Tuberculosis diagnosis using immunodominant, secreted antigens of Mycobacterium tuberculosis

Tuberculosis

Volumn 93, Issue 4, 2013, Pages 381-388

  Bekmurzayeva, Aliya ^a   Sypabekova, Marzhan ^a   Kanayeva, Damira ^a  

^a NAZARBAYEV UNIVERSITY   (Kazakhstan)

Author keywords

Tuberculosis diagnosis Mpt64 Esat6 Cfp10 Ag85 Biosensor

Indexed keywords

AG85 COMPLEX; BACTERIAL PROTEIN; CULTURE FILTRATE PROTEIN 10; ESAT6 PROTEIN; MPT64 PROTEIN; MYCOBACTERIUM ANTIGEN; UNCLASSIFIED DRUG;

BACTERIAL VIRULENCE; BIOSENSOR; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; MYCOBACTERIUM AFRICANUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATCH TEST; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SECRETION; REVIEW; TUBERCULIN TEST; TUBERCULOSIS;

ANTIGENS, BACTERIAL; BIOLOGICAL MARKERS; HUMANS; IMMUNOCHROMATOGRAPHY; IMMUNODOMINANT EPITOPES; INTERFERON-GAMMA RELEASE TESTS; MYCOBACTERIUM TUBERCULOSIS; SEROLOGIC TESTS; TUBERCULIN TEST; TUBERCULOSIS;

EID: 84878945554     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2013.03.003     Document Type: Review

References (85)

1. A. Brent, D. Mugo, R. Musyimi, A. Mutiso, S. Morpeth, M. Levin, and J. Scott Performance of the MGIT TBc identification test and meta-analysis of MPT64 assays for identification of the Mycobacterium tuberculosis complex in liquid culture J Clin Microbiol 49 2011 4343 4346 10.1128/JCM.05995-11
2. Y.F. Ngeow, Y.L. Wong, K.P. Ng, C.S. Ong, and W.W. Aung Rapid, cost-effective application of tibilia TB rapid test for culture confirmation of live and heat-killed Mycobacterium tuberculosis J Clin Microbiol 49 2011 2776 2777 10.1128/jcm.00711-11
3. S. Singh, and V.M. Katoch Commercial serological tests for the diagnosis of active tuberculosis in India: time for introspection Indian J Med Res 134 2011 583 587
4. S.C. Hong, J. Lee, H.-C. Shin, C.-M. Kim, J.Y. Park, K. Koh, H.-J. Kim, C.L. Chang, and J. Lee Clinical immunosensing of tuberculosis CFP-10 in patient urine by surface plasmon resonance spectroscopy Sens Actuators B Chem 160 2011 10.1016/j.snb.2011.10.006
5. S. Deng, T. Yuan, J. Xia, H. Huang, X. Cheng, and M. Chen Clinical utility of a combination of lipoarabinomannan, 38-kDa and 16-kDa antigens as a diagnosis tool for tuberculosis Diagn Microbiol Infect Dis 71 2011 46 50 10.1016/j.diagmicrobio.2011.04.015
6. FIND Diagnostics for tuberculosis global demand and market potential 2006
7. S.C. Hong, H. Chen, J. Lee, H.-K. Park, Y.S. Kim, H.-C. Shin, C.-M. Kim, T.J. Park, S.J. Lee, K. Koh, H.-J. Kim, C.L. Chang, and J. Lee Ultrasensitive immunosensing of tuberculosis CFP-10 based on SPR spectroscopy Sens Actuators B Chem 156 2011 10.1016/j.snb.2011.04.032
8. S.T. Cole, R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S.V. Gordon, K. Eiglmeier, S. Gas, C.E. Barry 3rd, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M.A. Quail, M.A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J.E. Sulston, K. Taylor, S. Whitehead, and B.G. Barrell Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence Nature 393 1998 537 544 10.1038/31159
9. A. Martin, D. Bombeeck, K. Fissette, P. de Rijk, I. Hernandez-Neuta, P. Del Portillo, and J.C. Palomino Evaluation of the BD MGIT TBc Identification Test (TBc ID), a rapid chromatographic immunoassay for the detection of Mycobacterium tuberculosis complex from liquid culture J Microbiol Methods 84 2011 255 257 10.1016/j.mimet.2010.12.003
10. P. Roche, N. Winter, J. Triccas, C. Feng, and W. Britton Expression of Mycobacterium tuberculosis MPT64 in recombinant Myco-smegmatis: purification, immunogenicity and application to skin tests for tuberculosis Clin Exp Immunol 103 1996 226 232 10.1046/j.1365-2249.1996.d01-613.x
11. D. Chaves, A. Sandoval, L. Rodriguez, J.C. Garcia, S. Restrepo, and M. Mercedes Zambrano Comparative analysis of six Mycobacterium tuberculosis complex genomes Biomedica 30 2010 23 31
12. C. Abe, K. Hirano, and T. Tomiyama Simple and rapid identification of the Mycobacterium tuberculosis complex by immunochromatographic assay using anti-MPB64 monoclonal antibodies J Clin Microbiol 37 1999 3693 3697
13. M.A. Behr BCG - different strains, different vaccines? Lancet Infect Dis 2 2002 86 92 10.1016/s1473-3099(02)00182-2
14. Z. Wang, B.M. Potter, A.M. Gray, K.A. Sacksteder, B.V. Geisbrecht, and J.H. Laity The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a new family of beta-grasp proteins J Mol Biol 366 2007 375 381 10.1016/j.jmb.2006.11.039
15. K. Weldingh, and P. Andersen Immunological evaluation of novel Mycobacterium tuberculosis culture filtrate proteins FEMS Immunol Med Microbiol 23 1999 159 164 10.1111/j.1574-695X.1999.tb01235.x
16. R. Kozak, and M.A. Behr Divergence of immunologic and protective responses of different BCG strains in a murine model Vaccine 29 2011 1519 1526 10.1016/j.vaccine.2010.12.012
17. M.A. Behr, M.A. Wilson, W.P. Gill, H. Salamon, G.K. Schoolnik, S. Rane, and P.M. Small Comparative genomics of BCG vaccines by whole-genome DNA microarray Science 284 1999 1520 1523 10.1126/science.284.5419.1520
18. Protein Data Bank R. 2HHI literature report; 2012.
19. T.-P.J. Chu, and J.-M.P. Yuann Expression, purification, and characterization of protective MPT64 antigen protein and identification of its multimers isolated from nontoxic Mycobacterium tuberculosis H37Ra Biotechnol Appl Biochem 58 2011 185 189 10.1002/bab.26
20. T. Gaillard, M. Fabre, C. Martinaud, R. Vong, P. Brisou, and C. Soler Assessment of the SD Bioline Ag MPT64 Rapid (TM) and the MGIT (TM) TBc identification tests for the diagnosis of tuberculosis Diagn Microbiol Infect Dis 70 2011 154 156 10.1016/j.diagmicrobio.2010.12.011
21. V.G. Kumar, T.A. Urs, and R.R. Ranganath MPT 64 Antigen detection for Rapid confirmation of M. tuberculosis isolates BMC Res Notes 4 2011 79
22. Z. Liu, C. Zhu, H. Yang, H. Hu, Y. Feng, L. Qin, Z. Cui, A. Bi, R. Zheng, R. Jin, L. Fan, and Z. Hu Clinical value of ELISA-MPT64 for the diagnosis of tuberculous pleurisy Curr Microbiol 65 2012 313 318
23. Z. Wang, B. Potter, A. Gray, K. Sacksteder, B. Geisbrecht, and J. Laity The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a new family of beta-grasp proteins J Mol Biol 366 2007 375 381 10.1016/j.jmb.2006.11.039
24. P. Roche, C. Feng, and W. Britton Human T-cell epitopes on the Mycobacterium tuberculosis secreted protein MPT64 Scand J Immunol 43 1996 662 670 10.1046/j.1365-3083.1996.d01-260.x
25. Y. Bai, Y. Xue, H. Gao, L. Wang, T. Ding, W. Bai, A. Fan, H. Zhang, Q. An, and Z. Xu Expression and purification of Mycobacterium tuberculosis ESAT-6 and MPT64 fusion protein and its immunoprophylactic potential in mouse model Protein Expr Purif 59 2008 189 196 10.1016/j.pep.2007.11.016
26. P. Brodin, I. Rosenkrands, P. Andersen, S.T. Cole, and R. Brosch ESAT-6 proteins: protective antigens and virulence factors? Trends Microbiol 12 2004 500 508 10.1016/j.tim.2004.09.007
27. Q. Wang, C. Lei, H. Wan, and Q. Liu Improved cellular immune response elicited by a ubiquitin-fused DNA vaccine against Mycobacterium tuberculosis DNA Cell Biol 31 2012 489 495 10.1089/dna.2011.1309
28. L.A.H. van Pinxteren, P. Ravn, E.M. Agger, J. Pollock, and P. Andersen Diagnosis of tuberculosis based on the two specific antigens ESAT-6 and CFP10 Clin Diagn Lab Immunol 7 2000 155 160
29. J.-W. Chen, S.M. Faisal, S. Chandra, S.P. McDonough, M.A.S. Moreira, J. Scaria, C.-F. Chang, J.P. Bannantine, B. Akey, and Y.-F. Chang Immunogenicity and protective efficacy of the Mycobacterium avium subsp. paratuberculosis attenuated mutants against challenge in a mouse model 30 2012 3015 3025 10.1016/j.vaccine.2011.11.029
30. X. Tang, W. Deng, and J. Xie Novel insights into Mycobacterium antigen Ag85 biology and implications in countermeasures for M. tuberculosis Crit Rev Eukaryot Gene Expr 2012 179 187 United States
31. S.L. Baldwin, C.D. D'Souza, I.M. Orme, M.A. Liu, K. Huygen, O. Denis, A. Tang, L. Zhu, D. Montgomery, and J.B. Ulmer Immunogenicity and protective efficacy of DNA vaccines encoding secreted and non-secreted forms of Mycobacterium tuberculosis Ag85A Tuber Lung Dis 1999 251 259 Scotland
32. J.A. Langermans, T.M. Doherty, R.A. Vervenne, T. van der Laan, K. Lyashchenko, R. Greenwald, E.M. Agger, C. Aagaard, H. Weiler, D. van Soolingen, W. Dalemans, A.W. Thomas, and P. Andersen Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6 Vaccine 2005 2740 2750 Netherlands
33. D.R. Ronning, T. Klabunde, G.S. Besra, V.D. Vissa, J.T. Belisle, and J.C. Sacchettini Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines Nat Struct Biol 7 2000 141 146 10.1038/72413
34. D.H. Anderson, G. Harth, M.A. Horwitz, and D. Eisenberg An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase J Mol Biol 2001 671 681 Academic Press, England
35. S.I. Bentley-Hibbert, X. Quan, T. Newman, K. Huygen, and H.P. Godfrey Pathophysiology of antigen 85 in patients with active tuberculosis: antigen 85 circulates as complexes with fibronectin and immunoglobulin G Infect Immun 67 1999 581 588
36. D.R. Ronning, V. Vissa, G.S. Besra, J.T. Belisle, and J.C. Sacchettini Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity J Biol Chem 2004 10.1074/jbc.M400811200
37. L.Y. Armitige, C. Jagannath, A.R. Wanger, and S.J. Norris Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: effect on growth in culture and in macrophages Infect Immun 68 2000 767 778
38. J.T. Belisle, V.D. Vissa, T. Sievert, K. Takayama, P.J. Brennan, and G.S. Besra Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis Science 276 1997 1420 1422
39. Y.H. Nguyen, X. Ma, and L. Qin Rapid identification and drug susceptibility screening of ESAT-6 secreting Mycobacteria by a NanoELIwell assay Sci Rep 2 2012 10.1038/srep00635
40. P.S. Renshaw, K.L. Lightbody, V. Veverka, F.W. Muskett, G. Kelly, T.A. Frenkiel, S.V. Gordon, R.G. Hewinson, B. Burke, J. Norman, R.A. Williamson, and M.D. Carr Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6 EMBO J 24 2005 2491 2498 10.1038/sj.emboj.7600732
41. K.L. Lightbody, D. Ilghari, L.C. Waters, G. Carey, M.A. Bailey, R.A. Williamson, P.S. Renshaw, and M.D. Carr Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins J Biol Chem 283 2008 17681 17690 10.1074/jbc.M800123200
42. L. Majlessi, P. Brodin, R. Brosch, M.J. Rojas, H. Khun, M. Huerre, S.T. Cole, and C. Leclerc Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system J Immunol 174 2005 3570 3579
43. A. Raja, U.D. Ranganathan, and R. Bethunaickan Improved diagnosis of pulmonary tuberculosis by detection of antibodies against multiple Mycobacterium tuberculosis antigens Diagn Microbiol Infect Dis 60 2008 361 368 10.1016/j.diagmicrobio.2007.11.006
44. H. Niu, L. Hu, Q. Li, Z. Da, B. Wang, K. Tang, Q. Xin, H. Yu, Y. Zhang, Y. Wang, X. Ma, and B. Zhu Construction and evaluation of a multistage Mycobacterium tuberculosis subunit vaccine candidate Mtb10.4-HspX Vaccine 29 2011 9451 9458 10.1016/j.vaccine.2011.10.032
45. N.A. Parlane, B.J. Compton, C.M. Hayman, G.F. Painter, R.J. Basaraba, A. Heiser, and B.M. Buddle Phosphatidylinositol di-mannoside and derivates modulate the immune response to and efficacy of a tuberculosis protein vaccine against Mycobacterium bovis infection Vaccine 30 2012 580 588 10.1016/j.vaccine.2011.11. 055
46. S.B. Sable, I. Verma, and G.K. Khuller Multicomponent antituberculous subunit vaccine based on immunodominant antigens of Mycobacterium tuberculosis Vaccine 23 2005 4175 4184 10.1016/j.vaccine.2005.03.040
47. J. Lighter, and M. Rigaud Diagnosing childhood tuberculosis: traditional and innovative modalities Curr Probl Pediatr Adolesc Health Care 39 2009 61 88
48. FIND New laboratory diagnostic tools for tuberculosis control 2012
49. S. Chaudhary, S. Gupta, S. Khare, and S. Lal Diagnosis of tuberculosis in an era of HIV pandemic: a review of current status and future prospects 28 2010 281 289
50. M. Pai, J. Minion, K. Steingart, and A. Ramsay New and improved tuberculosis diagnostics: evidence, policy, practice, and impact Curr Opin Pulm Med 16 2010 271 284 10.1097/MCP.0b013e328338094f
51. V.I. Kiselev, P.M. Baranovskii, I.V. Rudykh, A.M. Shuster, V.A. Mart'ianov, B.L. Mednikov, A.V. Demin, A.N. Aleksandrov, A.I. Mushkin, D.T. Levi, L.V. Slogotskaia, E.S. Ovsiankina, N.V. Medunitsin, V.I. Litvinov, M.I. Perel'man, and M.A. Pal'tsev Clinical trials of the new skin test Diaskintest for the diagnosis of tuberculosis Probl Tuberk Bolezn Legk 2009 11 16
52. M. Malaghini, V. Thomaz-Soccol, C.M. Probst, M.A. Krieger, H. Preti, A. Kritski, and C.R. Soccol Recombinant antigen production for assays of intradermoreaction for diagnosis and surveillance of tuberculosis J Biotechnol 156 2011 56 58 10.1016/j.jbiotec.2011.07.015
53. Method and apparatus for relating datasets by using semantic vectors and keyword analyses 2011 IP.com
54. L.M. Parsons, A. Somoskoevi, C. Gutierrez, E. Lee, C.N. Paramasivan, Abimiku Al, S. Spector, G. Roscigno, and J. Nkengasong Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities Clin Microbiol Rev 24 2011 314 10.1128/cmr.00059-10
55. G.-H. Shen, C.-S. Chiou, S.-T. Hu, K.-M. Wu, and J.-H. Chen Rapid identification of the Mycobacterium tuberculosis complex by combining the ESAT-6/CFP-10 immunochromatographic assay and smear morphology J Clin Microbiol 49 2011 902 907 10.1128/jcm.00592-10
56. C.-M. Fan, W. Li, D.-L. Fan, X.-Y. Zheng, and J.-Z. Ding A study of double antigen sandwich colloidal gold immunochromatography rapid detection for Mycobacterium tuberculosis antibody Chin J Tuberc Respir Dis 34 2011 356 358
57. R.A. Cole, H.M. Lu, Y.Z. Shi, J. Wang, T. De-Hua, and A.T. Zhou Clinical evaluation of a rapid immunochromatographic assay based on the 38 kDa antigen of Mycobacterium tuberculosis on patients with pulmonary tuberculosis in China Tuber Lung Dis 1996 363 368 Scotland
58. J.A. Ramos-Vara Technical aspects of immunohistochemistry Vet Pathol 42 2005 405 426 10.1354/vp.42-4-405
59. M. Purohit, T. Mustafa, H. Wiker, O. Morkve, and L. Sviland Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64 Diagn Pathol 2 2007 10.1186/1746-1596-2-36
60. K. Baba, A. Dyrhol-Riise, L. Sviland, N. Langeland, A. Hoosen, H. Wiker, and T. Mustafa Rapid and specific diagnosis of tuberculous pleuritis with immunohistochemistry by detecting Mycobacterium tuberculosis complex specific antigen MPT64 in patients from a HIV endemic area Appl Immunohistochem Mol Morphol 16 2008 554 561 10.1097/PAI.0b013e31816c3f79
61. S. Sumi, and V. Radhakrishnan Evaluation of immunohistochemistry with a panel of antibodies against recombinant mycobacterial antigens for the diagnosis of tuberculous lymphadenitis Int J Med Med Sci 1 2009 215 219
62. T. Mustafa, H.G. Wiker, S.G.M. Mfinanga, O. Morkve, and L. Sviland Immunohistochemistry using a Mycobacterium tuberculosis complex specific antibody for improved diagnosis of tuberculous lymphadenitis Mod Pathol 19 2006 1606 1614 10.1038/modpathol.3800697
63. Z.-H. Liu, L.-H. Qin, Y.-H. Feng, A.-X. Bi, H. Yang, Y.-S. Ding, Z.-L. Cui, R.-L. Jin, R.-J. Zheng, and Z.-Y. Hu Identification of the Mycobacterium tuberculosis complex by detecting recombinant secretory protein MPT64 Chin J Tuber Respir Dis 32 2009 608 612
64. R. Dayal, A. Singh, V.M. Katoch, B. Joshi, D.S. Chauhan, P. Singh, G. Kumar, and V.D. Sharma Serological diagnosis of tuberculosis Indian J Pediatr 75 2008 1219 1221 10.1007/s12098-008-0222-3
65. G. Kumar, P.K. Dagur, M. Singh, V.S. Yadav, R. Dayal, H.B. Singh, V.M. Katoch, U. Sengupta, and B. Joshi Diagnostic potential of Ag85C in comparison to various secretory antigens for childhood tuberculosis Scand J Immunol 2008 177 183 England
66. R. Singh, P. Toor, S. Parchand, K. Sharma, V. Gupta, and A. Gupta Quantitative polymerase chain reaction for Mycobacterium tuberculosis in so-called Eales' disease Ocul Immunol Inflamm 20 2012 153 157 10.3109/09273948.2012.658134
67. S. Sethi, R. Yadav, A. Mewara, S.K. Dhatwalia, M. Sharma, and D. Gupta Evaluation of in-house mpt64 real-time PCR for rapid detection of Mycobacterium tuberculosis in pulmonary and extra-pulmonary specimens Braz J Infect Dis 16 2012 493 494 10.1016/j.bjid.2012.08.010
68. K. Sharma, A. Sharma, S.K. Sharma, R.K. Sen, M.S. Dhillon, and M. Sharma Does multiplex polymerase chain reaction increase the diagnostic percentage in osteoarticular tuberculosis? A prospective evaluation of 80 cases Int Orthopaed 36 2012 255 259 10.1007/s00264-011-1241-7
69. V. Vadwai, A. Shetty, and C. Rodrigues Using likelihood ratios to estimate diagnostic accuracy of a novel multiplex nested PCR in extra-pulmonary tuberculosis Int J Tuberc Lung Dis 16 2012 240 247 10.5588/ijtld.11.0322
70. A. Dil, A.W. Mir, A. Kirmani, R. Shakeel ul, R. Eachkoti, and M.A. Siddiqi Improved diagnosis of central nervous system tuberculosis by MPB64-target PCR Braz J Microbiol 39 2008 209 213 10.1590/s1517- 83822008000200002
71. M. Fauville-Dufaux, A. Waelbroeck, P. De Mol, B. Vanfleteren, J. Levy, P. Debusschere, and C.M. Farber Contribution of the polymerase chain reaction to the diagnosis of tuberculous infections in children Eur J Pediatr 155 1996 106 111
72. M. Pai, L.W. Riley, and J.M. Colford Interferonn assays-gamma in the immunodiagnosis of tuberculosis: a systematic review Lancet Infect Dis 4 2004 761 776 10.1016/s1473-3099(04)01206-x
73. J. Chen, X. Su, Y. Zhang, S. Wang, L. Shao, J. Wu, F. Wang, S. Zhang, J. Wang, X. Weng, H. Wang, and W. Zhang Novel recombinant RD2-and RD11-encoded Mycobacterium tuberculosis antigens are potential candidates for diagnosis of tuberculosis infections in BCG-vaccinated individuals Microbes Infect 11 2009 876 885 10.1016/j.micinf.2009.05.008
74. J. Bautista, and N. Banaei Sensitivity of QuantiFERON-TB GOLD In-Tube for diagnosis of recent versus remote M. tuberculosis infection Diagn Microbiol Infect Dis 73 2012 257 259 10.1016/j.diagmicrobio.2012.03.018
75. J.C. Cooper, and E.A.H. Hall The nature of biosensor technology J Biomed Eng 10 1988 210 219 10.1016/0141-5425(88)90001-5
76. Y. Wang, and B. Liu Conjugated polyelectrolyte-sensitized fluorescent detection of thrombin in blood serum using aptamer-immobilized silica nanoparticles as the platform Langmuir 25 2009 12787 12793 10.1021/la901703p
77. S.-E. Kim, K.-Y. Ahn, J.-S. Park, K.R. Kim, K.E. Lee, S.-S. Han, and J. Lee Fluorescent ferritin nanoparticles and application to the aptamer sensor Anal Chem 83 2011 5834 5843 10.1021/ac200657s
78. L. Qin, R. Zheng, Z. Ma, Y. Feng, Z. Liu, H. Yang, J. Wang, R. Jin, J. Lu, Y. Ding, and Z. Hu The selection and application of ssDNA aptamers against MPT64 protein in Mycobacterium tuberculosis Clin Chem Lab Med 47 2009 405 411 10.1515/CCLM.2009.097
79. H. Mukundan, S. Kumar, D.N. Price, S.M. Ray, Y.J. Lee, S. Min, S. Eum, J. Kubicek-Sutherland, J.M. Resnick, W.K. Grace, A.S. Anderson, S.H. Hwang, S.N. Cho, L.E. Via, C. Barry 3rd, R. Sakamuri, and B.I. Swanson Rapid detection of Mycobacterium tuberculosis biomarkers in a sandwich immunoassay format using a waveguide-based optical biosensor Tuberculosis (Edinb) 92 2012 407 416 10.1016/j.tube.2012.05.009
80. J.L.V. Seong Cheol Hong, Hyun-Chul Shin, Cheol-Min Kim, Jung Youn Park, Kwangnak Koh, Hwa-Jung Kim, Chulhun L. Chang, and Jaebeom Lee Clinical immunosensing of tuberculosis CFP-10 in patient urine by surface plasmon resonance spectroscopy 160 2011 1434 1438 10.1016/j.snb.2011.10.006
81. Namba Y, Yasuharu NJP. Method for detecting Mycobacterium tuberculosis, involves performing immunoassay using antibody with respect to epitope of Mycobacterium tuberculosis specific secreted protein MPB64. Bl Co Ltd.
82. A.J. Brent, D. Mugo, R. Musyimi, A. Mutiso, S. Morpeth, M. Levin, and J.A.G. Scott Performance of the MGIT TBc identification test and meta-analysis of MPT64 assays for identification of the Mycobacterium tuberculosis complex in liquid culture J Clin Microbiol 49 2011 4343 4346 10.1128/jcm.05995-11
83. P. Andersen, T.M. Doherty, M. Pai, and K. Weldingh The prognosis of latent tuberculosis: can disease be predicted Trends Mol Med 13 2007 175 182 10.1016/j.molmed.2007.03.004
84. L.H. Qin, R.J. Zheng, Z.X. Ma, Y.H. Feng, Z.H. Liu, H. Yang, J. Wang, R.L. Jin, J.M. Lu, Y.S. Ding, and Z.Y. Hu The selection and application of ssDNA aptamers against MPT64 protein in Mycobacterium tuberculosis Clin Chem Lab Med 47 2009 405 411 10.1515/cclm.2009.097
85. C. Zhu, J. Liu, Y. Ling, H. Yang, Z. Liu, R. Zheng, L. Qin, and Z. Hu Evaluation of the clinical value of ELISA based on MPT64 antibody aptamer for serological diagnosis of pulmonary tuberculosis BMC Infect Dis 2012 96