24: 1285-1292.
25. Shah, K. and Shokat, K. M., A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway. Chem Biol 2002. 9: 35-47.
26. 2+-binding protein with multiple EF-hand motifs. J Biochem 1995. 117: 1113-1119.
27. Yabe, D., Taniwaki, M., Nakamura, T., Kanazawa, N., Tashiro, K., et al. Human calumenin gene (CALU): cDNA isolation and chromosomal mapping to 7q32. Genomics 1998. 49: 331-333.
28. Fukuda, T., Oyamada, H., Isshiki, T., Maeda, M., Kusakabe, T., et al. Distribution and variable expression of secretory pathway protein reticulocalbin in normal human organs and non-neoplastic pathological conditions. J Histochem Cytochem 2007. 55: 335-345.
29. Honoré, B. and Østergaard, M., Transcriptomics and proteomics: integration? In: Cooper, D. N. editor. Nature Encyclopedia of the Human Genome, Vol. 5. London, Nature Publishing Group, 2003. pp 579-584.
30. Zhang, Y., Ye, J., Chen, D., Zhao, X., Xiao, X., et al. Differential expression profiling between the relative normal and dystrophic muscle tissues from the same LGMD patient. J Transl Med 2006. 4: 53.
31. Liu, Z., Brattain, M. G. and Appert, H., Differential display of reticulocalbin in the highly invasive cell line, MDA-MB-435, versus the poorly invasive cell line, MCF-7. Biochem Biophys Res Commun 1997. 231: 283-289.
32. Nimmrich, I., Erdmann, S., Melchers, U., Finke, U., Hentsch, S., et al. Seven genes that are differentially transcribed in colorectal tumor cell lines. Cancer Lett 2000. 160: 37-43.
33. Yu, L. R., Zeng, R., Shao, X. X., Wang, N., Xu, Y. H., et al. Identification of differentially expressed proteins between human hepatoma and normal liver cell lines by two-dimensional electrophoresis and liquid chromatography-ion trap mass spectrometry. Electrophoresis 2000. 21: 3058-3068.
34. Hirano, T., Kato, H., Maeda, M., Gong, Y., Shou, Y., et al. Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker. Int J Cancer 2005. 117: 460-468.
35. 2-resistant lens epithelial cell line. Free Radic Biol Med 2001. 31: 90-97.
36. Mazzucchelli, G. D., Gabelica, V., Smargiasso, N., Fleron, M., Ashimwe, W., et al. Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Sci 2008. 6: 12.
37. Jiménez, C. R., Stam, F. J., Wan Li, K., Gouwenberg, Y., Hornshaw, M. P., et al. Proteomics of the injured rat sciatic nerve reveals protein expression dynamics during regeneration. Mol Cell Proteomics 2005. 4: 120-132.
38. Reynolds, J. L., Mahajan, S. D., Sykes, D. and Nair, M. P., Heroin-induces differential protein expression by normal human astrocytes (NHA). Am J Infect Dis 2006. 2: 49-57.
39. Gardini, G., Del Boccio, P., Colombatto, S., Testore, G., Corpillo, D., et al. Proteomic investigation in the detection of the illicit treatment of calves with growth-promoting agents. Proteomics 2006. 6: 2813-2822.
40. Hengstschlager, M., Rosner, M., Fountoulakis, M. and Lubec, G., The cellular response to ectopic overexpression of the tuberous sclerosis genes, TSC1 and TS C2: a proteomic approach. Int J Oncol 2005. 27: 831-838.
41. Wang, Q., Zhu, X., Xu, Q., Ding, X., Chen, Y. E., et al. Effect of C-reactive protein on gene expression in vascular endothelial cells. Am J Physiol Heart Circ Physiol 2005. 288: H1539-H1545.
42. Jiang, P. Z., Gan, M., Huang, H., Shen, X. M., Wang, S., et al. Proteomics-based identification of proteins with altered expression induced by 12-O-tetradecanoylphorbol 13-acetate in nasopharyngeal carcinoma CNE2 cells. Acta Biochim Biophys Sin (Shanghai) 2005. 37: 97-106.
43. Tong, A., Zhang, H., Li, Z., Gou, L., Wang, Z., et al. Proteomic analysis of liver cancer cells treated with suberonylanilide hydroxamic acid. Cancer Chemother Pharmacol 2008. 61: 791-802.
44. Sinha, P., Poland, J., Schnolzer, M., Celis, J. E. and Lage, H., Characterization of the differential protein expression associated with thermoresistance in human gastric carcinoma cell lines. Electrophoresis 2001. 22: 2990-3000.
45. Poland, J., Schadendorf, D., Lage, H., Schnolzer, M., Celis, J. E., et al. Study of therapy resistance in cancer cells with functional proteome analysis. Clin Chem Lab Med 2002. 40: 221-234.
46. Helbig, I., Matigian, N. A., Vadlamudi, L., Lawrence, K. M., Bayly, M. A., et al. Gene expression analysis in absence epilepsy using a monozygotic twin design. Epilepsia 2008. 49: 1546-1554.
47. Cavallo, F., Astolfi, A., Iezzi, M., Cordero, F., Lollini, P. L., et al. An integrated approach of immunogenomics and bioinformatics to identify new tumor associated antigens (TAA) for mammary cancer immunological prevention. BMC Bioinformatics 2005. 6: S7.
48. Vazquez-Ortiz, G., Garcia, J. A., Ciudad, C. J., Noe, V., Penuelas, S., et al. Differentially expressed genes between high-risk human papillomavirus types in human cervical cancer cells. Int J Gynecol Cancer 2007. 17: 484-491.
49. Park, W. Y., Hwang, C. I., Kang, M. J., Seo, J. Y., Chung, J. H., et al. Gene profile of replicative senescence is different from progeria or elderly donor. Biochem Biophys Res Commun 2001. 282: 934-939.
50. Strefford, J. C., Lane, T. M., Hill, A., LeRoux, L., Foot, N. J., et al. Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP. Cytogenet Genome Res 2006. 112: 45-52.
51. Zhu, Y., Wang, Q., Xu, W. and Li, S., The ethanol response gene Cab45 can modulate the impairment elicited by ethanol and ultraviolet in PC12 cells. J Genet Genomics 2008. 35: 153-161.
52. Pass, H. I., Liu, Z.,Wall, A., Bueno, R., Land, S., et al. Gene expression profiles predict survival and progression of pleural mesothelioma. Clin Cancer Res 2004. 10: 849-859.
53. Shen, C., Hui-Zhao, Wang, D., Jiang, G., Wang, J., et al. Molecular cloning, identification and analysis of lung squamous cell carcinoma-related genes. Lung Cancer 2002. 38: 235-241.
54. Wu, W., Tang, X., Hu, W., Lotan, R., Hong, W. K., et al. Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry. Clin Exp Metastasis 2002. 19: 319-326.
55. Ding, S. J., Li, Y., Shao, X. X., Zhou, H., Zeng, R., et al. Proteome analysis of hepatocellular carcinoma cell strains, MHCC97-H and MHCC97-L, with different metastasis potentials. Proteomics 2004. 4: 982-994.
56. Pocernich, C. B., Boyd-Kimball, D., Poon, H. F., Thongboonkerd, V., Lynn, B. C., et al. Proteomics analysis of human astrocytes expressing the HIV protein Tat. Brain Res Mol Brain Res 2005. 133: 307-316.
57. Nakazawa, T., Nakajima, A., Seki, N., Okawa, A., Kato, M., et al. Gene expression of periostin in the early stage of fracture healing detected by cDNA microarray analysis. J Orthop Res 2004. 22: 520-525.
58. Grzeskowiak, R., Witt, H., Drungowski, M., Thermann, R., Hennig, S., et al. Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovasc Res 2003. 59: 400-411.
59. Takahashi, J., Susa, T., Sato, T., Asano, H., Kato, T., et al. Analysis of genes expressed during porcine fetal pituitary development by suppressive subtraction hybridization. J Reprod Dev 2007. 53: 1087-1091.
60. Huang, Y. H., Chang, A. Y., Huang, C. M., Huang, S. W. and Chan, S. H., Proteomic analysis of lipopolysaccharide-induced apoptosis in PC12 cells. Proteomics 2002. 2: 1220-1228.
61. Castagna, A., Antonioli, P., Astner, H., Hamdan, M., Righetti, S. C., et al. A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431. Proteomics 2004. 4: 3246-3267.
62. Fietta, A., Bardoni, A., Salvini, R., Passadore, I., Morosini, M., et al. Analysis of bronchoalveolar lavage fluid proteome from systemic sclerosis patients with or without functional, clinical and radiological signs of lung fibrosis. Arthritis Res Ther 2006. 8: R160.
63. Terrier, B., Tamby, M. C., Camoin, L., Guilpain, P., Broussard, C., et al. Identification of target antigens of anti-fibroblast antibodies in pulmonary arterial hypertension. Am J Respir Crit Care Med 2008. 177: 1128-1134.
64. Liu, Y., Chen, J. J., Gao, Q., Dalal, S., Hong, Y., et al. Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells. J Virol 1999. 73: 7297-7307.
65. Sherman, L., Itzhaki, H., Jackman, A., Chen, J. J., Koval, D., et al. Inhibition of serum- and calcium-induced terminal differentiation of human keratinocytes by HPV 16 E6: study of the association with p53 degradation, inhibition of p53 transactivation, and binding to E6BP. Virology 2002. 292: 309-320.
66. Lichtig, H., Algrisi, M., Botzer, L. E., Abadi, T., Verbitzky, Y., et al. HPV16 E6 natural variants exhibit different activities in functional assays relevant to the carcinogenic potential of E6. Virology 2006. 350: 216-227.
67. Rothman, J. E., Lasker Basic Medical Research Award. The machinery and principles of vesicle transport in the cell. Nat Med 2002. 8: 1059-1062.
68. Furie, B. and Furie, B. C., The molecular basis of blood coagulation. Cell 1988. 53: 505-518.
69. Furie, B. and Furie, B. C., Molecular basis of vitamin K-dependent γ-carboxylation. Blood 1990. 75: 1753-1762.
70. Suttie, J. W., Vitamin K-dependent carboxylase. Annu Rev Biochem 1985. 54: 459-477.
71. Cranenburg, E. C., Schurgers, L. J. and Vermeer, C., Vitamin K: the coagulation vitamin that became omnipotent. Thromb Haemost 2007. 98: 120-125.
72. Sadler, J. E., Medicine: K is for koagulation. Nature 2004. 427: 493-494.
73. Rost, S., Fregin, A., Ivaskevicius, V., Conzelmann, E., Hortnagel, K., et al. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 2004. 427: 537-541.
74. Li, T., Chang, C. Y., Jin, D. Y., Lin, P. J., Khvorova, A., et al. Identification of the gene for vitamin K epoxide reductase. Nature 2004. 427: 541-544.
75. Oldenburg, J., Watzka, M., Rost, S. and Muller, C. R., VKOR C1: molecular target of coumarins. J Thromb Haemost 2007. 5: 1-6.
76. Wallin, R., Hutson, S. M., Cain, D., Sweatt, A. and Sane, D. C., A molecular mechanism for genetic warfarin resistance in the rat. FASEB J 2001. 15: 2542-2544.
77. Wajih, N., Sane, D. C., Hutson, S. M. and Wallin, R., The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system: characterization of the system in normal and warfarin-resistant rats. J Biol Chem 2004. 279: 25276-25283.
78. Wallin, R. and Hutson, S. M., Warfarin and the vitamin K-dependent gamma-carboxylation system. Trends Mol Med 2004. 10: 299-302.
79. Wajih, N., Hutson, S. M. and Wallin, R., siRNA silencing of calumenin enhances functional factor IX production. Blood 2006. 108: 3757-3760.
80. Wajih, N., Owen, J. and Wallin, R., Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection. Thromb Res 2008. 122: 405-410.
81. Kimura, R., Kokubo, Y., Miyashita, K., Otsubo, R., Nagatsuka, K., et al. Polymorphisms in vitamin K-dependent gamma-carboxylation-related genes influence interindividual variability in plasma protein C and protein S activities in the general population. Int J Hematol 2006. 84: 387-397.
82. Gonzalez-Conejero, R., Corral, J., Roldan, V., Ferrer, F., Sanchez-Serrano, I., et al. The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol. J Thromb Haemost 2007. 5: 1701-1706.
83. Vecsler, M., Loebstein, R., Almog, S., Kurnik, D., Goldman, B., et al. Combined genetic profiles of components and regulators of the vitamin K-dependent gamma-carboxylation system affect individual sensitivity to warfarin. Thromb Haemost 2006. 95: 205-211.
84. Wadelius, M., Chen, L. Y., Eriksson, N., Bumpstead, S., Ghori, J., et al. Association of warfarin dose with genes involved in its action and metabolism. Hum Genet 2007. 121: 23-34.
85. 2+. A. potential role in haemostasis and thrombosis. Mol Cell Biochem 2009. 320: 25-33.
86. Bornstein, P., Thrombospondins as matricellular modulators of cell function. J Clin Invest 2001. 107: 929-934.
87. Østergaard, M., Hansen, G. A. W., Vorum, H. and Honoré, B., Proteomic profiling of fibroblasts reveals a modulating effect of extracellular calumenin on the organization of the actin cytoskeleton. Proteomics 2006. 6: 3509-3519.
88. 2+-binding protein, interacts with ryanodine receptor-1 in rabbit skeletal sarcoplasmic reticulum. Biochem Biophys Res Commun 2006. 343: 34-42.
89. Sahoo, S. and Kim, D. H., Calumenin Interacts with SERCA2 in rat cardiac sarcoplasmic reticulum. Mol Cells 2008. 26: 265-269.
90. Most, P., Remppis, A., Pleger, S. T., Katus, H. A. and Koch, W. J., S100 A1: a novel inotropic regulator of cardiac performance. Transition from molecular physiology to pathophysiological relevance. Am J Physiol Regul Integr Comp Physiol 2007. 293: R568-R577.
91. Kettlewell, S., Most, P., Currie, S., Koch, W. J. and Smith, G. L., S100A1 increases the gain of excitation-contraction coupling in isolated rabbit ventricular cardiomyocytes. J Mol Cell Cardiol 2005. 39: 900-910.
92. 2+-ATPase2a and phospholamban in the human heart. Biochem Biophys Res Commun 2003. 306: 550-557.
93. Yamasaki, R., Berri, M., Wu, Y., Trombitas, K., McNabb, M., et al. Titin-actin interaction in mouse myocardium: passive tension modulation and its regulation by calcium/S100A1. Biophys J 2001. 81: 2297-2313.
94. 1-ATPase leads to an increased ATP content in cardiomyocytes. Mol Cell Biol 2007. 27: 4365-4373.
95. 2+-binding protein S100A1 in human cardiomyopathy. Biochim Biophys Acta 1996. 1313: 253-257.
96. Fohlman, J., Eaker, D., Karlsoon, E. and Thesleff, S., Taipoxin, an extremely potent presynaptic neurotoxin from the venom of the australian snake taipan (Oxyuranus s. scutellatus). Isolation, characterization, quaternary structure and pharmacological properties. Eur J Biochem 1976. 68: 457-469.
97. Dodds, D. C., Omeis, I. A., Cushman, S. J., Helms, J. A. and Perin, M. S., Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin-associated calcium-binding protein 49. J Biol Chem 1997. 272: 21488-21494.
98. Kirkpatrick, L. L., Matzuk, M. M., Dodds, D. C. and Perin, M. S., Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2. J Biol Chem 2000. 275: 17786-17792.
99. Bonanomi, D., Pennuto, M., Rigoni, M., Rossetto, O., Montecucco, C., et al. Taipoxin induces synaptic vesicle exocytosis and disrupts the interaction of synaptophysin I with VAMP2. Mol Pharmacol 2005. 67: 1901-1908.
100. Gorlich, D. and Rapoport, T. A., Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane. Cell 1993. 75: 615-630.
101. Meyer, H. A., Grau, H., Kraft, R., Kostka, S., Prehn, S., et al. Mammalian Sec61 is associated with Sec62 and Sec63. J Biol Chem 2000. 275: 14550-14557.
102. Vorum, H., Jacobsen, C. and Honoré, B., Calumenin interacts with serum amyloid P component. FEBS Lett 2000. 465: 129-134.