Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Najumudeen, Arafath Kaja ^a   Köhnke, Monika ^b   Šolman, Maja ^a   Alexandrov, Kirill ^b   Abankwa, Daniel ^a,b  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; CURVULARIN; CYTOSPORONE B; DDD 85646; FLAGRANONE A; FUMAGILLIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INTEGRACIN A; LACTONE DERIVATIVE; PROTEIN KINASE YES; PROTEIN N MYRISTOYLTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE; PSEUDOMONIC ACID; REVEROMYCIN A; REVEROMYCIN B; TETRADECANOYL LEVO HOMOSERINE LACTONE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; MYRISTIC ACID;

ANIMAL CELL; ARTICLE; BIOSENSOR; CELL ANCHORAGE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; EMBRYO; EQUIPMENT DESIGN; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MAMMAL CELL; MYRISTYLATION; NANOCLUSTERING AND MYRISTOYLATION SENSOR; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; CELL LINE; CLUSTER ANALYSIS; GENETIC PROCEDURES; HAMSTER; METABOLISM;

EUKARYOTA; MAMMALIA;

ANIMALS; BIOSENSING TECHNIQUES; CELL LINE; CELL MEMBRANE; CLUSTER ANALYSIS; CRICETINAE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; MEMBRANE PROTEINS; MYRISTIC ACID;

EID: 84879152912     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066425     Document Type: Article

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