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Volumn 121, Issue 8, 2013, Pages 1403-1412

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

(24)  Rossi, Davide a   Rasi, Silvia a   Spina, Valeria a   Bruscaggin, Alessio a   Monti, Sara a   Ciardullo, Carmela a   Deambrogi, Clara a   Khiabanian, Hossein b   Serra, Roberto a   Bertoni, Francesco c   Forconi, Francesco d,e   Laurenti, Luca f   Marasca, Roberto g   Dal Bo, Michele h   Rossi, Francesca Maria h   Bulian, Pietro h   Nomdedeu, Josep i   Del Poeta, Giovanni j   Gattei, Valter h   Pasqualucci, Laura b,k,l   more..


Author keywords

[No Author keywords available]

Indexed keywords

BIRC3 PROTEIN; CYCLOPHOSPHAMIDE; FLUDARABINE; NOTCH1 RECEPTOR; PENTOSTATIN; PROTEIN; PROTEIN P53; RITUXIMAB; SF3B1 PROTEIN; UNCLASSIFIED DRUG;

EID: 84874428346     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-09-458265     Document Type: Article
Times cited : (405)

References (39)
  • 1
    • 40749132494 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia
    • DOI 10.1016/S0140-6736(08)60456-0, PII S0140673608604560
    • Dighiero G, Hamblin TJ. Chronic lymphocytic leukaemia. Lancet. 2008;371(9617):1017-1029. (Pubitemid 351389535)
    • (2008) The Lancet , vol.371 , Issue.9617 , pp. 1017-1029
    • Dighiero, G.1    Hamblin, T.2
  • 2
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood. 2008;111(12):5446-5456.
    • (2008) Blood. , vol.111 , Issue.12 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 4
    • 84863778287 scopus 로고    scopus 로고
    • ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia
    • Pospisilova S, Gonzalez D, Malcikova J, et al. ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia. Leukemia. 2012;26(7):1458-1461.
    • (2012) Leukemia. , vol.26 , Issue.7 , pp. 1458-1461
    • Pospisilova, S.1    Gonzalez, D.2    Malcikova, J.3
  • 5
    • 79960353160 scopus 로고    scopus 로고
    • Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
    • Fabbri G, Rasi S, Rossi D, et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med. 2011;208(7):1389-1401.
    • (2011) J Exp Med. , vol.208 , Issue.7 , pp. 1389-1401
    • Fabbri, G.1    Rasi, S.2    Rossi, D.3
  • 6
    • 79960036578 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
    • Puente XS, Pinyol M, Quesada V, et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature. 2011;475(7354):101-105.
    • (2011) Nature , vol.475 , Issue.7354 , pp. 101-105
    • Puente, X.S.1    Pinyol, M.2    Quesada, V.3
  • 7
    • 84555171449 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
    • Quesada V, Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet. 2012;44(1):47-52.
    • (2012) Nat Genet. , vol.44 , Issue.1 , pp. 47-52
    • Quesada, V.1    Conde, L.2    Villamor, N.3
  • 8
    • 84255160977 scopus 로고    scopus 로고
    • Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness
    • Rossi D, Bruscaggin A, Spina V, et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness. Blood. 2011;118(26):6904-6908.
    • (2011) Blood. , vol.118 , Issue.26 , pp. 6904-6908
    • Rossi, D.1    Bruscaggin, A.2    Spina, V.3
  • 9
    • 84855370035 scopus 로고    scopus 로고
    • SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
    • Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med. 2011;365(26):2497-2506.
    • (2011) N Engl J Med. , vol.365 , Issue.26 , pp. 2497-2506
    • Wang, L.1    Lawrence, M.S.2    Wan, Y.3
  • 10
    • 84855854025 scopus 로고    scopus 로고
    • Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
    • Rossi D, Rasi S, Fabbri G, et al. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia. Blood. 2012;119(2):521-529.
    • (2012) Blood. , vol.119 , Issue.2 , pp. 521-529
    • Rossi, D.1    Rasi, S.2    Fabbri, G.3
  • 11
    • 84858859064 scopus 로고    scopus 로고
    • Disruption of BIRC3 associates with fludarabine chemorefrac-toriness in TP53 wild-type chronic lymphocytic leukemia
    • Rossi D, Fangazio M, Rasi S, et al. Disruption of BIRC3 associates with fludarabine chemorefrac-toriness in TP53 wild-type chronic lymphocytic leukemia. Blood. 2012;119(12):2854-2862.
    • (2012) Blood. , vol.119 , Issue.12 , pp. 2854-2862
    • Rossi, D.1    Fangazio, M.2    Rasi, S.3
  • 13
    • 54049141334 scopus 로고    scopus 로고
    • Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: Results from a detailed genetic characterization with long-term follow-up
    • Zenz T, Kröber A, Scherer K, et al. Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up. Blood. 2008;112(8):3322-3329.
    • (2008) Blood. , vol.112 , Issue.8 , pp. 3322-3329
    • Zenz, T.1    Kröber, A.2    Scherer, K.3
  • 14
    • 79953117852 scopus 로고    scopus 로고
    • The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation
    • Rossi D, Spina V, Deambrogi C, et al. The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation. Blood. 2011;117(12):3391-3401.
    • (2011) Blood. , vol.117 , Issue.12 , pp. 3391-3401
    • Rossi, D.1    Spina, V.2    Deambrogi, C.3
  • 15
    • 52649091186 scopus 로고    scopus 로고
    • Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia
    • Kujawski L, Ouillette P, Erba H, et al. Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. Blood. 2008;112(5):1993-2003.
    • (2008) Blood. , vol.112 , Issue.5 , pp. 1993-2003
    • Kujawski, L.1    Ouillette, P.2    Erba, H.3
  • 16
    • 74249084263 scopus 로고    scopus 로고
    • Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: A high-resolution genomic screening of newly diagnosed patients
    • Gunnarsson R, Isaksson A, Mansouri M, et al. Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients. Leukemia. 2010;24(1):211-215.
    • (2010) Leukemia. , vol.24 , Issue.1 , pp. 211-215
    • Gunnarsson, R.1    Isaksson, A.2    Mansouri, M.3
  • 17
    • 76049087341 scopus 로고    scopus 로고
    • Aggressive chronic lymphocytic leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks
    • Ouillette P, Fossum S, Parkin B, et al. Aggressive chronic lymphocytic leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks. Clin Cancer Res. 2010;16(3):835-847.
    • (2010) Clin Cancer Res. , vol.16 , Issue.3 , pp. 835-847
    • Ouillette, P.1    Fossum, S.2    Parkin, B.3
  • 18
    • 79961059215 scopus 로고    scopus 로고
    • Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
    • Gunnarsson R, Mansouri L, Isaksson A, et al. Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia. Haematologica. 2011;96(8):1161-1169.
    • (2011) Haematologica. , vol.96 , Issue.8 , pp. 1161-1169
    • Gunnarsson, R.1    Mansouri, L.2    Isaksson, A.3
  • 19
    • 80052936981 scopus 로고    scopus 로고
    • Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia
    • Ouillette P, Collins R, Shakhan S, et al. Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia. Blood. 2011;118(11):3051-3061.
    • (2011) Blood. , vol.118 , Issue.11 , pp. 3051-3061
    • Ouillette, P.1    Collins, R.2    Shakhan, S.3
  • 20
    • 84863785266 scopus 로고    scopus 로고
    • Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lympho-cytic leukemia
    • Knight SJ, Yau C, Clifford R, et al. Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lympho-cytic leukemia. Leukemia. 2012;26(7):1564-1575.
    • (2012) Leukemia. , vol.26 , Issue.7 , pp. 1564-1575
    • Knight, S.J.1    Yau, C.2    Clifford, R.3
  • 21
    • 84860705573 scopus 로고    scopus 로고
    • Characteristics of chronic lymphocytic leukemia with so-matically acquired mutations in NOTCH1 exon 34
    • Shedden K, Li Y, Ouillette P, Malek SN. Characteristics of chronic lymphocytic leukemia with so-matically acquired mutations in NOTCH1 exon 34. Leukemia. 2012;26(5):1108-1110.
    • (2012) Leukemia. , vol.26 , Issue.5 , pp. 1108-1110
    • Shedden, K.1    Li, Y.2    Ouillette, P.3    Malek, S.N.4
  • 22
    • 84869753284 scopus 로고    scopus 로고
    • Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns
    • Schuh A, Becq J, Humphray S, et al. Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns. Blood. 2012;120(20):4191-4196.
    • (2012) Blood. , vol.120 , Issue.20 , pp. 4191-4196
    • Schuh, A.1    Becq, J.2    Humphray, S.3
  • 23
    • 0031536511 scopus 로고    scopus 로고
    • Improvements on cross-validation: The. 632-bootstrap method
    • Efron B, Tibshirani R. Improvements on cross-validation: the. 632-bootstrap method. JASA. 1997;92(4328):548-560.
    • (1997) JASA , vol.92 , Issue.4328 , pp. 548-560
    • Efron, B.1    Tibshirani, R.2
  • 25
    • 0029007706 scopus 로고
    • Tree-structured prediction for censored survival data and the Cox model
    • Ciampi A, Negassa A, Lou Z. Tree-structured prediction for censored survival data and the Cox model. J Clin Epidemiol. 1995;48(5):675-689.
    • (1995) J Clin Epidemiol. , vol.48 , Issue.5 , pp. 675-689
    • Ciampi, A.1    Negassa, A.2    Lou, Z.3
  • 27
    • 84855860383 scopus 로고    scopus 로고
    • NOTCH1 mutations in CLL associated with trisomy 12
    • Balatti V, Bottoni A, Palamarchuk A, et al. NOTCH1 mutations in CLL associated with trisomy 12. Blood. 2012;119(2):329-331.
    • (2012) Blood. , vol.119 , Issue.2 , pp. 329-331
    • Balatti, V.1    Bottoni, A.2    Palamarchuk, A.3
  • 28
    • 84857739865 scopus 로고    scopus 로고
    • NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL
    • Del Giudice I, Rossi D, Chiaretti S, et al. NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL. Haemato-logica. 2012;97(3):437-441.
    • (2012) Haematologica , vol.97 , Issue.3 , pp. 437-441
    • Del Giudice, I.1    Rossi, D.2    Chiaretti, S.3
  • 30
    • 36348953152 scopus 로고    scopus 로고
    • H status and immunophenotyping
    • DOI 10.1038/sj.leu.2404935, PII 2404935
    • Haferlach C, Dicker F, Schnittger S, Kern W, Haferlach T. Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV (H) status and immunophenotyping. Leukemia. 2007;21(12):2442-2451. (Pubitemid 350148886)
    • (2007) Leukemia , vol.21 , Issue.12 , pp. 2442-2451
    • Haferlach, C.1    Dicker, F.2    Schnittger, S.3    Kern, W.4    Haferlach, T.5
  • 31
    • 77949422979 scopus 로고    scopus 로고
    • Monoclonal B-cell lymphocytosis (MBL): Biology, natural history and clinical management
    • Shanafelt TD, Ghia P, Lanasa MC, Landgren O, Rawstron AC. Monoclonal B-cell lymphocytosis (MBL): biology, natural history and clinical management. Leukemia. 2010;24(3):512-520.
    • (2010) Leukemia. , vol.24 , Issue.3 , pp. 512-520
    • Shanafelt, T.D.1    Ghia, P.2    Lanasa, M.C.3    Landgren, O.4    Rawstron, A.C.5
  • 34
    • 36349025291 scopus 로고    scopus 로고
    • Clonal evolution in chronic lymphocytic leukemia: Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival
    • DOI 10.3324/haematol.10720
    • Stilgenbauer S, Sander S, Bullinger L, et al. Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival. Haematologica. 2007;92(9):1242-1245. (Pubitemid 350144184)
    • (2007) Haematologica , vol.92 , Issue.9 , pp. 1242-1245
    • Stilgenbauer, S.1    Sander, S.2    Bullinger, L.3    Benner, A.4    Leupolt, E.5    Winkler, D.6    Krober, A.7    Kienle, D.8    Lichter, P.9    Dohner, H.10
  • 35
    • 84861591789 scopus 로고    scopus 로고
    • Detectable clonal mosaicism from birth to old age and its relationship to cancer
    • Laurie CC, Laurie CA, Rice K, et al. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet. 2012;44(6):642-650.
    • (2012) Nat Genet. , vol.44 , Issue.6 , pp. 642-650
    • Laurie, C.C.1    Laurie, C.A.2    Rice, K.3
  • 36
    • 84861628224 scopus 로고    scopus 로고
    • Detectable clonal mosaicism and its relationship to aging and cancer
    • Jacobs KB, Yeager M, Zhou W, et al. Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet. 2012;44(6):651-658.
    • (2012) Nat Genet. , vol.44 , Issue.6 , pp. 651-658
    • Jacobs, K.B.1    Yeager, M.2    Zhou, W.3
  • 37
    • 80054691036 scopus 로고    scopus 로고
    • General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL
    • Fazi C, Scarfò L, Pecciarini L, et al. General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL. Blood. 2011;118(25):6618- 6625.
    • (2011) Blood. , vol.118 , Issue.25 , pp. 6618-6625
    • Fazi, C.1    Scarfò, L.2    Pecciarini, L.3
  • 38
    • 84870734255 scopus 로고    scopus 로고
    • Emerging role of kinase targeted strategies in chronic lymphocytic leukemia
    • Wiestner A. Emerging role of kinase targeted strategies in chronic lymphocytic leukemia. Blood. 2012;120(24):4684-4691.
    • (2012) Blood. , vol.120 , Issue.24 , pp. 4684-4691
    • Wiestner, A.1
  • 39
    • 84865082196 scopus 로고    scopus 로고
    • Novel targeted agents and the need to refine clinical end points in chronic lymphocytic leukemia
    • Cheson BD, Byrd JC, Rai KR, et al. Novel targeted agents and the need to refine clinical end points in chronic lymphocytic leukemia. J Clin Oncol. 2012;30(23):2820-2822.
    • (2012) J Clin Oncol. , vol.30 , Issue.23 , pp. 2820-2822
    • Cheson, B.D.1    Byrd, J.C.2    Rai, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.