Activity of Bradykinin B2 Receptor Is Regulated by Long-Chain Polyunsaturated Fatty Acids

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Candelario, Jose ^a   Chachisvilis, Mirianas ^a  

^a LA JOLLA BIOENGINEERING INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; BRADYKININ B2 RECEPTOR; BRADYKININ B2 RECEPTOR ANTAGONIST; DIHOMO GAMMA LINOLENIC ACID; DOCOSADIENOIC ACID; DOCOSAHEXAENOIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ICATIBANT; ICOSAPENTAENOIC ACID; KRUPPEL LIKE FACTOR 2; LONG CHAIN FATTY ACID; MITOGEN ACTIVATED PROTEIN KINASE; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG; KLF2 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; NOS3 PROTEIN, HUMAN; UNSATURATED FATTY ACID;

ARTICLE; BILAYER MEMBRANE; CARDIOVASCULAR SYSTEM; CHEMICAL BOND; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLUORESCENCE MICROSCOPY; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MEMBRANE FLUIDITY; PROTEIN CONFORMATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; BOVINE; CELL MEMBRANE; CORONARY BLOOD VESSEL; CYTOLOGY; ENDOTHELIUM CELL; GENETICS; HEK293 CELL LINE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; VISCOSITY;

ANIMALS; AORTA; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONISTS; CATTLE; CELL MEMBRANE; CORONARY VESSELS; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY ACIDS, UNSATURATED; HEK293 CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN CONFORMATION; RECEPTOR, BRADYKININ B2; SIGNAL TRANSDUCTION; VISCOSITY;

EID: 84879539821     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068151     Document Type: Article

References (69)

1. Candelario J, Tavakoli H, Chachisvilis M, (2012) PTH1 receptor is involved in mediating cellular response to long-chain polyunsaturated fatty acids. PLoS One 7: e52583.
2. Poole KE, Reeve J, (2005) Parathyroid hormone- a bone anabolic and catabolic agent. Curr Opin Pharmacol 5: 612-617.
3. Kenakin T, (2004) G-protein coupled receptors as allosteric machines. Receptors Channels 10: 51-60.
4. Kenakin TP, (2012) Biased signalling and allosteric machines: new vistas and challenges for drug discovery. Br J Pharmacol 165: 1659-1669.
5. Liu W, Chun E, Thompson AA, Chubukov P, Xu F, et al. (2012) Structural basis for allosteric regulation of GPCRs by sodium ions. Science 337: 232-236.
6. Canals M, Sexton PM, Christopoulos A, (2011) Allostery in GPCRs: 'MWC' revisited. Trends Biochem Sci 36: 663-672.
7. Changeux JP, (2012) Allostery and the Monod-Wyman-Changeux model after 50 years. Annu Rev Biophys 41: 103-133.
8. Storch U, Mederos y Schnitzler M, Gudermann T, (2012) G protein-mediated stretch reception. Am J Physiol Heart Circ Physiol 302: H1241-1249.
9. Zhang YL, Frangos JA, Chachisvilis M, (2009) Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells. American Journal of Physiology-Cell Physiology 296: C1391-C1399.
10. Candelario J, Chachisvilis M, (2012) Mechanical Stress Stimulates Conformational Changes in 5-Hydroxytryptamine Receptor 1B in Bone Cells. Cellular and Molecular Bioengineering 5: 277-286.
11. Leeb-Lundberg LMF, Marceau F, Muller-Esterl W, Pettibone DJ, Zuraw BL, (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacological Reviews 57: 27-77.
12. Chachisvilis M, Zhang YL, Frangos JA, (2006) G protein-coupled receptors sense fluid shear stress in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America 103: 15463-15468.
13. Palmer RM, Ferrige AG, Moncada S, (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526.
14. Naseem KM, (2005) The role of nitric oxide in cardiovascular diseases. Mol Aspects Med 26: 33-65.
15. Yin K, Chu ZM, Beilin LJ, (1991) Blood pressure and vascular reactivity changes in spontaneously hypertensive rats fed fish oil. Br J Pharmacol 102: 991-997.
16. Lawson DL, Mehta JL, Saldeen K, Mehta P, Saldeen TG, (1991) Omega-3 polyunsaturated fatty acids augment endothelium-dependent vasorelaxation by enhanced release of EDRF and vasodilator prostaglandins. Eicosanoids 4: 217-223.
17. Engler MB, Engler MM, Browne A, Sun YP, Sievers R, (2000) Mechanisms of vasorelaxation induced by eicosapentaenoic acid (20:5n-3) in WKY rat aorta. Br J Pharmacol 131: 1793-1799.
18. Engler MB, Engler MM, Ursell PC, (1994) Vasorelaxant properties of n-3 polyunsaturated fatty acids in aortas from spontaneously hypertensive and normotensive rats. J Cardiovasc Risk 1: 75-80.
19. Tagawa H, Shimokawa H, Tagawa T, Kuroiwa-Matsumoto M, Hirooka Y, et al. (1999) Long-term treatment with eicosapentaenoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease. J Cardiovasc Pharmacol 33: 633-640.
20. Omura M, Kobayashi S, Mizukami Y, Mogami K, Todoroki-Ikeda N, et al. (2001) Eicosapentaenoic acid (EPA) induces Ca(2+)-independent activation and translocation of endothelial nitric oxide synthase and endothelium-dependent vasorelaxation. FEBS Lett 487: 361-366.
21. Hamilton JA, Kamp F, (1999) How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids? Diabetes 48: 2255-2269.
22. Salem Jr N, Kim H.-Y., Yergey J.A., (1986) Docosahexaenoic acid: Membrane function and metabolism.
23. VanMeter AR, Ehringer WD, Stillwell W, Blumenthal EJ, Jenski LJ, (1994) Aged lymphocyte proliferation following incorporation and retention of dietary omega-3 fatty acids. Mechanisms of ageing and development 75: 95-114.
24. Robinson DR, Xu LL, Knoell CT, Tateno S, Olesiak W, (1993) Modification of spleen phospholipid fatty acid composition by dietary fish oil and by n-3 fatty acid ethyl esters. Journal of Lipid Research 34: 1423-1434.
25. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, et al. (2002) Blood levels of long-chain n-3 fatty acids and the risk of sudden death. The New England journal of medicine 346: 1113-1118.
26. Leone TC, Weinheimer CJ, Kelly DP, (1999) A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proceedings of the National Academy of Sciences of the United States of America 96: 7473-7478.
27. Fan YY, McMurray DN, Ly LH, Chapkin RS, (2003) Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts. The Journal of nutrition 133: 1913-1920.
28. Bruno MJ, Koeppe RE 2nd, Andersen OS, (2007) Docosahexaenoic acid alters bilayer elastic properties. Proc Natl Acad Sci U S A 104: 9638-9643.
29. Starke-Peterkovic T, Turner N, Else PL, Clarke RJ, (2005) Electric field strength of membrane lipids from vertebrate species: Membrane lipid composition and Na+-K+-ATPase molecular activity. American journal of physiology Regulatory, integrative and comparative physiology 288: R663-670.
30. Muslin AJ, (2008) MAPK signalling in cardiovascular health and disease: Molecular mechanisms and therapeutic targets. Clin Sci (Lond) 115: 203-218.
31. Lohse MJ, Bunemann M, Hoffmann C, Vilardaga JP, Nikolaev VO, (2007) Monitoring receptor signaling by intramolecular FRET. Curr Opin Pharmacol 7: 547-553.
32. Castro M, Nikolaev VO, Palm D, Lohse MJ, Vilardaga JP, (2005) Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism. Proceedings of the National Academy of Sciences of the United States of America 102: 16084-16089.
33. Vilardaga JP, Bunemann M, Krasel C, Castro M, Lohse MJ, (2003) Measurement of the millisecond activation switch of G protein-coupled receptors in living cells. Nat Biotechnol 21: 807-812.
34. Zurn A, Zabel U, Vilardaga JP, Schindelin H, Lohse MJ, et al. (2009) Fluorescence resonance energy transfer analysis of alpha 2a-adrenergic receptor activation reveals distinct agonist-specific conformational changes. Mol Pharmacol 75: 534-541.
35. Hoffmann C, Gaietta G, Bunemann M, Adams SR, Oberdorff-Maass S, et al. (2005) A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nat Methods 2: 171-176.
36. Candelario J, Chachisvilis M (2012) Mechanical Stress Stimulates Conformational Changes in 5-Hydroxytryptamine Receptor 1B in Bone Cells. Cellular and Molecular Bioengineering: In print.
37. Trifilieff A, Da Silva A, Landry Y, Gies JP, (1992) Effect of Hoe 140, a new B2 noncompetitive antagonist, on guinea pig tracheal bradykinin receptors. J Pharmacol Exp Ther 263: 1377-1382.
38. Vilardaga JP, Steinmeyer R, Harms GS, Lohse MJ, (2005) Molecular basis of inverse agonism in a G protein-coupled receptor. Nat Chem Biol 1: 25-28.
39. Thomas P, Smart TG, (2005) HEK293 cell line: a vehicle for the expression of recombinant proteins. Journal of pharmacological and toxicological methods 51: 187-200.
40. Kramarenko, II, Bunni MA, Morinelli TA, Raymond JR, Garnovskaya MN, (2009) Identification of functional bradykinin B(2) receptors endogenously expressed in HEK293 cells. Biochem Pharmacol 77: 269-276.
41. Klausner RD, Kleinfeld AM, Hoover RL, Karnovsky MJ, (1980) Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysis. J Biol Chem 255: 1286-1295.
42. Otto JC, Smith WL, (1994) The orientation of prostaglandin endoperoxide synthases-1 and-2 in the endoplasmic reticulum. J Biol Chem 269: 19868-19875.
43. Saito J, Terano T, Hirai A, Shiina T, Tamura Y, et al. (1997) Mechanisms of enhanced production of PGI2 in cultured rat vascular smooth muscle cells enriched with eicosapentaenoic acid. Atherosclerosis 131: 219-228.
44. Kulmacz RJ, Pendleton RB, Lands WE, (1994) Interaction between peroxidase and cyclooxygenase activities in prostaglandin-endoperoxide synthase. Interpretation of reaction kinetics. J Biol Chem 269: 5527-5536.
45. Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, et al. (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399: 601-605.
46. SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, et al. (2004) KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation. J Exp Med 199: 1305-1315.
47. Haidekker MA, Ling TT, Anglo M, Stevens HY, Frangos JA, et al. (2001) New fluorescent probes for the measurement of cell membrane viscosity. Chemistry & Biology 8: 123-131.
48. Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, et al. (2003) The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278: 11312-11319.
49. Le Poul E, Loison C, Struyf S, Springael JY, Lannoy V, et al. (2003) Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 278: 25481-25489.
50. Wang J, Wu X, Simonavicius N, Tian H, Ling L, (2006) Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84. J Biol Chem 281: 34457-34464.
51. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, et al. (2005) Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11: 90-94.
52. Arunlakshana O, Schild HO, (1959) Some quantitative uses of drug antagonists. Br J Pharmacol Chemother 14: 48-58.
53. Wyllie DJ, Chen PE, (2007) Taking the time to study competitive antagonism. Br J Pharmacol 150: 541-551.
54. Wu Y, Zhang C, Dong Y, Wang S, Song P, et al. (2012) Activation of the AMP-activated protein kinase by eicosapentaenoic acid (EPA, 20:5 n-3) improves endothelial function in vivo. PLoS One 7: e35508.
55. Dekker RJ, van Soest S, Fontijn RD, Salamanca S, de Groot PG, et al. (2002) Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2). Blood 100: 1689-1698.
56. Friedman MH, O'Brien V, Ehrlich LW, (1975) Calculations of pulsatile flow through a branch: Implications for the hemodynamics of atherogenesis. Circ Res 36: 277-285.
57. Tarlton JF, Wilkins LJ, Toscano MJ, Avery NC, Knott L, (2013) Reduced bone breakage and increased bone strength in free range laying hens fed omega-3 polyunsaturated fatty acid supplemented diets. Bone 52: 578-586.
58. Gudi S, Nolan JP, Frangos JA, (1998) Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition. Proceedings of the National Academy of Sciences of the United States of America 95: 2515-2519.
59. Turchiello RF, Juliano L, Ito AS, Lamy-Freund MT, (2000) How bradykinin alters the lipid membrane structure: a spin label comparative study with bradykinin fragments and other cations. Biopolymers 54: 211-221.
60. Thompson AA, Liu JJ, Chun E, Wacker D, Wu H, et al. (2011) GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods 55: 310-317.
61. Figueroa CD, Marchant A, Novoa U, Forstermann U, Jarnagin K, et al. (2001) Differential Distribution of Bradykinin B(2) Receptors in the Rat and Human Cardiovascular System. Hypertension 37: 110-120.
62. Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, et al. (2010) GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 142: 687-698.
63. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354: 447-455.
64. Baylin A, Kabagambe EK, Ascherio A, Spiegelman D, Campos H, (2003) Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Rica. Circulation 107: 1586-1591.
65. Hu FB, Bronner L, Willett WC, Stampfer MJ, Rexrode KM, et al. (2002) Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA 287: 1815-1821.
66. De Caterina R, (2011) n-3 fatty acids in cardiovascular disease. N Engl J Med 364: 2439-2450.
67. Zhang YL, Frangos JA, Chachisvilis M, (2009) Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells. Am J Physiol-Cell Ph 296: C1391-C1399.
68. Zacharias DA, Violin JD, Newton AC, Tsien RY, (2002) Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 296: 913-916.
69. Chachisvilis M, Zhang YL, Frangos JA, (2006) G protein-coupled receptors sense fluid shear stress in endothelial cells. Proc Natl Acad Sci U S A 103: 15463-15468.