-
1
-
-
5144231704
-
Expression of the tumor suppressor gene ARHI in epithelial ovarian cancer is associated with increased expression of p21WAF1/CIP1 and prolonged progression-free survival
-
PMID:15475444
-
Rosen DG, Wang L, Jain AN, Lu KH, Luo RZ, Yu Y, et al. Expression of the tumor suppressor gene ARHI in epithelial ovarian cancer is associated with increased expression of p21WAF1/CIP1 and prolonged progression-free survival. Clin Cancer Res 2004; 10:6559-66; PMID:15475444; http://dx.doi.org/10.1158/1078- 0432.CCR-04-0698
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6559-6566
-
-
Rosen, D.G.1
Wang, L.2
Jain, A.N.3
Lu, K.H.4
Luo, R.Z.5
Yu, Y.6
-
2
-
-
84855355011
-
The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways
-
PMID:21643014
-
Badgwell DB, Lu Z, Le K, Gao F, Yang M, Suh GK, et al. The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways. Oncogene 2012; 31:68-79; PMID:21643014; http://dx.doi.org/10.1038/onc.2011.213
-
(2012)
Oncogene
, vol.31
, pp. 68-79
-
-
Badgwell, D.B.1
Lu, Z.2
Le, K.3
Gao, F.4
Yang, M.5
Suh, G.K.6
-
3
-
-
78650842745
-
MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer
-
Phila PMID:21071579
-
Chen Y, Zaman MS, Deng G, Majid S, Saini S, Liu J, et al. MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer. Cancer Prev Res (Phila) 2011; 4:76-86; PMID:21071579; http://dx.doi.org/10.1158/1940-6207.CAPR-10-0167
-
(2011)
Cancer Prev Res
, vol.4
, pp. 76-86
-
-
Chen, Y.1
Zaman, M.S.2
Deng, G.3
Majid, S.4
Saini, S.5
Liu, J.6
-
4
-
-
57449121645
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
-
PMID:19033662.
-
Lu Z, Luo RZ, Lu Y, Zhang X, Yu Q, Khare S, et al. The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells. J Clin Invest 2008; 118:3917-29; PMID:19033662.
-
(2008)
J Clin Invest
, vol.118
, pp. 3917-3929
-
-
Lu, Z.1
Luo, R.Z.2
Lu, Y.3
Zhang, X.4
Yu, Q.5
Khare, S.6
-
5
-
-
0034282543
-
The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice
-
PMID:10987306
-
Xu F, Xia W, Luo RZ, Peng H, Zhao S, Dai J, et al. The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice. Cancer Res 2000; 60:4913-20; PMID:10987306.
-
(2000)
Cancer Res
, vol.60
, pp. 4913-4920
-
-
Xu, F.1
Xia, W.2
Luo, R.Z.3
Peng, H.4
Zhao, S.5
Dai, J.6
-
6
-
-
33744528546
-
Biochemistry and biology of ARHI (DIRAS3), an imprinted tumor suppressor gene whose expression is lost in ovarian and breast cancers
-
PMID:16757345
-
Yu Y, Luo R, Lu Z, Wei Feng W, Badgwell D, Issa JP, et al. Biochemistry and biology of ARHI (DIRAS3), an imprinted tumor suppressor gene whose expression is lost in ovarian and breast cancers. Methods Enzymol 2006; 407:455-68; PMID:16757345; http://dx.doi.org/10.1016/S0076-6879(05)07037-0
-
(2006)
Methods Enzymol
, vol.407
, pp. 455-468
-
-
Yu, Y.1
Luo, R.2
Lu, Z.3
Wei Feng, W.4
Badgwell, D.5
Issa, J.P.6
-
7
-
-
84857735762
-
A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbß3 integrin coactivation
-
PMID:22235127
-
Bouaouina M, Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, et al. A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbß3 integrin coactivation. J Biol Chem 2012; 287:6979-90; PMID:22235127; http://dx.doi.org/10.1074/jbc.M111.330845
-
(2012)
J Biol Chem
, vol.287
, pp. 6979-6990
-
-
Bouaouina, M.1
Goult, B.T.2
Huet-Calderwood, C.3
Bate, N.4
Brahme, N.N.5
Barsukov, I.L.6
-
8
-
-
84867885462
-
ILK: A pseudokinase in the center stage of cell-matrix adhesion and signaling
-
PMID:22763012
-
Qin J, Wu C. ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling. Curr Opin Cell Biol 2012; 24:607-13; PMID:22763012; http://dx.doi.org/10.1016/j.ceb.2012.06.003
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 607-613
-
-
Qin, J.1
Wu, C.2
-
9
-
-
84867178220
-
Role of α5β1 and αvβ3 integrins in relation to adhesion and spreading dynamics of prostate cancer cells interacting with fibronectin under in vitro conditions
-
PMID:22686483
-
Stachurska A, Elbanowski J, Kowalczyńska HM. Role of α5β1 and αvβ3 integrins in relation to adhesion and spreading dynamics of prostate cancer cells interacting with fibronectin under in vitro conditions. Cell Biol Int 2012; 36:883-92; PMID:22686483; http://dx.doi.org/10.1042/CBI20110522
-
(2012)
Cell Biol Int
, vol.36
, pp. 883-892
-
-
Stachurska, A.1
Elbanowski, J.2
Kowalczyńska, H.M.3
-
10
-
-
61649121052
-
Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome
-
PMID:19035362
-
Rosenberger G, Meien S, Kutsche K. Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome. Hum Mutat 2009; 30:352-62; PMID:19035362; http://dx.doi.org/10.1002/humu.20855
-
(2009)
Hum Mutat
, vol.30
, pp. 352-362
-
-
Rosenberger, G.1
Meien, S.2
Kutsche, K.3
-
11
-
-
0141726738
-
Interaction of integrin receptors with extracellular matrix is involved in trophoblast giant cell migration in bovine placentomes
-
PMID:12828918
-
Pfarrer C, Hirsch P, Guillomot M, Leiser R. Interaction of integrin receptors with extracellular matrix is involved in trophoblast giant cell migration in bovine placentomes. Placenta 2003; 24:588-97 PMID:12828918; http://dx.doi.org/10.1016/S0143-4004(03)00059-6
-
(2003)
Placenta
, vol.24
, pp. 588-597
-
-
Pfarrer, C.1
Hirsch, P.2
Guillomot, M.3
Leiser, R.4
-
12
-
-
0034742548
-
Prognostic value of beta1-integrin (=CD29) in serous adenocarcinomas of the ovary
-
PMID:11501844
-
Müller-Klingspor V, Hefler L, Obermair A, Kaider A, Breitenecker G, Leodolte S, et al. Prognostic value of beta1-integrin (=CD29) in serous adenocarcinomas of the ovary. Anticancer Res 2001; 21(3C):2185-8; PMID:11501844.
-
(2001)
Anticancer Res
, vol.21
, Issue.3 C
, pp. 2185-2188
-
-
Müller-Klingspor, V.1
Hefler, L.2
Obermair, A.3
Kaider, A.4
Breitenecker, G.5
Leodolte, S.6
-
13
-
-
84863358460
-
Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: Effect on β1 integrin activity and α-SMA stress fiber assembly
-
PMID:22470492
-
Wang L, Pedroja BS, Meyers EE, Garcia AL, Twining SS, Bernstein AM. Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly. PLoS One 2012; 7:e33915; PMID:22470492; http://dx.doi.org/10.1371/journal.pone. 0033915
-
(2012)
PLoS One
, vol.7
-
-
Wang, L.1
Pedroja, B.S.2
Meyers, E.E.3
Garcia, A.L.4
Twining, S.S.5
Bernstein, A.M.6
-
14
-
-
84879414971
-
Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways
-
In press; PMID:22824793
-
Bianchi-Smiraglia A, Paesante S, Bakin AV. Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways. Oncogene 2012; In press; PMID:22824793; http://dx.doi.org/10.1038/onc.2012.320
-
(2012)
Oncogene
-
-
Bianchi-Smiraglia, A.1
Paesante, S.2
Bakin, A.V.3
-
15
-
-
84862907457
-
VEGF-induced vascular permeability is mediated by FAK
-
PMID:22264731
-
Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, et al. VEGF-induced vascular permeability is mediated by FAK. Dev Cell 2012; 22:146-57; PMID:22264731; http://dx.doi.org/10.1016/j.dev-cel.2011.11.002
-
(2012)
Dev Cell
, vol.22
, pp. 146-157
-
-
Chen, X.L.1
Nam, J.O.2
Jean, C.3
Lawson, C.4
Walsh, C.T.5
Goka, E.6
-
16
-
-
84867243955
-
Integrin adhesions: Who's on first? What's on second? Connections between FAK and talin
-
PMID:22983197
-
Lawson C, Schlaepfer DD. Integrin adhesions: who's on first? What's on second? Connections between FAK and talin. Cell Adh Migr 2012; 6:302-6; PMID:22983197; http://dx.doi.org/10.4161/cam.20488
-
(2012)
Cell Adh Migr
, vol.6
, pp. 302-306
-
-
Lawson, C.1
Schlaepfer, D.D.2
-
17
-
-
80051499176
-
Integrin αvβ3 promotes vitronectin gene expression in human ovarian cancer cells by implicating rel transcription factors
-
PMID:21433063
-
Reuning U. Integrin αvβ3 promotes vitronectin gene expression in human ovarian cancer cells by implicating rel transcription factors. J Cell Biochem 2011; 112:1909-19; PMID:21433063; http://dx.doi.org/10.1002/jcb.23111
-
(2011)
J Cell Biochem
, vol.112
, pp. 1909-1919
-
-
Reuning, U.1
-
18
-
-
51249114772
-
Integrin alphavbeta3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells
-
PMID:18577466
-
Lössner D, Abou-Ajram C, Benge A, Reuning U. Integrin alphavbeta3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells. Int J Biochem Cell Biol 2008; 40:2746-61; PMID:18577466; http://dx.doi.org/10.1016/j.biocel.2008.05.014
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 2746-2761
-
-
Lössner, D.1
Abou-Ajram, C.2
Benge, A.3
Reuning, U.4
-
19
-
-
84857198559
-
Norepinephrine promotes the β1-integrin-mediated adhesion of MDA-MB-231 cells to vascular endothelium by the induction of a GROα release
-
PMID:22127496
-
Strell C, Niggemann B, Voss MJ, Powe DG, Zanker KS, Entschladen F. Norepinephrine promotes the β1-integrin-mediated adhesion of MDA-MB-231 cells to vascular endothelium by the induction of a GROα release. Mol Cancer Res 2012; 10:197-207; PMID:22127496; http://dx.doi.org/10.1158/1541-7786. MCR-11-0130
-
(2012)
Mol Cancer Res
, vol.10
, pp. 197-207
-
-
Strell, C.1
Niggemann, B.2
Voss, M.J.3
Powe, D.G.4
Zanker, K.S.5
Entschladen, F.6
-
20
-
-
81155126053
-
Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth
-
PMID:21948958
-
Schmid MC, Avraamides CJ, Foubert P, Shaked Y, Kang SW, Kerbel RS, et al. Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth. Cancer Res 2011; 71:6965-75; PMID:21948958; http://dx.doi.org/10.1158/0008-5472.CAN-11-0588
-
(2011)
Cancer Res
, vol.71
, pp. 6965-6975
-
-
Schmid, M.C.1
Avraamides, C.J.2
Foubert, P.3
Shaked, Y.4
Kang, S.W.5
Kerbel, R.S.6
-
21
-
-
79551718325
-
Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis
-
PMID:21149615
-
Kenny HA, Leonhardt P, Ladanyi A, Yamada SD, Montag A, Im HK, et al. Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis. Clin Cancer Res 2011; 17:459-71; PMID:21149615; http://dx.doi.org/ 10.1158/1078-0432.CCR-10-2258
-
(2011)
Clin Cancer Res
, vol.17
, pp. 459-471
-
-
Kenny, H.A.1
Leonhardt, P.2
Ladanyi, A.3
Yamada, S.D.4
Montag, A.5
Im, H.K.6
-
22
-
-
77953548597
-
A prognostic gene signature in advanced ovarian cancer reveals a microfibril-associated protein (MAGP2) as a promoter of tumor cell survival and angiogenesis
-
PMID:20400864
-
Spivey KA, Banyard J. A prognostic gene signature in advanced ovarian cancer reveals a microfibril-associated protein (MAGP2) as a promoter of tumor cell survival and angiogenesis. Cell Adh Migr 2010; 4:169-71; PMID:20400864; http://dx.doi.org/10.4161/cam.4.2.11716
-
(2010)
Cell Adh Migr
, vol.4
, pp. 169-171
-
-
Spivey, K.A.1
Banyard, J.2
-
23
-
-
77950818717
-
Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5) beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma
-
PMID:20332224
-
Dong Y, Tan OL, Loessner D, Stephens C, Walpole C, Boyle GM, et al. Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5) beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma. Cancer Res 2010; 70:2624-33; PMID:20332224; http://dx.doi.org/10.1158/0008-5472.CAN-09-3415
-
(2010)
Cancer Res
, vol.70
, pp. 2624-2633
-
-
Dong, Y.1
Tan, O.L.2
Loessner, D.3
Stephens, C.4
Walpole, C.5
Boyle, G.M.6
-
24
-
-
77953381842
-
Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion
-
PMID:20187934
-
Shepherd TG, Mujoomdar ML, Nachtigal MW. Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion. J Ovarian Res 2010; 3:5; PMID:20187934; http://dx.doi.org/10.1186/ 1757-2215-3-5
-
(2010)
J Ovarian Res
, vol.3
, pp. 5
-
-
Shepherd, T.G.1
Mujoomdar, M.L.2
Nachtigal, M.W.3
-
25
-
-
60549088136
-
Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis
-
PMID:19208843
-
Slack-Davis JK, Atkins KA, Harrer C, Hershey ED, Conaway M. Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis. Cancer Res 2009; 69:1469-76; PMID:19208843; http://dx.doi.org/10.1158/0008-5472. CAN-08-2678
-
(2009)
Cancer Res
, vol.69
, pp. 1469-1476
-
-
Slack-Davis, J.K.1
Atkins, K.A.2
Harrer, C.3
Hershey, E.D.4
Conaway, M.5
-
26
-
-
69249235848
-
Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells
-
PMID:19475568
-
Chen YJ, Wei YY, Chen HT, Fong YC, Hsu CJ, Tsai CH, et al. Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells. J Cell Physiol 2009; 221:98-108; PMID:19475568; http://dx.doi.org/10.1002/jcp.21835
-
(2009)
J Cell Physiol
, vol.221
, pp. 98-108
-
-
Chen, Y.J.1
Wei, Y.Y.2
Chen, H.T.3
Fong, Y.C.4
Hsu, C.J.5
Tsai, C.H.6
-
27
-
-
66149098432
-
CTGF enhances migration and MMP-13 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells
-
PMID:19301259
-
Tan TW, Lai CH, Huang CY, Yang WH, Chen HT, Hsu HC, et al. CTGF enhances migration and MMP-13 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells. J Cell Biochem 2009; 107:345-56; PMID:19301259; http://dx.doi.org/10.1002/jcb.22132
-
(2009)
J Cell Biochem
, vol.107
, pp. 345-356
-
-
Tan, T.W.1
Lai, C.H.2
Huang, C.Y.3
Yang, W.H.4
Chen, H.T.5
Hsu, H.C.6
-
28
-
-
68949092126
-
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2
-
PMID:19033423
-
Baumann F, Leukel P, Doerfelt A, Beier CP, Dettmer K, Oefner PJ, et al. Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol 2009; 11:368-80; PMID:19033423; http://dx.doi.org/10.1215/15228517-2008-106
-
(2009)
Neuro Oncol
, vol.11
, pp. 368-380
-
-
Baumann, F.1
Leukel, P.2
Doerfelt, A.3
Beier, C.P.4
Dettmer, K.5
Oefner, P.J.6
-
29
-
-
78549272759
-
Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action
-
PMID:21076489
-
Mukherjee S, Ray D, Lekli I, Bak I, Tosaki A, Das DK. Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action. Can J Physiol Pharmacol 2010; 88:1017-25; PMID:21076489; http://dx.doi.org/10.1139/Y10-082
-
(2010)
Can J Physiol Pharmacol
, vol.88
, pp. 1017-1025
-
-
Mukherjee, S.1
Ray, D.2
Lekli, I.3
Bak, I.4
Tosaki, A.5
Das, D.K.6
-
30
-
-
77957942243
-
Anticancer properties of the IL-12 family - Focus on colorectal cancer
-
PMID:20712574
-
Engel MA, Neurath MF. Anticancer properties of the IL-12 family - focus on colorectal cancer. Curr Med Chem 2010; 17:3303-8; PMID:20712574; http://dx.doi.org/10.2174/092986710793176366
-
(2010)
Curr Med Chem
, vol.17
, pp. 3303-3308
-
-
Engel, M.A.1
Neurath, M.F.2
-
31
-
-
84863436368
-
Androgen metabolism and JAK/STAT pathway genes and prostate cancer risk
-
PMID:22542949
-
Kwon EM, Holt SK, Fu R, Kolb S, Williams G, Stanford JL, et al. Androgen metabolism and JAK/STAT pathway genes and prostate cancer risk. Cancer Epidemiol 2012; 36:347-53; PMID:22542949; http://dx.doi.org/10.1016/j.canep.2012.04.002
-
(2012)
Cancer Epidemiol
, vol.36
, pp. 347-353
-
-
Kwon, E.M.1
Holt, S.K.2
Fu, R.3
Kolb, S.4
Williams, G.5
Stanford, J.L.6
-
32
-
-
13944279557
-
Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential
-
PMID:15558012
-
Meinhold-Heerlein I, Bauerschlag D, Hilpert F, Dimitrov P, Sapinoso LM, Orlowska-Volk M, et al. Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential. Oncogene 2005; 24:1053-65; PMID:15558012; http://dx.doi.org/10.1038/sj.onc.1208298
-
(2005)
Oncogene
, vol.24
, pp. 1053-1065
-
-
Meinhold-Heerlein, I.1
Bauerschlag, D.2
Hilpert, F.3
Dimitrov, P.4
Sapinoso, L.M.5
Orlowska-Volk, M.6
-
33
-
-
84867499521
-
Interleukin-6/interleukin-6 receptor pathway as a new therapy target in epithelial ovarian cancer
-
PMID:22591418
-
Dijkgraaf EM, Welters MJ, Nortier JW, van der Burg SH, Kroep JR. Interleukin-6/interleukin-6 receptor pathway as a new therapy target in epithelial ovarian cancer. Curr Pharm Des 2012; 18:3816-27; PMID:22591418; http://dx.doi.org/10.2174/138161212802002797
-
(2012)
Curr Pharm des
, vol.18
, pp. 3816-3827
-
-
Dijkgraaf, E.M.1
Welters, M.J.2
Nortier, J.W.3
Van Der Burg, S.H.4
Kroep, J.R.5
-
34
-
-
58149218143
-
Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas
-
PMID:19088723
-
Colomiere M, Ward AC, Riley C, Trenerry MK, Cameron-Smith D, Findlay J, et al. Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas. Br J Cancer 2009; 100:134-44; PMID:19088723; http://dx.doi.org/10.1038/sj.bjc.6604794
-
(2009)
Br J Cancer
, vol.100
, pp. 134-144
-
-
Colomiere, M.1
Ward, A.C.2
Riley, C.3
Trenerry, M.K.4
Cameron-Smith, D.5
Findlay, J.6
-
35
-
-
33845310503
-
SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation
-
PMID:17121906
-
Duan Z, Bradner JE, Greenberg E, Levine R, Foster R, Mahoney J, et al. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation. Clin Cancer Res 2006; 12:6844-52; PMID:17121906; http://dx.doi.org/10.1158/1078-0432.CCR-06-1330
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6844-6852
-
-
Duan, Z.1
Bradner, J.E.2
Greenberg, E.3
Levine, R.4
Foster, R.5
Mahoney, J.6
-
36
-
-
34250217027
-
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6
-
PMID:17438134
-
Azare J, Leslie K, Al-Ahmadie H, Gerald W, Weinreb PH, Violette SM, et al. Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6. Mol Cell Biol 2007; 27:4444-53; PMID:17438134; http://dx.doi.org/10.1128/MCB.02404-06
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4444-4453
-
-
Azare, J.1
Leslie, K.2
Al-Ahmadie, H.3
Gerald, W.4
Weinreb, P.H.5
Violette, S.M.6
-
37
-
-
77952315859
-
Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro
-
PMID:20482858
-
Huang C, Yang G, Jiang T, Huang K, Cao J, Qiu Z. Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro. J Exp Clin Cancer Res 2010; 29:51; PMID:20482858; http://dx.doi.org/10.1186/1756-9966-29-51
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 51
-
-
Huang, C.1
Yang, G.2
Jiang, T.3
Huang, K.4
Cao, J.5
Qiu, Z.6
-
38
-
-
59149083547
-
Beta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: Implications for microenvironment influence on tumor survival and proliferation
-
PMID:19155309
-
Shain KH, Yarde DN, Meads MB, Huang M, Jove R, Hazlehurst LA, et al. Beta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation. Cancer Res 2009; 69:1009-15; PMID:19155309; http://dx.doi.org/10. 1158/0008-5472.CAN-08-2419
-
(2009)
Cancer Res
, vol.69
, pp. 1009-1015
-
-
Shain, K.H.1
Yarde, D.N.2
Meads, M.B.3
Huang, M.4
Jove, R.5
Hazlehurst, L.A.6
-
39
-
-
77951735629
-
IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1
-
PMID:20428809
-
Li R, Li G, Deng L, Liu Q, Dai J, Shen J, et al. IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1. Oncol Rep 2010; 23:1553-9; PMID:20428809; http://dx.doi.org/10.3892/or-00000795
-
(2010)
Oncol Rep
, vol.23
, pp. 1553-1559
-
-
Li, R.1
Li, G.2
Deng, L.3
Liu, Q.4
Dai, J.5
Shen, J.6
-
40
-
-
75149192643
-
IL-6 regulates MMP-10 expression via JAK2/STAT3 signaling pathway in a human lung adenocarcinoma cell line
-
PMID:20032397
-
Zhang X, Yin P, Di D, Luo G, Zheng L, Wei J, et al. IL-6 regulates MMP-10 expression via JAK2/STAT3 signaling pathway in a human lung adenocarcinoma cell line. Anticancer Res 2009; 29:4497-501; PMID:20032397.
-
(2009)
Anticancer Res
, vol.29
, pp. 4497-4501
-
-
Zhang, X.1
Yin, P.2
Di, D.3
Luo, G.4
Zheng, L.5
Wei, J.6
-
41
-
-
0033624445
-
Matrix metalloproteinases: Molecular aspects of their roles in tumour invasion and metastasis
-
PMID:10959048
-
Curran S, Murray GI. Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis. Eur J Cancer 2000; 36(13 Spec No):1621-30; PMID:10959048; http://dx.doi.org/10.1016/S0959-8049(00)00156-8
-
(2000)
Eur J Cancer
, vol.36
, Issue.13 SPEC NO
, pp. 1621-1630
-
-
Curran, S.1
Murray, G.I.2
-
42
-
-
84872598543
-
Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma
-
PMID:22349830
-
Kesanakurti D, Chetty C, Dinh DH, Gujrati M, Rao JS. Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma. Oncogene 2013; 32:327-40; PMID:22349830; http://dx.doi.org/10.1038/onc.2012.52
-
(2013)
Oncogene
, vol.32
, pp. 327-340
-
-
Kesanakurti, D.1
Chetty, C.2
Dinh, D.H.3
Gujrati, M.4
Rao, J.S.5
-
43
-
-
34547141141
-
Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis
-
PMID:17567918
-
Shield K, Riley C, Quinn MA, Rice GE, Ackland ML, Ahmed N. Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis. J Carcinog 2007; 6:11; PMID:17567918; http://dx.doi.org/10.1186/1477-3163-6-11
-
(2007)
J Carcinog
, vol.6
, pp. 11
-
-
Shield, K.1
Riley, C.2
Quinn, M.A.3
Rice, G.E.4
Ackland, M.L.5
Ahmed, N.6
-
44
-
-
14844315007
-
Transmigration of human ovarian adenocarcinoma cells through endothelial extracellular matrix involves alphav integrins and the participation of MMP2
-
PMID:15609323
-
Leroy-Dudal J, Demeilliers C, Gallet O, Pauthe E, Dutoit S, Agniel R, et al. Transmigration of human ovarian adenocarcinoma cells through endothelial extracellular matrix involves alphav integrins and the participation of MMP2. Int J Cancer 2005; 114:531-43; PMID:15609323; http://dx.doi.org/10.1002/ijc. 20778
-
(2005)
Int J Cancer
, vol.114
, pp. 531-543
-
-
Leroy-Dudal, J.1
Demeilliers, C.2
Gallet, O.3
Pauthe, E.4
Dutoit, S.5
Agniel, R.6
-
45
-
-
77956823141
-
Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles
-
2010; PMID:20847951
-
Hamadi A, Deramaudt TB, Takeda K, Rondé P. Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles. J Oncol 2010; 2010; PMID:20847951; http://dx.doi.org/10.1155/2010/932803
-
(2010)
J Oncol
-
-
Hamadi, A.1
Deramaudt, T.B.2
Takeda, K.3
Rondé, P.4
-
46
-
-
77957354086
-
ECM-dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK and p38 MAPK of osteoblast-like cells
-
PMID:20507284
-
Hamamura K, Jiang C, Yokota H. ECM-dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK and p38 MAPK of osteoblast-like cells. Cell Biol Int 2010; 34:1005-12; PMID:20507284; http://dx.doi.org/10.1042/ CBI20100069
-
(2010)
Cell Biol Int
, vol.34
, pp. 1005-1012
-
-
Hamamura, K.1
Jiang, C.2
Yokota, H.3
-
47
-
-
77954917015
-
Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway
-
PMID:20472666
-
Zhu H, Liu XW, Cai TY, Cao J, Tu CX, Lu W, et al. Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway. J Pharmacol Exp Ther 2010; 334:489-99; PMID:20472666; http://dx.doi.org/10.1124/jpet.110.165654
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 489-499
-
-
Zhu, H.1
Liu, X.W.2
Cai, T.Y.3
Cao, J.4
Tu, C.X.5
Lu, W.6
-
48
-
-
79959616373
-
Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway
-
PMID:21720547
-
Shi C, Lu J, Wu W, Ma F, Georges J, Huang H, et al. Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway. PLoS One 2011; 6:e21482; PMID:21720547; http://dx.doi.org/10.1371/journal.pone.0021482
-
(2011)
PLoS One
, vol.6
-
-
Shi, C.1
Lu, J.2
Wu, W.3
Ma, F.4
Georges, J.5
Huang, H.6
-
49
-
-
33846666657
-
Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells
-
PMID:17234779
-
Tabe Y, Jin L, Tsutsumi-Ishii Y, Xu Y, McQueen T, Priebe W, et al. Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells. Cancer Res 2007; 67:684-94; PMID:17234779; http://dx.doi.org/10.1158/0008-5472.CAN-06-3166
-
(2007)
Cancer Res
, vol.67
, pp. 684-694
-
-
Tabe, Y.1
Jin, L.2
Tsutsumi-Ishii, Y.3
Xu, Y.4
McQueen, T.5
Priebe, W.6
-
50
-
-
79959851522
-
Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes
-
PMID:21451103
-
Routray C, Liu C, Yaqoob U, Billadeau DD, Bloch KD, Kaibuchi K, et al. Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes. Am J Physiol Cell Physiol 2011; 301:C66-74; PMID:21451103; http://dx.doi.org/10.1152/ajpcell.00038.2011
-
(2011)
Am J Physiol Cell Physiol
, vol.301
-
-
Routray, C.1
Liu, C.2
Yaqoob, U.3
Billadeau, D.D.4
Bloch, K.D.5
Kaibuchi, K.6
-
51
-
-
35648963605
-
Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration
-
PMID:17716979
-
Miertzschke M, Stanley P, Bunney TD, Rodrigues-Lima F, Hogg N, Katan M. Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration. J Biol Chem 2007; 282:30629-42; PMID:17716979; http://dx.doi.org/10.1074/jbc.M704361200
-
(2007)
J Biol Chem
, vol.282
, pp. 30629-30642
-
-
Miertzschke, M.1
Stanley, P.2
Bunney, T.D.3
Rodrigues-Lima, F.4
Hogg, N.5
Katan, M.6
-
52
-
-
0036142219
-
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
-
PMID:11784865
-
Hagel M, George EL, Kim A, Tamimi R, Opitz SL, Turner CE, et al. The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Mol Cell Biol 2002; 22:901-15; PMID:11784865; http://dx.doi.org/10.1128/MCB.22.3.901-915.2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 901-915
-
-
Hagel, M.1
George, E.L.2
Kim, A.3
Tamimi, R.4
Opitz, S.L.5
Turner, C.E.6
-
53
-
-
84867760556
-
Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrier
-
PMID:22898813
-
Kim JC, Crary B, Chang YC, Kwon-Chung KJ, Kim KJ. Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrier. J Biol Chem 2012; 287:36147-57; PMID:22898813; http://dx.doi.org/10.1074/jbc.M112. 389676
-
(2012)
J Biol Chem
, vol.287
, pp. 36147-36157
-
-
Kim, J.C.1
Crary, B.2
Chang, Y.C.3
Kwon-Chung, K.J.4
Kim, K.J.5
-
54
-
-
79953690220
-
The role of mechanical stretching in the activation and localization of adhesion proteins and related intracellular molecules
-
PMID:21321993
-
Boccafoschi F, Mosca C, Bosetti M, Cannas M. The role of mechanical stretching in the activation and localization of adhesion proteins and related intracellular molecules. J Cell Biochem 2011; 112:1403-9; PMID:21321993; http://dx.doi.org/10.1002/jcb.23056
-
(2011)
J Cell Biochem
, vol.112
, pp. 1403-1409
-
-
Boccafoschi, F.1
Mosca, C.2
Bosetti, M.3
Cannas, M.4
-
55
-
-
33745589519
-
Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex
-
PMID:16440329
-
Payne SL, Hendrix MJ, Kirschmann DA. Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex. J Cell Biochem 2006; 98:827-37; PMID:16440329; http://dx.doi.org/10.1002/jcb.20792
-
(2006)
J Cell Biochem
, vol.98
, pp. 827-837
-
-
Payne, S.L.1
Hendrix, M.J.2
Kirschmann, D.A.3
-
56
-
-
79953220086
-
Ligand-independent activation of c-Met by fibronectin and α(5)β(1)-integrin regulates ovarian cancer invasion and metastasis
-
PMID:21119598
-
Mitra AK, Sawada K, Tiwari P, Mui K, Gwin K, Lengyel E. Ligand-independent activation of c-Met by fibronectin and α(5)β(1)- integrin regulates ovarian cancer invasion and metastasis. Oncogene 2011; 30:1566-76; PMID:21119598; http://dx.doi.org/10.1038/onc.2010.532
-
(2011)
Oncogene
, vol.30
, pp. 1566-1576
-
-
Mitra, A.K.1
Sawada, K.2
Tiwari, P.3
Mui, K.4
Gwin, K.5
Lengyel, E.6
-
57
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
PMID:7536630
-
Nobes CD, Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995; 81:53-62; PMID:7536630; http://dx.doi.org/10.1016/0092-8674(95)90370-4
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
58
-
-
34247281958
-
Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction
-
PMID:17460772
-
Tsareva SA, Moriggl R, Corvinus FM, Wiederanders B, Schütz A, Kovacic B, et al. Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction. Neoplasia 2007; 9:279-91; PMID:17460772; http://dx.doi.org/10.1593/ neo.06820
-
(2007)
Neoplasia
, vol.9
, pp. 279-291
-
-
Tsareva, S.A.1
Moriggl, R.2
Corvinus, F.M.3
Wiederanders, B.4
Schütz, A.5
Kovacic, B.6
-
59
-
-
84861213963
-
N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration
-
PMID:22275437
-
Camand E, Peglion F, Osmani N, Sanson M, Etienne-Manneville S. N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration. J Cell Sci 2012; 125:844-57; PMID:22275437; http://dx.doi.org/10.1242/jcs.087668
-
(2012)
J Cell Sci
, vol.125
, pp. 844-857
-
-
Camand, E.1
Peglion, F.2
Osmani, N.3
Sanson, M.4
Etienne-Manneville, S.5
-
60
-
-
83555176312
-
Prognostic role of integrin β1, E-cadherin, and rac1 expression in small cell lung cancer
-
PMID:22151306
-
Chang MH, Lee K, Lee KY, Kim YS, Kim YK, Kang JH. Prognostic role of integrin β1, E-cadherin, and rac1 expression in small cell lung cancer. APMIS 2012; 120:28-38; PMID:22151306; http://dx.doi.org/10.1111/j.1600-0463. 2011.02788.x
-
(2012)
APMIS
, vol.120
, pp. 28-38
-
-
Chang, M.H.1
Lee, K.2
Lee, K.Y.3
Kim, Y.S.4
Kim, Y.K.5
Kang, J.H.6
-
61
-
-
84863051239
-
Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation
-
PMID:22049212
-
O'Connor KL, Chen M, Towers LN. Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation. Am J Physiol Cell Physiol 2012; 302:C605-14; PMID:22049212; http://dx.doi.org/10. 1152/ajp-cell.00095.2011
-
(2012)
Am J Physiol Cell Physiol
, vol.302
-
-
O'Connor, K.L.1
Chen, M.2
Towers, L.N.3
-
62
-
-
70350411154
-
Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage
-
PMID:19796635
-
Lydolph MC, Morgan-Fisher M, Høye AM, Couchman JR, Wewer UM, Yoneda A. Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage. Exp Cell Res 2009; 315:3312-24; PMID:19796635; http://dx.doi.org/10.1016/j.yexcr.2009.09.022
-
(2009)
Exp Cell Res
, vol.315
, pp. 3312-3324
-
-
Lydolph, M.C.1
Morgan-Fisher, M.2
Høye, A.M.3
Couchman, J.R.4
Wewer, U.M.5
Yoneda, A.6
-
63
-
-
80555149256
-
RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration
-
PMID:22001926
-
Rousseau M, Gaugler MH, Rodallec A, Bonnaud S, Paris F, Corre I. RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration. Biochem Biophys Res Commun 2011; 414:750-5; PMID:22001926; http://dx.doi.org/10.1016/j.bbrc.2011.09.150
-
(2011)
Biochem Biophys Res Commun
, vol.414
, pp. 750-755
-
-
Rousseau, M.1
Gaugler, M.H.2
Rodallec, A.3
Bonnaud, S.4
Paris, F.5
Corre, I.6
-
64
-
-
33744827683
-
Osmotic stress and the cytoskeleton: The R(h)ole of Rho GTPases
-
Oxf PMID:16734763
-
Di Ciano-Oliveira C, Thirone AC, Szászi K, Kapus A. Osmotic stress and the cytoskeleton: the R(h)ole of Rho GTPases. Acta Physiol (Oxf) 2006; 187:257-72; PMID:16734763; http://dx.doi.org/10.1111/j.1748-1716.2006.01535.x
-
(2006)
Acta Physiol
, vol.187
, pp. 257-272
-
-
Di Ciano-Oliveira, C.1
Thirone, A.C.2
Szászi, K.3
Kapus, A.4
-
65
-
-
23844488162
-
Regulation of cancer cell motility through actin reorganization
-
PMID:16053508
-
Yamazaki D, Kurisu S, Takenawa T. Regulation of cancer cell motility through actin reorganization. Cancer Sci 2005; 96:379-86; PMID:16053508; http://dx.doi.org/10.1111/j.1349-7006.2005.00062.x
-
(2005)
Cancer Sci
, vol.96
, pp. 379-386
-
-
Yamazaki, D.1
Kurisu, S.2
Takenawa, T.3
-
66
-
-
0038636056
-
RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia
-
PMID:12642488
-
Sepp KJ, Auld VJ. RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia. Development 2003; 130:1825-35; PMID:12642488; http://dx.doi.org/10.1242/dev.00413
-
(2003)
Development
, vol.130
, pp. 1825-1835
-
-
Sepp, K.J.1
Auld, V.J.2
-
67
-
-
0035158377
-
RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
-
PMID:11553710
-
Arthur WT, Burridge K. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol Biol Cell 2001; 12:2711-20; PMID:11553710.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 2711-2720
-
-
Arthur, W.T.1
Burridge, K.2
|