Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A

Journal of Nutritional Biochemistry

Volumn 24, Issue 1, 2013, Pages 6-13

  Burgueño, Adriana Laura ^a   Cabrerizo, Romina ^a   Gonzales Mansilla, Noelia ^a   Sookoian, Silvia ^a   Pirola, Carlos Jose ^a  

^a INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

Gene expression; High fat diet; Insulin resistance; Liver; Metabolic programming; Mitochondrial copy number; Mitochondrial DNA; NAFLD; PGC1a; PPARGC1a

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR NRF1;

ABDOMINAL FAT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FATTY LIVER; FEMALE; GENE DOSAGE; HYPERLEPTINEMIA; INSULIN RESISTANCE; LACTATION; LIPID DIET; LIPID STORAGE; LIVER MITOCHONDRION; MALE; MATERNAL NUTRITION; METABOLIC SYNDROME X; NONHUMAN; PHENOTYPE; PREGNANCY; PROGENY; PROTEIN EXPRESSION; RAT;

ANIMALS; BODY WEIGHT; DIET, HIGH-FAT; DNA, MITOCHONDRIAL; FEMALE; GENE DOSAGE; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 4; INSULIN RESISTANCE; LIVER; MALE; METABOLIC SYNDROME X; PHENOTYPE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS, WISTAR; RNA-BINDING PROTEINS; SEX FACTORS; TRANSCRIPTION FACTORS;

RATTUS;

EID: 84870477112     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.12.008     Document Type: Article

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