-
2
-
-
67650217963
-
The presence and severity of chronic kidney disease predicts all-cause mortality in type 1 diabetes
-
Groop PH, Thomas MC, Moran JL, et al. The presence and severity of chronic kidney disease predicts all-cause mortality in type 1 diabetes. Diabetes 2009; 58(7): 1651-1658.
-
(2009)
Diabetes
, vol.58
, Issue.7
, pp. 1651-1658
-
-
Groop, P.H.1
Thomas, M.C.2
Moran, J.L.3
-
3
-
-
79960789572
-
Inflammation and diabetic retinal microvascular complications
-
Zhang W, Liu H, Al-Shabrawey M, Caldwell RW, Caldwell RB. Inflammation and diabetic retinal microvascular complications. J Cardiovasc Dis Res 2011; 2(2): 96-103.
-
(2011)
J Cardiovasc Dis Res
, vol.2
, Issue.2
, pp. 96-103
-
-
Zhang, W.1
Liu, H.2
Al-Shabrawey, M.3
Caldwell, R.W.4
Caldwell, R.B.5
-
4
-
-
78349297565
-
Oxidative stress and diabetic complications
-
Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010; 107(9): 1058-1070.
-
(2010)
Circ Res
, vol.107
, Issue.9
, pp. 1058-1070
-
-
Giacco, F.1
Brownlee, M.2
-
5
-
-
0035180299
-
Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
-
Du XL, Edelstein D, Dimmeler S, Ju Q, Sui C, Brownlee M. Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 2001; 108(9): 1341-1348.
-
(2001)
J Clin Invest
, vol.108
, Issue.9
, pp. 1341-1348
-
-
Du, X.L.1
Edelstein, D.2
Dimmeler, S.3
Ju, Q.4
Sui, C.5
Brownlee, M.6
-
6
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
Fulton D, Gratton JP, McCabe TJ, et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 1999; 399(6736): 597-601.
-
(1999)
Nature
, vol.399
, Issue.6736
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
-
7
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999; 399(6736): 601-605.
-
(1999)
Nature
, vol.399
, Issue.6736
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
8
-
-
0029159779
-
Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
-
De Caterina R, Libby P, Peng HB, et al. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 1995; 96(1): 60-68.
-
(1995)
J Clin Invest
, vol.96
, Issue.1
, pp. 60-68
-
-
De Caterina, R.1
Libby, P.2
Peng, H.B.3
-
9
-
-
0023756850
-
The discovery of nitric oxide as the endogenous nitrovasodilator
-
Moncada S, Palmer RM, Higgs EA. The discovery of nitric oxide as the endogenous nitrovasodilator. Hypertension 1988; 12(4): 365-372.
-
(1988)
Hypertension
, vol.12
, Issue.4
, pp. 365-372
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
10
-
-
20444503774
-
Pathogenesis of diabetic microvascular complications
-
(3rd edn), eds. John Wiley & Sons Ltd: London
-
He Z, Rask-Madsen C, King GL. Pathogenesis of diabetic microvascular complications. In International textbook of diabetes mellitus (3rd edn) DeFronzo RA, Ferrannini E, Keen H, Zimmet P, eds. John Wiley & Sons Ltd: London, 2004; 1135-1159.
-
(2004)
International textbook of diabetes mellitus
, pp. 1135-1159
-
-
He, Z.1
Rask-Madsen, C.2
King, G.L.3
DeFronzo, R.A.4
Ferrannini, E.5
Keen, H.6
Zimmet, P.7
-
11
-
-
77949777124
-
Diabetes is a proinflammatory state: a translational perspective
-
Devaraj S, Dasu MR, Jialal I. Diabetes is a proinflammatory state: a translational perspective. Expert Rev Endocrinol Metab 2010; 5(1): 19-28.
-
(2010)
Expert Rev Endocrinol Metab
, vol.5
, Issue.1
, pp. 19-28
-
-
Devaraj, S.1
Dasu, M.R.2
Jialal, I.3
-
12
-
-
17444405235
-
Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes - the EURODIAB Prospective Complications Study
-
Schram MT, Chaturvedi N, Schalkwijk CG, Fuller JH, Stehouwer CD. Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes - the EURODIAB Prospective Complications Study. Diabetologia 2005; 48(2): 370-378.
-
(2005)
Diabetologia
, vol.48
, Issue.2
, pp. 370-378
-
-
Schram, M.T.1
Chaturvedi, N.2
Schalkwijk, C.G.3
Fuller, J.H.4
Stehouwer, C.D.5
-
13
-
-
33646032701
-
Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in type 1 diabetic patients
-
Soedamah-Muthu SS, Chaturvedi N, Schalkwijk CG, Stehouwer CD, Ebeling P, Fuller JH. Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in type 1 diabetic patients. J Diabetes Complications 2006; 20(3): 188-195.
-
(2006)
J Diabetes Complications
, vol.20
, Issue.3
, pp. 188-195
-
-
Soedamah-Muthu, S.S.1
Chaturvedi, N.2
Schalkwijk, C.G.3
Stehouwer, C.D.4
Ebeling, P.5
Fuller, J.H.6
-
14
-
-
0036436681
-
Macrophages from high-risk HLA-DQB1*0201/*0302 type 1 diabetes mellitus patients are hypersensitive to lipopolysaccharide stimulation
-
Plesner A, Greenbaum CJ, Gaur LK, Ernst RK, Lernmark A. Macrophages from high-risk HLA-DQB1*0201/*0302 type 1 diabetes mellitus patients are hypersensitive to lipopolysaccharide stimulation. Scand J Immunol 2002; 56(5): 522-529.
-
(2002)
Scand J Immunol
, vol.56
, Issue.5
, pp. 522-529
-
-
Plesner, A.1
Greenbaum, C.J.2
Gaur, L.K.3
Ernst, R.K.4
Lernmark, A.5
-
15
-
-
0035138314
-
Oxidative stress in families of type 1 diabetic patients: further evidence
-
Matteucci E, Giampietro O. Oxidative stress in families of type 1 diabetic patients: further evidence. Diabetes Care 2001; 24(1): 167-168.
-
(2001)
Diabetes Care
, vol.24
, Issue.1
, pp. 167-168
-
-
Matteucci, E.1
Giampietro, O.2
-
16
-
-
34548854245
-
Increased expression of monocyte CD11b (Mac-1) in overweight recent-onset type 1 diabetic children
-
Cifarelli V, Libman IM, Deluca A, Becker D, Trucco M, Luppi P. Increased expression of monocyte CD11b (Mac-1) in overweight recent-onset type 1 diabetic children. Rev Diabet Stud 2007; 4(2): 112-117.
-
(2007)
Rev Diabet Stud
, vol.4
, Issue.2
, pp. 112-117
-
-
Cifarelli, V.1
Libman, I.M.2
Deluca, A.3
Becker, D.4
Trucco, M.5
Luppi, P.6
-
17
-
-
38049154864
-
Sustained IL-1alpha, IL-4, and IL-6 elevations following correction of hyperglycemia in children with type 1 diabetes mellitus
-
Rosa JS, Flores RL, Oliver SR, Pontello AM, Zaldivar FP, Galassetti PR. Sustained IL-1alpha, IL-4, and IL-6 elevations following correction of hyperglycemia in children with type 1 diabetes mellitus. Pediatr Diabetes 2008; 9(1): 9-16.
-
(2008)
Pediatr Diabetes
, vol.9
, Issue.1
, pp. 9-16
-
-
Rosa, J.S.1
Flores, R.L.2
Oliver, S.R.3
Pontello, A.M.4
Zaldivar, F.P.5
Galassetti, P.R.6
-
18
-
-
77954257829
-
Monocyte gene-expression profiles associated with childhood-onset type 1 diabetes and disease risk: a study of identical twins
-
Beyan H, Drexhage RC, van der Heul NL, et al. Monocyte gene-expression profiles associated with childhood-onset type 1 diabetes and disease risk: a study of identical twins. Diabetes 2010; 59(7): 1751-1755.
-
(2010)
Diabetes
, vol.59
, Issue.7
, pp. 1751-1755
-
-
Beyan, H.1
Drexhage, R.C.2
van der Heul, N.L.3
-
19
-
-
79959200769
-
Oxidative stress and redox modulation potential in type 1 diabetes
-
Delmastro MM, Piganelli JD. Oxidative stress and redox modulation potential in type 1 diabetes. Clin Dev Immunol 2011; 2011: 593863.
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 593863
-
-
Delmastro, M.M.1
Piganelli, J.D.2
-
20
-
-
0033030238
-
Plasma concentration of C-reactive protein is increased in type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation
-
Schalkwijk CG, Poland DC, van Dijk W, et al. Plasma concentration of C-reactive protein is increased in type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation. Diabetologia 1999; 42(3): 351-357.
-
(1999)
Diabetologia
, vol.42
, Issue.3
, pp. 351-357
-
-
Schalkwijk, C.G.1
Poland, D.C.2
van Dijk, W.3
-
21
-
-
0026498992
-
Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM
-
Lampeter ER, Kishimoto TK, Rothlein R, et al. Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM. Diabetes 1992; 41(12): 1668-1671.
-
(1992)
Diabetes
, vol.41
, Issue.12
, pp. 1668-1671
-
-
Lampeter, E.R.1
Kishimoto, T.K.2
Rothlein, R.3
-
22
-
-
0033371178
-
Abnormal markers of endothelial cell activation and oxidative stress in children, adolescents and young adults with type 1 diabetes with no clinical vascular disease
-
Elhadd TA, Kennedy G, Hill A, et al. Abnormal markers of endothelial cell activation and oxidative stress in children, adolescents and young adults with type 1 diabetes with no clinical vascular disease. Diabetes Metab Res Rev 1999; 15(6): 405-411.
-
(1999)
Diabetes Metab Res Rev
, vol.15
, Issue.6
, pp. 405-411
-
-
Elhadd, T.A.1
Kennedy, G.2
Hill, A.3
-
23
-
-
8144230928
-
Endothelial dysfunction and increased arterial intima-media thickness in children with type 1 diabetes
-
Järvisalo MJ, Raitakari M, Toikka JO, et al. Endothelial dysfunction and increased arterial intima-media thickness in children with type 1 diabetes. Circulation 2004; 109(14): 1750-1755.
-
(2004)
Circulation
, vol.109
, Issue.14
, pp. 1750-1755
-
-
Järvisalo, M.J.1
Raitakari, M.2
Toikka, J.O.3
-
24
-
-
48649105081
-
Markers of endothelial dysfunction and inflammation in type 1 diabetic patients with or without diabetic nephropathy followed for 10years: association with mortality and decline of glomerular filtration rate
-
Astrup AS, Tarnow L, Pietraszek L, et al. Markers of endothelial dysfunction and inflammation in type 1 diabetic patients with or without diabetic nephropathy followed for 10years: association with mortality and decline of glomerular filtration rate. Diabetes Care 2008; 31(6): 1170-1176.
-
(2008)
Diabetes Care
, vol.31
, Issue.6
, pp. 1170-1176
-
-
Astrup, A.S.1
Tarnow, L.2
Pietraszek, L.3
-
25
-
-
40449113524
-
The role of inflammatory cytokines in diabetic nephropathy
-
Navarro-Gonzalez JF, Mora-Fernandez C. The role of inflammatory cytokines in diabetic nephropathy. J Am Soc Nephrol 2008; 19(3): 433-442.
-
(2008)
J Am Soc Nephrol
, vol.19
, Issue.3
, pp. 433-442
-
-
Navarro-Gonzalez, J.F.1
Mora-Fernandez, C.2
-
26
-
-
0014200189
-
Insulin biosynthesis: evidence for a precursor
-
Steiner DF, Cunningham D, Spigelman L, Aten B. Insulin biosynthesis: evidence for a precursor. Science 1967; 157(789): 697-700.
-
(1967)
Science
, vol.157
, Issue.789
, pp. 697-700
-
-
Steiner, D.F.1
Cunningham, D.2
Spigelman, L.3
Aten, B.4
-
27
-
-
84859520694
-
The clinical potential of C-peptide replacement in type 1 diabetes
-
Wahren J, Kallas A, Sima AA. The clinical potential of C-peptide replacement in type 1 diabetes. Diabetes 2012; 61(4): 761-772.
-
(2012)
Diabetes
, vol.61
, Issue.4
, pp. 761-772
-
-
Wahren, J.1
Kallas, A.2
Sima, A.A.3
-
28
-
-
80054110857
-
C-peptide reduces high glucose-induced apoptosis of endothelial cells and decreases NAD(P)H-oxidase reactive oxygen species generation
-
Cifarelli V, Geng X, Styche A, Lakomy M, Trucco M, Luppi P. C-peptide reduces high glucose-induced apoptosis of endothelial cells and decreases NAD(P)H-oxidase reactive oxygen species generation. Diabetologia 2011; 54: 2702-2712.
-
(2011)
Diabetologia
, vol.54
, pp. 2702-2712
-
-
Cifarelli, V.1
Geng, X.2
Styche, A.3
Lakomy, M.4
Trucco, M.5
Luppi, P.6
-
29
-
-
79955529615
-
C-peptide ameliorates kidney injury following hemorrhagic shock
-
Chima RS, Maltese G, Lamontagne T, et al. C-peptide ameliorates kidney injury following hemorrhagic shock. Shock 2011; 35(5): 524-529.
-
(2011)
Shock
, vol.35
, Issue.5
, pp. 524-529
-
-
Chima, R.S.1
Maltese, G.2
Lamontagne, T.3
-
30
-
-
79955376981
-
C-peptide and long-term complications of diabetes
-
Luppi P, Cifarelli V, Wahren J. C-peptide and long-term complications of diabetes. Pediatr Diabetes 2011; 12(3): 276-292.
-
(2011)
Pediatr Diabetes
, vol.12
, Issue.3
, pp. 276-292
-
-
Luppi, P.1
Cifarelli, V.2
Wahren, J.3
-
31
-
-
84872019417
-
C-Peptide prevents hyperglycemia-induced endothelial apoptosis through inhibition of reactive oxygen species-mediated transglutaminase 2 activation
-
Bhatt MP, Lim YC, Hwang J, Na S, Kim YM, Ha KS. C-Peptide prevents hyperglycemia-induced endothelial apoptosis through inhibition of reactive oxygen species-mediated transglutaminase 2 activation. Diabetes 2013; 62(1): 243-253.
-
(2013)
Diabetes
, vol.62
, Issue.1
, pp. 243-253
-
-
Bhatt, M.P.1
Lim, Y.C.2
Hwang, J.3
Na, S.4
Kim, Y.M.5
Ha, K.S.6
-
32
-
-
84887607405
-
C-Peptide reduces mitochondrial superoxide generation by restoring complex I activity in high glucose-exposed renal microvascular endothelial cells
-
Vejandla H, Hollander JM, Kothur A, Brock RW. C-Peptide reduces mitochondrial superoxide generation by restoring complex I activity in high glucose-exposed renal microvascular endothelial cells. ISRN Endocrinol 2012; 2012: 162802.
-
(2012)
ISRN Endocrinol
, vol.2012
, pp. 162802
-
-
Vejandla, H.1
Hollander, J.M.2
Kothur, A.3
Brock, R.W.4
-
33
-
-
0141704071
-
C-peptide enhances insulin-mediated cell growth and protection against high glucose-induced apoptosis in SH-SY5Y cells
-
Li ZG, Zhang W, Sima AA. C-peptide enhances insulin-mediated cell growth and protection against high glucose-induced apoptosis in SH-SY5Y cells. Diabetes Metab Res Rev 2003; 19(5): 375-385.
-
(2003)
Diabetes Metab Res Rev
, vol.19
, Issue.5
, pp. 375-385
-
-
Li, Z.G.1
Zhang, W.2
Sima, A.A.3
-
34
-
-
17844388643
-
The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats
-
Sima AA, Li ZG. The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats. Diabetes 2005; 54(5): 1497-1505.
-
(2005)
Diabetes
, vol.54
, Issue.5
, pp. 1497-1505
-
-
Sima, A.A.1
Li, Z.G.2
-
35
-
-
33947304329
-
Effects of C-peptide on isolated human pancreatic islet cells
-
Bugliani M, Torri S, Lupi R, et al. Effects of C-peptide on isolated human pancreatic islet cells. Diabetes Metab Res Rev 2007; 23(3): 215-219.
-
(2007)
Diabetes Metab Res Rev
, vol.23
, Issue.3
, pp. 215-219
-
-
Bugliani, M.1
Torri, S.2
Lupi, R.3
-
36
-
-
33645469061
-
C-peptide signals via Galpha i to protect against TNF-alpha-mediated apoptosis of opossum kidney proximal tubular cells
-
Al-Rasheed NM, Willars GB, Brunskill NJ. C-peptide signals via Galpha i to protect against TNF-alpha-mediated apoptosis of opossum kidney proximal tubular cells. J Am Soc Nephrol 2006; 17(4): 986-995.
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.4
, pp. 986-995
-
-
Al-Rasheed, N.M.1
Willars, G.B.2
Brunskill, N.J.3
-
37
-
-
79955813312
-
C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock
-
Chima RS, LaMontagne T, Piraino G, Hake PW, Denenberg A, Zingarelli B. C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock. Am J Physiol Lung Cell Mol Physiol 2011; 300(5): L730-739.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, Issue.5
-
-
Chima, R.S.1
LaMontagne, T.2
Piraino, G.3
Hake, P.W.4
Denenberg, A.5
Zingarelli, B.6
-
38
-
-
0033746038
-
C-peptide inhibits leukocyte-endothelium interaction in the microcirculation during acute endothelial dysfunction
-
Scalia R, Coyle KM, Levine BJ, Booth G, Lefer AM. C-peptide inhibits leukocyte-endothelium interaction in the microcirculation during acute endothelial dysfunction. FASEB J 2000; 14(14): 2357-2364.
-
(2000)
FASEB J
, vol.14
, Issue.14
, pp. 2357-2364
-
-
Scalia, R.1
Coyle, K.M.2
Levine, B.J.3
Booth, G.4
Lefer, A.M.5
-
39
-
-
27744531448
-
Human proinsulin C-peptide prevents proliferation of rat aortic smooth muscle cells cultured in high-glucose conditions
-
Kobayashi Y, Naruse K, Hamada Y, et al. Human proinsulin C-peptide prevents proliferation of rat aortic smooth muscle cells cultured in high-glucose conditions. Diabetologia 2005; 48(11): 2396-2401.
-
(2005)
Diabetologia
, vol.48
, Issue.11
, pp. 2396-2401
-
-
Kobayashi, Y.1
Naruse, K.2
Hamada, Y.3
-
40
-
-
77955518344
-
Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein
-
Mughal RS, Scragg JL, Lister P, et al. Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein. Diabetologia 2010; 53(8): 1761-1771.
-
(2010)
Diabetologia
, vol.53
, Issue.8
, pp. 1761-1771
-
-
Mughal, R.S.1
Scragg, J.L.2
Lister, P.3
-
41
-
-
48149106096
-
Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kappa B activation in vascular smooth muscle cells
-
Cifarelli V, Luppi P, Tse HM, He J, Piganelli J, Trucco M. Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kappa B activation in vascular smooth muscle cells. Atherosclerosis 2008; 201(2): 248-257.
-
(2008)
Atherosclerosis
, vol.201
, Issue.2
, pp. 248-257
-
-
Cifarelli, V.1
Luppi, P.2
Tse, H.M.3
He, J.4
Piganelli, J.5
Trucco, M.6
-
42
-
-
33751319145
-
C-Peptide induces vascular smooth muscle cell proliferation: involvement of SRC-kinase, phosphatidylinositol 3-kinase, and extracellular signal-regulated kinase 1/2
-
Walcher D, Babiak C, Poletek P, et al. C-Peptide induces vascular smooth muscle cell proliferation: involvement of SRC-kinase, phosphatidylinositol 3-kinase, and extracellular signal-regulated kinase 1/2. Circ Res 2006; 99(11): 1181-1187.
-
(2006)
Circ Res
, vol.99
, Issue.11
, pp. 1181-1187
-
-
Walcher, D.1
Babiak, C.2
Poletek, P.3
-
43
-
-
84857631025
-
C-peptide reduces pro-inflammatory cytokine secretion in LPS-stimulated U937 monocytes in condition of hyperglycemia
-
Haidet J, Cifarelli V, Trucco M, Luppi P. C-peptide reduces pro-inflammatory cytokine secretion in LPS-stimulated U937 monocytes in condition of hyperglycemia. Inflamm Res 2012; 61(1): 27-35.
-
(2012)
Inflamm Res
, vol.61
, Issue.1
, pp. 27-35
-
-
Haidet, J.1
Cifarelli, V.2
Trucco, M.3
Luppi, P.4
-
44
-
-
0348107405
-
Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar rats
-
Kitamura T, Kimura K, Makondo K, et al. Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar rats. Diabetologia 2003; 46(12): 1698-1705.
-
(2003)
Diabetologia
, vol.46
, Issue.12
, pp. 1698-1705
-
-
Kitamura, T.1
Kimura, K.2
Makondo, K.3
-
45
-
-
0013336206
-
Effects of proinsulin C-peptide on nitric oxide, microvascular blood flow and erythrocyte Na+,K+-ATPase activity in diabetes mellitus type I
-
Forst T, De La Tour DD, Kunt T, et al. Effects of proinsulin C-peptide on nitric oxide, microvascular blood flow and erythrocyte Na+, K+-ATPase activity in diabetes mellitus type I. Clin Sci (Lond) 2000; 98(3): 283-290.
-
(2000)
Clin Sci (Lond)
, vol.98
, Issue.3
, pp. 283-290
-
-
Forst, T.1
De La Tour, D.D.2
Kunt, T.3
-
46
-
-
82655179949
-
C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells
-
Galuska D, Pirkmajer S, Barres R, Ekberg K, Wahren J, Chibalin AV. C-peptide increases Na, K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells. PLoS One 2011; 6(12): e28294.
-
(2011)
PLoS One
, vol.6
, Issue.12
-
-
Galuska, D.1
Pirkmajer, S.2
Barres, R.3
Ekberg, K.4
Wahren, J.5
Chibalin, A.V.6
-
47
-
-
0034790670
-
Effects of C-peptide on glomerular and renal size and renal function in diabetic rats
-
Samnegård B, Jacobson SH, Jaremko G, Johansson BL, Sjöquist M. Effects of C-peptide on glomerular and renal size and renal function in diabetic rats. Kidney Int 2001; 60(4): 1258-1265.
-
(2001)
Kidney Int
, vol.60
, Issue.4
, pp. 1258-1265
-
-
Samnegård, B.1
Jacobson, S.H.2
Jaremko, G.3
Johansson, B.L.4
Sjöquist, M.5
-
48
-
-
40449084759
-
Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism
-
Nordquist L, Lai EY, Sjöquist M, Patzak A, Persson AE. Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism. Am J Physiol Regul Integr Comp Physiol 2008; 294(3): R836-841.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
, Issue.3
-
-
Nordquist, L.1
Lai, E.Y.2
Sjöquist, M.3
Patzak, A.4
Persson, A.E.5
-
49
-
-
44949174161
-
Proinsulin C-peptide abrogates type-1 diabetes-induced increase of renal endothelial nitric oxide synthase in rats
-
Kamikawa A, Ishii T, Shimada K, et al. Proinsulin C-peptide abrogates type-1 diabetes-induced increase of renal endothelial nitric oxide synthase in rats. Diabetes Metab Res Rev 2008; 24(4): 331-338.
-
(2008)
Diabetes Metab Res Rev
, vol.24
, Issue.4
, pp. 331-338
-
-
Kamikawa, A.1
Ishii, T.2
Shimada, K.3
-
50
-
-
77952334871
-
Proinsulin C-peptide prevents type-1 diabetes-induced decrease of renal Na+-K+-ATPase alpha1-subunit in rats
-
Nordquist L, Shimada K, Ishii T, Furuya DT, Kamikawa A, Kimura K. Proinsulin C-peptide prevents type-1 diabetes-induced decrease of renal Na+-K+-ATPase alpha1-subunit in rats. Diabetes Metab Res Rev 2010; 26(3): 193-199.
-
(2010)
Diabetes Metab Res Rev
, vol.26
, Issue.3
, pp. 193-199
-
-
Nordquist, L.1
Shimada, K.2
Ishii, T.3
Furuya, D.T.4
Kamikawa, A.5
Kimura, K.6
-
51
-
-
70350705959
-
Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption
-
Nordquist L, Brown R, Fasching A, Persson P, Palm F. Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption. Am J Physiol Renal Physiol 2009; 297(5): F1265-1272.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, Issue.5
-
-
Nordquist, L.1
Brown, R.2
Fasching, A.3
Persson, P.4
Palm, F.5
-
52
-
-
0038497913
-
Effects of proinsulin C-peptide in experimental diabetic neuropathy: vascular actions and modulation by nitric oxide synthase inhibition
-
Cotter MA, Ekberg K, Wahren J, Cameron NE. Effects of proinsulin C-peptide in experimental diabetic neuropathy: vascular actions and modulation by nitric oxide synthase inhibition. Diabetes 2003; 52(7): 1812-1817.
-
(2003)
Diabetes
, vol.52
, Issue.7
, pp. 1812-1817
-
-
Cotter, M.A.1
Ekberg, K.2
Wahren, J.3
Cameron, N.E.4
-
53
-
-
4143066829
-
C-peptide corrects endoneurial blood flow but not oxidative stress in type 1 BB/Wor rats
-
Stevens MJ, Zhang W, Li F, Sima AA. C-peptide corrects endoneurial blood flow but not oxidative stress in type 1 BB/Wor rats. Am J Physiol Endocrinol Metab 2004; 287(3): E497-505.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
, Issue.3
-
-
Stevens, M.J.1
Zhang, W.2
Li, F.3
Sima, A.A.4
-
54
-
-
61849139579
-
Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic patients
-
Panero F, Novelli G, Zucco C, et al. Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic patients. Diabetes Care 2009; 32(2): 301-305.
-
(2009)
Diabetes Care
, vol.32
, Issue.2
, pp. 301-305
-
-
Panero, F.1
Novelli, G.2
Zucco, C.3
-
55
-
-
0032499911
-
Reversal of lesions of diabetic nephropathy after pancreas transplantation
-
Fioretto P, Steffes MW, Sutherland DE, Goetz FC, Mauer M. Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med 1998; 339(2): 69-75.
-
(1998)
N Engl J Med
, vol.339
, Issue.2
, pp. 69-75
-
-
Fioretto, P.1
Steffes, M.W.2
Sutherland, D.E.3
Goetz, F.C.4
Mauer, M.5
-
56
-
-
0003453248
-
Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus
-
Johansson BL, Borg K, Fernqvist-Forbes E, Kernell A, Odergren T, Wahren J. Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus. Diabet Med 2000; 17(3): 181-189.
-
(2000)
Diabet Med
, vol.17
, Issue.3
, pp. 181-189
-
-
Johansson, B.L.1
Borg, K.2
Fernqvist-Forbes, E.3
Kernell, A.4
Odergren, T.5
Wahren, J.6
-
57
-
-
0037321440
-
Amelioration of sensory nerve dysfunction by C-peptide in patients with type 1 diabetes
-
Ekberg K, Brismar T, Johansson BL, Jonsson B, Lindstrom P, Wahren J. Amelioration of sensory nerve dysfunction by C-peptide in patients with type 1 diabetes. Diabetes 2003; 52(2): 536-541.
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 536-541
-
-
Ekberg, K.1
Brismar, T.2
Johansson, B.L.3
Jonsson, B.4
Lindstrom, P.5
Wahren, J.6
-
58
-
-
33846075220
-
C-peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
-
Ekberg K, Brismar T, Johansson BL, et al. C-peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy. Diabetes Care 2007; 30(1): 71-76.
-
(2007)
Diabetes Care
, vol.30
, Issue.1
, pp. 71-76
-
-
Ekberg, K.1
Brismar, T.2
Johansson, B.L.3
-
59
-
-
77956584167
-
Targeting beta-cell function early in the course of therapy for type 2 diabetes mellitus
-
Leahy JL, Hirsch IB, Peterson KA, Schneider D. Targeting beta-cell function early in the course of therapy for type 2 diabetes mellitus. J Clin Endocrinol Metab 2010; 95(9): 4206-4216.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, Issue.9
, pp. 4206-4216
-
-
Leahy, J.L.1
Hirsch, I.B.2
Peterson, K.A.3
Schneider, D.4
-
60
-
-
84862866404
-
Association between serum C-peptide levels and chronic microvascular complications in Korean type 2 diabetic patients
-
Kim BY, Jung CH, Mok JO, Kang SK, Kim CH. Association between serum C-peptide levels and chronic microvascular complications in Korean type 2 diabetic patients. Acta Diabetol 2012; 49(1): 9-15.
-
(2012)
Acta Diabetol
, vol.49
, Issue.1
, pp. 9-15
-
-
Kim, B.Y.1
Jung, C.H.2
Mok, J.O.3
Kang, S.K.4
Kim, C.H.5
-
61
-
-
0036517850
-
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression
-
Joussen AM, Poulaki V, Mitsiades N, et al. Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression. FASEB J 2002; 16(3): 438-440.
-
(2002)
FASEB J
, vol.16
, Issue.3
, pp. 438-440
-
-
Joussen, A.M.1
Poulaki, V.2
Mitsiades, N.3
-
62
-
-
36248953302
-
Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats
-
Moriwaki Y, Inokuchi T, Yamamoto A, et al. Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Acta Diabetol 2007; 44(4): 215-218.
-
(2007)
Acta Diabetol
, vol.44
, Issue.4
, pp. 215-218
-
-
Moriwaki, Y.1
Inokuchi, T.2
Yamamoto, A.3
-
63
-
-
30744471644
-
Thiazolidinediones: beyond glycemic control
-
Reynolds K, Goldberg RB. Thiazolidinediones: beyond glycemic control. Treat Endocrinol 2006; 5(1): 25-36.
-
(2006)
Treat Endocrinol
, vol.5
, Issue.1
, pp. 25-36
-
-
Reynolds, K.1
Goldberg, R.B.2
-
64
-
-
50649089597
-
Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease
-
Staels B, Maes M, Zambon A. Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease. Nat Clin Pract Cardiovasc Med 2008; 5(9): 542-553.
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, Issue.9
, pp. 542-553
-
-
Staels, B.1
Maes, M.2
Zambon, A.3
-
65
-
-
84887609239
-
Pharmacokinetics, safety, and tolerability of a long-acting C-peptide (CBX129801) in patients with type 1 diabetes
-
Foyt H, Daniels M, Milad M, Wahren J. Pharmacokinetics, safety, and tolerability of a long-acting C-peptide (CBX129801) in patients with type 1 diabetes. Diabetologia 2012; 55(Suppl 1): S455.
-
(2012)
Diabetologia
, vol.55
, Issue.SUPPL 1
-
-
Foyt, H.1
Daniels, M.2
Milad, M.3
Wahren, J.4
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