Phosphatidylinositol di-mannoside and derivates modulate the immune response to and efficacy of a tuberculosis protein vaccine against Mycobacterium bovis infection

Vaccine

Volumn 30, Issue 3, 2012, Pages 580-588

  Parlane, Natalie A ^a   Compton, Benjamin J ^b   Hayman, Colin M ^b   Painter, Gavin F ^b   Basaraba, Randall J ^c   Heiser, Axel ^a   Buddle, Bryce M ^a  

^a AGRESEARCH GRASSLANDS   (New Zealand)

^b CALLAGHAN INNOVATION   (New Zealand)

^c Veterinary Dentistry and Oral Surgery   (United States)

Author keywords

Cattle; Mycobacterium bovis; Phosphatidylinositol mannoside; Tuberculosis; Vaccine

Indexed keywords

AG85A ESAT 6 PROTEIN; BACTERIAL PROTEIN; BCG VACCINE; GAMMA INTERFERON; GLYCOLIPID; PHOSPHATIDYLGLYCEROL DI MANNOSIDE; PHOSPHATIDYLINOSITOL DI MANNOSIDE; TUBERCULOSIS PROTEIN VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL COUNT; BOVINE TUBERCULOSIS; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RESPONSE; DRUG EFFICACY; DRUG POTENCY; FEMALE; IMMUNOMODULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TH1 CELL;

ACYLTRANSFERASES; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL LOAD; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; LUNG; MICE; MICE, INBRED C57BL; MYCOBACTERIUM BOVIS; PHOSPHATIDYLINOSITOLS; TH1 CELLS; TUBERCULOSIS; TUBERCULOSIS VACCINES; VACCINES, SUBUNIT;

EID: 84355166213     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.11.055     Document Type: Article

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