Chymase-dependent conversion of big endothelin-1 in the mouse in vivo

Journal of Pharmacology and Experimental Therapeutics

Volumn 328, Issue 2, 2009, Pages 540-548

  Simard, Elie ^a   Jin, Denan ^b   Takai, Shinji ^b   Miyazaki, Mizuo ^b   Brochu, Isabelle ^a   D'Orléans Juste, Pedro ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA [(PHOSPHONOMETHYL)AMINO] 3 DIBENZOFURANOPROPANOIC ACID; BIG ENDOTHELIN 1; CGS 35066; CHYMASE; CHYMASE 4; CHYMASE 5; CHYMOSTATIN; COUMARIN DERIVATIVE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN 1 [1-31]; ENDOTHELIN CONVERTING ENZYME INHIBITOR; ENDOTHELIN RECEPTOR; ISOENZYME; MEMBRANE METALLOENDOPEPTIDASE; MESSENGER RNA; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; SUCCINYLLEUCYLLEUCYLVALYLTYROSYL 7 AMINO 4 METHYLCOUMARIN; SUCCINYLVALYLPROLYLPHENYLALANINE; THIORPHAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; TISSUE DISTRIBUTION;

ANESTHESIA; ANIMALS; CHYMASES; ENDOTHELIN-1; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; SERINE ENDOPEPTIDASES;

EID: 59649085140     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.142992     Document Type: Article

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