Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma

Biochimica et Biophysica Acta - General Subjects

Volumn 1760, Issue 7, 2006, Pages 1088-1095

  El Gazzar, Mohamed ^a   El Mezayen, Rabab ^a   Nicolls, Mark R ^a   Marecki, John C ^a   Dreskin, Stephen C ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

5 lipoxygenase; Inflammation; Leukotrienes; Th2 cytokines; Thymoquinone

Indexed keywords

2 ISOPROPYL 5 METHYL 1,4 BENZOQUINONE; ANTIGEN; ARACHIDONATE 5 LIPOXYGENASE; CYTOKINE; ESSENTIAL OIL; LEUKOTRIENE; LEUKOTRIENE B4; LEUKOTRIENE C4; NIGELLA SATIVA EXTRACT; OVALBUMIN; THYMOQUINONE; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL COUNT; CELL FUNCTION; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; EOSINOPHIL; EOSINOPHILIA; FATTY ACID ANALYSIS; FATTY ACID SYNTHESIS; FEMALE; GOBLET CELL; LUNG ALVEOLUS CELL; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PLANT SEED; PRIORITY JOURNAL; PROVOCATION TEST; RESPIRATORY TRACT INFLAMMATION; SENSITIZATION; TH2 CELL;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; ASTHMA; BENZOQUINONES; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; HYPERSENSITIVITY; INFLAMMATION; LEUKOTRIENES; LUNG; MALE; MICE; MICE, INBRED BALB C; NIGELLA SATIVA;

NIGELLA SATIVA;

EID: 33745007923     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2006.03.006     Document Type: Article

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