A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Cervelli, Manuela ^a   Bellavia, Gabriella ^a   D'Amelio, Marcello ^b   Cavallucci, Virve ^b   Moreno, Sandra ^a   Berger, Joachim ^c   Nardacci, Roberta ^d   Marcoli, Manuela ^e   Maura, Guido ^e   Piacentini, Mauro ^d   Amendola, Roberto ^f   Cecconi, Francesco ^b   Mariottini, Paolo ^a  

^a ROMA TRE UNIVERSITY   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c MONASH UNIVERSITY   (Australia)

^d NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f ENEA C R CASACCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLPOLYAMINE OXIDASE; ACYLTRANSFERASE; FLAVOPROTEIN SPERMINE OXIDASE; KAINIC ACID; MEMBRANE PROTEIN; ORNITHINE DECARBOXYLASE; OXIDOREDUCTASE; PROTEIN IBA1; SPERMIDINE SPERMINE N1 ACYLTRANSFERASE; SPERMINE; SPERMINE OXIDASE; UNCLASSIFIED DRUG; NEUROTOXIN; POLYAMINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN INJURY; CELL LOSS; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GENE OVEREXPRESSION; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MOLECULAR PATHOLOGY; MOUSE; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYAMINE METABOLISM; PROTEIN FUNCTION; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; DBA MOUSE; DISEASE MODEL; DRUG EFFECTS; GENE DOSAGE; GENETICS; HELA CELL LINE; HUMAN; METABOLISM; NERVE CELL; PATHOLOGY; TOXICITY AND INTOXICATION;

ANIMALIA; MAMMALIA; MUS; MUS MUSCULUS;

ANIMALS; BRAIN INJURIES; DISEASE MODELS, ANIMAL; GENE DOSAGE; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, TRANSGENIC; NEURONS; NEUROTOXICITY SYNDROMES; NEUROTOXINS; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; SPERMINE;

EID: 84879238849     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064810     Document Type: Article

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