Gap junctions and chagas disease

Advances in Parasitology

Volumn 76, Issue , 2011, Pages 63-81

  Adesse, Daniel ^a,b   Goldenberg, Regina Coeli ^a   Fortes, Fabio S ^c   Jasmin, ^b,d   Iacobas, Dumitru A ^d   Iacobas, Sanda ^d   Campos de Carvalho, Antonio Carlos ^a,d   de Narareth Meirelles, Maria ^b   Huang, Huan ^d   Soares, Milena B ^b   Tanowitz, Herbert B ^d   Garzoni, Luciana Ribeiro ^b   Spray, David C ^d  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Centro Universitário da Zona Oeste UEZO   (Brazil)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Arrhythmia; Astrocyte; Cx43; Gene expression connexin; Gja1; Heart; Intercellular communication; Tight junction

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; CONNEXIN 43; MESSENGER RNA; PROTEIN ZO1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

BOOK; CELL COMMUNICATION; CELL INVASION; CHAGAS DISEASE; GAP JUNCTION; GENE EXPRESSION; HEART FUNCTION; HEART MUSCLE CELL; HISTOPATHOLOGY; HOST CELL; HUMAN; IMMUNOREACTIVITY; IN VITRO STUDY; MICROARRAY ANALYSIS; NONHUMAN; PARASITISM; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; TRANSCRIPTOMICS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 80052147660     PISSN: 0065308X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385895-5.00003-7     Document Type: Chapter

References (54)

1. Adesse D., Garzoni L.R., Huang H., Tanowitz H.B., de Nazareth Meirelles M., Spray D.C. Trypanosoma cruzi induces changes in cardiac connexin43 expression. Microbes Infect. 2008, 10:21-28.
2. Adesse D., Iacobas D.A., Iacobas S., Garzoni L.R., Meirelles Mde N., Tanowitz H.B., et al. Transcriptomic signatures of alterations in a myoblast cell line infected with four distinct strains of Trypanosoma cruzi. Am. J. Trop. Med. Hyg. 2010, 82:846-854.
3. Adesse D., Azzam E.M., Meirelles Mde N., Urbina J.A., Garzoni L.R.A. Miodarone inhibits Trypanosoma cruzi infection and promotes cardiac cell recovery with gap junction and cytoskeleton reassembly in vitro. Antimicrob. Agents Chemother. 2011, 55:203-210.
4. Akar F.G., Spragg D.D., Tunin R.S., Kass D.A., Tomaselli G.F. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circ. Res. 2004, 1:717-725.
5. Andrade L.O., Andrews N.W. Lysosomal fusion is essential for the retention of Trypanosoma cruzi inside host cells. J. Exp. Med. 2004, 1:1135-1143.
6. Aprigliano O., Masuda M.O., Meirelles M.N., Pereira M.C., Barbosa H.S., Barbosa J.C. Heart muscle cells acutely infected with Trypanosoma cruzi: characterization of electrophysiology and neurotransmitter responses. J. Mol. Cell. Cardiol. 1993, 25:1265-1274.
7. Araújo-Jorge T.C., Waghabi M.C., Soeiro Mde N., Keramidas M., Bailly S., Feige J.J. Pivotal role for TGF-beta in infectious heart disease: the case of Trypanosoma cruzi infection and consequent Chagasic myocardiopathy. Cytokine Growth Factor Rev. 2008, 19:405-413.
8. Benaim G., Sanders J.M., Garcia-Marchán Y., Colina C., Lira R., Caldera A.R., et al. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. J. Med. Chem. 2006, 9:892-899.
9. Bergdolt B.A., Tanowitz H.B., Wittner M., Morris S.A., Bilezikian J.P., Moreno A.P., et al. Trypanosoma cruzi: effects of infection on receptor-mediated chronotropy and Ca2+ mobilization in rat cardiac myocytes. Exp. Parasitol. 1994, 78:149-160.
10. Caetano L.C., do Prado J.C., Toldo M.P., Abrahão A.A. Trypanosoma cruzi: do different sylvatic strains trigger distinct immune responses?. Exp. Parasitol. 2010, 124:219-224.
11. Campos de Carvalho A.C., Roy C., Hertzberg E.L., Tanowitz H.B., Kessler J.A., Weiss L.M., et al. Gap junction disappearance in astrocytes and leptomeningeal cells as a consequence of protozoan infection. Brain Res. 1998, 790:304-314.
12. Celes M.R., Torres-Dueñas D., Alves-Filho J.C., Duarte D.B., Cunha F.Q., Rossi M.A. Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis. Crit. Care Med. 2007, 35:2176-2185.
13. Chaldoupi S.M., Loh P., Hauer R.N., de Bakker J.M., van Rijen H.V. The role of connexin40 in atrial fibrillation. Cardiovasc. Res. 2009, 84:15-23.
14. Chandross K.J., Chanson M., Spray D.C., Kessler J.A. Transforming growth factor-beta 1 and forskolin modulate gap junctional communication and cellular phenotype of cultured Schwann cells. J. Neurosci. 1995, 15:262-273.
15. Chanson M., Derouette J.P., Roth I., Foglia B., Scerri I., Dudez T., et al. Gap junctional communication in tissue inflammation and repair. Biochim. Biophys. Acta 2005, 1711:197-207.
16. Costa P.C., Fortes F.S., Machado A.B., Almeida N.A., Olivares E.L., Cabral P.R., et al. Sera from chronic chagasic patients depress cardiac electrogenesis and conduction. Braz. J. Med. Biol. Res. 2000, 33:439-446.
17. Courchesne W.E. Characterization of a novel, broad-based fungicidal activity for the antiarrhythmic drug amiodarone. J. Pharmacol. Exp. Ther. 2002, 300:195-199.
18. Courchesne W.E., Tunc M., Liao S. Amiodarone induces stress responses and calcium flux mediated by the cell wall in Saccharomyces cerevisiae. Can. J. Microbiol. 2009, 55:288-303.
19. de Carvalho A.C., Tanowitz H.B., Wittner M., Dermietzel R., Roy C., Hertzberg E.L., et al. Gap junction distribution is altered between cardiac myocytes infected with Trypanosoma cruzi. Circ. Res. 1992, 70:733-742.
20. de Carvalho A.C., Masuda M.O., Tanowitz H.B., Wittner M., Goldenberg R.C., Spray D.C. Conduction defects and arrhythmias in Chagas' disease: possible role of gap junctions and humoral mechanisms. J. Cardiovasc. Electrophysiol. 1994, 5:686-698.
21. Dubner S., Schapachnik E., Riera A.R., Valero E. Chagas disease: state-of-the-art of diagnosis and management. Cardiol. J. 2008, 15:493-504.
22. Duffy H.S., Fort A., Spray D.C. Cardiac connexins: genes to nexus. Adv. Cardiol. 2006, 42:1-17.
23. Garzoni L.R., Masuda M.O., Capella M.M., Lopes A.G., de Meirelles Mde N. Characterization of [Ca2+]i responses in primary cultures of mouse cardiomyocytes induced by Trypanosoma cruzi trypomastigotes. Mem. Inst. Oswaldo Cruz 2003, 98:487-493.
24. Giepmans B.N., Moolenaar W.H. The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr. Biol. 1998, 13:931-934.
25. Goldenberg R.C., Iacobas D.A., Iacobas S., Rocha L.L., da Silva de Azevedo Fortes F., Vairo L., et al. Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes. Microbes Infect. 2009, 11:1140-1149.
26. Goodenough D.A., Goliger J.A., Paul D.L. Connexins, connexons, and intercellular communication. Annu. Rev. Biochem. 1996, 65:475-502.
27. Hervé J.C., Bourmeyster N., Sarrouilhe D. Diversity in protein-protein interactions of connexins: emerging roles. Biochim. Biophys. Acta 2004, 23:22-41.
28. Hossain M.Z., Sawchuk M.A., Murphy L.J., Hertzberg E.L., Nagy J.I. Kainic acid induced alterations in antibody recognition of connexin43 and loss of astrocytic gap junctions in rat brain. Glia 1994, 10:250-265.
29. Iacobas D.A., Iacobas S., Thomas N., Spray D.C. Sex-dependent gene regulatory networks of the heart rhythm. Funct. Integr. Genomics 2010, 10:73-86.
30. Iacobas D.A., Iacobas S., Haddad G.G. Heart rhythm genomic fabric in hypoxia. Biochem. Biophys. Res. Commun. 2010, 391(4):1769-1774.
31. Manque P.A., Probst C., Pereira M.C.S., Rampazzo R.C.P., Ozaki L.S., Pavoni D.P., et al. Trypanosoma cruzi infection induces a global host cell response in cardiomyocytes. Infect. Immun. 2011, 79:1855-1862.
32. Marin-Neto J.A., Cunha-Neto E., Maciel B.C., Simões M.V. Pathogenesis of chronic Chagas heart disease. Circulation 2007, 115:1109-1123.
33. Mukherjee S., Belbin T.J., Spray D.C., Iacobas D.A., Weiss L.M., Kitsis R.N., et al. Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy. Parasitol. Res. 2003, 91:187-196.
34. Mukherjee S., Nagajyothi F., Mukhopadhyay A., Machado F.S., Belbin T.J., Campos de Carvalho A., et al. Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection. Genomics 2008, 91:423-432.
35. Ramos-Mondragón R., Galindo C.A., Avila G. Role of TGF-beta on cardiac structural and electrical remodeling. Vasc. Health Risk Manag. 2008, 4:1289-1300.
36. Rodriguez A., Rioult M.G., Ora A., Andrews N.W. A trypanosome-soluble factor induces IP3 formation, intracellular Ca2+ mobilization and microfilament rearrangement in host cells. J. Cell Biol. 1995, 129:1263-1273.
37. Saffitz J.E., Hames K.Y., Kanno S. Remodeling of gap junctions in ischemic and nonischemic forms of heart disease. J. Membr. Biol. 2007, 218:65-71.
38. Schweizer P.A., Becker R., Katus H.A., Thomas D. Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation. Drug Des. Dev. Ther. 2011, 5:27-39.
39. Seidel T., Salameh A., Dhein S. A simulation study of cellular hypertrophy and connexin lateralization in cardiac tissue. Biophys. J. 2010, 99:2821-2830.
40. Serrano-Martín X., García-Marchan Y., Fernandez A., Rodriguez N., Rojas H., Visbal G., et al. Amiodarone destabilizes intracellular Ca2+ homeostasis and biosynthesis of sterols in Leishmania mexicana. Antimicrob. Agents Chemother. 2009, 53:1403-1410.
41. Severs N.J. Gap junction remodeling and cardiac arrhythmogenesis: cause or coincidence?. J. Cell. Mol. Med. 2001, 5:355-366.
42. Severs N.J., Dupont E., Thomas N., Kaba R., Rothery S., Jain R., et al. Alterations in cardiac connexin expression in cardiomyopathies. Adv. Cardiol. 2006, 42:228-242.
43. Soares M.B., de Lima R.S., Rocha L.L., Vasconcelos J.F., Rogatto S.R., dos Santos R.R., et al. Gene expression changes associated with myocarditis and fibrosis in hearts of mice with chronic chagasic cardiomyopathy. J. Infect. Dis. 2010, 15:416-426.
44. Söhl G., Willecke K. Gap junctions and the connexin protein family. Cardiovasc. Res. 2004, 1:228-232.
45. Sorgen P.L., Duffy H.S., Sahoo P., Coombs W., Delmar M., Spray D.C. Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1. J. Biol. Chem. 2004, 279:54695-54701.
46. Spray D.C., Tanowitz H.B. Pathology of mechanical and gap junctional co-coupling at the intercalated disc: is sepsis a junctionopathy?. Crit. Care Med. 2007, 35:2231-2232.
47. Spray D.C., Suadicani S.O., Vink M.J., Srinivas M. Gap junction channels and healing-over of injury. Heart Physiology and Pathophysiology 2001, 149-172. Academic Press, New York. N. Sperelakis, Y. Kurachi, A. Terzic, M.V. Cohen (Eds.).
48. Tanowitz H.B., Kirchhoff L.V., Simon D., Morris S.A., Weiss L.M., Wittner M. Chagas' disease. Clin. Microbiol. Rev. 1992, 5:400-419.
49. Tanowitz H.B., Machado F.S., Jelicks L.A., Shirani J., de Carvalho A.C., Spray D.C., et al. Perspectives on Trypanosoma cruzi-induced heart disease (Chagas disease). Prog. Cardiovasc. Dis. 2009, 51:524-539.
50. Toyofuku T., Yabuki M., Otsu K., Kuzuya T., Hori M., Tada M. Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J. Biol. Chem. 1998, 273:12725-12731.
51. Van Herendael H., Dorian P. Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia. Vasc. Health Risk Manag. 2010, 6:465-472.
52. Waghabi M.C., Coutinho-Silva R., Feige J.J., Higuchi Mde L., Becker D., Burnstock G., et al. Gap junction reduction in cardiomyocytes following transforming growth factor-beta treatment and Trypanosoma cruzi infection. Mem. Inst. Oswaldo Cruz 2009, 104:1083-1090.
53. Wang D., Zhang F., Shen W., Chen M., Yang B., Zhang Y., et al. Mesenchymal stem cell injection ameliorates the inducibility of ventricular arrhythmias after myocardial infarction in rats. Int. J. Cardiol. 2010, (in press).
54. Yarnold J., Brotons M.C. Pathogenetic mechanisms in radiation fibrosis. Radiother. Oncol. 2010, 97:149-161.