-
1
-
-
0019427092
-
Anewprognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
-
Binet JL, AuquierA, Dighiero G, et al. Anewprognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 1981;48:198-206.
-
(1981)
Cancer
, vol.48
, pp. 198-206
-
-
Binet, J.L.1
Auquier, A.2
Dighiero, G.3
-
2
-
-
0016740933
-
Clinical staging of chronic lymphocytic leukemia
-
Rai KR, Sawitsky A, Cronkite EP, et al. Clinical staging of chronic lymphocytic leukemia. Blood 1975;46:219-234.
-
(1975)
Blood
, vol.46
, pp. 219-234
-
-
Rai, K.R.1
Sawitsky, A.2
Cronkite, E.P.3
-
3
-
-
34547907101
-
Prognostic markers in chronic lymphocytic leukaemia
-
Hamblin TJ. Prognostic markers in chronic lymphocytic leukaemia. Best Pract Res Clin Haematol 2007;20:455-468.
-
(2007)
Best Pract Res Clin Haematol
, vol.20
, pp. 455-468
-
-
Hamblin, T.J.1
-
4
-
-
0022569746
-
Lymphocyte doubling time in chronic lymphocytic leukaemia: Analysis of its prognostic significance
-
Montserrat E, Sanchez-Bisono J, Vinolas N, et al. Lymphocyte doubling time in chronic lymphocytic leukaemia: Analysis of its prognostic significance. Br J Haematol 1986;62:567-575.
-
(1986)
Br J Haematol
, vol.62
, pp. 567-575
-
-
Montserrat, E.1
Sanchez-Bisono, J.2
Vinolas, N.3
-
5
-
-
45149100665
-
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
-
HallekM, Cheson BD, Catovsky D, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 2008;1 11:5446-5456.
-
(2008)
Blood
, vol.111
, pp. 5446-5456
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
-
6
-
-
0021744595
-
Serum LDH concentration in non-Hodgkin's lymphomas. Relationship to histologic type, tumor mass, and presentation features
-
Fasola G, Fanin R, Gherlinzoni F, et al. Serum LDH concentration in non-Hodgkin?s lymphomas. Relationship to histologic type, tumor mass, and presentation features. Acta Haematol 1984;72:231-238.
-
(1984)
Acta Haematol
, vol.72
, pp. 231-238
-
-
Fasola, G.1
Fanin, R.2
Gherlinzoni, F.3
-
7
-
-
0023092276
-
Prognosis of chronic lymphocytic leukemia: A multivariate regression analysis of 325 untreated patients
-
Lee JS, Dixon DO, ICantarjian HM, et al. Prognosis of chronic lymphocytic leukemia: A multivariate regression analysis of 325 untreated patients. Blood 1987;69:929-936.
-
(1987)
Blood
, vol.69
, pp. 929-936
-
-
Lee, J.S.1
Dixon, D.O.2
Icantarjian, H.M.3
-
8
-
-
47249117983
-
Biological and clinical risk factors of chronic lymphocytic leukaemia transformation to Richter syndrome
-
Rossi D, Cern M, Capello D, et al. Biological and clinical risk factors of chronic lymphocytic leukaemia transformation to Richter syndrome. Br J Haematol 2008;142:202-215.
-
(2008)
Br J Haematol
, vol.142
, pp. 202-215
-
-
Rossi, D.1
Cern, M.2
Capello, D.3
-
9
-
-
0029829395
-
Serum beta(2)-microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukemia and immunocytoma
-
Hallek M, Wanders L, Ostwald M, et al. Serum beta(2)-microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukemia and immunocytoma. Leuk Lymphoma 1996;22:439-447.
-
(1996)
Leuk Lymphoma
, vol.22
, pp. 439-447
-
-
Hallek, M.1
Wanders, L.2
Ostwald, M.3
-
10
-
-
35748932373
-
Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in2 l26patients: 20 years of experience at theUniversity of Texas M.D. Anderson Cancer Center
-
Tsimberidou AM, Wen 5, O?Brien 5, et al. Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in2, l26patients: 20 years of experience at theUniversity of Texas M.D. Anderson Cancer Center. J din Oncol 2007;25:4648-4656.
-
(2007)
J Din Oncol
, vol.25
, pp. 4648-4656
-
-
Tsimberidou, A.M.1
Wen, S.2
Obrien, S.3
-
11
-
-
66749118874
-
Molica 5, Ferrarini M, Morabito e Predictive value of beta2-microglobulin (beta2-m) levels in chronic lymphocytic leukemia since Binet A stages
-
Gentile M, Cutrona G, Neri A, Molica 5, Ferrarini M, Morabito E Predictive value of beta2-microglobulin (beta2-m) levels in chronic lymphocytic leukemia since Binet A stages. Haematologica 2009; 94:887-888.
-
(2009)
Haematologica
, vol.94
, pp. 887-888
-
-
Gentile, M.1
Cutrona, G.2
Neri, A.3
-
12
-
-
0034986707
-
Retrospective study of the prognostic role of serum thymidine kinase level in CLL patients with active disease treated with iludarabine
-
Di Raimondo F, Giustolisi R, Lerner 5, et al. Retrospective study of the prognostic role of serum thymidine kinase level in CLL patients with active disease treated with iludarabine. Ann Oncol 200 1; 12 :621-625.
-
(2001)
Ann Oncol
, vol.12
, pp. 621-625
-
-
Di Raimondo, F.1
Giustolisi, R.2
Lerner, S.3
-
13
-
-
0037265679
-
Predictive value of serum thymidine kinase level for Ig-V mutational status in B-CLL
-
Magnac C, Porcher R, Davi F, et al. Predictive value of serum thymidine kinase level for Ig-V mutational status in B-CLL. Leukemia 2003; 17: 133-137.
-
(2003)
Leukemia
, vol.17
, pp. 133-137
-
-
Magnac, C.1
Porcher, R.2
Davi, F.3
-
14
-
-
33748354035
-
Serum TIC levels in CLL identify Binet stage A patients within biologically defined prognostic subgroups most likely to undergo disease progression
-
Matthews C, Catherwood MA, Morris TC, et al. Serum TIC levels in CLL identify Binet stage A patients within biologically defined prognostic subgroups most likely to undergo disease progression. Eur Haematol 2006;77:309-317.
-
(2006)
Eur Haematol
, vol.77
, pp. 309-317
-
-
Matthews, C.1
Catherwood, M.A.2
Morris, T.C.3
-
15
-
-
0033567968
-
Ig v gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
-
Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999;94:1840-1847.
-
(1999)
Blood
, vol.94
, pp. 1840-1847
-
-
Damle, R.N.1
Wasil, T.2
Fais, F.3
-
16
-
-
0033567907
-
Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
-
Hamblin TJ, Davis Z, Gardiner A, et al. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999;94:1848-1854.
-
(1999)
Blood
, vol.94
, pp. 1848-1854
-
-
Hamblin, T.J.1
Davis, Z.2
Gardiner, A.3
-
17
-
-
33845513520
-
ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia
-
Ghia P, Stamatopoulos IC, Belessi C, et al. ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia. Leukemia 2007;21:1-3.
-
(2007)
Leukemia
, vol.21
, pp. 1-3
-
-
Ghia, P.1
Stamatopoulos, I.C.2
Belessi, C.3
-
18
-
-
79958131059
-
Immunoglobulin sequence analysis and prognostication in CLL: Guidelines from the ERIC review board for reliable interpretation of problematic cases
-
Langerak AW, Day F, Ghia P, et al. Immunoglobulin sequence analysis and prognostication in CLL: Guidelines from the ERIC review board for reliable interpretation of problematic cases. Leukemia 201 1;25:979-984.
-
(2011)
Leukemia
, vol.25
, pp. 979-984
-
-
Langerak, A.W.1
Day, F.2
Ghia, P.3
-
19
-
-
0037103212
-
V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia
-
ICrober A, Seiler T, Benner A, et al. V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood 2002;100: 1410-1416.
-
(2002)
Blood
, vol.100
, pp. 1410-1416
-
-
Icrober, A.1
Seiler, T.2
Benner, A.3
-
20
-
-
0037103272
-
Relationship between p53 dysfunction,. CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia
-
Lin IC, Sherrington PD, Dennis M, et al. Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia. Blood 2002;100:1404-1409.
-
(2002)
Blood
, vol.100
, pp. 1404-1409
-
-
Lin, I.C.1
Sherrington, P.D.2
Dennis, M.3
-
21
-
-
0037103257
-
Multivariate analysis of prognostic factors in CLL: Clinical stage,IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors
-
Oscier DG, Gardiner AC, Mould SJ, et al. Multivariate analysis of prognostic factors in CLL: Clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 2002;100:1177-1184.
-
(2002)
Blood
, vol.100
, pp. 1177-1184
-
-
Oscier, D.G.1
Gardiner, A.C.2
Mould, S.J.3
-
22
-
-
17844365857
-
Patients with chronic lymphocytic leukemia with mutated VH genes presenting with Binet stage B or C form a subgroup with a poor outcome
-
Tobin G, Thunberg U, Laurell A, et al. Patients with chronic lymphocytic leukemia with mutated VH genes presenting with Binet stage B or C form a subgroup with a poor outcome. Haematologica 2005;90:465-469.
-
(2005)
Haematologica
, vol.90
, pp. 465-469
-
-
Tobin, G.1
Thunberg, U.2
Laurell, A.3
-
23
-
-
38349088322
-
Determination of how many immunoglobulin variable region heavy chain mutations are allowable in unmutated chronic lymphocytic leukaemia -long-term follow up of patients with different percentages of mutations
-
Hamblin TJ, Davis ZA, Oscier DG. Determination of how many immunoglobulin variable region heavy chain mutations are allowable in unmutated chronic lymphocytic leukaemia -long-term follow up of patients with different percentages of mutations. Br J Haematol 2008; 140:320-323
-
(2008)
Br J Haematol
, vol.140
, pp. 320-323
-
-
Hamblin, T.J.1
Davis, Z.A.2
Oscier, D.G.3
-
24
-
-
0037085801
-
Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia
-
Tobin G, Thunberg U, Johnson A, et al. Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia. Blood 2002;99:2262-2264.
-
(2002)
Blood
, vol.99
, pp. 2262-2264
-
-
Tobin, G.1
Thunberg, U.2
Johnson, A.3
-
25
-
-
33947598891
-
Comprehensive characterization of IGHV3-21-expressing B-Cell chronic lymphocytic leukemia: An Italian multicenter study
-
Bomben R, Dal Bo M, Capello D, et al. Comprehensive characterization of IGHV3-21-expressing B-Cell chronic lymphocytic leukemia: An Italian multicenter study. Blood 2007;109:2989-2998.
-
(2007)
Blood
, vol.109
, pp. 2989-2998
-
-
Bomben, R.1
Dal Bo, M.2
Capello, D.3
-
26
-
-
46749099871
-
Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection
-
Ghia EM, Jam 5, Widhopf GF 2nd, et al. Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. Blood 2008;111:5101-5108.
-
(2008)
Blood
, vol.111
, pp. 5101-5108
-
-
Ghia, E.M.1
Jam, S.2
Widhopf II, G.F.3
-
27
-
-
33645507226
-
Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
-
Thorselius M, Krober A, Murray F, et al. Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. Blood 2006;107:2889-2894.
-
(2006)
Blood
, vol.107
, pp. 2889-2894
-
-
Thorselius, M.1
Krober, A.2
Murray, F.3
-
28
-
-
10744230550
-
Chronic lymphocytic leukemiasutilizingtheVH3-21 gene displayhighlyrestrictedVlambda2-14 gene use and homologous CDR3s: Implicating recognition of a common antigen epitope
-
Tobin G, Thunberg U, Johnson A, et al. Chronic lymphocytic leukemiasutilizingtheVH3-21 gene displayhighlyrestrictedVlambda2-14 gene use and homologous CDR3s: Implicating recognition of a common antigen epitope. Blood 2003;101:4952-4957.
-
(2003)
Blood
, vol.101
, pp. 4952-4957
-
-
Tobin, G.1
Thunberg, U.2
Johnson, A.3
-
29
-
-
7244232709
-
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
-
Tobin G, Thunberg U, Karlsson K, et al. Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. Blood 2004;104:2879-2885.
-
(2004)
Blood
, vol.104
, pp. 2879-2885
-
-
Tobin, G.1
Thunberg, U.2
Karlsson, K.3
-
31
-
-
78649786581
-
Antigens in chronic lymphocytic leukemia-1mplications for cell origin and leukemogenesis
-
Rosen A, Murray F, Evaldsson C, Rosenquist R. Antigens in chronic lymphocytic leukemia-1mplications for cell origin and leukemogenesis. Semin Cancer Biol 2010;20:400-409.
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 400-409
-
-
Rosen, A.1
Murray, F.2
Evaldsson, C.3
Rosenquist, R.4
-
32
-
-
4344704897
-
Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
-
Messmer BY, Albesiano E, Efremov DG, et al. Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia. J Exp Med 2004;200:519-525.
-
(2004)
J Exp Med
, vol.200
, pp. 519-525
-
-
Messmer, B.Y.1
Albesiano, E.2
Efremov, D.G.3
-
33
-
-
33846108722
-
Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
-
Stamatopoulos K, Belessi C, Moreno C, et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations. Blood 2007;109: 259-270.
-
(2007)
Blood
, vol.109
, pp. 259-270
-
-
Stamatopoulos, K.1
Belessi, C.2
Moreno, C.3
-
34
-
-
84861033763
-
Stereotyped B-Cell receptors in one-third of chronic lymphocytic leukemia: A molecular classification with implications for targeted therapies
-
Agathangelidis A, Darzentas N, Hadzidimitriou A, et al. Stereotyped B-Cell receptors in one-third of chronic lymphocytic leukemia: A molecular classification with implications for targeted therapies. Blood 2012;119:4467-4475.
-
(2012)
Blood
, vol.119
, pp. 4467-4475
-
-
Agathangelidis, A.1
Darzentas, N.2
Hadzidimitriou, A.3
-
35
-
-
58549100059
-
Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: Results from an Italian multicentre study
-
Bomben R, Dal Bo M, Capello D, et al. Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: Results from an Italian multicentre study. Br J Haematol 2009; 144:492-506.
-
(2009)
Br J Haematol
, vol.144
, pp. 492-506
-
-
Bomben, R.1
Dal Bo, M.2
Capello, D.3
-
36
-
-
13544275555
-
Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: The lesson of the IGHV3-21 gene
-
Ghia P, Stamatopoulos K, Belessi C, et al. Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: The lesson of the IGHV3-21 gene. Blood 2005; 105:1678-1685.
-
(2005)
Blood
, vol.105
, pp. 1678-1685
-
-
Ghia, P.1
Stamatopoulos, K.2
Belessi, C.3
-
37
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
Dohner H, Stilgenbauer 5, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000; 343:1910-1916.
-
(2000)
N Engl J Med
, vol.343
, pp. 1910-1916
-
-
Dohner, H.1
Stilgenbauer, S.2
Benner, A.3
-
38
-
-
84880262505
-
Exploring the genetic landscape in chronic lymphocytic leukemia using high-resolution technologies
-
2013 Feb 28
-
Gunnarsson R, Mansouri L, Rosenquist R. Exploring the genetic landscape in chronic lymphocytic leukemia using high-resolution technologies. Leuk Lymphoma 2013 Feb 28.
-
Leuk Lymphoma
-
-
Gunnarsson, R.1
Mansouri, L.2
Rosenquist, R.3
-
39
-
-
84874428346
-
Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia
-
Rossi D, Rasi 5, Spina V, et al. Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia. Blood 2013;121:1403-1412.
-
(2013)
Blood
, vol.121
, pp. 1403-1412
-
-
Rossi, D.1
Rasi, S.2
Spina, V.3
-
40
-
-
72949093335
-
From pathogenesis to treatment of chronic lymphocytic leukaemia
-
Zenz I, Mertens D, Kuppers R, et al. From pathogenesis to treatment of chronic lymphocytic leukaemia. Nat Rev Cancer 2010;10:37-50.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 37-50
-
-
Zenz, I.1
Mertens, D.2
Kuppers, R.3
-
41
-
-
84863778287
-
ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia
-
Pospisilova 5, Gonzalez D, Malcikova J, et al. ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia. Leukemia 2012;26:1458-1461.
-
(2012)
Leukemia
, vol.26
, pp. 1458-1461
-
-
Pospisilova, S.1
Gonzalez, D.2
Malcikova, J.3
-
42
-
-
74249084263
-
Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: A high-resolution genomic screening of newly diagnosed patients
-
Gunnarsson R, Isaksson A, Mansouri M, et al. Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: A high-resolution genomic screening of newly diagnosed patients. Leukemia 2010;24:211-215.
-
(2010)
Leukemia
, vol.24
, pp. 211-215
-
-
Gunnarsson, R.1
Isaksson, A.2
Mansouri, M.3
-
43
-
-
36348953152
-
Comprehensive genetic characterization of CLL: A study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping
-
Haferlach C, Dicker F, Schnittger 5, et al. Comprehensive genetic characterization of CLL: A study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping. Leukemia 2007;21:2442-2451.
-
(2007)
Leukemia
, vol.21
, pp. 2442-2451
-
-
Haferlach, C.1
Dicker, F.2
Schnittger, S.3
-
44
-
-
52649091186
-
Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia
-
Kujawski L, Ouillette P, Erba H, et al. Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. Blood 2008;112:1993-2003.
-
(2008)
Blood
, vol.112
, pp. 1993-2003
-
-
Kujawski, L.1
Ouillette, P.2
Erba, H.3
-
45
-
-
30444451801
-
Chromosomaltranslocations are associated with poor prognosis in chronic lymphocytic leukemia
-
Mayrc, SpeicherMR, KoflerDM, etal. Chromosomaltranslocations are associated with poor prognosis in chronic lymphocytic leukemia. Blood 2006;107:742-751.
-
(2006)
Blood
, vol.107
, pp. 742-751
-
-
Mayrc Speicher, M.R.1
Kofler, D.M.2
-
46
-
-
34447637276
-
Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-Cell chronic lymphocytic leukemia patients treated with cladribine
-
Van Den Neste E, Robin V, Francart J, et al. Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-Cell chronic lymphocytic leukemia patients treated with cladribine. Leukemia 2007;21:1715-1722.
-
(2007)
Leukemia
, vol.21
, pp. 1715-1722
-
-
Van Den Neste, E.1
Robin, V.2
Francart, J.3
-
47
-
-
79960353160
-
Analysis of the chronic lymphocytic leukemia coding genome: Role ofNOTCH1 mutational activation
-
Fabbri G, Rasi 5, Rossi D, et al. Analysis of the chronic lymphocytic leukemia coding genome: Role ofNOTCH1 mutational activation. J Exp Med 2011;208:1389-1401.
-
(2011)
J Exp Med
, vol.208
, pp. 1389-1401
-
-
Fabbri, G.1
Rasi, S.2
Rossi, D.3
-
48
-
-
79960036578
-
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
-
Puente XS, Pinyol M, QuesadaV, et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 2011;475:101-105.
-
(2011)
Nature
, vol.475
, pp. 101-105
-
-
Puente, X.S.1
Pinyol, M.2
Quesada, V.3
-
49
-
-
84555171449
-
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
-
Quesada V Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet 2012;44:47-52.
-
(2012)
Nat Genet
, vol.44
, pp. 47-52
-
-
Quesada, V.1
Conde, L.2
Villamor, N.3
-
50
-
-
84858859064
-
Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
-
Rossi D, Fangazio M, Rasi 5, et al. Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia. Blood 2012;1 19:2854-2862.
-
(2012)
Blood
, vol.119
, pp. 2854-2862
-
-
Rossi, D.1
Fangazio, M.2
Rasi, S.3
-
51
-
-
84855370035
-
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
-
Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011; 365:2497-2506.
-
(2011)
N Engl J Med
, vol.365
, pp. 2497-2506
-
-
Wang, L.1
Lawrence, M.S.2
Wan, Y.3
-
52
-
-
84873567287
-
NOTCH 1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia
-
Mansouri L, Cahill N, Gunnarsson R, et al. NOTCH 1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia. Leukemia 2013;27:5 12-514.
-
(2013)
Leukemia
, vol.27
, pp. 512-514
-
-
Mansouri, L.1
Cahill, N.2
Gunnarsson, R.3
-
53
-
-
0025112785
-
Prognostic subgroups in B-Cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities
-
Juliusson G, Oscier DG, Fitchett M, et al. Prognostic subgroups in B-Cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. N Engl J Med 1990;323:720-724.
-
(1990)
N Engl J Med
, vol.323
, pp. 720-724
-
-
Juliusson, G.1
Oscier, D.G.2
Fitchett, M.3
-
54
-
-
79961059215
-
Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
-
Gunnarsson R, MansouriL, IsakssonA, et al. Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia. Haematologica 2011;96:1161-1169.
-
(2011)
Haematologica
, vol.96
, pp. 1161-1169
-
-
Gunnarsson, R.1
Isakssona, M.2
-
55
-
-
0029969111
-
Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders
-
Stilgenbauer 5, Liebisch P, James MR, et al. Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders. Proc Natl Acad Sci USA 1996;93:1 1837-11841.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11837-11841
-
-
Stilgenbauer, S.1
Liebisch, P.2
James, M.R.3
-
56
-
-
0030051855
-
Leukemia and lymphoma in ataxia telangiectasia
-
Taylor AM, Metcalfe TA, Thick J, et al. Leukemia and lymphoma in ataxia telangiectasia. Blood 1996;87:423-438.
-
(1996)
Blood
, vol.87
, pp. 423-438
-
-
Taylor, A.M.1
Metcalfe, T.A.2
Thick, J.3
-
57
-
-
27644450586
-
Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL
-
Austen B, Powell JE, Alvi A, et al. Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL. Blood 2005;106:3175-3182.
-
(2005)
Blood
, vol.106
, pp. 3175-3182
-
-
Austen, B.1
Powell, J.E.2
Alvi, A.3
-
58
-
-
0032944319
-
ATM mutations in B-Cell chronic lymphocytic leukemia
-
Bullrich F, Rasio D, Kitada 5, et al. ATM mutations in B-Cell chronic lymphocytic leukemia. Cancer Res 1999;59:24-27.
-
(1999)
Cancer Res
, vol.59
, pp. 24-27
-
-
Bullrich, F.1
Rasio, D.2
Kitada, S.3
-
60
-
-
1842328565
-
Llq deletions identify a new subset of B-Cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis
-
Dohner H, Stilgenbauer 5, James MR, et al. llq deletions identify a new subset of B-Cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood 1997;89:2516-2522.
-
(1997)
Blood
, vol.89
, pp. 2516-2522
-
-
Dohner, H.1
Stilgenbauer, S.2
James, M.R.3
-
61
-
-
77957664665
-
Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: A randomised open-label phase 3 trial
-
Hallek M, Fischer K, Fingerle-Rowson G, et al. Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: A randomised, open-label, phase 3 trial. Lancet 2010;376:1 164-1174.
-
(2010)
Lancet
, vol.376
, pp. 1164-1174
-
-
Hallek, M.1
Fischer, K.2
Fingerle-Rowson, G.3
-
62
-
-
78650315158
-
Integrative genomics analyses reveal molecularly distinct subgroups of B-Cell chronic lymphocytic leukemia patients with 13q14 deletion
-
Mosca L, Fabris 5, Lionetti M, et al. Integrative genomics analyses reveal molecularly distinct subgroups of B-Cell chronic lymphocytic leukemia patients with 13q14 deletion. Clin Cancer Res 20 10; 16:5641-5653
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5641-5653
-
-
Mosca, L.1
Fabris, S.2
Lionetti, M.3
-
63
-
-
38949184406
-
Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14
-
Ouillette P, Erba H, Kujawski L, et al. Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14. Cancer Res 2008;68:1012-1021.
-
(2008)
Cancer Res
, vol.68
, pp. 1012-1021
-
-
Ouillette, P.1
Erba, H.2
Kujawski, L.3
-
64
-
-
9844266791
-
Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia
-
Liu Y, Corcoran M, Rasool 0, et al. Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia. Oncogene 1997; 15:2463-2473
-
(1997)
Oncogene
, vol.15
, pp. 2463-2473
-
-
Liu, Y.1
Corcoran, M.2
Rasool, O.3
-
65
-
-
0026514343
-
Retinoblastoma gene deletions in B-Cell chronic lymphocytic leukemia
-
LiuY, Grander D, Soderhall 5, et al. Retinoblastoma gene deletions in B-Cell chronic lymphocytic leukemia. Genes Chromosomes Cancer 1992;4:250-256.
-
(1992)
Genes Chromosomes Cancer
, vol.4
, pp. 250-256
-
-
Liu, Y.1
Grander, D.2
Soderhall, S.3
-
66
-
-
0027227650
-
Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: Evidence for a role of an adjacent locus
-
Liu Y, Szekely L, Grander D, et al. Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: Evidence for a role of an adjacent locus. Proc Natl Acad Scm USA 1993;90:8697-8701.
-
(1993)
Proc Natl Acad Scm USA
, vol.90
, pp. 8697-8701
-
-
Liu, Y.1
Szekely, L.2
Grander, D.3
-
67
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miRl5 and miRl6 at 13q14 in chronic lymphocytic leukemia
-
Calm GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miRl5 and miRl6 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Scm USA 2002;99:15524-15529.
-
(2002)
Proc Natl Acad Scm USA
, vol.99
, pp. 15524-15529
-
-
Calm, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
68
-
-
25444520537
-
MiR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calm GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Scm USA 2005;102: 13944-13949.
-
(2005)
Proc Natl Acad Scm USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calm, G.A.2
Fabbri, M.3
-
69
-
-
84858149539
-
Del(13q14.3) length matters: An integrated analysis of genomic fluorescence in situ hybridization and clinical data in 169 chronic lymphocytic leukaemia patients with 13q deletion alone or a normal karyotype
-
Mian M, Rinaldi A, Mensah AA, et al. Del(13q14.3) length matters: An integrated analysis of genomic, fluorescence in situ hybridization and clinical data in 169 chronic lymphocytic leukaemia patients with 13q deletion alone or a normal karyotype. Hematol Oncol 2012;30:46-49.
-
(2012)
Hematol Oncol
, vol.30
, pp. 46-49
-
-
Mian, M.1
Rinaldi, A.2
Mensah, A.A.3
-
70
-
-
79952453663
-
13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia
-
Parker H, Rose-Zerilli MJ, Parker A, et al. 13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia. Leukemia 2011;25:489-497.
-
(2011)
Leukemia
, vol.25
, pp. 489-497
-
-
Parker, H.1
Rose-Zerilli, M.J.2
Parker, A.3
-
71
-
-
75149160442
-
A comprehensive evaluation of the prognostic significance of 13q deletions in patients with B-chronic lymphocytic leukaemia
-
Prognostic markers in CLL 2363
-
Van Dyke DL, Shanafelt TD, Call TG, et al. A comprehensive evaluation of the prognostic significance of 13q deletions in patients with B-chronic lymphocytic leukaemia. Br J Haematol 2010;148:544-550. Prognostic markers in CLL 2363
-
(2010)
Br J Haematol
, vol.148
, pp. 544-550
-
-
Van Dyke, D.L.1
Shanafelt, T.D.2
Call, T.G.3
-
72
-
-
84860329005
-
Dysfunction of the TPS3 tumor suppressor gene in lymphoid malignancies
-
Xu-Monette ZY, Medeiros U, Li Y, et al. Dysfunction of the TPS3 tumor suppressor gene in lymphoid malignancies. Blood 2012;1 19:3668-3683.
-
(2012)
Blood
, vol.119
, pp. 3668-3683
-
-
Xu-Monette, Z.Y.1
Medeiros, U.2
Li, Y.3
-
73
-
-
58249117812
-
The detection of TPS3 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype
-
Dicker F, Herholz H, Schnittger S, et al. The detection of TPS3 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype. Leukemia 2009;23:1 17-124.
-
(2009)
Leukemia
, vol.23
, pp. 117-124
-
-
Dicker, F.1
Herholz, H.2
Schnittger, S.3
-
74
-
-
54849430966
-
Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with l7p deletion
-
Forconi F, Rinaldi A, Kwee I, et al. Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with l7p deletion. Br J Haematol 2008; 143:532-536.
-
(2008)
Br J Haematol
, vol.143
, pp. 532-536
-
-
Forconi, F.1
Rinaldi, A.2
Kwee, I.3
-
75
-
-
73949135028
-
Monoallelic and biallelic inactivation of TPS3 gene in chronic lymphocytic leukemia: Selection, impact on survival, and response to DNA damage
-
Malcikova J, Smardova J, Rocnova L, et al. Monoallelic and biallelic inactivation of TPS3 gene in chronic lymphocytic leukemia: Selection, impact on survival, and response to DNA damage. Blood 2009;1 14:5307-53 14.
-
(2009)
Blood
, vol.114
, pp. 5307-5314
-
-
Malcikova, J.1
Smardova, J.2
Rocnova, L.3
-
76
-
-
78751702338
-
TP53 mutations are infrequent in newly diagnosed chronic lymphocytic leukemia
-
Zainuddin N, Murray F, Kanduri M, et al. TP53 mutations are infrequent in newly diagnosed chronic lymphocytic leukemia. Leuk Res 2011;35:272-274.
-
(2011)
Leuk Res
, vol.35
, pp. 272-274
-
-
Zainuddin, N.1
Murray, F.2
Kanduri, M.3
-
77
-
-
54049141334
-
Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: Results from a detailed genetic characterization with long-term follow-up
-
Zenz T, Krober A, Scherer K, et al. Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: Results from a detailed genetic characterization with long-term follow-up. Blood 2008;112:3322-3329.
-
(2008)
Blood
, vol.112
, pp. 3322-3329
-
-
Zenz, T.1
Krober, A.2
Scherer, K.3
-
78
-
-
79551504914
-
TP53 mutation and survival in chronic lymphocytic leukemia
-
Zenz I, Eichhorst B, Busch R, et al. TP53 mutation and survival in chronic lymphocytic leukemia. J Clin Oncol 2010;28:4473-4479.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4473-4479
-
-
Zenz, I.1
Eichhorst, B.2
Busch, R.3
-
79
-
-
70350511471
-
Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): Dissecting the contribution of l7p deletion, TP53 mutation, pS3-p2l dysfunction, and miR34a in a prospective clinical trial
-
Zenz T, Habe 5, Denzel I, et al. Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): Dissecting the contribution of l7p deletion, TP53 mutation, pS3-p2l dysfunction, and miR34a in a prospective clinical trial. Blood 2009; 114:2589-2597.
-
(2009)
Blood
, vol.114
, pp. 2589-2597
-
-
Zenz, T.1
Habe, S.2
Denzel, I.3
-
80
-
-
78650307334
-
TP53 mutation profile in chronic lymphocytic leukemia: Evidence for a disease specific profile from a comprehensive analysis of 268 mutations
-
Zenz T, Vollmer D, Trbusek M, et al. TP53 mutation profile in chronic lymphocytic leukemia: Evidence for a disease specific profile from a comprehensive analysis of 268 mutations. Leukemia 2010;24:2072-2079.
-
(2010)
Leukemia
, vol.24
, pp. 2072-2079
-
-
Zenz, T.1
Vollmer, D.2
Trbusek, M.3
-
81
-
-
11144357657
-
Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
-
Lozanski G, Heerema NA, Flinn JW, et al. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood 2004; 103:3278-3281.
-
(2004)
Blood
, vol.103
, pp. 3278-3281
-
-
Lozanski, G.1
Heerema, N.A.2
Flinn, J.W.3
-
82
-
-
69849107362
-
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: Clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group
-
Stilgenbauer 5, Zenz T, Winkler D, et al. Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: Clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2009;27:3994-4001.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3994-4001
-
-
Stilgenbauer, S.1
Zenz, T.2
Winkler, D.3
-
83
-
-
34447530283
-
Assessment offludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): A randomised controlled trial
-
CatovskyD, Richards S, Matutes E, et al. Assessment offludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): A randomised controlled trial. Lancet 2007;370:230-239.
-
(2007)
Lancet
, vol.370
, pp. 230-239
-
-
Catovsky, D.1
Richards, S.2
Matutes, E.3
-
84
-
-
33947544426
-
Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US Intergroup Phase 11I Trial E2997
-
Grever MR, Lucas DM, Dewald GW, et al. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US Intergroup Phase 11I Trial E2997. 1 Clin Oncol 2007;25:799-804.
-
(2007)
1 Clin Oncol
, vol.25
, pp. 799-804
-
-
Grever, M.R.1
Lucas, D.M.2
Dewald, G.W.3
-
85
-
-
70449492043
-
Biologic and clinical markers for outcome after fludarabine (F) or F plus cyclophosphamide (FC) -comprehensive analysis of the CLL4 trial of the GCLLSG
-
Abstract 2089
-
Stilgenbauer 5, Eichhorst BF, Busch R, et al. Biologic and clinical markers for outcome after fludarabine (F) or F plus cyclophosphamide (FC) -comprehensive analysis of the CLL4 trial of the GCLLSG. Blood 2008;1 12(Suppl. 1): Abstract 2089.
-
(2008)
Blood
, vol.112
, Issue.SUPPL. 1
-
-
Stilgenbauer, S.1
Eichhorst, B.F.2
Busch, R.3
-
86
-
-
0028987180
-
P53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-Cell leukemias
-
Dohner H, Fischer K, Bentz M, et al. p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-Cell leukemias. Blood 1995;85:1580-1589.
-
(1995)
Blood
, vol.85
, pp. 1580-1589
-
-
Dohner, H.1
Fischer, K.2
Bentz, M.3
-
87
-
-
0026561988
-
Mutations of the p53 gene in B-Cell chronic lymphocytic leukemia: A report on 39 cases with cytogenetic analysis
-
Fenaux P, Preudhomme C, Lai JL, et al. Mutations of the p53 gene in B-Cell chronic lymphocytic leukemia: A report on 39 cases with cytogenetic analysis. Leukemia 1992;6:246-250.
-
(1992)
Leukemia
, vol.6
, pp. 246-250
-
-
Fenaux, P.1
Preudhomme, C.2
Lai, J.L.3
-
88
-
-
33746137366
-
Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects
-
Pettitt AR, Matutes E, Oscier D. Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects. Leukemia 2006;20:1441-1445.
-
(2006)
Leukemia
, vol.20
, pp. 1441-1445
-
-
Pettitt, A.R.1
Matutes, E.2
Oscier, D.3
-
89
-
-
0021961060
-
Prognostic information from cytogenetic analysis in chronic B-lymphocytic leukemia and leukemic immunocytoma
-
Juliusson G, Robert KH, Ost A, et al. Prognostic information from cytogenetic analysis in chronic B-lymphocytic leukemia and leukemic immunocytoma. Blood 1985;65:134-141.
-
(1985)
Blood
, vol.65
, pp. 134-141
-
-
Juliusson, G.1
Robert, K.H.2
Ost, A.3
-
90
-
-
0031889653
-
Cytogenetics in chronic lymphocytic leukemia
-
Juliusson G, Merup M. Cytogenetics in chronic lymphocytic leukemia. Semin Oncol 1998;25:19-26.
-
(1998)
Semin Oncol
, vol.25
, pp. 19-26
-
-
Juliusson, G.1
Merup, M.2
-
91
-
-
10744225365
-
Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations
-
Schwaenen C, Nessling M, Wessendorf 5, et al. Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations. Proc Natl Acad Sci USA 2004;101:1039-1044.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1039-1044
-
-
Schwaenen, C.1
Nessling, M.2
Wessendorf, S.3
-
92
-
-
34250871226
-
Trisomy 19 is associated with trisomy 12 and mutated IGHV genes in B-chronic lymphocytic leukaemia
-
Sellmann L, Gesk 5, Walter C, et al. Trisomy 19 is associated with trisomy 12 and mutated IGHV genes in B-chronic lymphocytic leukaemia. Br J Haematol 2007;138:217-220.
-
(2007)
Br J Haematol
, vol.138
, pp. 217-220
-
-
Sellmann, L.1
Gesk, S.2
Walter, C.3
-
93
-
-
84856761225
-
Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant
-
Ibbotson R, Athanasiadou A, Sutton LA, et al. Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant. Leukemia 2012;26:170-172.
-
(2012)
Leukemia
, vol.26
, pp. 170-172
-
-
Ibbotson, R.1
Athanasiadou, A.2
Sutton, L.A.3
-
94
-
-
40849084172
-
Recurrent cytogenetic findings in subsets of patients with chronic lymphocytic leukemia expressing IgG-switched stereotyped immunoglobulins
-
Athanasiadou A, Stamatopoulos K, Gaitatzi M, et al. Recurrent cytogenetic findings in subsets of patients with chronic lymphocytic leukemia expressing IgG-switched stereotyped immunoglobulins. Haematologica 2008;93:473-474.
-
(2008)
Haematologica
, vol.93
, pp. 473-474
-
-
Athanasiadou, A.1
Stamatopoulos, K.2
Gaitatzi, M.3
-
95
-
-
56249115900
-
The most frequent t(14;19)(q32;q13)-positive B-Cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia
-
Chapiro E, Radford-Weiss I, Bastard C, et al. The most frequent t(14;19)(q32;q13)-positive B-Cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia. Leukemia 2008;22:2123-2127.
-
(2008)
Leukemia
, vol.22
, pp. 2123-2127
-
-
Chapiro, E.1
Radford-Weiss, I.2
Bastard, C.3
-
96
-
-
34250811924
-
A comprehensive genetic and histopathologic analysis identifies two subgroups of B-Cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation
-
Martin-Subero JI, Ibbotson R, Klapper W, et al. A comprehensive genetic and histopathologic analysis identifies two subgroups of B-Cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation. Leukemia 2007;21:1532-1544.
-
(2007)
Leukemia
, vol.21
, pp. 1532-1544
-
-
Martin-Subero, J.I.1
Ibbotson, R.2
Klapper, W.3
-
97
-
-
41349120731
-
Shorttelomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia
-
Roos G, KroberA, Grabowski P, et al. Shorttelomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia. Blood 2008;111:2246-2252.
-
(2008)
Blood
, vol.111
, pp. 2246-2252
-
-
Roos, G.1
Krober, A.2
Grabowski, P.3
-
98
-
-
84870763388
-
High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations
-
Edelmann J, Holzmann K, Miller F, et al. High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations. Blood 2012;120:4783-4794.
-
(2012)
Blood
, vol.120
, pp. 4783-4794
-
-
Edelmann, J.1
Holzmann, K.2
Miller, F.3
-
99
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens PJ, Greenman CD, Fu B, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011;144:27-40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
-
100
-
-
33846048039
-
Targeting the NFkappaB signaling pathway in Notchi-Induced I-Cell leukemia
-
Vilimas T, Mascarenhas J, Palomero T, et al. Targeting the NFkappaB signaling pathway in Notchi-Induced I-Cell leukemia. Nat Med 2007 13:70-77
-
(2007)
Nat Med
, vol.13
, pp. 70-77
-
-
Vilimas, T.1
Mascarenhas, J.2
Palomero, T.3
-
101
-
-
33846048039
-
Targeting the NFkappaB signaling pathway in Notchi-Induced I-Cell leukemia
-
Vilimas T, Mascarenhas J, Palomero T, et al. Targeting the NFkappaB signaling pathway in Notchi-Induced I-Cell leukemia. Nat Med 2007;13:70-77.
-
(2007)
Nat Med
, vol.13
, pp. 70-77
-
-
Vilimas, T.1
Mascarenhas, J.2
Palomero, T.3
-
102
-
-
34848842174
-
Notchi engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells
-
Santos MA, Sarmento LM, Rebelo M, et al. Notchi engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells. Proc Natl Acad Sci USA 2007;104:15454-15459.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15454-15459
-
-
Santos, M.A.1
Sarmento, L.M.2
Rebelo, M.3
-
103
-
-
59649083306
-
Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells
-
Rosati E, Sabatini R, Rampino G, et al. Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells. Blood 2009;113:856-865.
-
(2009)
Blood
, vol.113
, pp. 856-865
-
-
Rosati, E.1
Sabatini, R.2
Rampino, G.3
-
104
-
-
84857739865
-
NOTCH1 mutations in + 12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of+ 12 CLL
-
Del Giudice I, Rossi D, Chiaretti 5, et al. NOTCH1 mutations in + 12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of+ 12 CLL. Haematologica 2012;97:437-441.
-
(2012)
Haematologica
, vol.97
, pp. 437-441
-
-
Del Giudice, I.1
Rossi, D.2
Chiaretti, S.3
-
105
-
-
84855860383
-
NOTCH1 mutations in CLL associated with trisomy 12
-
BalattiV, BottoniA, PalamarchukA, et al. NOTCH1 mutations in CLL associated with trisomy 12. Blood 2012;119:329-331.
-
(2012)
Blood
, vol.119
, pp. 329-331
-
-
Balatti, V.1
Bottoni, A.2
Palamarchuk, A.3
-
106
-
-
84872469222
-
The clinical significance ofNOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
-
Oscier DG, Rose-Zerilli MJ, Winkelmann N, et al. The clinical significance ofNOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial. Blood 2013;121:468-475.
-
(2013)
Blood
, vol.121
, pp. 468-475
-
-
Oscier, D.G.1
Rose-Zerilli, M.J.2
Winkelmann, N.3
-
107
-
-
84855854025
-
Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
-
Rossi D, Rasi 5, Fabbri G, et al. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia. Blood 2012;119:521-529.
-
(2012)
Blood
, vol.119
, pp. 521-529
-
-
Rossi, D.1
Rasi, S.2
Fabbri, G.3
-
108
-
-
84877637121
-
NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome
-
2012 Dec 6
-
Villamor N, Conde U, Martinez-Trillos A, et al. NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome. Leukemia 2012 Dec 6.
-
Leukemia
-
-
Villamor, N.1
Conde, U.2
Martinez-Trillos, A.3
-
109
-
-
84863833162
-
Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome
-
Rossi D, Rasi S, Spina V, et al. Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome. Br 1 Haematol 2012;158:426-429.
-
(2012)
Br 1 Haematol
, vol.158
, pp. 426-429
-
-
Rossi, D.1
Rasi, S.2
Spina, V.3
-
110
-
-
77958567414
-
NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CUU
-
Sportoletti P, Baldoni 5, Cavalli U, et al. NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CUU. Br J Haematol 20 10; 15 1:404-406.
-
(2010)
Br J Haematol
, vol.151
, pp. 404-406
-
-
Sportoletti, P.1
Baldoni, S.2
Cavalli, U.3
-
111
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl MC, Will CU, Uuhrmann R. The spliceosome: Design principles of a dynamic RNP machine. Cell 2009; 136:701-718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.U.2
Uuhrmann, R.3
-
112
-
-
84255160977
-
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness
-
Rossi D, Bruscaggin A, Spina V, et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness. Blood 201 1;118:6904-6908.
-
(2011)
Blood
, vol.118
, pp. 6904-6908
-
-
Rossi, D.1
Bruscaggin, A.2
Spina, V.3
-
113
-
-
80855133512
-
Alteration of BIRC3 and multiple other NF-kappaB pathway genes in splenic marginal zone lymphoma
-
Rossi D, Deaglio 5, Dominguez-Sola D, et al. Alteration of BIRC3 and multiple other NF-kappaB pathway genes in splenic marginal zone lymphoma. Blood 2011;118:4930-4934.
-
(2011)
Blood
, vol.118
, pp. 4930-4934
-
-
Rossi, D.1
Deaglio, S.2
Dominguez-Sola, D.3
-
114
-
-
77957366071
-
Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cellsviaNF-kappaB activation and denovogenetranscription
-
Buggins AG, Pepper C, Patten PE, et al. Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cellsviaNF-kappaB activation and denovogenetranscription. Cancer Res 2010;70:7523-7533.
-
(2010)
Cancer Res
, vol.70
, pp. 7523-7533
-
-
Buggins, A.G.1
Pepper, C.2
Patten, P.E.3
-
115
-
-
78751549662
-
The lymph node microenvironment promotes B-Cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia
-
Herishanu Y, Perez-Galan P, Uiu D, et al. The lymph node microenvironment promotes B-Cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia. Blood 2011;117:563-574.
-
(2011)
Blood
, vol.117
, pp. 563-574
-
-
Herishanu, Y.1
Perez-Galan, P.2
Uiu, D.3
-
116
-
-
50349083286
-
Evolution and function of the ADP ribosyl cyclase/CD38 gene familyin physiology and pathology
-
Malavasi F, Deaglio 5, Funaro A, et al. Evolution and function of the ADP ribosyl cyclase/CD38 gene familyin physiology and pathology. Physiol Rev 2008;88:841-886.
-
(2008)
Physiol Rev
, vol.88
, pp. 841-886
-
-
Malavasi, F.1
Deaglio, S.2
Funaro, A.3
-
117
-
-
0036464608
-
CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease
-
Hamblin TJ, Orchard JA, Ibbotson RE, et al. CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood 2002;99:1023-1029.
-
(2002)
Blood
, vol.99
, pp. 1023-1029
-
-
Hamblin, T.J.1
Orchard, J.A.2
Ibbotson, R.E.3
-
118
-
-
0035869282
-
CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia
-
Thunberg U, Johnson A, Roos G, et al. CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia. Blood 2001;97:1892-1894.
-
(2001)
Blood
, vol.97
, pp. 1892-1894
-
-
Thunberg, U.1
Johnson, A.2
Roos, G.3
-
119
-
-
0037441762
-
The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukemia (CLL) patients at risk of disease progression
-
Ghia P, Guida G, Stella 5, et al. The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukemia (CLL) patients at risk of disease progression. Blood 2003; 101:1262-1269.
-
(2003)
Blood
, vol.101
, pp. 1262-1269
-
-
Ghia, P.1
Guida, G.2
Stella, S.3
-
120
-
-
79251581902
-
Towards effective immunotherapy of myeloma: Enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab
-
Van derVeerMS, de Weers M, Van Kessel B, et al. Towards effective immunotherapy of myeloma: Enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab. Raematologica 2011;96:284-290.
-
(2011)
Raematologica
, vol.96
, pp. 284-290
-
-
Van Der Veer, M.S.1
De Weers, M.2
Van Kessel, B.3
-
121
-
-
0026483786
-
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the ICR zeta chain
-
Chan AC, Iwashima M, Iurck CW, et al. ZAP-70: A 70 kd protein-tyrosine kinase that associates with the ICR zeta chain. Cell 1992;1:649-662
-
(1992)
Cell
, vol.1
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Iurck, C.W.3
-
122
-
-
0029133646
-
Essential role for ZAP-70 in both positive and negative selection of thymocytes
-
Negishi I, Motoyama N, Nakayama K, et al. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 1995;376:435-438.
-
(1995)
Nature
, vol.376
, pp. 435-438
-
-
Negishi, I.1
Motoyama, N.2
Nakayama, K.3
-
123
-
-
33646472451
-
ZAP-70 is expressed by normal and malignant human B-Cell subsets of different maturational stage
-
Scielzo C, Camporeale A, Geuna M, et al. ZAP-70 is expressed by normal and malignant human B-Cell subsets of different maturational stage. Leukemia 2006;20:689-695.
-
(2006)
Leukemia
, vol.20
, pp. 689-695
-
-
Scielzo, C.1
Camporeale, A.2
Geuna, M.3
-
124
-
-
0037114744
-
Expression of ZAP-70 is associated with increased B-Cell receptor signaling in chronic lymphocytic leukemia
-
Chen L, Widhopf G, Ruynh L, et al. Expression of ZAP-70 is associated with increased B-Cell receptor signaling in chronic lymphocytic leukemia. Blood 2002;100:4609-4614.
-
(2002)
Blood
, vol.100
, pp. 4609-4614
-
-
Chen, L.1
Widhopf, G.2
Ruynh, L.3
-
125
-
-
36148978171
-
Signaling pathways activated by antigen-receptor engagement in chronic lymphocytic leukemia B-cells
-
Efremov DG, Gobessi 5, Longo PG. Signaling pathways activated by antigen-receptor engagement in chronic lymphocytic leukemia B-cells. Autoimmun Rev 2007;7:102-108.
-
(2007)
Autoimmun Rev
, vol.7
, pp. 102-108
-
-
Efremov, D.G.1
Gobessi, S.2
Longo, P.G.3
-
126
-
-
0035803371
-
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
-
Rosenwald A, Alizadeh AA, Widhopf G, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001;194:1639-1647.
-
(2001)
J Exp Med
, vol.194
, pp. 1639-1647
-
-
Rosenwald, A.1
Alizadeh, A.A.2
Widhopf, G.3
-
127
-
-
0037406968
-
ZAP-70 expression as a surrogate for immunoglobulin-variable -region mutations in chronic lymphocytic leukemia
-
Crespo M, Bosch F, Villamor N, et al. ZAP-70 expression as a surrogate for immunoglobulin-variable -region mutations in chronic lymphocytic leukemia. N Engl J Med 2003;348:1764-1775.
-
(2003)
N Engl J Med
, vol.348
, pp. 1764-1775
-
-
Crespo, M.1
Bosch, F.2
Villamor, N.3
-
128
-
-
0347318114
-
ZAP-70 expression and prognosis in chronic lymphocytic leukaemia
-
Orchard JA, Ibbotson RE, Davis Z, et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004;363:105-111.
-
(2004)
Lancet
, vol.363
, pp. 105-111
-
-
Orchard, J.A.1
Ibbotson, R.E.2
Davis, Z.3
-
129
-
-
10744222814
-
ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
-
Wiestner A, Rosenwald A, Barry IS, et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 2003;101:4944-4951.
-
(2003)
Blood
, vol.101
, pp. 4944-4951
-
-
Wiestner, A.1
Rosenwald, A.2
Barry, I.S.3
-
130
-
-
33644881106
-
Additional genetic high-risk features such as llq deletion l7p deletion and V3-21 usage characterize discordance of ZAP-70 and yR mutation status in chronic lymphocytic leukemia
-
Krober A, Bloehdorn J, Rather 5, et al. Additional genetic high-risk features such as llq deletion, l7p deletion, and V3-21 usage characterize discordance of ZAP-70 and yR mutation status in chronic lymphocytic leukemia. J Clin Oncol 2006;24:969-975.
-
(2006)
J Clin Oncol
, vol.24
, pp. 969-975
-
-
Krober, A.1
Bloehdorn, J.2
Rather, S.3
-
132
-
-
0033031853
-
Differentiation of human monocytes to monocyte-derived macrophages is associated with increased lipoprotein lipase-Induced tumor necrosis factor-alpha expression and production: A process involving cell surface proteoglycans and protein kinase C
-
Mamputu JC, Renier G. Differentiation of human monocytes to monocyte-derived macrophages is associated with increased lipoprotein lipase-Induced tumor necrosis factor-alpha expression and production: A process involving cell surface proteoglycans and protein kinase C. Arterioscler Thromb Vasc Biol 1999;19:1405-1411.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 1405-1411
-
-
Mamputu, J.C.1
Renier, G.2
-
133
-
-
77649186881
-
Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity
-
Mansouri M, Sevov M, Fahlgren E, et al. Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity. Leuk Res 2010;34:301-306.
-
(2010)
Leuk Res
, vol.34
, pp. 301-306
-
-
Mansouri, M.1
Sevov, M.2
Fahlgren, E.3
-
134
-
-
0035803464
-
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
-
Klein U, Th Y, Stolovitzky GA, et al. Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med 2001;194:1625-1638.
-
(2001)
J Exp Med
, vol.194
, pp. 1625-1638
-
-
Klein, U.1
Th, Y.2
Stolovitzky, G.A.3
-
135
-
-
21744437314
-
Righ expression of lipoprotein lipase in poor risk B-Cell chronic lymphocytic leukemia
-
Reintel D, Kienle D, Shehata M, et al. Righ expression of lipoprotein lipase in poor risk B-Cell chronic lymphocytic leukemia. Leukemia 2005;19:1216-1223.
-
(2005)
Leukemia
, vol.19
, pp. 1216-1223
-
-
Reintel, D.1
Kienle, D.2
Shehata, M.3
-
136
-
-
79961085844
-
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia
-
Kaderi MA, Kanduri M, Buhl AM, et al. LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia. Raematologica 2011;96: 1153-1160.
-
(2011)
Raematologica
, vol.96
, pp. 1153-1160
-
-
Kaderi, M.A.1
Kanduri, M.2
Buhl, A.M.3
-
137
-
-
73949119178
-
Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia
-
Kienle D, Benner A, Laufle C, et al. Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia. Raematologica 2010;95:102-109.
-
(2010)
Raematologica
, vol.95
, pp. 102-109
-
-
Kienle, D.1
Benner, A.2
Laufle, C.3
-
138
-
-
22144480303
-
The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia
-
Oppezzo P, Vasconcelosy, Settegrana C, et al. The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia. Blood 2005;106:650-657.
-
(2005)
Blood
, vol.106
, pp. 650-657
-
-
Oppezzo, P.1
Vasconcelosy Settegrana, C.2
-
139
-
-
33847378042
-
Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia
-
Van Bockstaele F, Pede V, Janssens A, et al. Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia. Clin Chem 2007;53:204-212.
-
(2007)
Clin Chem
, vol.53
, pp. 204-212
-
-
Van Bockstaele, F.1
Pede, V.2
Janssens, A.3
-
140
-
-
32544451164
-
The predictive value oflipoprotein lipase for survival in chronic lymphocytic leukemia
-
van?tVeerMB, BrooijmansAM, LangerakAW, et al. The predictive value oflipoprotein lipase for survival in chronic lymphocytic leukemia. Raematologica 2006;91:56-63.
-
(2006)
Raematologica
, vol.91
, pp. 56-63
-
-
Vant Veer, M.B.1
Brooijmans, A.M.2
Langerak, A.W.3
-
141
-
-
84856248636
-
RNA-based markers as prognostic factors in chronic lymphocytic leukemia
-
Sevov M, Rosenquist R, Mansouri L. RNA-based markers as prognostic factors in chronic lymphocytic leukemia. Expert Rev Rematol 2012;5:69-79.
-
(2012)
Expert Rev Rematol
, vol.5
, pp. 69-79
-
-
Sevov, M.1
Rosenquist, R.2
Mansouri, L.3
-
142
-
-
33645519229
-
Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia
-
Buhl AM, Jurlander L Jorgensen PS, et al. Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia. Blood 2006;107:2904-2911.
-
(2006)
Blood
, vol.107
, pp. 2904-2911
-
-
Buhl, A.M.1
Jurlander, L.2
Jorgensen, P.S.3
-
143
-
-
33645513159
-
CLLU1 expression levels predict time to initiation of therapy and overall survival in chronic lymphocytic leukemia
-
Buhl AM, Jurlander J, Geisler CH, et al. CLLU1 expression levels predict time to initiation of therapy and overall survival in chronic lymphocytic leukemia. Eur J Raematol 2006;76:455-464.
-
(2006)
Eur J Raematol
, vol.76
, pp. 455-464
-
-
Buhl, A.M.1
Jurlander, J.2
Geisler, C.H.3
-
144
-
-
34249651313
-
CLLU1 expression analysis adds prognostic information to risk prediction in chronic lymphocytic leukemia
-
Josefsson P, Geisler CH, Leffers R, et al. CLLU1 expression analysis adds prognostic information to risk prediction in chronic lymphocytic leukemia. Blood 2007;109:4973-4979.
-
(2007)
Blood
, vol.109
, pp. 4973-4979
-
-
Josefsson, P.1
Geisler, C.H.2
Leffers, R.3
-
145
-
-
77958541352
-
A molecular score by quantitative PCR as a new prognostic tool at diagnosis for chronic lymphocytic leukemia patients
-
Stamatopoulos B, Meuleman N, De Bruyn C, et al. A molecular score by quantitative PCR as a new prognostic tool at diagnosis for chronic lymphocytic leukemia patients. PLoS One 2010;5. pu: E12780.
-
(2010)
PLoS One
, vol.5
-
-
Stamatopoulos, B.1
Meuleman, N.2
De Bruyn, C.3
-
146
-
-
84875320653
-
CLLU1 expression has prognostic value in CLL after first-line therapy in younger patients and those with mutated IGHV genes
-
Gonzalez D, Else M, Wren D, et al. CLLU1 expression has prognostic value in CLL after first-line therapy in younger patients and those with mutated IGHV genes. Raematologica 2013;98:274-278.
-
(2013)
Raematologica
, vol.98
, pp. 274-278
-
-
Gonzalez, D.1
Else, M.2
Wren, D.3
-
147
-
-
79954420745
-
Analysis of CLLU1 expression levels before and after therapy in patients with chronic lymphocytic leukemia
-
Buhl AM, James DF, Neuberg D, et al. Analysis of CLLU1 expression levels before and after therapy in patients with chronic lymphocytic leukemia. Eur J Raematol 2011;86:405-411.
-
(2011)
Eur J Raematol
, vol.86
, pp. 405-411
-
-
Buhl, A.M.1
James, D.F.2
Neuberg, D.3
-
148
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calm GA, Ferracin M, Cimmino A, et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 2005;353:1793-1801.
-
(2005)
N Engl J Med
, vol.353
, pp. 1793-1801
-
-
Calm, G.A.1
Ferracin, M.2
Cimmino, A.3
-
149
-
-
34249661649
-
Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia
-
Fulci V, Chiaretti 5, Goldoni M, et al. Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood 2007;109:4944-4951.
-
(2007)
Blood
, vol.109
, pp. 4944-4951
-
-
Fulci, V.1
Chiaretti, S.2
Goldoni, M.3
-
150
-
-
39149134593
-
Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis
-
Marton 5, Garcia MR, Robello C, et al. Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis. Leukemia 2008;22:330-338.
-
(2008)
Leukemia
, vol.22
, pp. 330-338
-
-
Marton, S.1
Garcia, M.R.2
Robello, C.3
-
151
-
-
33846190181
-
Icli expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
-
Pekarsky Y, Santanam U, Cimmino A, et al. Icli expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006;66:11590-11593.
-
(2006)
Cancer Res
, vol.66
, pp. 11590-11593
-
-
Pekarsky, Y.1
Santanam, U.2
Cimmino, A.3
-
152
-
-
77956556260
-
MicroRNA fingerprinting of CLL patients with chromosome l7p deletion identify a miR-21 score that stratifies early survival
-
Rossi 5, Shimizu M, Barbarotto E, et al. microRNA fingerprinting of CLL patients with chromosome l7p deletion identify a miR-21 score that stratifies early survival. Blood 2010;116:945-952.
-
(2010)
Blood
, vol.116
, pp. 945-952
-
-
Rossi, S.1
Shimizu, M.2
Barbarotto, E.3
-
153
-
-
67149147424
-
MicroRNA29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification
-
Stamatopoulos B, Meuleman N, Raibe-Kains B, et al. microRNA29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification. Blood 2009;113:5237-5245.
-
(2009)
Blood
, vol.113
, pp. 5237-5245
-
-
Stamatopoulos, B.1
Meuleman, N.2
Raibe-Kains, B.3
-
154
-
-
65549110908
-
MiR-34a as part of the resistance network in chronic lymphocytic leukemia
-
Zenz T, Mohr J, Eldering E, et al. miR-34a as part of the resistance network in chronic lymphocytic leukemia. Blood 2009;113:3801-3808.
-
(2009)
Blood
, vol.113
, pp. 3801-3808
-
-
Zenz, T.1
Mohr, J.2
Eldering, E.3
-
155
-
-
84861407849
-
MicroRNA-223 expression is uniformly down-regulated in B cell lymphoproliferative disorders and is associated with poor survival in patients with chronic lymphocytic leukemia
-
Zhou K, Yi 5, Yu Z, et al. MicroRNA-223 expression is uniformly down-regulated in B cell lymphoproliferative disorders and is associated with poor survival in patients with chronic lymphocytic leukemia. Leuk Lymphoma 2012;53:1 155-1161.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 1155-1161
-
-
Zhou, K.1
Yi, S.2
Yu, Z.3
-
156
-
-
33947104955
-
Dynamic regulation of miRNA expression in ordered stages of cellular development
-
Neilson JR, Zheng GX, Burge CB, et al. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev 2007;21:578-589.
-
(2007)
Genes Dev
, vol.21
, pp. 578-589
-
-
Neilson, J.R.1
Zheng, G.X.2
Burge, C.B.3
-
157
-
-
77955485242
-
Toward a comprehensive prognostic scoring system in chronic lymphocytic leukemia based on a combination of genetic parameters
-
Raferlach C, Dicker F, Weiss T, et al. Toward a comprehensive prognostic scoring system in chronic lymphocytic leukemia based on a combination of genetic parameters. Genes Chromosomes Cancer 2010;49:851-859.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 851-859
-
-
Raferlach, C.1
Dicker, F.2
Weiss, T.3
-
158
-
-
80755127112
-
Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia
-
Wierda WG, O?Brien 5, Wang X, et al. Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia. J Clin Oncol 2011;29:4088-4095.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4088-4095
-
-
Wierda, W.G.1
Obrien, S.2
Wang, X.3
-
159
-
-
84856260422
-
Defining the prognosis of early stage chronic lymphocytic leukaemia patients
-
Pepper C, Majid A, Lin TT, et al. Defining the prognosis of early stage chronic lymphocytic leukaemia patients. Br J Raematol 20 12; 156:499-507
-
(2012)
Br J Raematol
, vol.156
, pp. 499-507
-
-
Pepper, C.1
Majid, A.2
Lin, T.T.3
-
162
-
-
33750577939
-
Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia
-
Shanafelt TD, Witzig TE, Fink SR, et al. Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia. J Clin Oncol 2006;24:4634-4641.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4634-4641
-
-
Shanafelt, T.D.1
Witzig, T.E.2
Fink, S.R.3
-
163
-
-
36349025291
-
Clonal evolution in chronic lymphocytic leukemia: Acquisition of high-risk genomic aberrations associated with unmutated VR, resistance to therapy, and short survival
-
Stilgenbauer 5, Sander 5, Bullinger L, et al. Clonal evolution in chronic lymphocytic leukemia: Acquisition of high-risk genomic aberrations associated with unmutated VR, resistance to therapy, and short survival. Raematologica 2007;92:1242-1245.
-
(2007)
Raematologica
, vol.92
, pp. 1242-1245
-
-
Stilgenbauer, S.1
Sander, S.2
Bullinger, L.3
-
164
-
-
84887317173
-
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: The case of SF3B1 and subset #2
-
doi:10.1038/leu.2013.98
-
Strefford J, Sutton LA, Baliakas P, Agathangelidis A, Maléfková J, Plevova K, Scarfó L, Davis Z, Stalika E, Cortese D, Cahill N, Bredo Pedersen L, Francia di Celle P, Tzenou T, Geisler C, Panagiotidis P, Langerak AW, Chiorazzi N, Pospisilova 5, Oscier D, Davi F, Belessi C, Mansouri L, Ghia P, Stamatopoulos K, Rosenquist R. Distinct patterns
-
(2013)
Leukemia.
-
-
Strefford, J.1
Sutton, L.A.2
Baliakas, P.3
Agathangelidis, A.4
Maléfková, J.5
Plevova, K.6
Scarfó, L.7
Davis, Z.8
Stalika, E.9
Cortese, D.10
Cahill, N.11
Bredo Pedersen, L.12
Francia Di Celle, P.13
Tzenou, T.14
Geisler, C.15
Panagiotidis, P.16
Langerak, A.W.17
Chiorazzi, N.18
Pospisilova, S.19
Oscier, D.20
Davi, F.21
Belessi, C.22
Mansouri, L.23
Ghia, P.24
Stamatopoulos, K.25
Rosenquist, R.26
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