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Volumn 297, Issue 5, 2009, Pages

Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption

Author keywords

Diabetes mellitus; Oxygen consumption; Sodium excretion

Indexed keywords

C PEPTIDE; SODIUM ION;

EID: 70350705959     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00228.2009     Document Type: Article
Times cited : (52)

References (60)
  • 2
    • 3142679476 scopus 로고    scopus 로고
    • Potent activation of multiple signalling pathways by C-peptide in opossum kidney proximal tubular cells
    • Al-Rasheed NM, Meakin F, Royal EL, Lewington AJ, Brown J, Willars GB, Brunskill NJ. Potent activation of multiple signalling pathways by C-peptide in opossum kidney proximal tubular cells. Diabetologia 47: 987-997, 2004. (Pubitemid 38918157)
    • (2004) Diabetologia , vol.47 , Issue.6 , pp. 987-997
    • Al-Rasheed, N.M.1    Meakin, F.2    Royal, E.L.3    Lewington, A.J.4    Brown, J.5    Willars, G.B.6    Brunskill, N.J.7
  • 3
    • 0015014659 scopus 로고
    • Postglomerular vascular protein concentration: Evidence for a causal role in governing fluid reabsorption and glomerulotublar balance by the renal proximal tubule
    • Brenner BM, Troy JL. Postglomerular vascular protein concentration: evidence for a causal role in governing fluid reabsorption and glomerulotublar balance by the renal proximal tubule. J Clin Invest 50: 336-349, 1971.
    • (1971) J Clin Invest , vol.50 , pp. 336-349
    • Brenner, B.M.1    Troy, J.L.2
  • 4
    • 70350739003 scopus 로고
    • The relation between oxygen consumption and transport of sodium in the human kidney
    • Brodwall EK, Laake H. The relation between oxygen consumption and transport of sodium in the human kidney. Scand J Clin Lab Invest 16: 281-286, 1964.
    • (1964) Scand J Clin Lab Invest , vol.16 , pp. 281-286
    • Brodwall, E.K.1    Laake, H.2
  • 5
    • 0026523129 scopus 로고
    • +-ATPase in control and streptozotocin-induced diabetic mice by G-protein acting toxins and phorbol esters
    • +-ATPase in control and streptozotocin-induced diabetic mice by G-protein acting toxins and phorbol esters. Eur J Pharmacol 225: 275-279, 1992.
    • (1992) Eur J Pharmacol , vol.225 , pp. 275-279
    • Chen, C.C.1
  • 7
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-986, 1993.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 8
    • 0034235553 scopus 로고    scopus 로고
    • The effects ex vivo and in vitro of insulin and C-peptide on Na/K adenosine triphosphatase activity in red blood cell membranes of type 1 diabetic patients
    • DOI 10.1053/meta.2000.6753
    • Djemli-Shipkolye A, Gallice P, Coste T, Jannot MF, Tsimaratos M, Raccah D, Vague P. The effects ex vivo and in vitro of insulin and C-peptide on Na/K adenosine triphosphatase activity in red blood cell membranes of type 1 diabetic patients. Metabolism 49: 868-872, 2000. (Pubitemid 30483439)
    • (2000) Metabolism: Clinical and Experimental , vol.49 , Issue.7 , pp. 868-872
    • Djemli-Shipkolye, A.1    Gallice, P.2    Coste, T.3    Jannot, M.F.4    Tsimaratos, M.5    Raccah, D.6    Vague, P.7
  • 9
    • 33846934707 scopus 로고    scopus 로고
    • Early changes with diabetes in renal medullary hemodynamics as evaluated by fiberoptic probes and BOLD magnetic resonance imaging
    • dos Santos EA, Li LP, Ji L, Prasad PV. Early changes with diabetes in renal medullary hemodynamics as evaluated by fiberoptic probes and BOLD magnetic resonance imaging. Invest Radiol 42: 157-162, 2007.
    • (2007) Invest Radiol , vol.42 , pp. 157-162
    • Dos Santos, E.A.1    Li, L.P.2    Ji, L.3    Prasad, P.V.4
  • 16
    • 0036139915 scopus 로고    scopus 로고
    • Human C-peptide acutely lowers glomerular hyperfiltration and proteinuria in diabetic rats: A dose-response study
    • DOI 10.1007/s00210-001-0502-1
    • Huang DY, Richter K, Breidenbach A, Vallon V. Human C-peptide acutely lowers glomerular hyperfiltration and proteinuria in diabetic rats: a dose-response study. Naunyn Schmiedebergs Arch Pharmacol 365: 67-73, 2002. (Pubitemid 34045241)
    • (2002) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.365 , Issue.1 , pp. 67-73
    • Huang, D.-Y.1    Richter, K.2    Breidenbach, A.3    Vallon, V.4
  • 19
    • 0003453248 scopus 로고    scopus 로고
    • Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus
    • DOI 10.1046/j.1464-5491.2000.00274.x
    • Johansson BL, Borg K, Fernqvist-Forbes E, Kernell A, Odergren T, Wahren J. Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with type 1 diabetes mellitus. Diabet Med 17: 181-189, 2000. (Pubitemid 30212289)
    • (2000) Diabetic Medicine , vol.17 , Issue.3 , pp. 181-189
    • Johansson, B.-L.1    Borg, K.2    Fernqvist-Forbes, E.3    Kernell, A.4    Odergren, T.5    Wahren, J.6
  • 20
    • 0026558822 scopus 로고
    • The influence of human C-peptide on renal function and glucose utilization in type 1 (insulin-dependent) diabetic patients
    • Johansson BL, Sjoberg S, Wahren J. The influence of human C-peptide on renal function and glucose utilization in type 1 (insulin-dependent) diabetic patients. Diabetologia 35: 121-128, 1992.
    • (1992) Diabetologia , vol.35 , pp. 121-128
    • Johansson, B.L.1    Sjoberg, S.2    Wahren, J.3
  • 23
    • 33646358954 scopus 로고    scopus 로고
    • High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway
    • DOI 10.1681/ASN.2005090918
    • Katavetin P, Miyata T, Inagi R, Tanaka T, Sassa R, Ingelfinger JR, Fujita T, Nangaku M. High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway. J Am Soc Nephrol 17: 1405-1413, 2006. (Pubitemid 43673421)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.5 , pp. 1405-1413
    • Katavetin, P.1    Miyata, T.2    Inagi, R.3    Tanaka, T.4    Sassa, R.5    Ingelfinger, J.R.6    Fujita, T.7    Nangaku, M.8
  • 24
    • 0014189489 scopus 로고
    • The role of sodium-potassium-activated adenosine triphosphatase in the reabsorption of sodium by the kidney
    • Katz AI, Epstein FH. The role of sodium-potassium-activated adenosine triphosphatase in the reabsorption of sodium by the kidney. J Clin Invest 46: 1999-2011, 1967.
    • (1967) J Clin Invest , vol.46 , pp. 1999-2011
    • Katz, A.I.1    Epstein, F.H.2
  • 26
    • 0348107405 scopus 로고    scopus 로고
    • Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar rats
    • DOI 10.1007/s00125-003-1232-3
    • Kitamura T, Kimura K, Makondo K, Furuya DT, Suzuki M, Yoshida T, Saito M. Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar rats. Diabetologia 46: 1698-1705, 2003. (Pubitemid 38005332)
    • (2003) Diabetologia , vol.46 , Issue.12 , pp. 1698-1705
    • Kitamura, T.1    Kimura, K.2    Makondo, K.3    Furuya, D.T.4    Suzuki, M.5    Yoshida, T.6    Saito, M.7
  • 27
    • 0028216159 scopus 로고
    • Increased renal metabolism in diabetes: Mechanism and functional implications
    • Korner A, Eklof AC, Celsi G, Aperia A. Increased renal metabolism in diabetes. Mechanism and functional implications. Diabetes 43: 629-633, 1994. (Pubitemid 24138773)
    • (1994) Diabetes , vol.43 , Issue.5 , pp. 629-633
    • Korner, A.1    Eklof, A.-C.2    Celsi, G.3    Aperia, A.4
  • 28
    • 0022519977 scopus 로고
    • Development of renal hypertrophy and increased renal Na,K-ATPase in streptozotocin-diabetic rats
    • Ku DD, Sellers BM, Meezan E. Development of renal hypertrophy and increased renal Na,K-ATPase in streptozotocin-diabetic rats. Endocrinology 119: 672-679, 1986. (Pubitemid 16048823)
    • (1986) Endocrinology , vol.119 , Issue.2 , pp. 672-679
    • Ku, D.D.1    Sellers, B.M.2    Meezan, E.3
  • 29
    • 33744806361 scopus 로고    scopus 로고
    • Fluid transport and ion fluxes in mammalian kidney proximal tubule: A model analysis of isotonic transport
    • DOI 10.1111/j.1748-1716.2006.01580.x
    • Larsen EH, Mobjerg N, Sorensen JN. Fluid transport and ion fluxes in mammalian kidney proximal tubule: a model analysis of isotonic transport. Acta Physiol (Oxf) 187: 177-189, 2006. (Pubitemid 43828775)
    • (2006) Acta Physiologica , vol.187 , Issue.1-2 , pp. 177-189
    • Larsen, E.H.1    Mobjerg, N.2    Sorensen, J.N.3
  • 30
    • 1442341043 scopus 로고
    • Dependence of glomerular filtration rate on proximal tubular reabsorption of salt
    • Leyssac PP. Dependence of glomerular filtration rate on proximal tubular reabsorption of salt. Acta Physiol Scand 58: 236-242, 1963.
    • (1963) Acta Physiol Scand , vol.58 , pp. 236-242
    • Leyssac, P.P.1
  • 31
    • 0022973258 scopus 로고
    • Atrial natriuretic peptide causes pre-glomerular vasodilation and post-glomerular vasoconstriction in rat kidney
    • DOI 10.1038/324473a0
    • Marin-Grez M, Fleming JT, Steinhausen M. Atrial natriuretic peptide causes pre-glomerular vasodilatation and post-glomerular vasoconstriction in rat kidney. Nature 324: 473-476, 1986. (Pubitemid 17184166)
    • (1986) Nature , vol.324 , Issue.6096 , pp. 473-476
    • Marin-Grez, M.1    Fleming, J.T.2    Steinhausen, M.3
  • 33
    • 0023013773 scopus 로고
    • Dietary protein restriction in established renal injury in the rat. Selective role of glomerular capillary pressure in progressive glomerular dysfunction
    • Nath KA, Kren SM, Hostetter TH. Dietary protein restriction in established renal injury in the rat. Selective role of glomerular capillary pressure in progressive glomerular dysfunction. J Clin Invest 78: 1199-1205, 1986.
    • (1986) J Clin Invest , vol.78 , pp. 1199-1205
    • Nath, K.A.1    Kren, S.M.2    Hostetter, T.H.3
  • 34
    • 0025604929 scopus 로고
    • +)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration
    • +)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration. Biochem Pharmacol 40: 2611-2616, 1990.
    • (1990) Biochem Pharmacol , vol.40 , pp. 2611-2616
    • Noel, F.1    Fagoo, M.2    Godfraind, T.3
  • 36
    • 34447624323 scopus 로고    scopus 로고
    • The C-peptide fragment EVARQ reduces glomerular hyperfiltration in streptozotocin-induced diabetic rats
    • DOI 10.1002/dmrr.704
    • Nordquist L, Moe E, Sjoquist M. The C-peptide fragment EVARQ reduces glomerular hyperfiltration in streptozotocin-induced diabetic rats. Diabetes Metab Res Rev 23: 400-405, 2007. (Pubitemid 47091244)
    • (2007) Diabetes/Metabolism Research and Reviews , vol.23 , Issue.5 , pp. 400-405
    • Nordquist, L.1    Moe, E.2    Sjoquist, M.3
  • 39
    • 0042879795 scopus 로고    scopus 로고
    • Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension
    • DOI 10.1007/s00125-003-1155-z
    • Palm F, Cederberg J, Hansell P, Liss P, Carlsson PO. Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension. Diabetologia 46: 1153-1160, 2003. (Pubitemid 37041246)
    • (2003) Diabetologia , vol.46 , Issue.8 , pp. 1153-1160
    • Palm, F.1    Cederberg, J.2    Hansell, P.3    Liss, P.4    Carlsson, P.-O.5
  • 40
    • 4143078293 scopus 로고    scopus 로고
    • Polyol-pathway-dependent disturbances in renal medullary metabolism in experimental insulin-deficient diabetes mellitus in rats
    • Palm F, Hansell P, Ronquist G, Waldenstrom A, Liss P, Carlsson PO. Polyol-pathway-dependent disturbances in renal medullary metabolism in experimental insulin-deficient diabetes mellitus in rats. Diabetologia 47: 1223-1231, 2004. (Pubitemid 39093318)
    • (2004) Diabetologia , vol.47 , Issue.7 , pp. 1223-1231
    • Palm, F.1    Hansell, P.2    Ronquist, G.3    Waldenstrom, A.4    Liss, P.5    Carlsson, P.-O.6
  • 43
    • 0034773496 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide synthase in the macula densa
    • DOI 10.1046/j.1523-1755.2001.00987.x
    • Ren YL, Garvin JL, Ito S, Carretero OA. Role of neuronal nitric oxide synthase in the macula densa. Kidney Int 60: 1676-1683, 2001. (Pubitemid 32999971)
    • (2001) Kidney International , vol.60 , Issue.5 , pp. 1676-1683
    • Ren, Y.1    Garvin, J.L.2    Ito, S.3    Carretero, O.A.4
  • 48
    • 0034790670 scopus 로고    scopus 로고
    • Effects of C-peptide on glomerular and renal size and renal function in diabetic rats
    • DOI 10.1046/j.1523-1755.2001.00964.x
    • Samnegard B, Jacobson SH, Jaremko G, Johansson BL, Sjoquist M. Effects of C-peptide on glomerular and renal size and renal function in diabetic rats. Kidney Int 60: 1258-1265, 2001. (Pubitemid 32960021)
    • (2001) Kidney International , vol.60 , Issue.4 , pp. 1258-1265
    • Samnegard, B.1    Jacobson, S.H.2    Jaremko, G.3    Johansson, B.-L.4    Sjoquist, M.5
  • 50
    • 0033778096 scopus 로고    scopus 로고
    • Renal Na-K-ATPase hyperactivity in diabetic Psammomys obesus is related to glomerular hyperfiltration but is insulin-independent
    • Scherzer P, Nachliel I, Bar-On H, Popovtzer MM, Ziv E. Renal Na-K-ATPase hyperactivity in diabetic Psammomys obesus is related to glomerular hyperfiltration but is insulin-independent. J Endocrinol 167: 347-354, 2000. (Pubitemid 30836626)
    • (2000) Journal of Endocrinology , vol.167 , Issue.2 , pp. 347-354
    • Scherzer, P.1    Nachliel, I.2    Bar-On, H.3    Popovtzer, M.M.4    Ziv, E.5
  • 51
    • 0031702795 scopus 로고    scopus 로고
    • Effects of C-peptide on renal function at the early stage of experimental diabetes
    • Sjoquist M, Huang W, Johansson BL. Effects of C-peptide on renal function at the early stage of experimental diabetes. Kidney Int 54: 758-764, 1998. (Pubitemid 28397393)
    • (1998) Kidney International , vol.54 , Issue.3 , pp. 758-764
    • Sjoquist, M.1    Huang, W.2    Johansson, B.-L.3
  • 52
    • 0002562033 scopus 로고
    • Sodium transport and oxygen consumption in the mammalian kidney
    • Thaysen JH, Lassen NA, Munck O. Sodium transport and oxygen consumption in the mammalian kidney. Nature 190: 919-921, 1961.
    • (1961) Nature , vol.190 , pp. 919-921
    • Thaysen, J.H.1    Lassen, N.A.2    Munck, O.3
  • 54
    • 0032707179 scopus 로고    scopus 로고
    • Glomerular hyperfiltration in experimental diabetes mellitus: Potential role of tubular reabsorption
    • Vallon V, Richter K, Blantz RC, Thomson S, Osswald H. Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption. J Am Soc Nephrol 10: 2569-2576, 1999.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2569-2576
    • Vallon, V.1    Richter, K.2    Blantz, R.C.3    Thomson, S.4    Osswald, H.5
  • 56
    • 18844383167 scopus 로고    scopus 로고
    • Glomerular hyperfiltration in type 1 diabetes mellitus results from primary changes in proximal tubular sodium handling without changes in volume expansion
    • DOI 10.1111/j.1365-2362.2005.01497.x
    • Vervoort G, Veldman B, Berden JH, Smits P, Wetzels JF. Glomerular hyperfiltration in type 1 diabetes mellitus results from primary changes in proximal tubular sodium handling without changes in volume expansion. Eur J Clin Invest 35: 330-336, 2005. (Pubitemid 40691281)
    • (2005) European Journal of Clinical Investigation , vol.35 , Issue.5 , pp. 330-336
    • Vervoort, G.1    Veldman, B.2    Berden, J.H.M.3    Smits, P.4    Wetzels, J.F.M.5


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