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Volumn 949, Issue , 2013, Pages 305-334

Applications of micro fluidics for molecular diagnostics

Author keywords

Biomarker detection; Global health care; Lab on A chip; Mems; Micro fluidics; Micro total Analysis systems; Personalized medicine; Point of care devices; Rapid prototyping; Sample preparation

Indexed keywords

ANTIVIRUS AGENT; BIOCHEMICAL MARKER; POLYMER; TUMOR MARKER;

EID: 84879309801     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-134-9_20     Document Type: Article
Times cited : (48)

References (168)
  • 2
    • 70349972114 scopus 로고    scopus 로고
    • Point-of-care testing and molecular diagnostics: Miniaturization required
    • Kiechle FL, Holland CA (2009) Point-of-Care Testing and Molecular Diagnostics: Miniaturization Required. Clin Lab Med 29(3):555-560
    • (2009) Clin Lab Med , vol.29 , Issue.3 , pp. 555-560
    • Kiechle, F.L.1    Holland, C.A.2
  • 6
    • 8444244790 scopus 로고    scopus 로고
    • Multiplex diagnostic platforms for detection of biothreat agents
    • Cirino NM, Musser KA, Egan C (2004) Multiplex diagnostic platforms for detection of biothreat agents. Expert Rev Mol Diagn 4:841-857
    • (2004) Expert Rev Mol Diagn , vol.4 , pp. 841-857
    • Cirino, N.M.1    Musser, K.A.2    Egan, C.3
  • 7
    • 84892911843 scopus 로고    scopus 로고
    • National select agent registry: Overview
    • USDA U S D o HHS H a A (ed) , Washington DC
    • U S D o HHS H a A (ed) (2011) National select agent registry: overview. Department of Health & Human Service, Washington DC
    • (2011) Department of Health & Human Service
  • 8
    • 84929559168 scopus 로고    scopus 로고
    • Recommendations: Clinical laboratory improvement amendments of 1988 (clia waiver applications for manufacturers of in vitro diagnostic devices
    • Food and Drug Administration (2008) Recommendations: Clinical Laboratory Improvement Amendments of 1988 (CLIA Waiver Applications for Manufacturers of In Vitro Diagnostic Devices.
    • (2008) Food and Drug Administration
  • 9
    • 56549111261 scopus 로고    scopus 로고
    • Micro fluidics and point-of-care testing
    • Sia SK, Kricka LJ (2008) Micro fluidics and point-of-care testing. Lab Chip 8:1982-1983
    • (2008) Lab Chip , vol.8 , pp. 1982-1983
    • Sia, S.K.1    Kricka, L.J.2
  • 10
    • 33747117373 scopus 로고    scopus 로고
    • The origins and the future of micro fluidics
    • Whitesides GM (2006) The origins and the future of micro fluidics. Nature 442:368-373
    • (2006) Nature , vol.442 , pp. 368-373
    • Whitesides, G.M.1
  • 11
    • 77953576255 scopus 로고    scopus 로고
    • Latest developments in micro total analysis systems
    • Arora A et al (2010) Latest developments in micro total analysis systems. Anal Chem 82:4830-4847
    • (2010) Anal Chem , vol.82 , pp. 4830-4847
    • Arora, A.1
  • 12
    • 77953571969 scopus 로고    scopus 로고
    • Latest developments in micro fluidic cell biology and analysis systems
    • Salieb-Beugelaar GB et al (2010) Latest developments in micro fluidic cell biology and analysis systems. Anal Chem 82:4848-4864
    • (2010) Anal Chem , vol.82 , pp. 4848-4864
    • Salieb-Beugelaar, G.B.1
  • 13
    • 45249090842 scopus 로고    scopus 로고
    • Micro total analysis systems: Latest achievements
    • West J et al (2008) Micro total analysis systems: latest achievements. Anal Chem 80:4403-4419
    • (2008) Anal Chem , vol.80 , pp. 4403-4419
    • West, J.1
  • 15
    • 4644335402 scopus 로고    scopus 로고
    • Systems biology, proteomics, and the future of health care: Toward predictive, preventative, and personalized medicine
    • Weston AD, Hood L (2004) Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine. J Proteome Res 3:179-196
    • (2004) J Proteome Res , vol.3 , pp. 179-196
    • Weston, A.D.1    Hood, L.2
  • 16
    • 0037096666 scopus 로고    scopus 로고
    • Micro total analysis systems 1 introduction
    • Reyes DR (2002) Micro Total Analysis Systems. 1. Introduction. Theory, and Technology 74(12):2623-2636
    • (2002) Theory, and Technology , vol.74 , Issue.12 , pp. 2623-2636
    • Reyes, D.R.1
  • 17
    • 0029342320 scopus 로고
    • Fused quartz substrates for microchip electrophoresis
    • Jacobson SC, Moore AW, Ramsey JM (1995) Fused quartz substrates for microchip electrophoresis. Anal Chem 67:2059-2063
    • (1995) Anal Chem , vol.67 , pp. 2059-2063
    • Jacobson, S.C.1    Moore, A.W.2    Ramsey, J.M.3
  • 18
    • 0030176647 scopus 로고    scopus 로고
    • Micellar electrokinetic chromatography separations and analyses of biological samples on a cyclic planar microstructure
    • von Heeren F et al (1996) Micellar electrokinetic chromatography separations and analyses of biological samples on a cyclic planar microstructure. Anal Chem 68:2044-2053
    • (1996) Anal Chem , vol.68 , pp. 2044-2053
    • Von Heeren, F.1
  • 19
    • 0029394999 scopus 로고
    • Microchip separations of neutral species via micellar electrokinetic capillary chromatography
    • Moore AW Jr, Jacobson SC, Ramsey JM (1995) Microchip separations of neutral species via micellar electrokinetic capillary chromatography. Anal Chem 67:4184-4189
    • (1995) Anal Chem , vol.67 , pp. 4184-4189
    • Moore, Jr.A.W.1    Jacobson, S.C.2    Ramsey, J.M.3
  • 20
    • 0029645606 scopus 로고
    • Ultra-highspeed DNA sequencing using capillary electrophoresis chips
    • Woolley AT, Mathies RA (1995) Ultra-highspeed DNA sequencing using capillary electrophoresis chips. Anal Chem 67:3676-3680
    • (1995) Anal Chem , vol.67 , pp. 3676-3680
    • Woolley, A.T.1    Mathies, R.A.2
  • 21
    • 0029918709 scopus 로고    scopus 로고
    • Chip pcr i surface passivation of microfabricated siliconglass chips for pcr
    • Shoffner MA et al (1996) Chip PCR. I. Surface passivation of microfabricated siliconglass chips for PCR. Nucleic Acids Res 24:375-379
    • (1996) Nucleic Acids Res , vol.24 , pp. 375-379
    • Shoffner, M.A.1
  • 22
    • 0029692711 scopus 로고    scopus 로고
    • Microchip electrophoretic immunoassay for serum cortisol
    • Koutny LB et al (1996) Microchip electrophoretic immunoassay for serum cortisol. Anal Chem 68:18-22
    • (1996) Anal Chem , vol.68 , pp. 18-22
    • Koutny, L.B.1
  • 23
    • 0031215263 scopus 로고    scopus 로고
    • Microchip device for performing enzyme assays
    • Hadd AG et al (1997) Microchip device for performing enzyme assays. Anal Chem 69:3407-3412
    • (1997) Anal Chem , vol.69 , pp. 3407-3412
    • Hadd, A.G.1
  • 24
    • 0030670283 scopus 로고    scopus 로고
    • Microchip-based capillary electrophoresis of human serum proteins
    • Colyer CL, Mangru SD, Harrison DJ (1997) Microchip-based capillary electrophoresis of human serum proteins. J Chromatogr A 781:271-276
    • (1997) J Chromatogr A , vol.781 , pp. 271-276
    • Colyer, C.L.1    Mangru, S.D.2    Harrison, D.J.3
  • 25
    • 0001574968 scopus 로고    scopus 로고
    • Continuous separation of high molecular weight compounds using a microliter volume free-flow electrophoresis microstructure
    • Raymond DE, Manz A, Widmer HM (1996) Continuous separation of high molecular weight compounds using a microliter volume free-flow electrophoresis microstructure. Anal Chem 68:2515-2522
    • (1996) Anal Chem , vol.68 , pp. 2515-2522
    • Raymond, D.E.1    Manz, A.2    Widmer, H.M.3
  • 26
    • 1542525846 scopus 로고    scopus 로고
    • Characterization of electrophoretic sample injection and separation in a gel fi lled cyclic planar microstructure
    • von Heeren F et al (1996) Characterization of electrophoretic sample injection and separation in a gel fi lled cyclic planar microstructure. J Microcolumn Separations 8:373-381
    • (1996) J Microcolumn Separations , vol.8 , pp. 373-381
    • Von Heeren, F.1
  • 27
    • 4244166752 scopus 로고    scopus 로고
    • High-speed dna genotyping using microfabricated capillary array electrophoresis chips
    • Woolley AT, Sensabaugh GF, Mathies RA (1997) High-speed DNA genotyping using microfabricated capillary array electrophoresis chips. Anal Chem 69:2181-2186
    • (1997) Anal Chem , vol.69 , pp. 2181-2186
    • Woolley, A.T.1    Sensabaugh, G.F.2    Mathies, R.A.3
  • 28
    • 0030948781 scopus 로고    scopus 로고
    • Patterned delivery of immunoglobulins to surfaces using micro fluidic networks
    • Delamarche E et al (1997) Patterned delivery of immunoglobulins to surfaces using micro fluidic networks. Science 276:779
    • (1997) Science , vol.276 , pp. 779
    • Delamarche, E.1
  • 29
    • 18544392190 scopus 로고    scopus 로고
    • Novel instrumentation for real-time monitoring using miniaturized flow systems with integrated biosensors
    • Freaney R et al (1997) Novel instrumentation for real-time monitoring using miniaturized flow systems with integrated biosensors. Ann Clin Biochem 34:291-302
    • (1997) Ann Clin Biochem , vol.34 , pp. 291-302
    • Freaney, R.1
  • 30
    • 0025207507 scopus 로고
    • Miniaturized total chemical analysis systems: A novel concept for chemical sensing
    • Manz A, Graber N, Widmer HM (1990) Miniaturized total chemical analysis systems: a novel concept for chemical sensing. Sensors Actuators B: Chemical 1:244-248
    • (1990) Sensors Actuators B: Chemical , vol.1 , pp. 244-248
    • Manz, A.1    Graber, N.2    Widmer, H.M.3
  • 31
    • 0026407181 scopus 로고
    • Electroosmotic pumping within a chemical sensor system integrated on silicon. in
    • Transducers '91 San Francisco, USA
    • Harrison DJ, Manz A, Glavina PG (1991) Electroosmotic pumping within a chemical sensor system integrated on silicon. In: Proc. IEEE Int. Conf. Solid-State Sensors and Actuators (Transducers '91), San Francisco, USA, pp 792-795
    • (1991) Proc. IEEE Int. Conf. Solid-State Sensors and Actuators , pp. 792-795
    • Harrison, D.J.1    Manz, A.2    Glavina, P.G.3
  • 32
    • 0000705576 scopus 로고
    • Planar glass chips for capillary electrophoresis: Repetitive sample injection, quantitation, and separation efficiency
    • Seiler K, Harrison DJ, Manz A (1993) Planar glass chips for capillary electrophoresis: repetitive sample injection, quantitation, and separation efficiency. Anal Chem 65: 1481-1488
    • (1993) Anal Chem , vol.65 , pp. 1481-1488
    • Seiler, K.1    Harrison, D.J.2    Manz, A.3
  • 33
    • 0027186801 scopus 로고
    • A microfabricated flow chamber for optical measurements in fluids
    • USA
    • Sobek D et al. (1993) A microfabricated flow chamber for optical measurements in fluids. In: Proc. 6th IEEE MEMS, Fort Lauderdale, USA, pp 219-224
    • (1993) Proc. 6th IEEE MEMS, Fort Lauderdale , pp. 219-224
    • Sobek, D.1
  • 34
    • 0001878651 scopus 로고
    • DNA ampli fication with a microfabricated reaction chamber
    • Transducers '93 Yokohama, Japan
    • Northrup MA et al. (1993) DNA ampli fication with a microfabricated reaction chamber. In: Proc. of The 7th Int. Conf. on Solid-State Sensors and Actuators (Transducers '93), Yokohama, Japan, pp 924-926
    • (1993) Proc. of the 7th Int. Conf. on Solid-State Sensors and Actuators , pp. 924-926
    • Northrup, M.A.1
  • 35
    • 0028443982 scopus 로고
    • Micromachined multichannel systems for the measurement of cellular metabolism
    • Bousse L et al (1994) Micromachined multichannel systems for the measurement of cellular metabolism. Sensors Actuators B: Chemical 20:145-150
    • (1994) Sensors Actuators B: Chemical , vol.20 , pp. 145-150
    • Bousse, L.1
  • 36
    • 0001725611 scopus 로고
    • Precolumn reactions with electrophoretic analysis integrated on a microchip
    • Jacobson SC et al (1994) Precolumn reactions with electrophoretic analysis integrated on a microchip. Anal Chem 66:4127-4132
    • (1994) Anal Chem , vol.66 , pp. 4127-4132
    • Jacobson, S.C.1
  • 37
    • 0001242036 scopus 로고
    • Microchip capillary electrophoresis with an integrated postcolumn reactor
    • Jacobson SC et al (1994) Microchip capillary electrophoresis with an integrated postcolumn reactor. Anal Chem 66:3472-3476
    • (1994) Anal Chem , vol.66 , pp. 3472-3476
    • Jacobson, S.C.1
  • 38
    • 0028409726 scopus 로고
    • High-speed separations on a microchip
    • Jacobson SC et al (1994) High-speed separations on a microchip. Anal Chem 66: 1114-1118
    • (1994) Anal Chem , vol.66 , pp. 1114-1118
    • Jacobson, S.C.1
  • 39
    • 0002975605 scopus 로고
    • Microreactor with integrated static mixer and analysis system
    • Kluwer Academic Publishers
    • Mensinger H et al (1995) Microreactor with integrated static mixer and analysis system. Kluwer Academic Publishers, The Netherlands, p 237
    • (1995) The Netherlands , pp. 237
    • Mensinger, H.1
  • 40
    • 0027967658 scopus 로고
    • High-speed separation of antisense oligonucleotides on a micromachined capillary electrophoresis device
    • Effenhauser CS et al (1994) High-speed separation of antisense oligonucleotides on a micromachined capillary electrophoresis device. Anal Chem 66:2949-2953
    • (1994) Anal Chem , vol.66 , pp. 2949-2953
    • Effenhauser, C.S.1
  • 41
    • 0027987997 scopus 로고
    • Ultra-highspeed DNA fragment separations using microfabricated capillary array electrophoresis chips
    • Woolley AT, Mathies RA (1994) Ultra-highspeed DNA fragment separations using microfabricated capillary array electrophoresis chips. Proc Natl Acad Sci 91:11348
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 11348
    • Woolley, A.T.1    Mathies, R.A.2
  • 42
    • 0000004795 scopus 로고
    • Micromachining of capillary electrophoresis injectors and separators on glass chips and evaluation of flow at capillary intersections
    • Fan ZH, Harrison DJ (1994) Micromachining of capillary electrophoresis injectors and separators on glass chips and evaluation of flow at capillary intersections. Anal Chem 66:177-184
    • (1994) Anal Chem , vol.66 , pp. 177-184
    • Zh, F.1    Harrison, D.J.2
  • 43
    • 84892918172 scopus 로고
    • Electric field mediated cell manipulation, characterisation and cultivation in highly conductive media
    • University of Twente, Netherlands, 21-22 Nov 1994
    • Fuhr G, and Wagner B. (1994) Electric field mediated cell manipulation, characterisation and cultivation in highly conductive media. Paper presented at the MicroTAS, University of Twente, Netherlands, 21-22 Nov 1994
    • (1994) Paper Presented at the MicroTAS
    • Fuhr, G.1    Wagner, B.2
  • 44
    • 0028699978 scopus 로고
    • Electroosmotic pumping and electrophoretic separations for miniaturized chemical analysis systems
    • Manz A et al (1994) Electroosmotic pumping and electrophoretic separations for miniaturized chemical analysis systems. J Micromech Microeng 4:257
    • (1994) J Micromech Microeng , vol.4 , pp. 257
    • Manz, A.1
  • 45
    • 0000924121 scopus 로고
    • Continuous sample pretreatment using a freeflow electrophoresis device integrated onto a silicon chip
    • Raymond DE, Manz A, Widmer HM (1994) Continuous sample pretreatment using a freeflow electrophoresis device integrated onto a silicon chip. Anal Chem 66:2858-2865
    • (1994) Anal Chem , vol.66 , pp. 2858-2865
    • Raymond, D.E.1    Manz, A.2    Widmer, H.M.3
  • 46
    • 0028728130 scopus 로고
    • Threedimensional micro flow manifolds for miniaturized chemical analysis systems
    • Verpoorte EMJ et al (1994) Threedimensional micro flow manifolds for miniaturized chemical analysis systems. J Micromech Microeng 4:246
    • (1994) J Micromech Microeng , vol.4 , pp. 246
    • Emj, V.1
  • 47
    • 12044249341 scopus 로고
    • Electroosmotic pumping and valveless control of fluid flow within a manifold of capillaries on a glass chip
    • Seiler K et al (1994) Electroosmotic pumping and valveless control of fluid flow within a manifold of capillaries on a glass chip. Anal Chem 66:3485-3491
    • (1994) Anal Chem , vol.66 , pp. 3485-3491
    • Seiler, K.1
  • 48
    • 0028478902 scopus 로고
    • Open channel electrochromatography on a microchip
    • Jacobson SC et al (1994) Open channel electrochromatography on a microchip. Anal Chem 66:2369-2373
    • (1994) Anal Chem , vol.66 , pp. 2369-2373
    • Jacobson, S.C.1
  • 50
    • 0029357345 scopus 로고
    • Polymer microstructures formed by moulding in capillaries
    • Kim E, Xia Y, Whitesides GM (1995) Polymer microstructures formed by moulding in capillaries. Nature 376:581-584
    • (1995) Nature , vol.376 , pp. 581-584
    • Kim, E.1    Xia, Y.2    Whitesides, G.M.3
  • 52
    • 0034802766 scopus 로고    scopus 로고
    • Soft lithography in biology and biochemistry
    • Whitesides GM et al (2001) Soft lithography in biology and biochemistry. Annu Rev Biomed Eng 3:335-373
    • (2001) Annu Rev Biomed Eng , vol.3 , pp. 335-373
    • Whitesides, G.M.1
  • 53
    • 0029311118 scopus 로고
    • Patterning self-Assembled monolayers using microcontact printing: A new technology for biosensors?
    • Mrksich M, Whitesides GM (1995) Patterning self-Assembled monolayers using microcontact printing: a new technology for biosensors? Trends Biotechnol 13:228-235
    • (1995) Trends Biotechnol , vol.13 , pp. 228-235
    • Mrksich, M.1    Whitesides, G.M.2
  • 54
    • 0030263409 scopus 로고    scopus 로고
    • Fabrication of three dimensional micro structures: Microtransfer molding
    • Zhao XM, Xia Y, Whitesides GM (1996) Fabrication of three dimensional micro structures: Microtransfer molding. Adv Mater 8:837-840
    • (1996) Adv Mater , vol.8 , pp. 837-840
    • Zhao, X.M.1    Xia, Y.2    Whitesides, G.M.3
  • 56
    • 84892932508 scopus 로고    scopus 로고
    • In Gianchandani YB, Tabata O, Zappe HP (eds) Comprehensive microsystems Elsevier, Amsterdam
    • Gale BK et al (2008) Fabrication and packaging: Low-cost MEMS technologies. In: Gianchandani YB, Tabata O, Zappe HP (eds) Comprehensive microsystems. Elsevier, Amsterdam, pp 341-378
    • (2008) Fabrication and Packaging: Low-cost MEMS Technologies , pp. 341-378
    • Gale, B.K.1
  • 57
    • 0031308143 scopus 로고    scopus 로고
    • Fabrication of plastic micro fluid channels by imprinting methods
    • Martynova L et al (1997) Fabrication of plastic micro fluid channels by imprinting methods. Anal Chem 69:4783-4789
    • (1997) Anal Chem , vol.69 , pp. 4783-4789
    • Martynova, L.1
  • 58
    • 0032089654 scopus 로고    scopus 로고
    • Fluidic interconnects for modular assembly of chemical microsystems
    • Gonzalez C, Collins SD, Smith RL (1998) Fluidic interconnects for modular assembly of chemical microsystems. Sens. Actuators B: Chemical 49:40-45
    • (1998) Sens. Actuators B: Chemical , vol.49 , pp. 40-45
    • Gonzalez, C.1    Collins, S.D.2    Smith, R.L.3
  • 59
    • 0000266265 scopus 로고    scopus 로고
    • Using neutral metastable argon atoms and contamination lithography to form nanostructures in silicon, silicon dioxide, and gold
    • Johnson KS et al (1996) Using neutral metastable argon atoms and contamination lithography to form nanostructures in silicon, silicon dioxide, and gold. Appl Phys Lett 69: 2773-2775
    • (1996) Appl Phys Lett , vol.69 , pp. 2773-2775
    • Johnson, K.S.1
  • 60
    • 0031221057 scopus 로고    scopus 로고
    • Su-8: A low-cost negative resist for mems
    • Lorenz H et al (1997) SU-8: a low-cost negative resist for MEMS. J Micromech Microeng 7:121
    • (1997) J Micromech Microeng , vol.7 , pp. 121
    • Lorenz, H.1
  • 62
    • 0030100650 scopus 로고    scopus 로고
    • Silicon fusion bonding and deep reactive ion etching; A new technology for microstructures
    • Klaassen EH et al. (1996) Silicon fusion bonding and deep reactive ion etching; a new technology for microstructures. Sens. Actuators A: Physical 52:132-139
    • (1996) Sens. Actuators A: Physical , vol.52 , pp. 132-139
    • Klaassen, E.H.1
  • 63
    • 0029514572 scopus 로고
    • A novel etchdiffusion process for fabricating high aspect ratio Si microstructures
    • Transducers '95 Stockholm, Sweden
    • Juan WH, Pang SW (1995) A novel etchdiffusion process for fabricating high aspect ratio Si microstructures. In: Proc. 8th Int. Conf. Solid-State Sensors and Actuators (Transducers '95), Stockholm, Sweden, pp 560-563
    • (1995) Proc. 8th Int. Conf. Solid-State Sensors and Actuators , pp. 560-563
    • Juan, W.H.1    Pang, S.W.2
  • 65
    • 34248552006 scopus 로고    scopus 로고
    • High resolution soft lithography: Enabling materials for nanotechnologies
    • Rolland JP et al (2004) High Resolution Soft Lithography: Enabling Materials for Nanotechnologies. Angewandte Chemie 116:5920-5923
    • (2004) Angewandte Chemie , vol.116 , pp. 5920-5923
    • Rolland, J.P.1
  • 67
    • 79952312661 scopus 로고    scopus 로고
    • Micro fluidics for medical diagnostics and biosensors
    • Rivet C et al (2010) Micro fluidics for medical diagnostics and biosensors. Chem Engine Sci 66:1490-1507
    • (2010) Chem Engine Sci , vol.66 , pp. 1490-1507
    • Rivet, C.1
  • 70
    • 0042040751 scopus 로고    scopus 로고
    • Co2-laser micromachining and back-end processing for rapid production of pmma-based micro fluidic systems
    • Klank H, Kutter JP, Geschke O (2002) CO2-laser micromachining and back-end processing for rapid production of PMMA-based micro fluidic systems. Lab Chip 2:242-246
    • (2002) Lab Chip , vol.2 , pp. 242-246
    • Klank, H.1    Kutter, J.P.2    Geschke, O.3
  • 71
    • 37549023085 scopus 로고    scopus 로고
    • Polymer microfabrication technologies for micro fluidic systems
    • Becker H, Gärtner C (2008) Polymer microfabrication technologies for micro fluidic systems. Anal Bioanal Chem 390:89-111
    • (2008) Anal Bioanal Chem , vol.390 , pp. 89-111
    • Becker, H.1    Gärtner, C.2
  • 72
    • 58149378331 scopus 로고    scopus 로고
    • Three-dimensional micro fluidic devices fabricated in layered paper and tape
    • Martinez AW, Phillips ST, Whitesides GM (2008) Three-dimensional micro fluidic devices fabricated in layered paper and tape. Proc Natl Acad Sci 105:19606-19611
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 19606-19611
    • Martinez, A.W.1    Phillips, S.T.2    Whitesides, G.M.3
  • 73
    • 75749113741 scopus 로고    scopus 로고
    • Diagnostics for the developing world: Micro fluidic paper-based analytical devices
    • Martinez AW et al (2009) Diagnostics for the developing world: micro fluidic paper-based analytical devices. Anal Chem 82:3-10
    • (2009) Anal Chem , vol.82 , pp. 3-10
    • Martinez, A.W.1
  • 74
    • 32444435013 scopus 로고    scopus 로고
    • Thermoplastic micro fluidic device for on-chip puri fication of nucleic acids for disposable diagnostics
    • Bhattacharyya A, Klapperich CM (2006) Thermoplastic micro fluidic device for on-chip puri fication of nucleic acids for disposable diagnostics. Anal Chem 78:788-792
    • (2006) Anal Chem , vol.78 , pp. 788-792
    • Bhattacharyya, A.1    Klapperich, C.M.2
  • 75
    • 33747086959 scopus 로고    scopus 로고
    • Micro fluidic diagnostic technologies for global public health
    • Yager P et al (2006) Micro fluidic diagnostic technologies for global public health. Nature 442:412-418
    • (2006) Nature , vol.442 , pp. 412-418
    • Yager, P.1
  • 76
    • 24944498780 scopus 로고    scopus 로고
    • Micro fluidics: Fluid physics at the nanoliter scale
    • Squires TM, Quake SR (2005) Micro fluidics: Fluid physics at the nanoliter scale. Rev Mod Phys 77:977
    • (2005) Rev Mod Phys , vol.77 , pp. 977
    • Squires, T.M.1    Quake, S.R.2
  • 77
    • 33747133014 scopus 로고    scopus 로고
    • Developing opto fluidic technology through the fusion of micro fluidics and optics
    • Psaltis D, Quake SR, Yang C (2006) Developing opto fluidic technology through the fusion of micro fluidics and optics. Nature 442:381-386
    • (2006) Nature , vol.442 , pp. 381-386
    • Psaltis, D.1    Quake, S.R.2    Yang, C.3
  • 78
    • 33747090983 scopus 로고    scopus 로고
    • Control and detection of chemical reactions in micro fluidic systems
    • Demello AJ (2006) Control and detection of chemical reactions in micro fluidic systems. Nature 442:394-402
    • (2006) Nature , vol.442 , pp. 394-402
    • Demello, A.J.1
  • 79
    • 56549083018 scopus 로고    scopus 로고
    • Innovations in optical micro fluidic technologies for point-ofcare diagnostics
    • Myers FB, Lee LP (2008) Innovations in optical micro fluidic technologies for point-ofcare diagnostics. Lab Chip 8:2015-2031
    • (2008) Lab Chip , vol.8 , pp. 2015-2031
    • Myers, F.B.1    Lee, L.P.2
  • 80
    • 34848902629 scopus 로고    scopus 로고
    • Grand challenges in global health: The ethical, social and cultural program
    • Singer PA et al (2007) Grand challenges in global health: the ethical, social and cultural program. PLoS Med 4:e265
    • (2007) PLoS Med , vol.4
    • Singer, P.A.1
  • 81
    • 33845910922 scopus 로고    scopus 로고
    • Lab-on-Achip devices for global health: Past studies and future opportunities
    • Chin CD, Linder V, Sia SK (2007) Lab-on-Achip devices for global health: past studies and future opportunities. Lab Chip 7:41-57
    • (2007) Lab Chip , vol.7 , pp. 41-57
    • Chin, C.D.1    Linder, V.2    Sia, S.K.3
  • 82
    • 79952193925 scopus 로고    scopus 로고
    • World Health Organization World Health Organization, Geneva
    • World Health Organization (2010) World malaria report: 2010. World Health Organization, Geneva
    • (2010) World Malaria Report , pp. 2010
  • 83
    • 77249123257 scopus 로고    scopus 로고
    • 2010/2011 Tuberculosis Global Facts, Geneva
    • World Health Organization (2010) 2010/2011 Tuberculosis Global Facts, Geneva.
    • (2010) World Health Organization
  • 84
    • 0003614725 scopus 로고    scopus 로고
    • World Health Organization (2009-2010) Situation updates-Pandemic (H1N1) 2009 World Health Organization, Geneva
    • United Nations (2000) United Nations Millennium Declaration . 85. World Health Organization. (2009-2010) Situation updates-Pandemic (H1N1) 2009, World Health Organization, Geneva.
    • (2000) United Nations Millennium Declaration , vol.85
    • Nations, U.1
  • 85
    • 73949098473 scopus 로고    scopus 로고
    • Estimates of the prevalence of pandemic (h1n1) 2009, united states
    • April-July 2009
    • Reed C et al (2009) Estimates of the prevalence of pandemic (H1N1) 2009, United States, April-July 2009. Emerg Infect Dis 15: 2004-2007
    • (2009) Emerg Infect Dis , vol.15 , pp. 2004-2007
    • Reed, C.1
  • 86
    • 0032745921 scopus 로고    scopus 로고
    • Biosensors for detection of pathogenic bacteria
    • Ivnitski D et al (1999) Biosensors for detection of pathogenic bacteria. Biosens Bioelectron 14:599-624
    • (1999) Biosens Bioelectron , vol.14 , pp. 599-624
    • Ivnitski, D.1
  • 87
    • 79958152802 scopus 로고    scopus 로고
    • Sample to answer: A fully integrated nucleic acid identi fication system for bacteria monitoring
    • Becker H, Wang W (eds)
    • Kim J et al. (2010) Sample to answer: a fully integrated nucleic acid identi fication system for bacteria monitoring. In: Becker H, Wang W (eds) Proc. SPIE, vol 7593, pp 75930S
    • (2010) Proc. SPIE , vol.7593
    • Kim, J.1
  • 88
    • 76949097724 scopus 로고    scopus 로고
    • Micro fluidic sample preparation: Cell lysis and nucleic acidpuri fication
    • Kim J et al (2009) Micro fluidic sample preparation: cell lysis and nucleic acidpuri fication. Integr Biol 1:574-586
    • (2009) Integr Biol , vol.1 , pp. 574-586
    • Kim, J.1
  • 90
    • 74449087608 scopus 로고    scopus 로고
    • An overview of foodborne pathogen detection in the perspective of biosensors
    • Velusamy V et al (2010) An overview of foodborne pathogen detection: In the perspective of biosensors. Biotechnol Adv 28:232-254
    • (2010) Biotechnol Adv , vol.28 , pp. 232-254
    • Velusamy, V.1
  • 91
    • 33846448162 scopus 로고    scopus 로고
    • Pathogen detection: A perspective of traditional methods and biosensors
    • Lazcka O, Campo F, Munoz FX (2007) Pathogen detection: A perspective of traditional methods and biosensors. Biosens Bioelectron 22:1205-1217
    • (2007) Biosens Bioelectron , vol.22 , pp. 1205-1217
    • Lazcka, O.1    Campo, F.2    Munoz, F.X.3
  • 92
    • 33645219296 scopus 로고    scopus 로고
    • Miniaturized immunoassay micro fluidic system with electrokinetic control
    • Xiang Q et al (2006) Miniaturized immunoassay micro fluidic system with electrokinetic control. Biosens Bioelectron 21(10): 2006-2009
    • (2006) Biosens Bioelectron , vol.21 , Issue.10 , pp. 2006-2009
    • Xiang, Q.1
  • 93
    • 36749100909 scopus 로고    scopus 로고
    • Multiplexed high-throughput electrokinetically-controlled immunoassay for the detection of speci ficbacterial antibodies in human serum
    • Gao Y et al (2008) Multiplexed high-throughput electrokinetically- controlled immunoassay for the detection of speci ficbacterial antibodies in human serum. Anal Chim Acta 606:98-107
    • (2008) Anal Chim Acta , vol.606 , pp. 98-107
    • Gao, Y.1
  • 94
    • 56549118219 scopus 로고    scopus 로고
    • An integrated micro fluidic platform for sensitive and rapid detection of biological toxins
    • Meagher RJ et al (2008) An integrated micro fluidic platform for sensitive and rapid detection of biological toxins. Lab Chip 8:2046-2053
    • (2008) Lab Chip , vol.8 , pp. 2046-2053
    • Meagher, R.J.1
  • 95
    • 70849103161 scopus 로고    scopus 로고
    • An overview of recent strategies in pathogen sensing
    • JinSeok H, Hua SZ (2009) An overview of recent strategies in pathogen sensing. Sensors 9:4483-4502
    • (2009) Sensors , vol.9 , pp. 4483-4502
    • Jinseok, H.1    Hua, S.Z.2
  • 96
    • 34548639001 scopus 로고    scopus 로고
    • On-chip micro fluidic biosensor for bacterial detection and identi fication
    • Boehm DA, Gottlieb PA, Hua SZ (2007) On-chip micro fluidic biosensor for bacterial detection and identi fication. Sensors Actuators B: Chemical 126:508-514
    • (2007) Sensors Actuators B: Chemical , vol.126 , pp. 508-514
    • Boehm, D.A.1    Gottlieb, P.A.2    Hua, S.Z.3
  • 97
    • 32344432775 scopus 로고    scopus 로고
    • Use of electrochemical DNA biosensors for rapid molecular identi fication of uropathogens in clinical urine specimens
    • Liao JC et al (2006) Use of electrochemical DNA biosensors for rapid molecular identi fication of uropathogens in clinical urine specimens. J Clin Microbiol 44:561-570
    • (2006) J Clin Microbiol , vol.44 , pp. 561-570
    • Liao, J.C.1
  • 98
    • 56549086851 scopus 로고    scopus 로고
    • Enabling a micro fluidic immunoassay for the developing world by integration of on-card dry reagent storage
    • Stevens DY et al (2008) Enabling a micro fluidic immunoassay for the developing world by integration of on-card dry reagent storage. Lab Chip 8:2038-2045
    • (2008) Lab Chip , vol.8 , pp. 2038-2045
    • Stevens, D.Y.1
  • 99
    • 57849122470 scopus 로고    scopus 로고
    • Micro-And nanotechnology for viral detection
    • Cheng X, Chen G, Rodriguez WR (2009) Micro-And nanotechnology for viral detection. Anal Bioanal Chem 393:487-501
    • (2009) Anal Bioanal Chem , vol.393 , pp. 487-501
    • Cheng, X.1    Chen, G.2    Rodriguez, W.R.3
  • 101
    • 78650407591 scopus 로고    scopus 로고
    • Tackling HIV through robust diagnostics in the developing world: Current status and future opportunities
    • Desai D, Wu G, Zaman MH (2010) Tackling HIV through robust diagnostics in the developing world: current status and future opportunities. Lab Chip 11(2):194-211
    • (2010) Lab Chip , vol.11 , Issue.2 , pp. 194-211
    • Desai, D.1    Wu, G.2    Zaman, M.H.3
  • 102
    • 76849096270 scopus 로고    scopus 로고
    • Nano/micro fluidics for diagnosis of infectious diseases in developing countries
    • Lee WG et al (2010) Nano/Micro fluidics for diagnosis of infectious diseases in developing countries. Adv Drug Deliv Rev 62:449-457
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 449-457
    • Lee, W.G.1
  • 103
    • 56549102421 scopus 로고    scopus 로고
    • A polymer lab-on-A-chip for reverse transcription (RT)-PCR based point-of-care clinical diagnostics
    • Lee SH et al (2008) A polymer lab-on-A-chip for reverse transcription (RT)-PCR based point-of-care clinical diagnostics. Lab Chip 8:2121-2127
    • (2008) Lab Chip , vol.8 , pp. 2121-2127
    • Lee, S.H.1
  • 104
    • 65649083715 scopus 로고    scopus 로고
    • Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics
    • Cheng X et al (2009) Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. Lab Chip 9:1357-1364
    • (2009) Lab Chip , vol.9 , pp. 1357-1364
    • Cheng, X.1
  • 105
    • 33846932778 scopus 로고    scopus 로고
    • A micro fluidic device for practical label-free CD4+ T cell counting of HIV-infected subjects
    • Cheng X et al (2007) A micro fluidic device for practical label-free CD4+ T cell counting of HIV-infected subjects. Lab Chip 7:170-178
    • (2007) Lab Chip , vol.7 , pp. 170-178
    • Cheng, X.1
  • 106
    • 34347338697 scopus 로고    scopus 로고
    • A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings
    • Cheng X et al (2007) A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. JAIDS J Acquired Immune De fi ciency Syndrom 45:257-261
    • (2007) JAIDS J Acquired Immune de Fi Ciency Syndrom , vol.45 , pp. 257-261
    • Cheng, X.1
  • 107
    • 67349097407 scopus 로고    scopus 로고
    • Integrating micro fluidics and lensless imaging for point-of-care testing
    • Moon SJ et al (2009) Integrating micro fluidics and lensless imaging for point-of-care testing. Biosens Bioelectron 24:3208-3214
    • (2009) Biosens Bioelectron , vol.24 , pp. 3208-3214
    • Moon, S.J.1
  • 108
    • 34249787875 scopus 로고    scopus 로고
    • Cell detection and counting through cell lysate impedance spectroscopy in micro fluidic devices
    • Cheng X et al (2007) Cell detection and counting through cell lysate impedance spectroscopy in micro fluidic devices. Lab Chip 7:746-755
    • (2007) Lab Chip , vol.7 , pp. 746-755
    • Cheng, X.1
  • 109
    • 77954810748 scopus 로고    scopus 로고
    • Label free detection of cd4+ and cd8+ t cells using the opto fluidic ring resonator
    • Gohring JT, Fan X (2010) Label Free Detection of CD4+ and CD8+ T Cells Using the Opto fluidic Ring Resonator. Sensors 10:5798-5808
    • (2010) Sensors , vol.10 , pp. 5798-5808
    • Gohring, J.T.1    Fan, X.2
  • 110
    • 79955960929 scopus 로고    scopus 로고
    • An integrated micro fluidic system for counting of CD4+/CD8+ T lymphocytes
    • Wang JH et al (2011) An integrated micro fluidic system for counting of CD4+/CD8+ T lymphocytes. Micro fluid Nano fluid 10:531-541
    • (2011) Micro Fluid Nano Fluid , vol.10 , pp. 531-541
    • Wang, J.H.1
  • 111
    • 79955161176 scopus 로고    scopus 로고
    • Rapid detection for primary screening of in fluenza a virus: Micro fluidic rt-pcr chip and electrochemical DNA sensor
    • Yamanaka K et al (2011) Rapid detection for primary screening of in fluenza A virus: micro fluidic RT-PCR chip and electrochemical DNA sensor. Analyst 136(10):2064-2068
    • (2011) Analyst , vol.136 , Issue.10 , pp. 2064-2068
    • Yamanaka, K.1
  • 112
    • 67649297821 scopus 로고    scopus 로고
    • Emergence and pandemic potential of swineorigin H1N1 in fluenza virus
    • Neumann G, Noda T, Kawaoka Y (2009) Emergence and pandemic potential of swineorigin H1N1 in fluenza virus. Nature 459:931-939
    • (2009) Nature , vol.459 , pp. 931-939
    • Neumann, G.1    Noda, T.2    Kawaoka, Y.3
  • 113
    • 79955484535 scopus 로고    scopus 로고
    • Rapid detection of in fluenza A virus infection utilizing an immunomagnetic bead-based micro fluidic system
    • Lien KY et al (2011) Rapid detection of in fluenza A virus infection utilizing an immunomagnetic bead-based micro fluidic system. Biosens Bioelectron 26:3900-3907
    • (2011) Biosens Bioelectron , vol.26 , pp. 3900-3907
    • Lien, K.Y.1
  • 114
    • 79958785745 scopus 로고    scopus 로고
    • Genetic analysis of h1n1 in fluenza virus from throat swab samples in a micro fluidic System for Pointof-Care Diagnostics
    • Ferguson BS et al (2011) Genetic Analysis of H1N1 In fluenza Virus from Throat Swab Samples in a Micro fluidic System for Pointof-Care Diagnostics. J Am Chem Soc 133(23):9129-9135
    • (2011) J Am Chem Soc , vol.133 , Issue.23 , pp. 9129-9135
    • Ferguson, B.S.1
  • 115
    • 36549008526 scopus 로고    scopus 로고
    • Virus analysis by electrophoresis on a micro fluidic chip
    • Weiss VU et al (2007) Virus analysis by electrophoresis on a micro fluidic chip. J Chromatogr B 860:173-179
    • (2007) J Chromatogr B , vol.860 , pp. 173-179
    • Weiss, V.U.1
  • 116
    • 40049105266 scopus 로고    scopus 로고
    • Opto-fluidic micro-ring resonator for sensitive label-free viral detection
    • Zhu H et al (2008) Opto-fluidic micro-ring resonator for sensitive label-free viral detection. Analyst 133:356-360
    • (2008) Analyst , vol.133 , pp. 356-360
    • Zhu, H.1
  • 117
    • 58649119277 scopus 로고    scopus 로고
    • Enhanced on-chip sers based biomolecular detection using electrokinetically active microwells
    • Huh YS et al (2008) Enhanced on-chip SERS based biomolecular detection using electrokinetically active microwells. Lab Chip 9:433-439
    • (2008) Lab Chip , vol.9 , pp. 433-439
    • Huh, Y.S.1
  • 118
    • 79958173601 scopus 로고    scopus 로고
    • A suction-type micro fluidic immunosensing chip for rapid detection of the dengue virus
    • Weng CH et al (2011) A suction-type micro fluidic immunosensing chip for rapid detection of the dengue virus. Biomed Microdevices 13(3):585-595
    • (2011) Biomed Microdevices , vol.13 , Issue.3 , pp. 585-595
    • Weng, C.H.1
  • 119
    • 66149108280 scopus 로고    scopus 로고
    • A fully automated immunoassay from whole blood on a disc
    • Lee BS et al (2009) A fully automated immunoassay from whole blood on a disc. Lab Chip 9:1548-1555
    • (2009) Lab Chip , vol.9 , pp. 1548-1555
    • Lee, B.S.1
  • 120
    • 64549164505 scopus 로고    scopus 로고
    • Micro fluidic immunosensor for rapid and sensitive detection of bovine viral diarrhea virus
    • Heinze BC et al (2009) Micro fluidic immunosensor for rapid and sensitive detection of bovine viral diarrhea virus. Sensors and Actuators B: Chemical 138:491-496
    • (2009) Sensors and Actuators B: Chemical , vol.138 , pp. 491-496
    • Heinze, B.C.1
  • 121
    • 78650602536 scopus 로고    scopus 로고
    • An integrated micro fluidic loop-mediated-isothermal-Ampli fication system for rapid sample pre-treatment and detection of viruses
    • Wang C et al (2011) An integrated micro fluidic loop-mediated-isothermal- Ampli fication system for rapid sample pre-treatment and detection of viruses. Biosens Bioelectron 26(5):2045-2052
    • (2011) Biosens Bioelectron , vol.26 , Issue.5 , pp. 2045-2052
    • Wang, C.1
  • 123
    • 77953674451 scopus 로고    scopus 로고
    • Nanotechnology for early cancer detection
    • Choi YE, Kwak JW, Park JW (2010) Nanotechnology for early cancer detection. Sensors 10:428-455
    • (2010) Sensors , vol.10 , pp. 428-455
    • Choi, Y.E.1    Kwak, J.W.2    Park, J.W.3
  • 124
    • 33748561818 scopus 로고    scopus 로고
    • Biomarkers in cancer screening, research and detection: Present and future: A review
    • Kumar S, Mohan A, Guleria R (2006) Biomarkers in cancer screening, research and detection: present and future: a review. Biomarkers 11:385-405
    • (2006) Biomarkers , vol.11 , pp. 385-405
    • Kumar, S.1    Mohan, A.2    Guleria, R.3
  • 125
    • 41649100689 scopus 로고    scopus 로고
    • Mining the plasma proteome for cancer biomarkers
    • Hanash SM, Pitteri SJ, Faca VM (2008) Mining the plasma proteome for cancer biomarkers. Nature 452:571-579
    • (2008) Nature , vol.452 , pp. 571-579
    • Hanash, S.M.1    Pitteri, S.J.2    Faca, V.M.3
  • 126
    • 50849089350 scopus 로고    scopus 로고
    • Antibody fragments as probe in biosensor development
    • Saerens D et al (2008) Antibody fragments as probe in biosensor development. Sensors 8:4669-4686
    • (2008) Sensors , vol.8 , pp. 4669-4686
    • Saerens, D.1
  • 127
    • 33747064917 scopus 로고    scopus 로고
    • How does DNA sequence motif discovery work?
    • D'Haeseleer P (2006) How does DNA sequence motif discovery work? Nat Biotechnol 24:959-961
    • (2006) Nat Biotechnol , vol.24 , pp. 959-961
    • D'haeseleer, P.1
  • 128
    • 65949096925 scopus 로고    scopus 로고
    • Biomarkers for prostate cancer
    • Makarov DV et al (2009) Biomarkers for prostate cancer. Annu Rev Med 60:139-151
    • (2009) Annu Rev Med , vol.60 , pp. 139-151
    • Makarov, D.V.1
  • 129
    • 33645232520 scopus 로고    scopus 로고
    • Electrochemical biosensors: Towards point-of-care cancer diagnostics
    • Wang J (2006) Electrochemical biosensors: towards point-of-care cancer diagnostics. Biosens Bioelectron 21:1887-1892
    • (2006) Biosens Bioelectron , vol.21 , pp. 1887-1892
    • Wang, J.1
  • 130
    • 56349111425 scopus 로고    scopus 로고
    • Toward a simpli fied micro fluidic device for ultra-fast genetic analysis with sample-in/answer-out capability: Application to t-cell lymphoma diagnosis
    • Legendre LA et al (2008) Toward a Simpli fied Micro fluidic Device for Ultra-fast Genetic Analysis with Sample-In/Answer-Out Capability: Application to T-Cell Lymphoma Diagnosis. J Assoc Laboratory Automation 13:351-360
    • (2008) J Assoc Laboratory Automation , vol.13 , pp. 351-360
    • Legendre, L.A.1
  • 131
    • 58349084261 scopus 로고    scopus 로고
    • A micro fluidic device for multiplexed protein detection in nano-liter volumes
    • Diercks AH et al (2009) A micro fluidic device for multiplexed protein detection in nano-liter volumes. Anal Biochem 386:30-35
    • (2009) Anal Biochem , vol.386 , pp. 30-35
    • Diercks, A.H.1
  • 132
    • 73649138235 scopus 로고    scopus 로고
    • Internally calibrated quanti fication of VEGF in human plasma by fluorescence immunoassays in disposable elastomeric micro fluidic devices
    • Lin DH et al (2010) Internally calibrated quanti fication of VEGF in human plasma by fluorescence immunoassays in disposable elastomeric micro fluidic devices. J Chromatogr B 878:258-263
    • (2010) J Chromatogr B , vol.878 , pp. 258-263
    • Lin, D.H.1
  • 133
    • 49149122934 scopus 로고    scopus 로고
    • Chip-NMR biosensor for detection and molecular analysis of cells
    • Lee H et al (2008) Chip-NMR biosensor for detection and molecular analysis of cells. Nat Med 14:869-874
    • (2008) Nat Med , vol.14 , pp. 869-874
    • Lee, H.1
  • 134
    • 84892927006 scopus 로고    scopus 로고
    • Micro fluidic bioanalytical platforms with mass spectrometry detection for biomarker discovery and screening
    • Severine le Gac, Albert van den Berg (eds) Royal Society of Chemistry, 1st ed.
    • Lazar IM (2008) Micro fluidic bioanalytical platforms with mass spectrometry detection for biomarker discovery and screening In: Severine le Gac, Albert van den Berg (eds) Miniaturization and Mass Spectrometry, Royal Society of Chemistry, 1st ed., pp 151-172
    • (2008) Miniaturization and Mass Spectrometry , pp. 151-172
    • Lazar, I.M.1
  • 135
    • 77956925683 scopus 로고    scopus 로고
    • A micro fluidic system with surface modi fied piezoelectric sensor for trapping and detection of cancer cells
    • Zhang K et al (2010) A micro fluidic system with surface modi fied piezoelectric sensor for trapping and detection of cancer cells. Biosens Bioelectron 26(2):935-939
    • (2010) Biosens Bioelectron , vol.26 , Issue.2 , pp. 935-939
    • Zhang, K.1
  • 136
    • 77749324138 scopus 로고    scopus 로고
    • Label-free biomarker sensing in undiluted serum with suspended microchannel resonators
    • von Muhlen MG et al (2010) Label-free biomarker sensing in undiluted serum with suspended microchannel resonators. Anal Chem 82:1905-1910
    • (2010) Anal Chem , vol.82 , pp. 1905-1910
    • Von Muhlen, M.G.1
  • 137
    • 78650701076 scopus 로고    scopus 로고
    • A new electrochemical multiplexed assay for psa cancer marker detection
    • Zani A et al (2011) A New Electrochemical Multiplexed Assay for PSA Cancer Marker Detection. Electroanalysis 23:91-99
    • (2011) Electroanalysis , vol.23 , pp. 91-99
    • Zani, A.1
  • 138
    • 79551621190 scopus 로고    scopus 로고
    • Integrated micro fluidic platform for the electrochemical detection of breast cancer markers in patient serum samples
    • Fragoso A et al (2010) Integrated micro fluidic platform for the electrochemical detection of breast cancer markers in patient serum samples. Lab Chip 11(4):625-631
    • (2010) Lab Chip , vol.11 , Issue.4 , pp. 625-631
    • Fragoso, A.1
  • 139
    • 79953772945 scopus 로고    scopus 로고
    • Automated microsystem for electrochemical detection of cancer markers
    • Kellner C et al (2011) Automated microsystem for electrochemical detection of cancer markers. Electrophoresis 32:926-930
    • (2011) Electrophoresis , vol.32 , pp. 926-930
    • Kellner, C.1
  • 140
    • 79960145526 scopus 로고    scopus 로고
    • Cost estimation of cardiovascular disease events in the us
    • O'Sullivan A et al (2011) Cost Estimation of Cardiovascular Disease Events in the US. Pharmacoeconomics 29(8):693-704
    • (2011) Pharmacoeconomics , vol.29 , Issue.8 , pp. 693-704
    • O'sullivan, A.1
  • 141
    • 63649154820 scopus 로고    scopus 로고
    • Cardiac biomarkers and the case for point-of-care testing
    • McDonnell B et al (2009) Cardiac biomarkers and the case for point-of-care testing. Clin Biochem 42:549-561
    • (2009) Clin Biochem , vol.42 , pp. 549-561
    • McDonnell, B.1
  • 142
    • 79551623770 scopus 로고    scopus 로고
    • Lab-on-A-chip based immunosensor principles and technologies for the detection of cardiac biomarkers: A review
    • Mohammed MI, Desmulliez MPY (2010) Lab-on-A-chip based immunosensor principles and technologies for the detection of cardiac biomarkers: a review. Lab Chip 11(4):569-595
    • (2010) Lab Chip , vol.11 , Issue.4 , pp. 569-595
    • Mohammed, M.I.1    Mpy, D.2
  • 143
    • 3142608724 scopus 로고    scopus 로고
    • Evaluation of a pointof-care assay for cardiac markers for patients suspected of acute myocardial infarction
    • Wu AHB et al (2004) Evaluation of a pointof-care assay for cardiac markers for patients suspected of acute myocardial infarction. Clin Chim Acta 346:211-219
    • (2004) Clin Chim Acta , vol.346 , pp. 211-219
    • Ahb, W.1
  • 144
    • 32044455998 scopus 로고    scopus 로고
    • Risk strati fication of chest pain patients by pointof-care cardiac troponin T and myoglobin measured in the emergency department
    • Ordonez-Llanos J et al (2006) Risk strati fication of chest pain patients by pointof-care cardiac troponin T and myoglobin measured in the emergency department. Clin Chim Acta 365:93-97
    • (2006) Clin Chim Acta , vol.365 , pp. 93-97
    • Ordonez-Llanos, J.1
  • 145
    • 1242317141 scopus 로고    scopus 로고
    • A rapid troponin i assay is not optimal for determination of troponin status and prediction of subsequent cardiac events at suspicion of unstable coronary syndromes
    • James SK et al (2004) A rapid troponin I assay is not optimal for determination of troponin status and prediction of subsequent cardiac events at suspicion of unstable coronary syndromes. Int J Cardiol 93:113-120
    • (2004) Int J Cardiol , vol.93 , pp. 113-120
    • James, S.K.1
  • 146
    • 34248139791 scopus 로고    scopus 로고
    • Lack of concordance between a rapid bedside and conventional laboratory method of cardiac troponin testing: Impact on risk strati fication of patients suspected of acute coronary syndrome
    • Cramer GE et al (2007) Lack of concordance between a rapid bedside and conventional laboratory method of cardiac troponin testing: impact on risk strati fication of patients suspected of acute coronary syndrome. Clin Chim Acta 381:164-166
    • (2007) Clin Chim Acta , vol.381 , pp. 164-166
    • Cramer, G.E.1
  • 147
    • 46149100744 scopus 로고    scopus 로고
    • Silane-dextran chemistry on lateral flow polymer chips for immunoassays
    • Jönsson C et al (2008) Silane-dextran chemistry on lateral flow polymer chips for immunoassays. Lab Chip 8:1191-1197
    • (2008) Lab Chip , vol.8 , pp. 1191-1197
    • Jönsson, C.1
  • 148
    • 72849110297 scopus 로고    scopus 로고
    • Toward one-step point-of-care immunodiagnostics using capillary-driven micro fluidics and PDMS substrates
    • Gervais L, Delamarche E (2009) Toward one-step point-of-care immunodiagnostics using capillary-driven micro fluidics and PDMS substrates. Lab Chip 9:3330-3337
    • (2009) Lab Chip , vol.9 , pp. 3330-3337
    • Gervais, L.1    Delamarche, E.2
  • 149
    • 84934435090 scopus 로고    scopus 로고
    • Highly sensitive rapid, reliable, and automatic cardiovascular disease diagnosis with nanoparticle fluorescence enhancer and MEMS
    • Hong B et al (2008) Highly sensitive rapid, reliable, and automatic cardiovascular disease diagnosis with nanoparticle fluorescence enhancer and MEMS. Adv Exp Med Biol 614:265-273
    • (2008) Adv Exp Med Biol , vol.614 , pp. 265-273
    • Hong, B.1
  • 150
    • 34147141958 scopus 로고    scopus 로고
    • Design and testing of a disposable micro fluidic chemiluminescent immunoassay for disease biomarkers in human serum samples
    • Bhattacharyya A, Klapperich CM (2007) Design and testing of a disposable micro fluidic chemiluminescent immunoassay for disease biomarkers in human serum samples. Biomed Microdevices 9:245-251
    • (2007) Biomed Microdevices , vol.9 , pp. 245-251
    • Bhattacharyya, A.1    Klapperich, C.M.2
  • 151
    • 57849123141 scopus 로고    scopus 로고
    • Chemiluminometric enzyme-linked immunosorbent assays (ELISA)-on-A-chip biosensor based on crossflow chromatography
    • Cho IH et al (2009) Chemiluminometric enzyme-linked immunosorbent assays (ELISA)-on-A-chip biosensor based on crossflow chromatography. Anal Chim Acta 632:247-255
    • (2009) Anal Chim Acta , vol.632 , pp. 247-255
    • Cho, I.H.1
  • 152
    • 59949085245 scopus 로고    scopus 로고
    • Rapid analysis of alphafetoprotein by chemiluminescence micro fluidic immunoassay system based on super-paramagnetic microbeads
    • Huang H et al (2009) Rapid analysis of alphafetoprotein by chemiluminescence micro fluidic immunoassay system based on super-paramagnetic microbeads. Biomed Microdevices 11:213-216
    • (2009) Biomed Microdevices , vol.11 , pp. 213-216
    • Huang, H.1
  • 153
    • 56549119892 scopus 로고    scopus 로고
    • Development of a digital micro fluidic platform for point of care testing
    • Sista R et al (2008) Development of a digital micro fluidic platform for point of care testing. Lab Chip 8:2091-2104
    • (2008) Lab Chip , vol.8 , pp. 2091-2104
    • Sista, R.1
  • 154
    • 33746801083 scopus 로고    scopus 로고
    • On-chip enzyme immunoassay of a cardiac marker using a micro fluidic device combined with a portable surface plasmon resonance system
    • Kurita R et al (2006) On-chip enzyme immunoassay of a cardiac marker using a micro fluidic device combined with a portable surface plasmon resonance system. Anal Chem 78:5525-5531
    • (2006) Anal Chem , vol.78 , pp. 5525-5531
    • Kurita, R.1
  • 156
    • 58349095343 scopus 로고    scopus 로고
    • Cardiac point of care testing: A focused review of current national academy of clinical Biochemistry guidelines and measurement platforms
    • Christenson RH, Azzazy HME (2009) Cardiac point of care testing: a focused review of current National Academy of Clinical Biochemistry guidelines and measurement platforms. Clin Biochem 42:150-157
    • (2009) Clin Biochem , vol.42 , pp. 150-157
    • Christenson, R.H.1    Hme, A.2
  • 157
    • 41549139592 scopus 로고    scopus 로고
    • Development of a myoglobin impedimetric immunosensor based on mixed self-Assembled monolayer onto gold
    • Billah M, Hays HCW, Millner PA (2008) Development of a myoglobin impedimetric immunosensor based on mixed self-Assembled monolayer onto gold. Microchimica Acta 160:447-454
    • (2008) Microchimica Acta , vol.160 , pp. 447-454
    • Billah, M.1    Hcw, H.2    Millner, P.A.3
  • 158
    • 78149489834 scopus 로고    scopus 로고
    • Electrochemical immunosensor for simultaneous detection of dual cardiac markers Based on a poly (dimethylsiloxane)-gold nanoparticles composite micro fluidic chip: A proof of Principle
    • Zhou F et al (2010) Electrochemical Immunosensor for Simultaneous Detection of Dual Cardiac Markers Based on a Poly (Dimethylsiloxane)-Gold Nanoparticles Composite Micro fluidic Chip: A Proof of Principle. Clin Chem 56:1701-1707
    • (2010) Clin Chem , vol.56 , pp. 1701-1707
    • Zhou, F.1
  • 159
    • 41449091313 scopus 로고    scopus 로고
    • Electrochemical impedance immunosensor based on three-dimensionally ordered macroporous gold fi lm
    • Chen X et al (2008) Electrochemical impedance immunosensor based on three-dimensionally ordered macroporous gold fi lm. Anal Chem 80:2133-2140
    • (2008) Anal Chem , vol.80 , pp. 2133-2140
    • Chen, X.1
  • 160
    • 79959523487 scopus 로고    scopus 로고
    • Detection of multiple cardiac markers with an integrated acoustic platform for cardiovascular risk assessment
    • Mitsakakis K, Gizeli E (2011) Detection of multiple cardiac markers with an integrated acoustic platform for cardiovascular risk assessment. Anal Chim Acta 699(1):1-5
    • (2011) Anal Chim Acta , vol.699 , Issue.1 , pp. 1-5
    • Mitsakakis, K.1    Gizeli, E.2
  • 161
    • 58849132813 scopus 로고    scopus 로고
    • Microand nano fluidic systems for high-throughput biological screening
    • Hong J, Edel JB, deMello AJ (2009) Microand nano fluidic systems for high-throughput biological screening. Drug Discov Today 14:134-146
    • (2009) Drug Discov Today , vol.14 , pp. 134-146
    • Hong, J.1    Edel, J.B.2    Demello, A.J.3
  • 162
    • 66449107203 scopus 로고    scopus 로고
    • Situ microarray fabrication and analysis using a micro fluidic flow cell array integrated with surface plasmon resonance microscopy
    • Liu J et al (2009) In Situ Microarray Fabrication and Analysis Using a Micro fluidic Flow Cell Array Integrated with Surface Plasmon Resonance Microscopy. Anal Chem 81:4296-4301
    • (2009) Anal Chem , vol.81 , pp. 4296-4301
    • Liu, J.1
  • 164
    • 84892928762 scopus 로고    scopus 로고
    • Accessed 12 Nov
    • The FilmArray Respiratory Panel. http://www.bio fi redx.com/FilmArray/ Respiratory Test.html. Accessed 12 Nov 2012
    • (2012) The FilmArray Respiratory Panel
  • 165
    • 84892944820 scopus 로고    scopus 로고
    • Search issued patents for "micro fluidic" in title or abstract, United States
    • -(2011) search issued patents for "micro fluidic" in title or abstract, United States Patent and Trademark office
    • (2011) Patent and Trademark Office
  • 166
    • 77952527887 scopus 로고    scopus 로고
    • Micro fluidic lab-on-A-chip platforms: Requirements, characteristics and applications
    • Mark D et al (2010) Micro fluidic lab-on-A-chip platforms: requirements, characteristics and applications. Chem Soc Rev 39:1153-1182
    • (2010) Chem Soc Rev , vol.39 , pp. 1153-1182
    • Mark, D.1
  • 167
    • 70349303095 scopus 로고    scopus 로고
    • It's the economy
    • Becker H (2009) It's the economy. Lab Chip 9:2759-2762
    • (2009) Lab Chip , vol.9 , pp. 2759-2762
    • Becker, H.1


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