Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines

Nature Structural Biology

Volumn 7, Issue 2, 2000, Pages 141-146

  Running, Donald R ^a   Klabunde, Thomas ^a   Besra, Gurdyal S ^b   Vissa, Varalakshmi D ^c   Belisle, John I ^c   Sacchettini, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIMYCOBACTERIAL AGENT; BACTERIAL ANTIGEN; BCG VACCINE; CORD FACTOR; ETHAMBUTOL; FIBRONECTIN; ISONIAZID; MYCOLIC ACID;

AMINO ACID SEQUENCE; ANTIGENICITY; ARTICLE; BACTERIAL CELL WALL; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; PROTEIN FOLDING; STRUCTURE ANALYSIS;

ACYLTRANSFERASES; AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; ANTITUBERCULAR AGENTS; BINDING SITES; CATALYTIC DOMAIN; CELL WALL; CORD FACTORS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; FIBRONECTINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PHOSPHORIC ACID ESTERS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0033960935     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/72413     Document Type: Article

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