Transgenic Increase in N-3/N-6 Fatty Acid Ratio Reduces Maternal Obesity-Associated Inflammation and Limits Adverse Developmental Programming in Mice

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Heerwagen, Margaret J R ^a   Stewart, Michael S ^a   de la Houssaye, Becky A ^a   Janssen, Rachel C ^a   Friedman, Jacob E ^a,b  

^a Children's Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE ASSOCIATION; FAT 1 GENE; FATTY ACID BLOOD LEVEL; FEMALE; FETUS; FETUS GROWTH; FETUS OUTCOME; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID STORAGE; LIPID TRANSPORT; LITTER SIZE; MACROPHAGE; MALE; MATERNAL OBESITY; MOUSE; NONHUMAN; PLACENTA WEIGHT; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSGENE; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ANIMALS; DIET, HIGH-FAT; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FEMALE; FETUS; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTHERS; OBESITY; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS;

MUS; MUS MUSCULUS;

EID: 84879375197     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067791     Document Type: Article

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