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Volumn 28, Issue 6, 2013, Pages 691-699

Mast cell chymase: An indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

Author keywords

Angiotensin II; Chymase; Mast cells; Pulmonary fibrosis; TGF

Indexed keywords

BIOLOGICAL MARKER; CHYMASE;

EID: 84878988452     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (12)

References (92)
  • 1
    • 0030883691 scopus 로고    scopus 로고
    • Increased levels of endothelin-1 and differential endothelin type A and B receptor expression in scleroderma-associated fibrotic lung disease
    • Abraham D.J., Vancheeswaran R., Dashwood M.R., Rajkumar V.S., Pantelides P., Xu S.W., du Bois R.M. and Black C.M. (1997). Increased levels of endothelin-1 and differential endothelin type A and B receptor expression in scleroderma-associated fibrotic lung disease. Am. J. Pathol. 151, 831-841.
    • (1997) Am. J. Pathol. , vol.151 , pp. 831-841
    • Abraham, D.J.1    Vancheeswaran, R.2    Dashwood, M.R.3    Rajkumar, V.S.4    Pantelides, P.5    Xu, S.W.6    du Bois, R.M.7    Black, C.M.8
  • 7
    • 0030952324 scopus 로고    scopus 로고
    • Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts
    • Cairns J.A. and Walls A.F. (1997). Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J. Clin. Invest. 99, 1313-1321.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1313-1321
    • Cairns, J.A.1    Walls, A.F.2
  • 8
    • 0034647653 scopus 로고    scopus 로고
    • Angiotensin II generation by mast cell alpha-and beta-chymases
    • Caughey G.H., Raymond W.W. and Wolters P.J. (2000). Angiotensin II generation by mast cell alpha-and beta-chymases. Biochim. Biophys. Acta 1480, 245-257.
    • (2000) Biochim. Biophys. Acta , vol.1480 , pp. 245-257
    • Caughey, G.H.1    Raymond, W.W.2    Wolters, P.J.3
  • 12
    • 79960189227 scopus 로고    scopus 로고
    • Metalloproteinases in idiopathic pulmonary fibrosis
    • Dancer R.C., Wood A.M. and Thickett D.R. (2011). Metalloproteinases in idiopathic pulmonary fibrosis. Eur. Respir. J. 38, 1461-1467.
    • (2011) Eur. Respir. J. , vol.38 , pp. 1461-1467
    • Dancer, R.C.1    Wood, A.M.2    Thickett, D.R.3
  • 13
    • 0023266455 scopus 로고
    • Measurement of the internal pH of mast cell granules using microvolumetric fluorescence and isotopic techniques
    • De Young M.B., Nemeth E.F. and Scarpa A. (1987). Measurement of the internal pH of mast cell granules using microvolumetric fluorescence and isotopic techniques. Arch. Biochem. Biophys. 254, 222-233.
    • (1987) Arch. Biochem. Biophys. , vol.254 , pp. 222-233
    • de Young, M.B.1    Nemeth, E.F.2    Scarpa, A.3
  • 14
    • 1342281660 scopus 로고    scopus 로고
    • Vascular chymase: Pathophysiological role and therapeutic potential of inhibition
    • Doggrell S.A. and Wanstall J.C. (2004). Vascular chymase: pathophysiological role and therapeutic potential of inhibition. Cardiovasc. Res. 61, 653-662.
    • (2004) Cardiovasc. Res. , vol.61 , pp. 653-662
    • Doggrell, S.A.1    Wanstall, J.C.2
  • 15
    • 84865113809 scopus 로고    scopus 로고
    • New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis
    • Fernandez I.E. and Eickelberg O. (2012). New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis. Lancet 380, 680-688.
    • (2012) Lancet , vol.380 , pp. 680-688
    • Fernandez, I.E.1    Eickelberg, O.2
  • 16
    • 0034749878 scopus 로고    scopus 로고
    • Morphological and biochemical properties of alveolar fibroblasts in interstitial lung diseases
    • Fireman E., Shahar I., Shoval S., Messer G., Dvash S. and Grief J. (2001). Morphological and biochemical properties of alveolar fibroblasts in interstitial lung diseases. Lung 179, 105-117.
    • (2001) Lung , vol.179 , pp. 105-117
    • Fireman, E.1    Shahar, I.2    Shoval, S.3    Messer, G.4    Dvash, S.5    Grief, J.6
  • 19
    • 36849094534 scopus 로고    scopus 로고
    • Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis
    • Galli S.J. and Tsai M. (2008). Mast cells: versatile regulators of inflammation, tissue remodeling, host defense and homeostasis. J. Dermatol. Sci. 49, 7-19.
    • (2008) J. Dermatol. Sci. , vol.49 , pp. 7-19
    • Galli, S.J.1    Tsai, M.2
  • 26
    • 70949103587 scopus 로고    scopus 로고
    • Role of proinflammatory cytokines IL-18 and IL-1beta in bleomycin-induced lung injury in humans and mice
    • Hoshino T., Okamoto M., Sakazaki Y., Kato S., Young H.A. and Aizawa H. (2009). Role of proinflammatory cytokines IL-18 and IL-1beta in bleomycin-induced lung injury in humans and mice. Am. J. Respir. Cell Mol. Biol. 41, 661-670.
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.41 , pp. 661-670
    • Hoshino, T.1    Okamoto, M.2    Sakazaki, Y.3    Kato, S.4    Young, H.A.5    Aizawa, H.6
  • 27
    • 0026646186 scopus 로고
    • Immunofluorescent staining for mast cells in idiopathic pulmonary fibrosis: Quantification and evidence for extracellular release of mast cell tryptase
    • Hunt L.W., Colby T.V., Weiler D.A., Sur S. and Butterfield J.H. (1992). Immunofluorescent staining for mast cells in idiopathic pulmonary fibrosis: quantification and evidence for extracellular release of mast cell tryptase. Mayo. Clin. Proc. 67, 941-948.
    • (1992) Mayo. Clin. Proc. , vol.67 , pp. 941-948
    • Hunt, L.W.1    Colby, T.V.2    Weiler, D.A.3    Sur, S.4    Butterfield, J.H.5
  • 28
    • 0029844941 scopus 로고    scopus 로고
    • Human mast cell basic fibroblast growth factor in pulmonary fibrotic disorders
    • Inoue Y., King T.E. Jr, Tinkle S.S., Dockstader K. and Newman L.S. (1996). Human mast cell basic fibroblast growth factor in pulmonary fibrotic disorders. Am. J. Pathol. 149, 2037-2054.
    • (1996) Am. J. Pathol. , vol.149 , pp. 2037-2054
    • Inoue, Y.1    King Jr., T.E.2    Tinkle, S.S.3    Dockstader, K.4    Newman, L.S.5
  • 30
    • 77951221971 scopus 로고    scopus 로고
    • Transforming growth factor-'1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts
    • Jablonska E., Markart P., Zakrzewicz D., Preissner K.T. and Wygrecka M. (2010). Transforming growth factor-'1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts. J. Biol. Chem. 285, 11638-11651.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11638-11651
    • Jablonska, E.1    Markart, P.2    Zakrzewicz, D.3    Preissner, K.T.4    Wygrecka, M.5
  • 31
    • 0025984699 scopus 로고
    • The role of TGF-beta in pulmonary fibrosis
    • Khalil N. and Greenberg A.H. (1991). The role of TGF-beta in pulmonary fibrosis. Ciba. Found. Symp. 157, 194-207.
    • (1991) Ciba. Found. Symp. , vol.157 , pp. 194-207
    • Khalil, N.1    Greenberg, A.H.2
  • 32
    • 82755161052 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis
    • King T.E. Jr, Pardo A. and Selman M. (2011). Idiopathic pulmonary fibrosis. Lancet 378, 1949-1961.
    • (2011) Lancet , vol.378 , pp. 1949-1961
    • King Jr., T.E.1    Pardo, A.2    Selman, M.3
  • 34
    • 0030897985 scopus 로고    scopus 로고
    • Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide
    • Kofford M.W., Schwartz L.B., Schechter N.M., Yager D.R., Diegelmann R.F. and Graham M.F. (1997). Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide. J. Biol. Chem. 272, 7127-7131.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7127-7131
    • Kofford, M.W.1    Schwartz, L.B.2    Schechter, N.M.3    Yager, D.R.4    Diegelmann, R.F.5    Graham, M.F.6
  • 38
    • 80052341059 scopus 로고    scopus 로고
    • Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria
    • Kordes M., Matuschewski K. and Hafalla J.C. (2011). Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect. Immun. 79, 3633-3641.
    • (2011) Infect. Immun. , vol.79 , pp. 3633-3641
    • Kordes, M.1    Matuschewski, K.2    Hafalla, J.C.3
  • 41
    • 75749141625 scopus 로고    scopus 로고
    • Chymase mediates paraquat-induced collagen production in human lung fibroblasts
    • Lang Y.D., Chang S.F., Wang L.F. and Chen C.M. (2010). Chymase mediates paraquat-induced collagen production in human lung fibroblasts. Toxicol. Lett. 193, 19-25.
    • (2010) Toxicol. Lett. , vol.193 , pp. 19-25
    • Lang, Y.D.1    Chang, S.F.2    Wang, L.F.3    Chen, C.M.4
  • 47
    • 0033571072 scopus 로고    scopus 로고
    • Anti-TGFbeta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: A model for human scleroderma
    • McCormick L.L., Zhang Y., Tootell E. and Gilliam A.C. (1999). Anti-TGFbeta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma. J. Immunol. 163, 5693-5699.
    • (1999) J. Immunol. , vol.163 , pp. 5693-5699
    • McCormick, L.L.1    Zhang, Y.2    Tootell, E.3    Gilliam, A.C.4
  • 48
    • 0029020946 scopus 로고
    • Regulation of the activity of human chymase during storage and release from mast cells: The contributions of inorganic cations, pH, heparin and histamine
    • McEuen A.R., Sharma B. and Walls A.F. (1995). Regulation of the activity of human chymase during storage and release from mast cells: the contributions of inorganic cations, pH, heparin and histamine. Biochim. Biophys. Acta 1267, 115-121.
    • (1995) Biochim. Biophys. Acta , vol.1267 , pp. 115-121
    • McEuen, A.R.1    Sharma, B.2    Walls, A.F.3
  • 49
    • 58849094483 scopus 로고    scopus 로고
    • MMP expression and abnormal lung permeability are important determinants of outcome in IPF
    • McKeown S., Richter A.G., O'Kane C., McAuley D.F. and Thickett D.R. (2009). MMP expression and abnormal lung permeability are important determinants of outcome in IPF. Eur. Respir. J. 33, 77-84.
    • (2009) Eur. Respir. J. , vol.33 , pp. 77-84
    • McKeown, S.1    Richter, A.G.2    O'Kane, C.3    McAuley, D.F.4    Thickett, D.R.5
  • 51
    • 33747588568 scopus 로고    scopus 로고
    • Tissue angiotensin II generating system by angiotensin-converting enzyme and chymase
    • Miyazaki M. and Takai S. (2006a). Tissue angiotensin II generating system by angiotensin-converting enzyme and chymase. J. Pharmacol. Sci. 100, 391-397.
    • (2006) J. Pharmacol. Sci. , vol.100 , pp. 391-397
    • Miyazaki, M.1    Takai, S.2
  • 52
    • 33750032795 scopus 로고    scopus 로고
    • Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models
    • Miyazaki M., Takai S., Jin D. and Muramatsu M. (2006b). Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models. Pharmacol. Ther. 112, 668-676.
    • (2006) Pharmacol. Ther. , vol.112 , pp. 668-676
    • Miyazaki, M.1    Takai, S.2    Jin, D.3    Muramatsu, M.4
  • 53
    • 0026040529 scopus 로고
    • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase
    • Mizutani H., Schechter N., Lazarus G., Black R.A. and Kupper T.S. (1991). Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J. Exp. Med. 174, 821-825.
    • (1991) J. Exp. Med. , vol.174 , pp. 821-825
    • Mizutani, H.1    Schechter, N.2    Lazarus, G.3    Black, R.A.4    Kupper, T.S.5
  • 54
    • 39149103740 scopus 로고    scopus 로고
    • The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?
    • Moeller A., Ask K., Warburton D., Gauldie J. and Kolb M. (2008). The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? Int. J. Biochem. Cell Biol. 40, 362-382.
    • (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 362-382
    • Moeller, A.1    Ask, K.2    Warburton, D.3    Gauldie, J.4    Kolb, M.5
  • 55
    • 0032063366 scopus 로고    scopus 로고
    • Increased endothelin-1 and its localization during the development of bleomycin-induced pulmonary fibrosis in rats
    • Mutsaers S.E., Foster M.L., Chambers R.C., Laurent G.J. and McAnulty R.J. (1998). Increased endothelin-1 and its localization during the development of bleomycin-induced pulmonary fibrosis in rats. Am. J. Respir. Cell Mol. Biol. 18, 611-619.
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.18 , pp. 611-619
    • Mutsaers, S.E.1    Foster, M.L.2    Chambers, R.C.3    Laurent, G.J.4    McAnulty, R.J.5
  • 57
    • 80053144553 scopus 로고    scopus 로고
    • Chymase inhibition reduces infarction and matrix metalloproteinase-9 activation and attenuates inflammation and fibrosis after acute myocardial ischemia/reperfusion
    • Oyamada S., Bianchi C., Takai S., Chu L.M. and Sellke F.W. (2011). Chymase inhibition reduces infarction and matrix metalloproteinase-9 activation and attenuates inflammation and fibrosis after acute myocardial ischemia/reperfusion. J. Pharmacol. Exp. Ther. 339, 143-151.
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 143-151
    • Oyamada, S.1    Bianchi, C.2    Takai, S.3    Chu, L.M.4    Sellke, F.W.5
  • 58
    • 0030755489 scopus 로고    scopus 로고
    • Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist
    • Park S.H., Saleh D., Giaid A. and Michel R.P. (1997). Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist. Am. J. Respir. Crit. Care Med. 156, 600-608.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 600-608
    • Park, S.H.1    Saleh, D.2    Giaid, A.3    Michel, R.P.4
  • 59
    • 77954663588 scopus 로고    scopus 로고
    • Mast cell proteases: Multifaceted regulators of inflammatory disease
    • Pejler G., Ronnberg E., Waern I. and Wernersson S. (2010). Mast cell proteases: multifaceted regulators of inflammatory disease. Blood 115, 4981-4990.
    • (2010) Blood , vol.115 , pp. 4981-4990
    • Pejler, G.1    Ronnberg, E.2    Waern, I.3    Wernersson, S.4
  • 63
    • 34248229692 scopus 로고    scopus 로고
    • Renin: At the heart of the mast cell
    • Reid A.C., Silver R.B. and Levi R. (2007). Renin: at the heart of the mast cell. Immunol. Rev. 217, 123-140.
    • (2007) Immunol. Rev. , vol.217 , pp. 123-140
    • Reid, A.C.1    Silver, R.B.2    Levi, R.3
  • 64
    • 39049153440 scopus 로고    scopus 로고
    • Extended substrate specificity of opossum chymase-implications for the origin of mast cell chymases
    • Reimer J.M., Enoksson M., Samollow P.B. and Hellman L. (2008). Extended substrate specificity of opossum chymase-implications for the origin of mast cell chymases. Mol. Immunol. 45, 2116-2125.
    • (2008) Mol. Immunol. , vol.45 , pp. 2116-2125
    • Reimer, J.M.1    Enoksson, M.2    Samollow, P.B.3    Hellman, L.4
  • 65
    • 0025864033 scopus 로고
    • Mast cell tryptase is a mitogen for cultured fibroblasts
    • Ruoss S.J., Hartmann T. and Caughey G.H. (1991). Mast cell tryptase is a mitogen for cultured fibroblasts. J. Clin. Invest. 88, 493-499.
    • (1991) J. Clin. Invest. , vol.88 , pp. 493-499
    • Ruoss, S.J.1    Hartmann, T.2    Caughey, G.H.3
  • 66
    • 2942519841 scopus 로고    scopus 로고
    • A specific chymase inhibitor, NK3201, suppresses bleomycin-induced pulmonary fibrosis in hamsters
    • Sakaguchi M., Takai S., Jin D., Okamoto Y., Muramatsu M., Kim S. and Miyazaki M. (2004). A specific chymase inhibitor, NK3201, suppresses bleomycin-induced pulmonary fibrosis in hamsters. Eur. J. Pharmacol. 493, 173-176.
    • (2004) Eur. J. Pharmacol. , vol.493 , pp. 173-176
    • Sakaguchi, M.1    Takai, S.2    Jin, D.3    Okamoto, Y.4    Muramatsu, M.5    Kim, S.6    Miyazaki, M.7
  • 68
    • 0031065214 scopus 로고    scopus 로고
    • Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: Possible involvement of proinflammatory cytokines
    • Saleh D., Furukawa K., Tsao M.S., Maghazachi A., Corrin B., Yanagisawa M., Barnes P.J. and Giaid A. (1997). Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines. Am. J. Respir. Cell Mol. Biol. 16, 187-193.
    • (1997) Am. J. Respir. Cell Mol. Biol. , vol.16 , pp. 187-193
    • Saleh, D.1    Furukawa, K.2    Tsao, M.S.3    Maghazachi, A.4    Corrin, B.5    Yanagisawa, M.6    Barnes, P.J.7    Giaid, A.8
  • 69
    • 0031025002 scopus 로고    scopus 로고
    • Distinct multisite synergistic interactions determine substrate specificities of human chymase and rat chymase-1 for angiotensin II formation and degradation
    • Sanker S., Chandrasekharan U.M., Wilk D., Glynias M.J., Karnik S.S. and Husain A. (1997). Distinct multisite synergistic interactions determine substrate specificities of human chymase and rat chymase-1 for angiotensin II formation and degradation. J. Biol. Chem. 272, 2963-2968.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2963-2968
    • Sanker, S.1    Chandrasekharan, U.M.2    Wilk, D.3    Glynias, M.J.4    Karnik, S.S.5    Husain, A.6
  • 71
    • 0032825924 scopus 로고    scopus 로고
    • Effect of endothelin-1 on alphasmooth muscle actin expression and on alveolar fibroblasts proliferation in interstitial lung diseases
    • Shahar I., Fireman E., Topilsky M., Grief J., Schwarz Y., Kivity S., Ben-Efraim S. and Spirer Z. (1999). Effect of endothelin-1 on alphasmooth muscle actin expression and on alveolar fibroblasts proliferation in interstitial lung diseases. Int. J. Immunopharmacol. 21, 759-775.
    • (1999) Int. J. Immunopharmacol. , vol.21 , pp. 759-775
    • Shahar, I.1    Fireman, E.2    Topilsky, M.3    Grief, J.4    Schwarz, Y.5    Kivity, S.6    Ben-Efraim, S.7    Spirer, Z.8
  • 76
    • 67651021460 scopus 로고    scopus 로고
    • Pathologic and radiologic differences between idiopathic and collagen vascular disease-related usual interstitial pneumonia
    • Song J.W., Do K.H., Kim M.Y., Jang S.J., Colby T.V. and Kim D.S. (2009). Pathologic and radiologic differences between idiopathic and collagen vascular disease-related usual interstitial pneumonia. Chest 136, 23-30.
    • (2009) Chest , vol.136 , pp. 23-30
    • Song, J.W.1    Do, K.H.2    Kim, M.Y.3    Jang, S.J.4    Colby, T.V.5    Kim, D.S.6
  • 78
    • 0037379925 scopus 로고    scopus 로고
    • A novel chymase inhibitor, 4-[1-([bis-(4-methyl-phenyl)-methyl]-carbamoyl)3-(2-ethoxybenzyl)-4-oxo-azetidin e-2-yloxy]-benzoic acid (BCEAB), suppressed cardiac fibrosis in cardiomyopathic hamsters
    • Takai S., Jin D., Sakaguchi M., Katayama S., Muramatsu M., Sakaguchi M., Matsumura E., Kim S. and Miyazaki M. (2003). A novel chymase inhibitor, 4-[1-([bis-(4-methyl-phenyl)-methyl]-carbamoyl)3-(2-ethoxybenzyl)-4-oxo-azetidin e-2-yloxy]-benzoic acid (BCEAB), suppressed cardiac fibrosis in cardiomyopathic hamsters. J. Pharmacol. Exp. Ther. 305, 17-23.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 17-23
    • Takai, S.1    Jin, D.2    Sakaguchi, M.3    Katayama, S.4    Muramatsu, M.5    Sakaguchi, M.6    Matsumura, E.7    Kim, S.8    Miyazaki, M.9
  • 79
    • 4644289087 scopus 로고    scopus 로고
    • Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis
    • Takai S., Jin D., Muramatsu M., Okamoto Y. and Miyazaki M. (2004). Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis. Eur. J. Pharmacol. 501, 1-8.
    • (2004) Eur. J. Pharmacol. , vol.501 , pp. 1-8
    • Takai, S.1    Jin, D.2    Muramatsu, M.3    Okamoto, Y.4    Miyazaki, M.5
  • 80
    • 15744388309 scopus 로고    scopus 로고
    • A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
    • Tchougounova E., Lundequist A., Fajardo I., Winberg J.O., Abrink M. and Pejler G. (2005). A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J. Biol. Chem. 280, 9291-9296.
    • (2005) J. Biol. Chem. , vol.280 , pp. 9291-9296
    • Tchougounova, E.1    Lundequist, A.2    Fajardo, I.3    Winberg, J.O.4    Abrink, M.5    Pejler, G.6
  • 82
    • 77249175436 scopus 로고    scopus 로고
    • Mast cell peptidases: Chameleons of innate immunity and host defense
    • Trivedi N.N. and Caughey G.H. (2010). Mast cell peptidases: chameleons of innate immunity and host defense. Am. J. Respir. Cell Mol. Biol. 42, 257-267.
    • (2010) Am. J. Respir. Cell Mol. Biol. , vol.42 , pp. 257-267
    • Trivedi, N.N.1    Caughey, G.H.2
  • 86
    • 0025598309 scopus 로고
    • Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart
    • Urata H., Kinoshita A., Misono K.S., Bumpus F.M. and Husain A. (1990). Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart. J. Biol. Chem. 265, 22348-22357.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22348-22357
    • Urata, H.1    Kinoshita, A.2    Misono, K.S.3    Bumpus, F.M.4    Husain, A.5
  • 88
    • 2942707649 scopus 로고    scopus 로고
    • Identification of spontaneous feline idiopathic pulmonary fibrosis: Morphology and ultrastructural evidence for a type II pneumocyte defect
    • Williams K., Malarkey D., Cohn L., Patrick D., Dye J. and Toews G. (2004). Identification of spontaneous feline idiopathic pulmonary fibrosis: morphology and ultrastructural evidence for a type II pneumocyte defect. Chest 125, 2278-2288.
    • (2004) Chest , vol.125 , pp. 2278-2288
    • Williams, K.1    Malarkey, D.2    Cohn, L.3    Patrick, D.4    Dye, J.5    Toews, G.6
  • 91
    • 70349659185 scopus 로고    scopus 로고
    • Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and-independent Smad pathways: The role of Smad3
    • Yang F., Chung A.C., Huang X.R. and Lan H.Y. (2009). Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and-independent Smad pathways: the role of Smad3. Hypertension 54, 877-884.
    • (2009) Hypertension , vol.54 , pp. 877-884
    • Yang, F.1    Chung, A.C.2    Huang, X.R.3    Lan, H.Y.4
  • 92
    • 0032825253 scopus 로고    scopus 로고
    • Mast cell tryptase does not alter matrix metalloproteinase expression in human dermal fibroblasts: Further evidence that proteolytically-active tryptase is a potent fibrogenic factor
    • Zhang J., Gruber B.L., Marchese M.J., Zucker S., Schwartz L.B. and Kew R.R. (1999). Mast cell tryptase does not alter matrix metalloproteinase expression in human dermal fibroblasts: further evidence that proteolytically-active tryptase is a potent fibrogenic factor. J. Cell. Physiol. 181, 312-318.
    • (1999) J. Cell. Physiol. , vol.181 , pp. 312-318
    • Zhang, J.1    Gruber, B.L.2    Marchese, M.J.3    Zucker, S.4    Schwartz, L.B.5    Kew, R.R.6


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