-
4
-
-
0027953703
-
Insulin action, diabetogenes, and the cause of type II diabetes
-
(1994)
Diabetes
, vol.43
, pp. 1066-1084
-
-
Kahn, C.R.1
-
5
-
-
0023222361
-
Insulin receptor kinase in human skeletal muscle from obese subjects with and without non-insulin dependent diabetes
-
(1987)
J. Clin. Invest.
, vol.79
, pp. 1330-1337
-
-
Caro, J.F.1
-
8
-
-
0030890580
-
Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidyl inositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4171-4175
-
-
Rondinone, C.M.1
-
9
-
-
13344277357
-
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
-
(1996)
Nat. Genet.
, vol.12
, pp. 106-109
-
-
Accili, D.1
-
10
-
-
0029879127
-
Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality
-
(1996)
EMBO J.
, vol.15
, pp. 1542-1547
-
-
Joshi, R.L.1
-
11
-
-
0028032895
-
Alternative pathways of insulin signaling in mice with targeted disruption of the IRS-1 gene
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
-
12
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
-
13
-
-
0032567937
-
Disruption of IRS-2 causes type-2 diabetes in mice
-
(1998)
Nature
, vol.391
, pp. 900-903
-
-
Withers, D.J.1
-
14
-
-
0032841435
-
Irs-2 coordinates Igf-1 receptor-mediated betacell development and peripheral insulin signaling
-
(1999)
Nat. Genet.
, vol.23
, pp. 32-40
-
-
Withers, D.J.1
-
15
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Bruning, J.C.1
-
16
-
-
0033966768
-
Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 199-205
-
-
Kido, Y.1
-
17
-
-
0032214652
-
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
-
(1998)
Mol. Cell.
, vol.2
, pp. 559-569
-
-
Bruning, J.C.1
-
18
-
-
0033636523
-
Loss of insulin signaling in heparocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
(2000)
Mol. Cell.
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
-
19
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type II diabetes
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
-
20
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
-
25
-
-
0033213631
-
PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro
-
(1999)
Mol. Cell.
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
-
27
-
-
0033083803
-
Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
-
(1999)
Mol. Cell.
, vol.3
, pp. 151-158
-
-
Wu, Z.1
-
28
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is the major link between obesity, β cell dysfunction, and type-2 diabetes
-
(2001)
Cell
, vol.105
, pp. 745-755
-
-
Zhang, C.Y.1
-
30
-
-
0030610147
-
3-selective agonist-induced effects on energy expenditure, insulin secretion and food intake
-
(1997)
J. Biol. Chem.
, vol.28
, pp. 17686-17693
-
-
Grujic, D.1
-
31
-
-
0032532753
-
Life without white fat: A transgenic mouse
-
(1998)
Genes Dev.
, vol.12
, pp. 3168-3181
-
-
Moitra, J.1
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