Pharmacokinetics of brucine after intravenous and oral administration to rats

Fitoterapia

Volumn 82, Issue 8, 2011, Pages 1302-1308

  Chen, Jun ^a   Xiao, Han Lu ^a   Hu, Rong Rong ^a   Hu, Wei ^b   Chen, Zhi Peng ^a   Cai, Hao ^a   Liu, Xiao ^a   Lu, Tu Lin ^a   Fang, Yun ^b   Cai, Bao Chang ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

Author keywords

Brucine; HPLC; Nonlinear; Pharmacokinetics; Rats

Indexed keywords

BRUCINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE COMPARISON; DRUG HALF LIFE; DRUG SCREENING; LIMIT OF QUANTITATION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INJECTIONS, INTRAVENOUS; INTESTINAL ABSORPTION; MALE; PLANT EXTRACTS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SEEDS; STRYCHNINE; STRYCHNOS;

RATTUS;

EID: 80054943968     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2011.09.004     Document Type: Article

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