Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors

Chemistry and Biology

Volumn 19, Issue 7, 2012, Pages 866-874

  Köhnke, Monika ^a   Schmitt, Steven ^a,c   Ariotti, Nicholas ^a   Piggott, Andrew M ^a   Parton, Robert G ^a   Lacey, Ernest ^b   Capon, Robert J ^a   Alexandrov, Kirill ^a   Abankwa, Daniel ^a,d  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b MICROBIAL SCREENING TECHNOLOGIES PTY LTD   (Australia)

^c ETH ZURICH   (Switzerland)

^d ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDE; MITOGEN ACTIVATED PROTEIN KINASE; RAB PROTEIN; RAS PROTEIN; RHO FACTOR;

ARTICLE; BIOSENSOR; CELL ASSAY; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; IN VIVO STUDY; NANOCLUSTERING AND PENYLATION SENSOR; PROTEIN PRENYLATION; SIGNAL TRANSDUCTION;

ANIMALS; BIOSENSING TECHNIQUES; CELLS, CULTURED; CRICETINAE; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELLS; HUMANS; PROTEIN PRENYLATION; RAB GTP-BINDING PROTEINS; RAS PROTEINS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84864408572     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.05.019     Document Type: Article

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