A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 6979-6990

  Bouaouina, Mohamed ^a   Goult, Benjamin T ^b   Huet Calderwood, Clotilde ^a   Bate, Neil ^b   Brahme, Nina N ^a   Barsukov, Igor L ^c   Critchley, David R ^b   Calderwood, David A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADHERENT CELLS; ADHESION RECEPTORS; CO-ACTIVATION; CYTOPLASMIC DOMAINS; CYTOPLASMIC TAIL; FOCAL ADHESIONS; FUNCTIONAL SIMILARITY; HEAD GROUPS; INTEGRIN ACTIVATION; INTEGRINS; INTRACELLULAR SIGNALS; LIPID BINDING; LOW-TO-HIGH; MEMBRANE PHOSPHOLIPIDS; POLYLYSINE;

ADHESION; PHOSPHOLIPIDS;

CHEMICAL ACTIVATION;

ALPHA2BETA3 INTEGRIN; BETA INTEGRIN; BINDING PROTEIN; EZRIN; INTEGRIN; KINDLIN 1 PROTEIN; KINDLIN 2 PROTEIN; KINDLIN PROTEIN; LIPID BINDING PROTEIN; MEMBRANE PROTEIN; MOESIN; PHOSPHATIDYLSERINE; PHOSPHOLIPID; POLYLYSINE; RADIXIN; TALIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOPLASM VESICLE; FOCAL ADHESION; MEMBRANE BINDING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY;

AMINO ACID MOTIFS; ANIMALS; CARRIER PROTEINS; CELL ADHESION; CHO CELLS; CRICETINAE; CRICETULUS; CYTOSKELETAL PROTEINS; FOCAL ADHESIONS; HUMANS; MEMBRANE PROTEINS; MICE; MUSCLE PROTEINS; NEOPLASM PROTEINS; PHOSPHOLIPIDS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN STRUCTURE, TERTIARY; TALIN;

EID: 84857735762     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.330845     Document Type: Article

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