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Volumn 27, Issue 3, 2010, Pages 515-525

Polyamine catabolism is enhanced after traumatic brain injury

Author keywords

Brain injuries; Colocalization immunofluorescence; Gene expression; Polyamine back conversion; Polyamine quantification; Polyamine therapeutic potential; Spermidine=spermine N1 acetyltransferase (SSAT); Spermine oxidase (SMO); Time course

Indexed keywords

AMINOALDEHYDE; HYDROGEN PEROXIDE; NEURON SPECIFIC NUCLEAR PROTEIN; OXIDOREDUCTASE; PUTRESCINE; RNA; SPERMIDINE; SPERMINE;

EID: 77950605112     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2009.1097     Document Type: Article
Times cited : (66)

References (71)
  • 1
    • 36949028491 scopus 로고    scopus 로고
    • Epidemiology and prevention of head injuries: Literature review
    • Abelson-Mitchell, N. (2008). Epidemiology and prevention of head injuries: literature review. J. Clin. Nurs. 17, 46-57.
    • (2008) J. Clin. Nurs. , vol.17 , pp. 46-57
    • Abelson-Mitchell, N.1
  • 2
    • 0037205108 scopus 로고    scopus 로고
    • Polyamines and central nervous system injury: Spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats
    • DOI 10.1016/S0006-8993(02)02447-2, PII S0006899302024472
    • Adibhatla, R.M., Hatcher, J.F., Sailor, K., and Dempsey, R.J. (2002). Polyamines and central nervous system injury: spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats. Brain Res. 938, 81-86. (Pubitemid 34603113)
    • (2002) Brain Research , vol.938 , Issue.1-2 , pp. 81-86
    • Adibhatla, R.M.1    Hatcher, J.F.2    Sailor, K.3    Dempsey, R.J.4
  • 3
    • 0028913231 scopus 로고
    • Modulation of N-methyl-D-aspartate receptors by hydroxyl radicals in rat cortical neurons in vitro
    • Aizenman, E. (1995). Modulation of N-methyl-D-aspartate receptors by hydroxyl radicals in rat cortical neurons in vitro. Neurosci. Lett. 189, 57-59.
    • (1995) Neurosci. Lett. , vol.189 , pp. 57-59
    • Aizenman, E.1
  • 4
    • 0344392782 scopus 로고    scopus 로고
    • Ornithine decarboxylase activity in in vivo and in vitro models of cerebral ischemia
    • DOI 10.1023/A:1026123809033
    • Babu, G.N., Sailor, K.A., Beck, J., Sun, D., and Dempsey, R.J. (2003). Ornithine decarboxylase activity in in vivo and in vitro models of cerebral ischemia. Neurochem. Res. 28, 1851-1857. (Pubitemid 37444682)
    • (2003) Neurochemical Research , vol.28 , Issue.12 , pp. 1851-1857
    • Babu, G.N.1    Sailor, K.A.2    Beck, J.3    Sun, D.4    Dempsey, R.J.5
  • 6
    • 0029961987 scopus 로고    scopus 로고
    • Effect of difluoromethylornithine treatment on regional ornithine decarboxylase activity and edema formation after experimental brain injury
    • Baskaya, M.K., Rao, A.M., Puckett, L., Prasad, M.R., and Dempsey, R.J. (1996). Effect of difluoromethylornithine treatment on regional ornithine decarboxylase activity and edema formation after experimental brain injury. J. Neurotrauma 13, 85-92. (Pubitemid 26089586)
    • (1996) Journal of Neurotrauma , vol.13 , Issue.2 , pp. 85-92
    • Baskaya, M.K.1    Rao, A.M.2    Puckett, L.3    Prasad, M.R.4    Dempsey, R.J.5
  • 7
    • 9444254075 scopus 로고    scopus 로고
    • Neuroprotective effects of spermine following hypoxicischemic-induced brain damage: A mechanistic study
    • DOI 10.1096/fj.03-1203fje
    • Clarkson, A.N., Liu, H., Pearson, L., Kapoor, M., Harrison, J.C., Sammut, I.A., Jackson, D.M., and Appleton, I. (2004). Neuroprotective effects of spermine following hypoxic-ischemic-induced brain damage: a mechanistic study. FASEB J. 18, 1114-1116. (Pubitemid 39561541)
    • (2004) FASEB Journal , vol.18 , Issue.10 , pp. 1114-1116
    • Clarkson, A.N.1    Liu, H.2    Pearson, L.3    Kapoor, M.4    Harrison, J.C.5    Sammut, I.A.6    Jackson, D.M.7    Appleton, I.8
  • 8
    • 0032146787 scopus 로고    scopus 로고
    • Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
    • Conti, A.C., Raghupathi, R., Trojanowski, J.Q., and McIntosh, T.K. (1998). Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J. Neurosci. 18, 5663-5672. (Pubitemid 28341346)
    • (1998) Journal of Neuroscience , vol.18 , Issue.15 , pp. 5663-5672
    • Conti, A.C.1    Raghupathi, R.2    Trojanowski, J.Q.3    McIntosh, T.K.4
  • 9
    • 0034520063 scopus 로고    scopus 로고
    • Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats
    • discussion 404-1396
    • Dempsey, R.J., Baskaya, M.K., and Dogan, A. (2000). Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats. Neurosurgery 47, 399-404; discussion 404-1396
    • (2000) Neurosurgery , vol.47 , pp. 399-404
    • Dempsey, R.J.1    Baskaya, M.K.2    Dogan, A.3
  • 11
    • 0345291173 scopus 로고    scopus 로고
    • Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion
    • DOI 10.1046/j.1471-4159.1999.0720765.x
    • Dogan, A., Rao, A.M., Hatcher, J., Rao, V.L., Baskaya, M.K., and Dempsey, R.J. (1999b). Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. J. Neurochem. 72, 765-770. (Pubitemid 29055241)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.2 , pp. 765-770
    • Dogan, A.1    Rao, A.M.2    Hatcher, J.3    Rao, V.L.R.4    Baskaya, M.K.5    Dempsey, R.J.6
  • 12
    • 0025977103 scopus 로고
    • Polyamine uptake, binding and release in rat brain
    • Gilad, G.M., and Gilad, V.H. (1991). Polyamine uptake, binding and release in rat brain. Eur. J. Pharmacol. 193, 41-46.
    • (1991) Eur. J. Pharmacol. , vol.193 , pp. 41-46
    • Gilad, G.M.1    Gilad, V.H.2
  • 13
    • 0026741533 scopus 로고
    • Polyamines in neurotrauma. Ubiquitous molecules in search of a function
    • Gilad, G.M., and Gilad, V.H. (1992). Polyamines in neurotrauma. Ubiquitous molecules in search of a function. Biochem. Pharmacol. 44, 401-407.
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 401-407
    • Gilad, G.M.1    Gilad, V.H.2
  • 14
    • 0027215449 scopus 로고
    • Accumulation of exogenous polyamines in gerbil brain after ischemia
    • Gilad, G.M., Gilad, V.H., and Wyatt, R.J. (1993). Accumulation of exogenous polyamines in gerbil brain after ischemia. Mol. Chem. Neuropathol. 18, 197-210.
    • (1993) Mol. Chem. Neuropathol. , vol.18 , pp. 197-210
    • Gilad, G.M.1    Gilad, V.H.2    Wyatt, R.J.3
  • 15
    • 0035863255 scopus 로고    scopus 로고
    • The polyamine stress response: Tissue-, endocrine-, and developmental- dependent regulation
    • Gilad, V.H., Rabey, J.M., Kimiagar, Y., and Gilad, G.M. (2001). The polyamine stress response: tissue-, endocrine-, and developmental- dependent regulation. Biochem. Pharmacol. 61, 207-213.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 207-213
    • Gilad, V.H.1    Rabey, J.M.2    Kimiagar, Y.3    Gilad, G.M.4
  • 17
    • 0029039988 scopus 로고
    • Polyamine induced Zconformation of native calf thymus, DNA
    • Hasan, R., Alam, M.K., and Ali, R. (1995). Polyamine induced Zconformation of native calf thymus, DNA. FEBS Lett. 368, 27-30.
    • (1995) FEBS Lett. , vol.368 , pp. 27-30
    • Hasan, R.1    Alam, M.K.2    Ali, R.3
  • 18
    • 0024145725 scopus 로고
    • Polyamines, DNA methylation and cell differentiation
    • Heby, O., Persson, L., and Smith, S.S. (1988). Polyamines, DNA methylation and cell differentiation. Adv. Exp. Med. Biol. 250, 291-299.
    • (1988) Adv. Exp. Med. Biol. , vol.250 , pp. 291-299
    • Heby, O.1    Persson, L.2    Smith, S.S.3
  • 19
    • 0023778242 scopus 로고
    • Glucocorticoid regulation of spermidine acetylation in the rat brain
    • Ientile, R., De Luca, G., Di Giorgio, R.M., and Macaione, S. (1988). Glucocorticoid regulation of spermidine acetylation in the rat brain. J. Neurochem. 51, 677-682.
    • (1988) J. Neurochem. , vol.51 , pp. 677-682
    • Ientile, R.1    De Luca, G.2    Di Giorgio, R.M.3    MacAione, S.4
  • 20
    • 33745714136 scopus 로고    scopus 로고
    • Physiological functions of polyamines and regulation of polyamine content in cells
    • In Japanese
    • Igarashi, K. (2006). [Physiological functions of polyamines and regulation of polyamine content in cells]. Yakugaku Zasshi 126, 455-471. [In Japanese]
    • (2006) Yakugaku Zasshi , vol.126 , pp. 455-471
    • Igarashi, K.1
  • 22
    • 0035055808 scopus 로고    scopus 로고
    • Regulation of SSAT expression by synaptic activity
    • DOI 10.1046/j.0953-816X.2001.01529.x
    • Ingi, T.,Worley, P.F., and Lanahan,A.A. (2001). Regulation of SSAT expression by synaptic activity. Eur. J. Neurosci. 13, 1459-1463. (Pubitemid 32328502)
    • (2001) European Journal of Neuroscience , vol.13 , Issue.7 , pp. 1459-1463
    • Ingi, T.1    Worley, P.F.2    Lanahan, A.A.3
  • 23
    • 0024459419 scopus 로고
    • 2+: Developmental changes
    • Jensen, J.R., Lynch, G., and Baudry, M. (1989). Allosteric activation of brain mitochondrial Ca2+ uptake by spermine and by Ca2+: developmental changes. J. Neurochem. 53, 1173-1181. (Pubitemid 19238485)
    • (1989) Journal of Neurochemistry , vol.53 , Issue.4 , pp. 1173-1181
    • Jensen, J.R.1    Lynch, G.2    Baudry, M.3
  • 24
    • 0141671958 scopus 로고    scopus 로고
    • 1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice
    • DOI 10.1016/S0014-4886(03)00186-9
    • Kaasinen, S.K., Grohn, O.H., Keinanen, T.A., Alhonen, L., and Janne, J. (2003). Overexpression of spermidine=spermine N1- acetyltransferase elevates the threshold to pentylenetetrazolinduced seizure activity in transgenic mice. Exp. Neurol. 183, 645-652. (Pubitemid 37205107)
    • (2003) Experimental Neurology , vol.183 , Issue.2 , pp. 645-652
    • Kaasinen, S.K.1    Grohn, O.H.J.2    Keinanen, T.A.3    Alhonen, L.4    Janne, J.5
  • 25
    • 0034050079 scopus 로고    scopus 로고
    • 1-acetyltransferase in transgenic mice protects the animals from kainate-induced toxicity
    • DOI 10.1046/j.1460-9568.2000.00940.x
    • Kaasinen, K., Koistinaho, J., Alhonen, L., and Janne, J. (2000). Overexpression of spermidine=spermine N-acetyltransferase in transgenic mice protects the animals from kainate-induced toxicity. Eur. J. Neurosci. 12, 540-548. (Pubitemid 30142755)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.2 , pp. 540-548
    • Kaasinen, K.1    Koistinaho, J.2    Alhonen, L.3    Janne, J.4
  • 26
    • 0022490910 scopus 로고
    • Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversedphase liquid chromatography: Improved separation systems for polyamines in cerebrospinal fluid, urine and tissue
    • Kabra, P.M., Lee, H.K., Lubich, W.P., and Marton, L.J. (1986). Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversedphase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue. J. Chromatogr. 380, 19-32.
    • (1986) J. Chromatogr. , vol.380 , pp. 19-32
    • Kabra, P.M.1    Lee, H.K.2    Lubich, W.P.3    Marton, L.J.4
  • 27
    • 0028138639 scopus 로고
    • Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage
    • Kindy, M.S., Hu, Y., and Dempsey, R.J. (1994). Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage. J. Cereb. Blood Flow Metab. 14, 1040-1045. (Pubitemid 24332949)
    • (1994) Journal of Cerebral Blood Flow and Metabolism , vol.14 , Issue.6 , pp. 1040-1045
    • Kindy, M.S.1    Hu, Y.2    Dempsey, R.J.3
  • 28
    • 0024508297 scopus 로고
    • Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: Both are coordinately inhibited by verapamil, dexamethasone, and aspirin
    • DOI 10.1111/j.1471-4159.1989.tb10903.x
    • Koenig, H., Goldstone, A.D., and Lu, C.Y. (1989). Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin. J. Neurochem. 52, 101-109. (Pubitemid 19023355)
    • (1989) Journal of Neurochemistry , vol.52 , Issue.1 , pp. 101-109
    • Koenig, H.1    Goldstone, A.D.2    Lu, C.Y.3
  • 29
    • 0022133358 scopus 로고
    • George e Brown memorial lecture. Oxygen radicals in cerebral vascular injury
    • Kontos, H.A. (1985). George E Brown memorial lecture. Oxygen radicals in cerebral vascular injury. Circ. Res. 57, 508-516.
    • (1985) Circ. Res. , vol.57 , pp. 508-516
    • Kontos, H.A.1
  • 30
    • 0027055209 scopus 로고
    • Endothelium-dependent responses after experimental brain injury
    • Kontos, H.A., and Wei, E.P. (1992). Endothelium-dependent responses after experimental brain injury. J.Neurotrauma 9, 349-354.
    • (1992) J.Neurotrauma , vol.9 , pp. 349-354
    • Kontos, H.A.1    Wei, E.P.2
  • 31
    • 42949166398 scopus 로고    scopus 로고
    • Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences
    • Kramer, D.L., Diegelman, P., Jell, J., Vujcic, S., Merali, S., and Porter, C.W. (2008). Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences. J. Biol. Chem. 283, 4241-4251.
    • (2008) J. Biol. Chem. , vol.283 , pp. 4241-4251
    • Kramer, D.L.1    Diegelman, P.2    Jell, J.3    Vujcic, S.4    Merali, S.5    Porter, C.W.6
  • 34
    • 34547472950 scopus 로고    scopus 로고
    • Polyamines in the brain: Distribution, biological interactions, and their potential therapeutic role in brain ischaemia
    • DOI 10.2174/092986707781058841
    • Li, J., Doyle, K.M., and Tatlisumak, T. (2007). Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia. Curr.Med. Chem. 14, 1807-1813. (Pubitemid 47163400)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.17 , pp. 1807-1813
    • Li, J.1    Doyle, K.M.2    Tatlisumak, T.3
  • 35
    • 0035205515 scopus 로고    scopus 로고
    • Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures
    • DOI 10.1046/j.1471-4159.2001.00650.x
    • Liu, W., Liu, R., Schreiber, S.S., and Baudry, M. (2001). Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures. J. Neurochem. 79, 976-984. (Pubitemid 33117076)
    • (2001) Journal of Neurochemistry , vol.79 , Issue.5 , pp. 976-984
    • Liu, W.1    Liu, R.2    Schreiber, S.S.3    Baudry, M.4
  • 36
    • 0038641715 scopus 로고    scopus 로고
    • 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
    • DOI 10.1042/BJ20021520
    • Li, W., Yuan, X.M., Ivanova, S., Tracey, K.J., Eaton, J.W., and Brunk, U.T. (2003). 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin. Biochem. J. 371, 429-436. (Pubitemid 36547626)
    • (2003) Biochemical Journal , vol.371 , Issue.2 , pp. 429-436
    • Li, W.1    Yuan, X.-M.2    Ivanova, S.3    Tracey, K.J.4    Eaton, J.W.5    Brunk, U.T.6
  • 37
    • 77956751037 scopus 로고    scopus 로고
    • Antioxidative and metal-chelating effects of polyamines
    • Lovaas, E. (1997). Antioxidative and metal-chelating effects of polyamines. Adv. Pharmacol. 38, 119-149.
    • (1997) Adv. Pharmacol. , vol.38 , pp. 119-149
    • Lovaas, E.1
  • 38
    • 0026039979 scopus 로고
    • Spermine: An anti-oxidant and anti-inflammatory agent
    • Lovaas, E., and Carlin, G. (1991). Spermine: an anti-oxidant and anti-inflammatory agent. Free Radic. Biol. Med. 11, 455-461.
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 455-461
    • Lovaas, E.1    Carlin, G.2
  • 39
    • 0028965842 scopus 로고
    • Rapid high-performance liquid chromatographic method for the quantitation of polyamines as their dansyl derivatives: Application to plant and animal tissues
    • Marcé, M., Brown, D.S., Capell, T., Figueras, X., and Tiburcio, A.F. (1995). Rapid high-performance liquid chromatographic method for the quantitation of polyamines as their dansyl derivatives: application to plant and animal tissues. J. Chromatogr. B Biomed. Appl. 666, 329-335.
    • (1995) J. Chromatogr. B Biomed. Appl. , vol.666 , pp. 329-335
    • Marcé, M.1    Brown, D.S.2    Capell, T.3    Figueras, X.4    Tiburcio, A.F.5
  • 40
    • 34247152992 scopus 로고    scopus 로고
    • Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats
    • DOI 10.1111/j.1530-0277.2007.00369.x
    • Mello, C.F., Rubin, M.A., Sultana, R., Barron, S., Littleton, J.M., and Butterfield, D.A. (2007). Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats. Alcohol Clin. Exp. Res. 31, 887-894. (Pubitemid 46587665)
    • (2007) Alcoholism: Clinical and Experimental Research , vol.31 , Issue.5 , pp. 887-894
    • Mello, C.F.1    Rubin, M.A.2    Sultana, R.3    Barron, S.4    Littleton, J.M.5    Butterfield, D.A.6
  • 41
    • 0035794108 scopus 로고    scopus 로고
    • Spermidine=spermine N1-acetyl transferase activity in rat brain following transient focal cerebral ischemia and reperfusion
    • Nagesh Babu, G.N., Sailor, K.A., Sun, D., and Dempsey, R.J. (2001). Spermidine=spermine N1-acetyl transferase activity in rat brain following transient focal cerebral ischemia and reperfusion. Neurosci. Lett. 300, 17-20.
    • (2001) Neurosci. Lett. , vol.300 , pp. 17-20
    • Nagesh Babu, G.N.1    Sailor, K.A.2    Sun, D.3    Dempsey, R.J.4
  • 42
    • 17444378253 scopus 로고    scopus 로고
    • Traumatic brain injury: A review
    • Nolan, S. (2005). Traumatic brain injury: a review. Crit. Care. Nurs. Q. 28, 188-194.
    • (2005) Crit. Care. Nurs. Q. , vol.28 , pp. 188-194
    • Nolan, S.1
  • 43
    • 0026744247 scopus 로고
    • Polyamine metabolism in different pathological states of the brain
    • Paschen, W. (1992). Polyamine metabolism in different pathological states of the brain. Mol. Chem. Neuropathol. 16, 241-271.
    • (1992) Mol. Chem. Neuropathol. , vol.16 , pp. 241-271
    • Paschen, W.1
  • 44
    • 0345267220 scopus 로고    scopus 로고
    • Increased ornithine decarboxylase activity and protein level in the cortex following traumatic brain injury in rats
    • Raghavendra Rao, V.L., Baskaya, M.K., Muralikrishna Rao, A., Dogan, A., and Dempsey, R.J. (1998). Increased ornithine decarboxylase activity and protein level in the cortex following traumatic brain injury in rats. Brain Res. 783, 163-166.
    • (1998) Brain Res. , vol.783 , pp. 163-166
    • Raghavendra Rao, V.L.1    Baskaya, M.K.2    Muralikrishna Rao, A.3    Dogan, A.4    Dempsey, R.J.5
  • 45
    • 0033621944 scopus 로고    scopus 로고
    • Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury
    • Rao, A.M., Hatcher, J.F., Dogan, A., and Dempsey, R.J. (2000). Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury. J. Neurochem. 74, 1106-1111.
    • (2000) J. Neurochem. , vol.74 , pp. 1106-1111
    • Rao, A.M.1    Hatcher, J.F.2    Dogan, A.3    Dempsey, R.J.4
  • 46
    • 0031981069 scopus 로고    scopus 로고
    • Hydrogen peroxide enhances signal-responsive arachidonic acid release from neurons: Role of mitogen-activated protein kinase
    • Samanta, S., Perkinton, M.S., Morgan, M., and Williams, R.J. (1998). Hydrogen peroxide enhances signal-responsive arachidonic acid release from neurons: role of mitogen-activated protein kinase. J. Neurochem. 70, 2082-2090.
    • (1998) J. Neurochem. , vol.70 , pp. 2082-2090
    • Samanta, S.1    Perkinton, M.S.2    Morgan, M.3    Williams, R.J.4
  • 47
    • 33749251817 scopus 로고    scopus 로고
    • Free radical scavenging action of the natural polyamine spermine in rat liver mitochondria
    • Sava, I.G., Battaglia, V., Rossi, C.A., Salvi, M., and Toninello, A. (2006). Free radical scavenging action of the natural polyamine spermine in rat liver mitochondria. Free Radic. Biol. Med. 41, 1272-1281.
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 1272-1281
    • Sava, I.G.1    Battaglia, V.2    Rossi, C.A.3    Salvi, M.4    Toninello, A.5
  • 48
    • 33645024412 scopus 로고    scopus 로고
    • Polyamine and aminoguanidine treatments to promote structural and functional recovery in the adult mammalian brain after injury: A brief literature review and preliminary data about their combined administration
    • Schimchowitsch, S., and Cassel, J.C. (2006). Polyamine and aminoguanidine treatments to promote structural and functional recovery in the adult mammalian brain after injury: a brief literature review and preliminary data about their combined administration. J. Physiol. Paris 99, 221-231.
    • (2006) J. Physiol. Paris , vol.99 , pp. 221-231
    • Schimchowitsch, S.1    Cassel, J.C.2
  • 49
    • 0027488026 scopus 로고
    • Difluoromethylornithine decreases postischemic brain edema and blood-brain barrier breakdown
    • discussion 887-888
    • Schmitz, M.P., Combs, D.J., and Dempsey, R.J. (1993). Difluoromethylornithine decreases postischemic brain edema and blood-brain barrier breakdown. Neurosurgery 33, 882- 887; discussion 887-888.
    • (1993) Neurosurgery , vol.33 , pp. 882-887
    • Schmitz, M.P.1    Combs, D.J.2    Dempsey, R.J.3
  • 50
    • 0034126310 scopus 로고    scopus 로고
    • Oxidation of polyamines and brain injury
    • Seiler, N. (2000). Oxidation of polyamines and brain injury. Neurochem. Res. 25, 471-490.
    • (2000) Neurochem. Res. , vol.25 , pp. 471-490
    • Seiler, N.1
  • 51
    • 0021922308 scopus 로고
    • Polyamine reutilization and turnover in brain
    • Seiler, N., and Bolkenius, F.N. (1985). Polyamine reutilization and turnover in brain. Neurochem. Res. 10, 529-544.
    • (1985) Neurochem. Res. , vol.10 , pp. 529-544
    • Seiler, N.1    Bolkenius, F.N.2
  • 52
    • 0016426935 scopus 로고
    • Interrelations between polyamines and nucleic acids: Changes of polyamine and nucleic acid concentrations in the developing rat brain
    • Seiler, N., and Lamberty, U. (1975). Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain. J. Neurochem. 24, 5-13.
    • (1975) J. Neurochem. , vol.24 , pp. 5-13
    • Seiler, N.1    Lamberty, U.2
  • 53
    • 0027450179 scopus 로고
    • Regulation of spermidine=spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis
    • Shappell, N.W., Fogel-Petrovic, M.F., and Porter, C.W. (1993). Regulation of spermidine=spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis. FEBS Lett. 321, 179-183.
    • (1993) FEBS Lett. , vol.321 , pp. 179-183
    • Shappell, N.W.1    Fogel-Petrovic, M.F.2    Porter, C.W.3
  • 54
    • 39449083733 scopus 로고    scopus 로고
    • Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging
    • Slemmer, J.E., Shacka, J.J., Sweeney, M.I., and Weber, J.T. (2008). Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Curr. Med. Chem. 15, 404-414.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 404-414
    • Slemmer, J.E.1    Shacka, J.J.2    Sweeney, M.I.3    Weber, J.T.4
  • 55
    • 0029867521 scopus 로고    scopus 로고
    • Effects of gestational or neonatal treatment with alpha- difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry
    • Sparapani, M., Virgili, M., Caprini, M., Facchinetti, F., Ciani, E., and Contestabile, A. (1996). Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry. Exp. Brain Res. 108, 433-440.
    • (1996) Exp. Brain Res. , vol.108 , pp. 433-440
    • Sparapani, M.1    Virgili, M.2    Caprini, M.3    Facchinetti, F.4    Ciani, E.5    Contestabile, A.6
  • 56
    • 23944478337 scopus 로고    scopus 로고
    • Oxidative metabolites are involved in polyamine-induced microglial cell death
    • Takano, K., Ogura, M., Yoneda, Y., and Nakamura, Y. (2005). Oxidative metabolites are involved in polyamine-induced microglial cell death. Neuroscience 134, 1123-1131.
    • (2005) Neuroscience , vol.134 , pp. 1123-1131
    • Takano, K.1    Ogura, M.2    Yoneda, Y.3    Nakamura, Y.4
  • 57
    • 0030600361 scopus 로고    scopus 로고
    • The contribution of endogenous polyamines to the permeability transition of rat liver mitochondria
    • Tassani, V., Campagnolo, M., Toninello, A., and Siliprandi, D. (1996). The contribution of endogenous polyamines to the permeability transition of rat liver mitochondria. Biochem. Biophys. Res. Commun. 226, 850-854.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 850-854
    • Tassani, V.1    Campagnolo, M.2    Toninello, A.3    Siliprandi, D.4
  • 58
    • 19744379831 scopus 로고    scopus 로고
    • Effect of difluoromethylornithine on reperfusion injury after temporary middle cerebral artery occlusion
    • Temiz, C., Dogan, A., Baskaya, M.K., and Dempsey, R.J. (2005). Effect of difluoromethylornithine on reperfusion injury after temporary middle cerebral artery occlusion. J. Clin. Neurosci. 12, 449-452.
    • (2005) J. Clin. Neurosci. , vol.12 , pp. 449-452
    • Temiz, C.1    Dogan, A.2    Baskaya, M.K.3    Dempsey, R.J.4
  • 59
    • 0029043692 scopus 로고
    • Polyamines and NMDA receptors modulate pericapillary astrocyte swelling following cerebral cryo-injury in the rat
    • Trout, J.J., Lu, C.Y., Goldstone, A.D., and Sahgal, S. (1995). Polyamines and NMDA receptors modulate pericapillary astrocyte swelling following cerebral cryo-injury in the rat. J. Neurocytol. 24, 341-346.
    • (1995) J. Neurocytol. , vol.24 , pp. 341-346
    • Trout, J.J.1    Lu, C.Y.2    Goldstone, A.D.3    Sahgal, S.4
  • 60
    • 3042584655 scopus 로고    scopus 로고
    • Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury
    • Wang, Z., Zahedi, K., Barone, S., Tehrani, K., Rabb, H., Matlin, K., Casero, R.A., and Soleimani, M. (2004). Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury. J. Am. Soc. Nephrol. 15, 1844-1852.
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 1844-1852
    • Wang, Z.1    Zahedi, K.2    Barone, S.3    Tehrani, K.4    Rabb, H.5    Matlin, K.6    Casero, R.A.7    Soleimani, M.8
  • 61
    • 0034646270 scopus 로고    scopus 로고
    • Mitochondrial dysfunction during hypoxia= reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates
    • Weinberg, J.M., Venkatachalam, M.A., Roeser, N.F., and Nissim, I. (2000a). Mitochondrial dysfunction during hypoxia= reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates. Proc. Natl. Acad. Sci. U.S.A. 97, 2826-2831.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 2826-2831
    • Weinberg, J.M.1    Venkatachalam, M.A.2    Roeser, N.F.3    Nissim, I.4
  • 63
    • 33744987653 scopus 로고    scopus 로고
    • Neurotoxicity of reactive aldehydes: The concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines
    • Wood, P.L., Khan, M.A., Kulow, S.R., Mahmood, S.A., and Moskal, J.R. (2006a). Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines. Brain Res. 1095, 190-199.
    • (2006) Brain Res. , vol.1095 , pp. 190-199
    • Wood, P.L.1    Khan, M.A.2    Kulow, S.R.3    Mahmood, S.A.4    Moskal, J.R.5
  • 64
    • 33947689120 scopus 로고    scopus 로고
    • The concept of "aldehyde load" in neurodegenerative mechanisms: Cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line
    • Wood, P.L., Khan, M.A., and Moskal, J.R. (2007). The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line. Brain Res. 1145, 150-156.
    • (2007) Brain Res. , vol.1145 , pp. 150-156
    • Wood, P.L.1    Khan, M.A.2    Moskal, J.R.3
  • 65
    • 33750743044 scopus 로고    scopus 로고
    • Aldehyde load in ischemia-reperfusion brain injury: Neuroprotection by neutralization of reactive aldehydes with phenelzine
    • Wood, P.L., Khan, M.A., Moskal, J.R., Todd, K.G., Tanay, V.A., and Baker, G. (2006b). Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine. Brain Res. 1122, 184-190.
    • (2006) Brain Res. , vol.1122 , pp. 184-190
    • Wood, P.L.1    Khan, M.A.2    Moskal, J.R.3    Todd, K.G.4    Tanay, V.A.5    Baker, G.6
  • 66
    • 27644509638 scopus 로고    scopus 로고
    • Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase
    • Xiong, Y., Shie, F.S., Zhang, J., Lee, C.P., and Ho, Y.S. (2005). Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase. J. Neurochem. 95, 732-744.
    • (2005) J. Neurochem. , vol.95 , pp. 732-744
    • Xiong, Y.1    Shie, F.S.2    Zhang, J.3    Lee, C.P.4    Ho, Y.S.5
  • 68
    • 0033276656 scopus 로고    scopus 로고
    • Spermine inhibition of monocyte activation and inflammation
    • Zhang, M., Borovikova, L.V., Wang, H., Metz, C., and Tracey, K.J. (1999). Spermine inhibition of monocyte activation and inflammation. Mol. Med. 5, 595-605.
    • (1999) Mol. Med. , vol.5 , pp. 595-605
    • Zhang, M.1    Borovikova, L.V.2    Wang, H.3    Metz, C.4    Tracey, K.J.5
  • 69
    • 0030965838 scopus 로고    scopus 로고
    • Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: A counterregulatory mechanism that restrains the immune response
    • Zhang, M., Caragine, T., Wang, H., Cohen, P.S., Botchkina, G., Soda, K., Bianchi, M., Ulrich, P., Cerami, A., Sherry, B., and Tracey, K.J. (1997). Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response. J. Exp. Med. 185, 1759-1768.
    • (1997) J. Exp. Med. , vol.185 , pp. 1759-1768
    • Zhang, M.1    Caragine, T.2    Wang, H.3    Cohen, P.S.4    Botchkina, G.5    Soda, K.6    Bianchi, M.7    Ulrich, P.8    Cerami, A.9    Sherry, B.10    Tracey, K.J.11
  • 71
    • 0025602902 scopus 로고
    • Evidence for a role of neosynthetized putrescine in the increase of glial fibrillary acidic protein immunoreactivity induced by a mechanical lesion in the rat brain
    • Zini, I., Zoli, M., Grimaldi, R., Pich, E.M., Biagini, G., Fuxe, K., and Agnati, L.F. (1990). Evidence for a role of neosynthetized putrescine in the increase of glial fibrillary acidic protein immunoreactivity induced by a mechanical lesion in the rat brain. Neurosci. Lett. 120, 13-16.
    • (1990) Neurosci. Lett. , vol.120 , pp. 13-16
    • Zini, I.1    Zoli, M.2    Grimaldi, R.3    Pich, E.M.4    Biagini, G.5    Fuxe, K.6    Agnati, L.F.7


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