The plasma membrane of bloodstream-form African trypanosomes confers susceptibility and specificity to killing by hydrophobic peptides

Journal of Biological Chemistry

Volumn 285, Issue 37, 2010, Pages 28659-28666

  Harrington, John M ^a   Widener, Justin ^a   Stephens, Natalie ^a   Johnson, Thomas ^a   Francia, Maria ^a   Capewell, Paul ^b   Macleod, Annette ^b   Hajduk, Stephen L ^a  

^a Dept of Biochemistry and Molecular Biology University of Georgia B129 Life Sciences Bldg ^*  (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; CELL MEMBRANES; FLUIDITY; HYDROPHOBICITY; LIPID BILAYERS; LIPOSOMES; MAMMALS; MEMBRANES; PHOSPHOLIPIDS; POPULATION STATISTICS; RIGIDITY;

AFRICAN TRYPANOSOMES; APOLIPOPROTEINS; BI-LAYER; CAUSATIVE AGENTS; DEVELOPMENTAL STAGE; GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED PROTEINS; HYDROPHOBIC PEPTIDES; IN-CELL; LATERAL FLOW; MAMMALIAN CELL LINES; MAMMALIAN HOSTS; N-TERMINALS; PLASMA MEMBRANES; RAPID RATE; SIGNAL SEQUENCE; SLEEPING SICKNESS; TRYPANOSOMA BRUCEI;

PEPTIDES;

ANTITRYPANOSOMAL AGENT; APOLIPOPROTEIN; ARYLDIALKYLPHOSPHATASE 1; LIPOSOME; POLYPEPTIDE ANTIBIOTIC AGENT; SMALL HYDROPHOBIC PEPTIDE 1; SMALL HYDROPHOBIC PEPTIDE 2; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL DEATH; CELL KILLING; CELL MEMBRANE; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DRUG CYTOTOXICITY; HEMOLYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIPID BILAYER; MEMBRANE FLUIDITY; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA GAMBIENSE; TRYPANOSOMA RHODESIENSE; ANIMAL; CHEMICAL PHENOMENA; DRUG EFFECTS; ENDOCYTOSIS; METABOLISM; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN; TUMOR CELL LINE;

HEXAPODA; MAMMALIA; TRYPANOSOMA BRUCEI;

ANIMALS; ANTIPROTOZOAL AGENTS; APOLIPOPROTEINS; CELL LINE, TUMOR; CELL MEMBRANE; ENDOCYTOSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOSOMES; MEMBRANE FLUIDITY; PROTEIN SORTING SIGNALS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

EID: 77956514977     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.151886     Document Type: Article

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