Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrier

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 36147-36157

  Kim, Jong Chul ^a   Crary, Benjamin ^a   Chang, Yun C ^b   Kwon Chung, Kyung J ^b   Kim, Kee J ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; CHEMICAL ACTIVATION; ELECTROPHORESIS; ENDOTHELIAL CELLS; ENZYMES; MONOLAYERS; PHOSPHORYLATION;

ACTIN CYTOSKELETON; BLOOD-BRAIN BARRIER; CRYPTOCOCCUS NEOFORMANS; DOMINANT NEGATIVE; FOCAL ADHESION KINASE; HUMAN BRAIN-MICROVASCULAR ENDOTHELIAL CELLS; MOLECULAR MECHANISM; WESTERN-BLOT ANALYSIS;

BLOOD;

ACTIN; EZRIN; FOCAL ADHESION KINASE; PROTEIN CDC42; PROTEIN KINASE C; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN FILAMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFECTION; CELL INVASION; CRYPTOCOCCUS NEOFORMANS; DOWN REGULATION; ENDOTHELIUM CELL; FUNGAL STRAIN; MENINGOENCEPHALITIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

EID: 84867760556     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.389676     Document Type: Article

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