Toward a Simplified Microfluidic Device for Ultra-Fast Genetic Analysis with Sample-In/Answer-Out Capability: Application to T-Cell Lymphoma Diagnosis

Journal of Laboratory Automation

Volumn 13, Issue 6, 2008, Pages 351-360

  Legendre, Lindsay A ^a,b   Morris, Carleen J ^a   Bienvenue, Joan M ^c   Barron, Annelise ^a,b   Mcclure, Rebecca ^a,b   Landers, James P ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^c Armed Forces DNA Identification Laboratory   (United States)

Author keywords

DNA; magnetic beads; Microfluidic; solid phase extraction

Indexed keywords

AMPLIFICATION; BIOASSAY; BIOCHIPS; BLOOD; CELL MEMBRANES; DNA; DNA SEQUENCES; FLUIDIC DEVICES; GENES; MICROARRAYS; NUCLEIC ACIDS; ORGANIC ACIDS;

ANALYTICAL SYSTEMS; BIO FLUIDS; BLOOD CANCERS; CELL RECEPTORS; CLINICAL DIAGNOSTICS; DNA AMPLIFICATIONS; DNA SAMPLES; ELECTROPHORETIC SEPARATIONS; GENETIC ANALYSES; HIGHLY INTEGRATED; INFECTIOUS AGENTS; MAGNETIC BEADS; MICROFLUIDIC; MICROFLUIDIC DEVICES; MONOCLONALITY; SAMPLE PREPARATIONS; SOLID-PHASE EXTRACTION; STATE OF THE ARTS; TARGET SEQUENCES; WHOLE BLOODS;

EXTRACTION;

BUFFER; DNA FRAGMENT; DOUBLE STRANDED DNA; POLYMER; REAGENT; SILICON DIOXIDE; SINGLE STRANDED DNA; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

ARTICLE; ASPIRATION BIOPSY; AUTOANALYZER; BLOOD ANALYSIS; CANCER DIAGNOSIS; CAPILLARY ELECTROPHORESIS; CELL ASSAY; CELL CLONE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DNA DETERMINATION; DNA EXTRACTION; DNA PURIFICATION; DNA SEQUENCE; ELUTION; EQUIPMENT DESIGN; FLUORESCENCE ANALYSIS; FUNCTIONAL ASSESSMENT; GENE AMPLIFICATION; GENETIC SCREENING; HIGH TEMPERATURE PROCEDURES; HUMAN; INFRARED RADIATION; LABORATORY AUTOMATION; LOW TEMPERATURE PROCEDURES; LYMPHOPROLIFERATIVE DISEASE; MICROCHIP ELECTROPHORESIS; MICROFLUIDIC ANALYSIS; MICROFLUIDICS; POINT OF CARE TESTING; POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; STANDARDIZATION; T CELL LYMPHOMA; T LYMPHOCYTE SUBPOPULATION;

EID: 56349111425     PISSN: 22110682     EISSN: 15402452     Source Type: Journal    
DOI: 10.1016/j.jala.2008.08.001     Document Type: Article

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