메뉴 건너뛰기




Volumn 29, Issue 51, 2011, Pages 9451-9458

Construction and evaluation of a multistage Mycobacterium tuberculosis subunit vaccine candidate Mtb10.4-HspX

Author keywords

HspX; Mtb10.4; Multi stage vaccine; Mycobacterium tuberculosis; Subunit vaccine

Indexed keywords

BCG VACCINE; CORD FACTOR; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; PROTEIN MTB10.4 HSPX; SUBUNIT VACCINE; UNCLASSIFIED DRUG;

EID: 81955164734     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.10.032     Document Type: Article
Times cited : (63)

References (48)
  • 2
    • 33846677166 scopus 로고    scopus 로고
    • Epidemiology of tuberculosis in a high HIV prevalence population provided with enhanced diagnosis of symptomatic disease
    • Corbett E.L., Bandason T., Cheung Y.B., Munyati S., Godfrey-Faussett P., Hayes R., et al. Epidemiology of tuberculosis in a high HIV prevalence population provided with enhanced diagnosis of symptomatic disease. PLoS Med 2007, 4:e22.
    • (2007) PLoS Med , vol.4
    • Corbett, E.L.1    Bandason, T.2    Cheung, Y.B.3    Munyati, S.4    Godfrey-Faussett, P.5    Hayes, R.6
  • 3
    • 77950313157 scopus 로고    scopus 로고
    • Multidrug-resistant tuberculosis: epidemiology, risk factors and case finding
    • Caminero J.A. Multidrug-resistant tuberculosis: epidemiology, risk factors and case finding. Int J Tuberc Lung Dis 2010, 14:382-390.
    • (2010) Int J Tuberc Lung Dis , vol.14 , pp. 382-390
    • Caminero, J.A.1
  • 4
    • 79955103273 scopus 로고    scopus 로고
    • Available from: World Health Organization
    • World Health Organization Global tuberculosis control 2010, Available from: http://www.who.int/tb/publications/global_report/2010/en/index.html.
    • (2010) Global tuberculosis control
  • 5
    • 33845917536 scopus 로고    scopus 로고
    • Vaccine strategies against latent tuberculosis infection
    • Andersen P. Vaccine strategies against latent tuberculosis infection. Trends Microbiol 2007, 15:7-13.
    • (2007) Trends Microbiol , vol.15 , pp. 7-13
    • Andersen, P.1
  • 6
    • 0035235942 scopus 로고    scopus 로고
    • The global tuberculosis situation and the new control strategy of the World Health Organization, 1991
    • Kochi A. The global tuberculosis situation and the new control strategy of the World Health Organization, 1991. Bull World Health Organ 2001, 79:71-75.
    • (2001) Bull World Health Organ , vol.79 , pp. 71-75
    • Kochi, A.1
  • 7
    • 32944466277 scopus 로고    scopus 로고
    • The development and impact of tuberculosis vaccines
    • Young D., Dye C. The development and impact of tuberculosis vaccines. Cell 2006, 124:683-687.
    • (2006) Cell , vol.124 , pp. 683-687
    • Young, D.1    Dye, C.2
  • 8
    • 0028872014 scopus 로고
    • Variation in protection by BCG: implications of and for heterologous immunity
    • Fine P.E. Variation in protection by BCG: implications of and for heterologous immunity. Lancet 1995, 346:1339-1345.
    • (1995) Lancet , vol.346 , pp. 1339-1345
    • Fine, P.E.1
  • 9
    • 0023937061 scopus 로고
    • BCG vaccination against tuberculosis and leprosy
    • Fine P.E. BCG vaccination against tuberculosis and leprosy. Br Med Bull 1988, 44:691-703.
    • (1988) Br Med Bull , vol.44 , pp. 691-703
    • Fine, P.E.1
  • 10
    • 0034610299 scopus 로고    scopus 로고
    • Recombinant bacillus Calmette-Guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model
    • Horwitz M.A., Harth G., Dillon B.J., Maslesa-Galic S. Recombinant bacillus Calmette-Guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model. Proc Natl Acad Sci USA 2000, 97:13853-13858.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13853-13858
    • Horwitz, M.A.1    Harth, G.2    Dillon, B.J.3    Maslesa-Galic, S.4
  • 11
    • 22344433382 scopus 로고    scopus 로고
    • Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin
    • Grode L., Seiler P., Baumann S., Hess J., Brinkmann V., Nasser Eddine A., et al. Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin. J Clin Invest 2005, 115:2472-2479.
    • (2005) J Clin Invest , vol.115 , pp. 2472-2479
    • Grode, L.1    Seiler, P.2    Baumann, S.3    Hess, J.4    Brinkmann, V.5    Nasser Eddine, A.6
  • 12
    • 33645314357 scopus 로고    scopus 로고
    • The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs
    • Martin C., Williams A., Hernandez-Pando R., Cardona P.J., Gormley E., Bordat Y., et al. The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs. Vaccine 2006, 24(24):3408-3419.
    • (2006) Vaccine , vol.24 , Issue.24 , pp. 3408-3419
    • Martin, C.1    Williams, A.2    Hernandez-Pando, R.3    Cardona, P.J.4    Gormley, E.5    Bordat, Y.6
  • 13
    • 12844272269 scopus 로고    scopus 로고
    • Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis
    • Sambandamurthy V.K., Derrick S.C., Jalapathy K.V., Chen B., Russell R.G., Morris S.L., et al. Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis. Infect Immun 2005, 73:1196-1203.
    • (2005) Infect Immun , vol.73 , pp. 1196-1203
    • Sambandamurthy, V.K.1    Derrick, S.C.2    Jalapathy, K.V.3    Chen, B.4    Russell, R.G.5    Morris, S.L.6
  • 14
    • 65349186494 scopus 로고    scopus 로고
    • MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques
    • Verreck F.A., Vervenne R.A., Kondova I., van Kralingen K.W., Remarque E.J., Braskamp G., et al. MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques. PLoS One 2009, 4:e5264.
    • (2009) PLoS One , vol.4
    • Verreck, F.A.1    Vervenne, R.A.2    Kondova, I.3    van Kralingen, K.W.4    Remarque, E.J.5    Braskamp, G.6
  • 15
    • 56849108004 scopus 로고    scopus 로고
    • RBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector
    • Magalhaes I., Sizemore D.R., Ahmed R.K., Mueller S., Wehlin L., Scanga C., et al. rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector. PLoS One 2008, 3:e3790.
    • (2008) PLoS One , vol.3
    • Magalhaes, I.1    Sizemore, D.R.2    Ahmed, R.K.3    Mueller, S.4    Wehlin, L.5    Scanga, C.6
  • 16
    • 0035055282 scopus 로고    scopus 로고
    • Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and ESAT-6
    • Weinrich Olsen A., van Pinxteren L.A., Meng Okkels L., Birk Rasmussen P., Andersen P. Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and ESAT-6. Infect Immun 2001, 69:2773-2778.
    • (2001) Infect Immun , vol.69 , pp. 2773-2778
    • Weinrich Olsen, A.1    van Pinxteren, L.A.2    Meng Okkels, L.3    Birk Rasmussen, P.4    Andersen, P.5
  • 17
    • 18644373991 scopus 로고    scopus 로고
    • Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy
    • Dietrich J., Aagaard C., Leah R., Olsen A.W., Stryhn A., Doherty T.M., et al. Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy. J Immunol 2005, 174:6332-6339.
    • (2005) J Immunol , vol.174 , pp. 6332-6339
    • Dietrich, J.1    Aagaard, C.2    Leah, R.3    Olsen, A.W.4    Stryhn, A.5    Doherty, T.M.6
  • 18
    • 2942596008 scopus 로고    scopus 로고
    • Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein
    • Skeiky Y.A., Alderson M.R., Ovendale P.J., Guderian J.A., Brandt L., Dillon D.C., et al. Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein. J Immunol 2004, 172:7618-7628.
    • (2004) J Immunol , vol.172 , pp. 7618-7628
    • Skeiky, Y.A.1    Alderson, M.R.2    Ovendale, P.J.3    Guderian, J.A.4    Brandt, L.5    Dillon, D.C.6
  • 19
    • 34249882752 scopus 로고    scopus 로고
    • T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination
    • Geluk A., Lin M.Y., van Meijgaarden K.E., Leyten E.M., Franken K.L., Ottenhoff T.H., et al. T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination. Infect Immun 2007, 75:2914-2921.
    • (2007) Infect Immun , vol.75 , pp. 2914-2921
    • Geluk, A.1    Lin, M.Y.2    van Meijgaarden, K.E.3    Leyten, E.M.4    Franken, K.L.5    Ottenhoff, T.H.6
  • 20
    • 0033966029 scopus 로고    scopus 로고
    • Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens
    • Skjot R.L., Oettinger T., Rosenkrands I., Ravn P., Brock I., Jacobsen S., et al. Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens. Infect Immun 2000, 68:214-220.
    • (2000) Infect Immun , vol.68 , pp. 214-220
    • Skjot, R.L.1    Oettinger, T.2    Rosenkrands, I.3    Ravn, P.4    Brock, I.5    Jacobsen, S.6
  • 21
    • 4644235020 scopus 로고    scopus 로고
    • Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model
    • Olsen A.W., Williams A., Okkels L.M., Hatch G., Andersen P. Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model. Infect Immun 2004, 72:6148-6150.
    • (2004) Infect Immun , vol.72 , pp. 6148-6150
    • Olsen, A.W.1    Williams, A.2    Okkels, L.M.3    Hatch, G.4    Andersen, P.5
  • 22
    • 20144362100 scopus 로고    scopus 로고
    • Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6
    • Langermans J.A., Doherty T.M., Vervenne R.A., van der Laan T., Lyashchenko K., Greenwald R., et al. Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6. Vaccine 2005, 23:2740-2750.
    • (2005) Vaccine , vol.23 , pp. 2740-2750
    • Langermans, J.A.1    Doherty, T.M.2    Vervenne, R.A.3    van der Laan, T.4    Lyashchenko, K.5    Greenwald, R.6
  • 23
    • 0036784680 scopus 로고    scopus 로고
    • Epitope mapping of the immunodominant antigen TB10.4 and the two homologous proteins TB10.3 and TB12.9, which constitute a subfamily of the esat-6 gene family
    • Skjot R.L., Brock I., Arend S.M., Munk M.E., Theisen M., Ottenhoff T.H., et al. Epitope mapping of the immunodominant antigen TB10.4 and the two homologous proteins TB10.3 and TB12.9, which constitute a subfamily of the esat-6 gene family. Infect Immun 2002, 70:5446-5453.
    • (2002) Infect Immun , vol.70 , pp. 5446-5453
    • Skjot, R.L.1    Brock, I.2    Arend, S.M.3    Munk, M.E.4    Theisen, M.5    Ottenhoff, T.H.6
  • 24
    • 77951757844 scopus 로고    scopus 로고
    • Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis
    • Billeskov R., Grandal M.V., Poulsen C., Christensen J.P., Winther N., Vingsbo-Lundberg C., et al. Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis. Eur J Immunol 2010, 40:1342-1354.
    • (2010) Eur J Immunol , vol.40 , pp. 1342-1354
    • Billeskov, R.1    Grandal, M.V.2    Poulsen, C.3    Christensen, J.P.4    Winther, N.5    Vingsbo-Lundberg, C.6
  • 25
    • 9144242494 scopus 로고    scopus 로고
    • Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design
    • Vekemans J., Ota M.O., Sillah J., Fielding K., Alderson M.R., Skeiky Y.A., et al. Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design. Infect Immun 2004, 72:381-388.
    • (2004) Infect Immun , vol.72 , pp. 381-388
    • Vekemans, J.1    Ota, M.O.2    Sillah, J.3    Fielding, K.4    Alderson, M.R.5    Skeiky, Y.A.6
  • 26
    • 54349123379 scopus 로고    scopus 로고
    • Identification of genes of Mycobacterium tuberculosis upregulated during anaerobic persistence by fluorescence and kanamycin resistance selection
    • Saxena A., Srivastava V., Srivastava R., Srivastava B.S. Identification of genes of Mycobacterium tuberculosis upregulated during anaerobic persistence by fluorescence and kanamycin resistance selection. Tuberculosis (Edinb) 2008, 88:518-525.
    • (2008) Tuberculosis (Edinb) , vol.88 , pp. 518-525
    • Saxena, A.1    Srivastava, V.2    Srivastava, R.3    Srivastava, B.S.4
  • 27
    • 0032483025 scopus 로고    scopus 로고
    • The 16-kDa A-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages
    • Yuan Y., Crane D.D., Simpaon R.M., Zhu Y., Hickey M.J., Sheramn D.R., et al. The 16-kDa A-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages. Microbiology 1998, 95:9578-9583.
    • (1998) Microbiology , vol.95 , pp. 9578-9583
    • Yuan, Y.1    Crane, D.D.2    Simpaon, R.M.3    Zhu, Y.4    Hickey, M.J.5    Sheramn, D.R.6
  • 28
    • 33644914181 scopus 로고    scopus 로고
    • Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis
    • Demissie A., Leyten E.M., Abebe M., Wassie L., Aseffa A., Abate G., et al. Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin Vaccine Immunol 2006, 13:179-186.
    • (2006) Clin Vaccine Immunol , vol.13 , pp. 179-186
    • Demissie, A.1    Leyten, E.M.2    Abebe, M.3    Wassie, L.4    Aseffa, A.5    Abate, G.6
  • 29
    • 0031259833 scopus 로고    scopus 로고
    • Affinity fusion strategies for detection, purification, and immobilization of recombinant proteins
    • Nilsson J., Stahl S., Lundeberg J., Uhlen M., Nygren P.A. Affinity fusion strategies for detection, purification, and immobilization of recombinant proteins. Protein Expr Purif 1997, 11:1-16.
    • (1997) Protein Expr Purif , vol.11 , pp. 1-16
    • Nilsson, J.1    Stahl, S.2    Lundeberg, J.3    Uhlen, M.4    Nygren, P.A.5
  • 30
    • 33751046331 scopus 로고    scopus 로고
    • Production and characterization of clinical grade Escherichia coli derived Plasmodium falciparum 42kDa merozoite surface protein 1 (MSP1(42)) in the absence of an affinity tag
    • Shimp R.L., Martin L.B., Zhang Y., Henderson B.S., Duggan P., MacDonald N.J., et al. Production and characterization of clinical grade Escherichia coli derived Plasmodium falciparum 42kDa merozoite surface protein 1 (MSP1(42)) in the absence of an affinity tag. Protein Expr Purif 2006, 50:58-67.
    • (2006) Protein Expr Purif , vol.50 , pp. 58-67
    • Shimp, R.L.1    Martin, L.B.2    Zhang, Y.3    Henderson, B.S.4    Duggan, P.5    MacDonald, N.J.6
  • 32
    • 79955400032 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of a fusion protein vaccine consisting of antigen Ag85B and HspX against Mycobacterium tuberculosis infection in mice
    • Li Q., Yu H., Zhang Y., Wang B., Jiang W., Da Z., et al. Immunogenicity and protective efficacy of a fusion protein vaccine consisting of antigen Ag85B and HspX against Mycobacterium tuberculosis infection in mice. Scand J Immunol 2011, 73:568-576.
    • (2011) Scand J Immunol , vol.73 , pp. 568-576
    • Li, Q.1    Yu, H.2    Zhang, Y.3    Wang, B.4    Jiang, W.5    Da, Z.6
  • 33
    • 52349119606 scopus 로고    scopus 로고
    • Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements
    • Agger E.M., Rosenkrands I., Hansen J., Brahimi K., Vandahl B.S., Aagaard C., et al. Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements. PLoS One 2008, 3:e3116.
    • (2008) PLoS One , vol.3
    • Agger, E.M.1    Rosenkrands, I.2    Hansen, J.3    Brahimi, K.4    Vandahl, B.S.5    Aagaard, C.6
  • 34
    • 70349778463 scopus 로고    scopus 로고
    • Fusion protein Ag85B-MPT64(190-198)-Mtb8.4 has higher immunogenicity than Ag85B with capacity to boost BCG-primed immunity against Mycobacterium tuberculosis in mice
    • Luo Y., Wang B., Hu L., Yu H., Da Z., Jiang W., et al. Fusion protein Ag85B-MPT64(190-198)-Mtb8.4 has higher immunogenicity than Ag85B with capacity to boost BCG-primed immunity against Mycobacterium tuberculosis in mice. Vaccine 2009, 19(27):6179-6185.
    • (2009) Vaccine , vol.19 , Issue.27 , pp. 6179-6185
    • Luo, Y.1    Wang, B.2    Hu, L.3    Yu, H.4    Da, Z.5    Jiang, W.6
  • 35
    • 0031955285 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis reactive T cell clones from naturally converted PPD-positive healthy subjects: recognition of the M. tuberculosis 16-kDa antigen
    • Oftung F., Borka E., Mustafa A.S. Mycobacterium tuberculosis reactive T cell clones from naturally converted PPD-positive healthy subjects: recognition of the M. tuberculosis 16-kDa antigen. FEMS Immunol Med Microbiol 1998, 20:319-325.
    • (1998) FEMS Immunol Med Microbiol , vol.20 , pp. 319-325
    • Oftung, F.1    Borka, E.2    Mustafa, A.S.3
  • 36
    • 0031721317 scopus 로고    scopus 로고
    • Human T- and B-cell reactivity to the 16kDa alpha-crystallin protein of Mycobacterium tuberculosis
    • Wilkinson R.J., Wilkinson K.A., De Smet K.A., Haslov K., Pasvol G., Singh M., et al. Human T- and B-cell reactivity to the 16kDa alpha-crystallin protein of Mycobacterium tuberculosis. Scand J Immunol 1998, 48:403-409.
    • (1998) Scand J Immunol , vol.48 , pp. 403-409
    • Wilkinson, R.J.1    Wilkinson, K.A.2    De Smet, K.A.3    Haslov, K.4    Pasvol, G.5    Singh, M.6
  • 37
    • 0010908001 scopus 로고    scopus 로고
    • National Technic Steering Group Of The Epidemiological Sampling Survey For Tuberculosis. Report on fourth national epidemiological sampling survey of tuberculosis
    • [Chinese]
    • Wang K.L. National Technic Steering Group Of The Epidemiological Sampling Survey For Tuberculosis. Report on fourth national epidemiological sampling survey of tuberculosis. Chin J Tuberc Respir Dis 2002, 25:3-7. [Chinese].
    • (2002) Chin J Tuberc Respir Dis , vol.25 , pp. 3-7
    • Wang, K.L.1
  • 38
    • 77954956888 scopus 로고    scopus 로고
    • Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein
    • Shi C., Chen L., Chen Z., Zhang Y., Zhou Z., Lu J., et al. Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein. Vaccine 2010, 28:5237-5244.
    • (2010) Vaccine , vol.28 , pp. 5237-5244
    • Shi, C.1    Chen, L.2    Chen, Z.3    Zhang, Y.4    Zhou, Z.5    Lu, J.6
  • 39
    • 79751497607 scopus 로고    scopus 로고
    • A multistage tuberculosis vaccine that confers efficient protection before and after exposure
    • Aagaard C., Hoang T., Dietrich J., Cardona P.J., Izzo A., Dolganov G., et al. A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nat Med 2011, 17:189-194.
    • (2011) Nat Med , vol.17 , pp. 189-194
    • Aagaard, C.1    Hoang, T.2    Dietrich, J.3    Cardona, P.J.4    Izzo, A.5    Dolganov, G.6
  • 40
    • 0142240338 scopus 로고    scopus 로고
    • Immune control of tuberculosis by IFN-gamma-inducible LRG-47
    • MacMicking J.D., Taylor G.A., McKinney J.D. Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science 2003, 302:654-659.
    • (2003) Science , vol.302 , pp. 654-659
    • MacMicking, J.D.1    Taylor, G.A.2    McKinney, J.D.3
  • 41
    • 0035064072 scopus 로고    scopus 로고
    • Immunology of tuberculosis
    • Flynn J.L., Chan J. Immunology of tuberculosis. Annu Rev Immunol 2001, 19:93-129.
    • (2001) Annu Rev Immunol , vol.19 , pp. 93-129
    • Flynn, J.L.1    Chan, J.2
  • 43
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM induces autophagy to eliminate intracellular Mycobacteria
    • Singh S.B., Davis A.S., Taylor G.A., Deretic V. Human IRGM induces autophagy to eliminate intracellular Mycobacteria. Science 2006, 313:1438-1441.
    • (2006) Science , vol.313 , pp. 1438-1441
    • Singh, S.B.1    Davis, A.S.2    Taylor, G.A.3    Deretic, V.4
  • 44
    • 15844402155 scopus 로고    scopus 로고
    • T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
    • Fossiez F., Djossou O., Chomarat P., Flores-Romo L., Ait-Yahia S., Maat C., et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 1996, 183:2593-2603.
    • (1996) J Exp Med , vol.183 , pp. 2593-2603
    • Fossiez, F.1    Djossou, O.2    Chomarat, P.3    Flores-Romo, L.4    Ait-Yahia, S.5    Maat, C.6
  • 45
    • 34248562792 scopus 로고    scopus 로고
    • IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • Khader S.A., Bell G.K., Pearl J.E., Fountain J.J., Rangel-Moreno J., Cilley G.E., et al. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 2007, 8:369-377.
    • (2007) Nat Immunol , vol.8 , pp. 369-377
    • Khader, S.A.1    Bell, G.K.2    Pearl, J.E.3    Fountain, J.J.4    Rangel-Moreno, J.5    Cilley, G.E.6
  • 46
    • 46749121412 scopus 로고    scopus 로고
    • Tuberculosis vaccine development: goals, immunological design, and evaluation
    • Hoft D.F. Tuberculosis vaccine development: goals, immunological design, and evaluation. Lancet 2008, 372:164-175.
    • (2008) Lancet , vol.372 , pp. 164-175
    • Hoft, D.F.1
  • 47
    • 25444484121 scopus 로고    scopus 로고
    • Enhancement of innate and cell-mediated immunity by antimycobacterial antibodies
    • de Valliere S., Abate G., Blazevic A., Heuertz R.M., Hoft D.F. Enhancement of innate and cell-mediated immunity by antimycobacterial antibodies. Infect Immun 2005, 73:6711-6720.
    • (2005) Infect Immun , vol.73 , pp. 6711-6720
    • de Valliere, S.1    Abate, G.2    Blazevic, A.3    Heuertz, R.M.4    Hoft, D.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.