An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (antigen 85B), a mycolyl transferase

Journal of Molecular Biology

Volumn 307, Issue 2, 2001, Pages 671-681

  Anderson, Daniel H ^a   Harth, Günter ^b   Horwitz, Marcus A ^b   Eisenberg, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

30 kDa major secretory protein; Antigen 85B; Drug design; Mycobacterium tuberculosis; Mycolyl transferase

Indexed keywords

BACTERIAL PROTEIN; MYCOBACTERIUM ANTIGEN; MYCOLYL TRANSFERASE; SECRETORY PROTEIN; TREHALOSE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG TARGETING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN STRUCTURE; TUBERCULOSIS; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0035937258     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4461     Document Type: Article

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