In search of novel highly active mitochondria-targeted antioxidants: Thymoquinone and its cationic derivatives

FEBS Letters

Volumn 587, Issue 13, 2013, Pages 2018-2024

  Severina, Inna I ^a   Severin, Fedor F ^a   Korshunova, Galina A ^a   Sumbatyan, Natalya V ^a   Ilyasova, Tatyana M ^a   Simonyan, Ruben A ^a   Rogov, Anton G ^b   Trendeleva, Tatyana A ^b   Zvyagilskaya, Renata A ^b   Dugina, Vera B ^b   Domnina, Lidia V ^a   Fetisova, Elena K ^a   Lyamzaev, Konstantin G ^a   Vyssokikh, Mikhail Yu ^a   Chernyak, Boris V ^a   Skulachev, Maxim V ^a   Skulachev, Vladimir P ^a   Sadovnichii, Viktor A ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

Author keywords

Thymoquinone SkQ Mitochondria targeted antioxidant Apoptosis Reactive oxygen species Cancer

Indexed keywords

2 NORPLASTOQUINONE; ANTIOXIDANT; CATION; HYDROGEN PEROXIDE; PLASTOQUINONE; PLASTOQUINONE DERIVATIVE; THYMOQUINONE; THYMOQUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY CHAIN; REVIEW;

ANIMALS; ANTIOXIDANTS; BENZOQUINONES; CATIONS; CELL MEMBRANE PERMEABILITY; DRUG DELIVERY SYSTEMS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATION-REDUCTION; PLASTOQUINONE; REACTIVE OXYGEN SPECIES;

NIGELLA SATIVA;

EID: 84878934179     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.04.043     Document Type: Review

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