Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells

Food and Chemical Toxicology

Volumn 58, Issue , 2013, Pages 332-339

  Zheng, Lei ^a   Wang, Xiaoli ^a   Luo, Wenjuan ^a   Zhan, Yingzhuan ^a   Zhang, Yanmin ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Apoptosis; Brucine; Cell cycle; LoVo

Indexed keywords

BRUCINE; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN E; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL VIABILITY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; ENZYME PHOSPHORYLATION; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; STRYCHNOS NUX VOMICA; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BRUCINE; CELL CYCLE; LOVO;

APOPTOSIS; BLOTTING, WESTERN; CELL DEATH; CELL LINE; CELL LINE, TUMOR; G1 PHASE; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; STRYCHNINE;

EID: 84879288765     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.05.011     Document Type: Article

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