메뉴 건너뛰기




Volumn 125, Issue 4, 2012, Pages 844-857

N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration

Author keywords

Astrocyte; Cell migration; Cell polarity; Glioma; N cadherin

Indexed keywords

INTEGRIN; NERVE CELL ADHESION MOLECULE; PROTEIN CDC42;

EID: 84861213963     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.087668     Document Type: Article
Times cited : (117)

References (78)
  • 1
    • 34547651085 scopus 로고    scopus 로고
    • Differential cadherin expression: potential markers for epithelial to mesenchymal transformation during tumor progression
    • Agiostratidou, G., Hulit, J., Phillips, G. R. and Hazan, R. B. (2007). Differential cadherin expression: potential markers for epithelial to mesenchymal transformation during tumor progression. J. Mammary Gland Biol. Neoplasia 12, 127-133.
    • (2007) J. Mammary Gland Biol. Neoplasia , vol.12 , pp. 127-133
    • Agiostratidou, G.1    Hulit, J.2    Phillips, G.R.3    Hazan, R.B.4
  • 2
    • 77949453545 scopus 로고    scopus 로고
    • Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines
    • Amoureux, M. C., Coulibaly, B., Chinot, O., Loundou, A., Metellus, P., Rougon, G. and Figarella-Branger, D. (2010). Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines. BMC Cancer 10,91.
    • (2010) BMC Cancer , vol.10 , pp. 91
    • Amoureux, M.C.1    Coulibaly, B.2    Chinot, O.3    Loundou, A.4    Metellus, P.5    Rougon, G.6    Figarella-Branger, D.7
  • 4
    • 0035077317 scopus 로고    scopus 로고
    • The cadherin superfamily: diversity in form and function
    • Angst, B. D., Marcozzi, C. and Magee, A. I. (2001). The cadherin superfamily: diversity in form and function. J. Cell Sci. 114, 629-641.
    • (2001) J. Cell Sci. , vol.114 , pp. 629-641
    • Angst, B.D.1    Marcozzi, C.2    Magee, A.I.3
  • 6
    • 0034015414 scopus 로고    scopus 로고
    • Expression of cadherin and CSF dissemination in malignant astrocytic tumors
    • Asano, K., Kubo, O., Tajika, Y., Takakura, K. and Suzuki, S. (2000). Expression of cadherin and CSF dissemination in malignant astrocytic tumors. Neurosurg. Rev. 23, 39-44.
    • (2000) Neurosurg. Rev. , vol.23 , pp. 39-44
    • Asano, K.1    Kubo, O.2    Tajika, Y.3    Takakura, K.4    Suzuki, S.5
  • 8
    • 77955783595 scopus 로고    scopus 로고
    • Regulation of cell motile behavior by crosstalk between cadherin-and integrin-mediated adhesions
    • Borghi, N., Lowndes, M., Maruthamuthu, V., Gardel, M. L. and Nelson, W. J. (2010). Regulation of cell motile behavior by crosstalk between cadherin-and integrin-mediated adhesions. Proc. Natl. Acad. Sci. USA 107, 13324-13329.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 13324-13329
    • Borghi, N.1    Lowndes, M.2    Maruthamuthu, V.3    Gardel, M.L.4    Nelson, W.J.5
  • 9
    • 21644460380 scopus 로고    scopus 로고
    • Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways
    • Cau, J. and Hall, A. (2005). Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways. J. Cell Sci. 118, 2579-2587.
    • (2005) J. Cell Sci. , vol.118 , pp. 2579-2587
    • Cau, J.1    Hall, A.2
  • 10
    • 66349108868 scopus 로고    scopus 로고
    • Cell polarity triggered by cell-cell adhesion via E-cadherin
    • Desai, R. A., Gao, L., Raghavan, S., Liu, W. F. and Chen, C. S. (2009). Cell polarity triggered by cell-cell adhesion via E-cadherin. J. Cell Sci. 122, 905-911.
    • (2009) J. Cell Sci. , vol.122 , pp. 905-911
    • Desai, R.A.1    Gao, L.2    Raghavan, S.3    Liu, W.F.4    Chen, C.S.5
  • 11
    • 79954437964 scopus 로고    scopus 로고
    • Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases
    • Duenisch, P., Reichart, R., Mueller, U., Brodhun, M., Bjerkvig, R., Romeike, B., Walter, J., Herbold, C., Regenbrecht, C. R., Kalff, R. et al. (2010). Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases. J. Cancer Res. Clin. Oncol. 137, 399-414.
    • (2010) J. Cancer Res. Clin. Oncol. , vol.137 , pp. 399-414
    • Duenisch, P.1    Reichart, R.2    Mueller, U.3    Brodhun, M.4    Bjerkvig, R.5    Romeike, B.6    Walter, J.7    Herbold, C.8    Regenbrecht, C.R.9    Kalff, R.10
  • 12
    • 66349121353 scopus 로고    scopus 로고
    • Classical cadherins control nucleus and centrosome position and cell polarity
    • Dupin, I., Camand, E. and Etienne-Manneville, S. (2009). Classical cadherins control nucleus and centrosome position and cell polarity. J. Cell Biol. 185, 779-786.
    • (2009) J. Cell Biol. , vol.185 , pp. 779-786
    • Dupin, I.1    Camand, E.2    Etienne-Manneville, S.3
  • 13
    • 0028360081 scopus 로고
    • Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma-cell invasion and growth in vivo
    • Edvardsen, K., Pedersen, P. H., Bjerkvig, R., Hermann, G. G., Zeuthen, J., Laerum, O. D., Walsh, F. S. and Bock, E. (1994). Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma-cell invasion and growth in vivo. Int. J. Cancer 58, 116-122.
    • (1994) Int. J. Cancer , vol.58 , pp. 116-122
    • Edvardsen, K.1    Pedersen, P.H.2    Bjerkvig, R.3    Hermann, G.G.4    Zeuthen, J.5    Laerum, O.D.6    Walsh, F.S.7    Bock, E.8
  • 14
    • 2342432240 scopus 로고    scopus 로고
    • Cdc42 - the centre of polarity
    • Etienne-Manneville, S. (2004). Cdc42 - the centre of polarity. J. Cell Sci. 117, 1291-1300.
    • (2004) J. Cell Sci. , vol.117 , pp. 1291-1300
    • Etienne-Manneville, S.1
  • 15
    • 32144442590 scopus 로고    scopus 로고
    • In vitro assay of primary astrocyte migration as a tool to study Rho GTPase function in cell polarization
    • Etienne-Manneville, S. (2006). In vitro assay of primary astrocyte migration as a tool to study Rho GTPase function in cell polarization. Methods Enzymol. 406, 565-578.
    • (2006) Methods Enzymol , vol.406 , pp. 565-578
    • Etienne-Manneville, S.1
  • 16
    • 0035943401 scopus 로고    scopus 로고
    • Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta
    • Etienne-Manneville, S. and Hall, A. (2001). Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106, 489-498.
    • (2001) Cell , vol.106 , pp. 489-498
    • Etienne-Manneville, S.1    Hall, A.2
  • 17
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville, S. and Hall, A. (2003). Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature 421, 753-756.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 18
    • 24944577909 scopus 로고    scopus 로고
    • Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization
    • Etienne-Manneville, S., Manneville, J. B., Nicholls, S., Ferenczi, M. A. and Hall, A. (2005). Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization. J. Cell Biol. 170, 895-901.
    • (2005) J. Cell Biol. , vol.170 , pp. 895-901
    • Etienne-Manneville, S.1    Manneville, J.B.2    Nicholls, S.3    Ferenczi, M.A.4    Hall, A.5
  • 19
    • 0030052667 scopus 로고    scopus 로고
    • Involvement of wound-associated factors in rat brain astrocyte migratory response to axonal injury: in vitro simulation
    • Faber-Elman, A., Solomon, A., Abraham, J. A., Marikovsky, M. and Schwartz, M. (1996). Involvement of wound-associated factors in rat brain astrocyte migratory response to axonal injury: in vitro simulation. J. Clin. Invest. 97, 162-171.
    • (1996) J. Clin. Invest. , vol.97 , pp. 162-171
    • Faber-Elman, A.1    Solomon, A.2    Abraham, J.A.3    Marikovsky, M.4    Schwartz, M.5
  • 20
    • 4644343782 scopus 로고    scopus 로고
    • Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix
    • Feng, Q., Baird, D. and Cerione, R. A. (2004). Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix. EMBO J. 23, 3492-3504.
    • (2004) EMBO J , vol.23 , pp. 3492-3504
    • Feng, Q.1    Baird, D.2    Cerione, R.A.3
  • 21
    • 77953313163 scopus 로고    scopus 로고
    • Phosphorylation of the cool-1/beta-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells
    • Feng, Q., Baird, D., Yoo, S., Antonyak, M. and Cerione, R. A. (2010). Phosphorylation of the cool-1/beta-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells. J. Biol. Chem. 285, 18806-18816.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18806-18816
    • Feng, Q.1    Baird, D.2    Yoo, S.3    Antonyak, M.4    Cerione, R.A.5
  • 22
    • 5444244871 scopus 로고    scopus 로고
    • Cadherin-mediated cell-cell adhesion and tissue segregation in relation to malignancy
    • Foty, R. A. and Steinberg, M. S. (2004). Cadherin-mediated cell-cell adhesion and tissue segregation in relation to malignancy. Int. J. Dev. Biol. 48, 397-409.
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 397-409
    • Foty, R.A.1    Steinberg, M.S.2
  • 23
    • 0036467581 scopus 로고    scopus 로고
    • Advances in Rho-dependent actin regulation and oncogenic transformation
    • Frame, M. C. and Brunton, V. G. (2002). Advances in Rho-dependent actin regulation and oncogenic transformation. Curr. Opin. Genet. Dev. 12, 36-43.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 36-43
    • Frame, M.C.1    Brunton, V.G.2
  • 24
    • 41549102357 scopus 로고    scopus 로고
    • The PIX-GIT complex: a G protein signaling cassette in control of cell shape
    • Frank, S. R. and Hansen, S. H. (2008). The PIX-GIT complex: a G protein signaling cassette in control of cell shape. Semin. Cell Dev. Biol. 19, 234-244.
    • (2008) Semin. Cell Dev. Biol. , vol.19 , pp. 234-244
    • Frank, S.R.1    Hansen, S.H.2
  • 25
    • 1542682591 scopus 로고    scopus 로고
    • Glioma invasion - pattern of dissemination by mechanisms of invasion and surgical intervention, pattern of gene expression and its regulatory control by tumorsuppressor p53 and proto-oncogene ETS-1
    • Giese, A. (2003). Glioma invasion - pattern of dissemination by mechanisms of invasion and surgical intervention, pattern of gene expression and its regulatory control by tumorsuppressor p53 and proto-oncogene ETS-1. Acta Neurochir. Suppl. 88, 153-162.
    • (2003) Acta Neurochir. Suppl. , vol.88 , pp. 153-162
    • Giese, A.1
  • 26
    • 0033552615 scopus 로고    scopus 로고
    • Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function
    • Gimond, C., van Der Flier, A., van Delft, S., Brakebusch, C., Kuikman, I., Collard, J. G., Fassler, R. and Sonnenberg, A. (1999). Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function. J. Cell Biol. 147, 1325-1340.
    • (1999) J. Cell Biol. , vol.147 , pp. 1325-1340
    • Gimond, C.1    van Der Flier, A.2    van Delft, S.3    Brakebusch, C.4    Kuikman, I.5    Collard, J.G.6    Fassler, R.7    Sonnenberg, A.8
  • 27
    • 0031472674 scopus 로고    scopus 로고
    • Correlation of expression of NCAM and GD3 ganglioside to motile behaviour in neoplastic glia
    • Gratsa, A., Rooprai, H. K., Rogers, J. P., Martin, K. K. and Pilkington, G. J. (1997). Correlation of expression of NCAM and GD3 ganglioside to motile behaviour in neoplastic glia. Anticancer Res. 17, 4111-4117.
    • (1997) Anticancer Res , vol.17 , pp. 4111-4117
    • Gratsa, A.1    Rooprai, H.K.2    Rogers, J.P.3    Martin, K.K.4    Pilkington, G.J.5
  • 28
    • 75749103348 scopus 로고    scopus 로고
    • Src signaling in cancer invasion
    • Guarino, M. (2010). Src signaling in cancer invasion. J. Cell Physiol. 223, 14-26.
    • (2010) J. Cell Physiol. , vol.223 , pp. 14-26
    • Guarino, M.1
  • 29
    • 35648943165 scopus 로고    scopus 로고
    • mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration
    • Gupton, S. L., Eisenmann, K., Alberts, A. S. and Waterman-Storer, C. M. (2007). mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration. J. Cell Sci. 120, 3475-3487.
    • (2007) J. Cell Sci. , vol.120 , pp. 3475-3487
    • Gupton, S.L.1    Eisenmann, K.2    Alberts, A.S.3    Waterman-Storer, C.M.4
  • 30
    • 27844604200 scopus 로고    scopus 로고
    • Rho GTPases and the control of cell behaviour
    • Hall, A. (2005). Rho GTPases and the control of cell behaviour. Biochem. Soc. Trans. 33, 891-895.
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 891-895
    • Hall, A.1
  • 31
    • 0022621979 scopus 로고
    • Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development
    • Hatta, K. and Takeichi, M. (1986). Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 320, 447-449.
    • (1986) Nature , vol.320 , pp. 447-449
    • Hatta, K.1    Takeichi, M.2
  • 33
    • 33749425398 scopus 로고    scopus 로고
    • The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors
    • Hegedus, B., Marga, F., Jakab, K., Sharpe-Timms, K. L. and Forgacs, G. (2006). The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors. Biophys. J. 91, 2708-2716.
    • (2006) Biophys. J. , vol.91 , pp. 2708-2716
    • Hegedus, B.1    Marga, F.2    Jakab, K.3    Sharpe-Timms, K.L.4    Forgacs, G.5
  • 34
    • 0038795589 scopus 로고    scopus 로고
    • Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
    • Humbert, P., Russell, S. and Richardson, H. (2003). Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. BioEssays 25, 542-553.
    • (2003) BioEssays , vol.25 , pp. 542-553
    • Humbert, P.1    Russell, S.2    Richardson, H.3
  • 36
    • 54549104845 scopus 로고    scopus 로고
    • Crosstalk between small GTPases and polarity proteins in cell polarization
    • Iden, S. and Collard, J. G. (2008). Crosstalk between small GTPases and polarity proteins in cell polarization. Nat. Rev. Mol. Cell Biol. 9, 846-859.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 846-859
    • Iden, S.1    Collard, J.G.2
  • 37
    • 0032487494 scopus 로고    scopus 로고
    • An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    • Izumi, Y., Hirose, T., Tamai, Y., Hirai, S., Nagashima, Y., Fujimoto, T., Tabuse, Y., Kemphues, K. J. and Ohno, S. (1998). An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J. Cell Biol. 143, 95-106.
    • (1998) J. Cell Biol. , vol.143 , pp. 95-106
    • Izumi, Y.1    Hirose, T.2    Tamai, Y.3    Hirai, S.4    Nagashima, Y.5    Fujimoto, T.6    Tabuse, Y.7    Kemphues, K.J.8    Ohno, S.9
  • 39
    • 4043052971 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: twist in development and metastasis
    • Kang, Y. and Massague, J. (2004). Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 118, 277-279.
    • (2004) Cell , vol.118 , pp. 277-279
    • Kang, Y.1    Massague, J.2
  • 40
    • 0027301923 scopus 로고
    • The new WHO classification of brain tumours
    • Kleihues, P., Burger, P. C. and Scheithauer, B. W. (1993). The new WHO classification of brain tumours. Brain Pathol. 3, 255-268.
    • (1993) Brain Pathol , vol.3 , pp. 255-268
    • Kleihues, P.1    Burger, P.C.2    Scheithauer, B.W.3
  • 41
    • 65549120390 scopus 로고    scopus 로고
    • ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration
    • Kohutek, Z. A., diPierro, C. G., Redpath, G. T. and Hussaini, I. M. (2009). ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration. J. Neurosci. 29, 4605-4615.
    • (2009) J. Neurosci. , vol.29 , pp. 4605-4615
    • Kohutek, Z.A.1    diPierro, C.G.2    Redpath, G.T.3    Hussaini, I.M.4
  • 42
    • 30544454763 scopus 로고    scopus 로고
    • Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma
    • Kuphal, S. and Bosserhoff, A. K. (2006). Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma. Oncogene 25, 248-259.
    • (2006) Oncogene , vol.25 , pp. 248-259
    • Kuphal, S.1    Bosserhoff, A.K.2
  • 45
    • 16844379257 scopus 로고    scopus 로고
    • Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition
    • Maeda, M., Johnson, K. R. and Wheelock, M. J. (2005). Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition. J. Cell Sci. 118, 873-887.
    • (2005) J. Cell Sci. , vol.118 , pp. 873-887
    • Maeda, M.1    Johnson, K.R.2    Wheelock, M.J.3
  • 46
    • 0031008673 scopus 로고    scopus 로고
    • An inverse correlation between expression of NCAM-A and the matrix-metalloprotei-nases gelatinase-A and gelatinase-B in human glioma cells in vitro
    • Maidment, S. L., Rucklidge, G. J., Rooprai, H. K. and Pilkington, G. J. (1997). An inverse correlation between expression of NCAM-A and the matrix-metalloprotei-nases gelatinase-A and gelatinase-B in human glioma cells in vitro. Cancer Lett. 116, 71-77.
    • (1997) Cancer Lett , vol.116 , pp. 71-77
    • Maidment, S.L.1    Rucklidge, G.J.2    Rooprai, H.K.3    Pilkington, G.J.4
  • 47
    • 70450218151 scopus 로고    scopus 로고
    • Cell adhesion molecules: role and clinical significance in cancer
    • Makrilia, N., Kollias, A., Manolopoulos, L. and Syrigos, K. (2009). Cell adhesion molecules: role and clinical significance in cancer. Cancer Invest. 27, 1023-1037.
    • (2009) Cancer Invest , vol.27 , pp. 1023-1037
    • Makrilia, N.1    Kollias, A.2    Manolopoulos, L.3    Syrigos, K.4
  • 48
    • 0036731483 scopus 로고    scopus 로고
    • Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells
    • Manabe, N., Hirai, S., Imai, F., Nakanishi, H., Takai, Y. and Ohno, S. (2002). Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Dev. Dyn. 225, 61-69.
    • (2002) Dev. Dyn. , vol.225 , pp. 61-69
    • Manabe, N.1    Hirai, S.2    Imai, F.3    Nakanishi, H.4    Takai, Y.5    Ohno, S.6
  • 49
    • 0036156548 scopus 로고    scopus 로고
    • Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism
    • Mary, S., Charrasse, S., Meriane, M., Comunale, F., Travo, P., Blangy, A. and Gauthier-Rouviere, C. (2002). Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism. Mol. Biol. Cell 13, 285-301.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 285-301
    • Mary, S.1    Charrasse, S.2    Meriane, M.3    Comunale, F.4    Travo, P.5    Blangy, A.6    Gauthier-Rouviere, C.7
  • 51
    • 77954860342 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression
    • Micalizzi, D. S., Farabaugh, S. M. and Ford, H. L. (2010). Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression. J. Mammary Gland Biol. Neoplasia 15, 117-134.
    • (2010) J. Mammary Gland Biol. Neoplasia , vol.15 , pp. 117-134
    • Micalizzi, D.S.1    Farabaugh, S.M.2    Ford, H.L.3
  • 52
    • 0035825193 scopus 로고    scopus 로고
    • Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding
    • Michaelson, D., Silletti, J., Murphy, G., D'Eustachio, P., Rush, M. and Philips, M. R. (2001). Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding. J. Cell Biol. 152, 111-126.
    • (2001) J. Cell Biol. , vol.152 , pp. 111-126
    • Michaelson, D.1    Silletti, J.2    Murphy, G.3    D'Eustachio, P.4    Rush, M.5    Philips, M.R.6
  • 55
    • 0033594123 scopus 로고    scopus 로고
    • Rho GTPases control polarity, protrusion, and adhesion during cell movement
    • Nobes, C. D. and Hall, A. (1999). Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144, 1235-1244.
    • (1999) J. Cell Biol. , vol.144 , pp. 1235-1244
    • Nobes, C.D.1    Hall, A.2
  • 56
    • 33845472291 scopus 로고    scopus 로고
    • Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration
    • Osmani, N., Vitale, N., Borg, J. P. and Etienne-Manneville, S. (2006). Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration. Curr. Biol. 16, 2395-2405.
    • (2006) Curr. Biol. , vol.16 , pp. 2395-2405
    • Osmani, N.1    Vitale, N.2    Borg, J.P.3    Etienne-Manneville, S.4
  • 57
    • 78650719288 scopus 로고    scopus 로고
    • Cdc42 localization and cell polarity depend on membrane traffic
    • Osmani, N., Peglion, F., Chavrier, P. and Etienne-Manneville, S. (2010). Cdc42 localization and cell polarity depend on membrane traffic. J. Cell Biol. 191, 1261-1269.
    • (2010) J. Cell Biol. , vol.191 , pp. 1261-1269
    • Osmani, N.1    Peglion, F.2    Chavrier, P.3    Etienne-Manneville, S.4
  • 58
    • 0032080661 scopus 로고    scopus 로고
    • Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma
    • Owens, G. C., Orr, E. A., DeMasters, B. K., Muschel, R. J., Berens, M. E. and Kruse, C. A. (1998). Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma. Cancer Res. 58, 2020-2028.
    • (1998) Cancer Res , vol.58 , pp. 2020-2028
    • Owens, G.C.1    Orr, E.A.2    DeMasters, B.K.3    Muschel, R.J.4    Berens, M.E.5    Kruse, C.A.6
  • 59
    • 41549143107 scopus 로고    scopus 로고
    • Integrins and dystroglycan regulate astrocyte wound healing: the integrin beta1 subunit is necessary for process extension and orienting the microtubular network
    • Peng, H., Shah, W., Holland, P. and Carbonetto, S. (2008). Integrins and dystroglycan regulate astrocyte wound healing: the integrin beta1 subunit is necessary for process extension and orienting the microtubular network. Dev. Neurobiol. 68, 559-574.
    • (2008) Dev. Neurobiol. , vol.68 , pp. 559-574
    • Peng, H.1    Shah, W.2    Holland, P.3    Carbonetto, S.4
  • 60
    • 21044452876 scopus 로고    scopus 로고
    • The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue
    • Pera, I. L., Iuliano, R., Florio, T., Susini, C., Trapasso, F., Santoro, M., Chiariotti, L., Schettini, G., Viglietto, G. and Fusco, A. (2005). The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue. Oncogene 24, 3187-3195.
    • (2005) Oncogene , vol.24 , pp. 3187-3195
    • Pera, I.L.1    Iuliano, R.2    Florio, T.3    Susini, C.4    Trapasso, F.5    Santoro, M.6    Chiariotti, L.7    Schettini, G.8    Viglietto, G.9    Fusco, A.10
  • 61
    • 0037101955 scopus 로고    scopus 로고
    • Invasive behaviour of glioblastoma cell lines is associated with altered organisation of the cadherin-catenin adhesion system
    • Perego, C., Vanoni, C., Massari, S., Raimondi, A., Pola, S., Cattaneo, M. G., Francolini, M., Vicentini, L. M. and Pietrini, G. (2002). Invasive behaviour of glioblastoma cell lines is associated with altered organisation of the cadherin-catenin adhesion system. J. Cell Sci. 115, 3331-3340.
    • (2002) J. Cell Sci. , vol.115 , pp. 3331-3340
    • Perego, C.1    Vanoni, C.2    Massari, S.3    Raimondi, A.4    Pola, S.5    Cattaneo, M.G.6    Francolini, M.7    Vicentini, L.M.8    Pietrini, G.9
  • 62
    • 0014364322 scopus 로고
    • Long term culture of normal and neoplastic human glia
    • Ponten, J. and Macintyre, E. H. (1968). Long term culture of normal and neoplastic human glia. Acta Pathol. Microbiol. Scand. 74, 465-486.
    • (1968) Acta Pathol. Microbiol. Scand. , vol.74 , pp. 465-486
    • Ponten, J.1    Macintyre, E.H.2
  • 64
    • 1242284600 scopus 로고    scopus 로고
    • Regulation of cell migration by the C2 domain of the tumor suppressor PTEN
    • Raftopoulou, M., Etienne-Manneville, S., Self, A., Nicholls, S. and Hall, A. (2004). Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science 303, 1179-1181.
    • (2004) Science , vol.303 , pp. 1179-1181
    • Raftopoulou, M.1    Etienne-Manneville, S.2    Self, A.3    Nicholls, S.4    Hall, A.5
  • 65
    • 59349097033 scopus 로고    scopus 로고
    • EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin
    • Rappl, A., Piontek, G. and Schlegel, J. (2008). EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin. J. Cell Sci. 121, 4089-4097.
    • (2008) J. Cell Sci. , vol.121 , pp. 4089-4097
    • Rappl, A.1    Piontek, G.2    Schlegel, J.3
  • 66
    • 4444317085 scopus 로고    scopus 로고
    • Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer
    • Reynolds, A. B. and Carnahan, R. H. (2004). Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer. Semin. Cell Dev. Biol. 15, 657-663.
    • (2004) Semin. Cell Dev. Biol. , vol.15 , pp. 657-663
    • Reynolds, A.B.1    Carnahan, R.H.2
  • 67
    • 50949116343 scopus 로고    scopus 로고
    • Homotypic and endothelial cell adhesions via N-cadherin determine polarity and regulate migration of vascular smooth muscle cells
    • Sabatini, P. J., Zhang, M., Silverman-Gavrila, R., Bendeck, M. P. and Langille, B. L. (2008). Homotypic and endothelial cell adhesions via N-cadherin determine polarity and regulate migration of vascular smooth muscle cells. Circ. Res. 103, 405-412.
    • (2008) Circ. Res. , vol.103 , pp. 405-412
    • Sabatini, P.J.1    Zhang, M.2    Silverman-Gavrila, R.3    Bendeck, M.P.4    Langille, B.L.5
  • 68
    • 42049119895 scopus 로고    scopus 로고
    • Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells
    • Shen, Y., Li, N., Wu, S., Zhou, Y., Shan, Y., Zhang, Q., Ding, C., Yuan, Q., Zhao, F., Zeng, R. et al. (2008). Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells. Dev. Cell 14, 342-353.
    • (2008) Dev. Cell , vol.14 , pp. 342-353
    • Shen, Y.1    Li, N.2    Wu, S.3    Zhou, Y.4    Shan, Y.5    Zhang, Q.6    Ding, C.7    Yuan, Q.8    Zhao, F.9    Zeng, R.10
  • 71
    • 0025325167 scopus 로고
    • Cadherins: a molecular family important in selective cell-cell adhesion
    • Takeichi, M. (1990). Cadherins: a molecular family important in selective cell-cell adhesion. Annu. Rev. Biochem. 59, 237-252.
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 237-252
    • Takeichi, M.1
  • 72
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery, J. P. (2002). Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2, 442-454.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 73
    • 0035990052 scopus 로고    scopus 로고
    • Relationship between the expression of E-, N-cadherins and beta-catenin and tumor grade in astrocytomas
    • Utsuki, S., Sato, Y., Oka, H., Tsuchiya, B., Suzuki, S. and Fujii, K. (2002). Relationship between the expression of E-, N-cadherins and beta-catenin and tumor grade in astrocytomas. J. Neurooncol. 57, 187-192.
    • (2002) J. Neurooncol. , vol.57 , pp. 187-192
    • Utsuki, S.1    Sato, Y.2    Oka, H.3    Tsuchiya, B.4    Suzuki, S.5    Fujii, K.6
  • 74
    • 44449178868 scopus 로고    scopus 로고
    • Rho GTPases in cancer cell biology
    • Vega, F. M. and Ridley, A. J. (2008). Rho GTPases in cancer cell biology. FEBS Lett. 582, 2093-3101.
    • (2008) FEBS Lett , vol.582 , pp. 2093-3101
    • Vega, F.M.1    Ridley, A.J.2
  • 75
    • 36348970138 scopus 로고    scopus 로고
    • Dynamic interaction between Src and C-terminal Src kinase in integrin alphaIIbbeta3-mediated signaling to the cytoskeleton
    • Vielreicher, M., Harms, G., Butt, E., Walter, U. and Obergfell, A. (2007). Dynamic interaction between Src and C-terminal Src kinase in integrin alphaIIbbeta3-mediated signaling to the cytoskeleton. J. Biol. Chem. 282, 33623-33631.
    • (2007) J. Biol. Chem. , vol.282 , pp. 33623-33631
    • Vielreicher, M.1    Harms, G.2    Butt, E.3    Walter, U.4    Obergfell, A.5
  • 76
    • 13244269913 scopus 로고    scopus 로고
    • Regulation of microtubules in cell migration
    • Watanabe, T., Noritake, J. and Kaibuchi, K. (2005). Regulation of microtubules in cell migration. Trends Cell Biol. 15, 76-83.
    • (2005) Trends Cell Biol , vol.15 , pp. 76-83
    • Watanabe, T.1    Noritake, J.2    Kaibuchi, K.3
  • 78
    • 3342896372 scopus 로고    scopus 로고
    • Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion
    • Yano, H., Mazaki, Y., Kurokawa, K., Hanks, S. K., Matsuda, M. and Sabe, H. (2004). Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion. J. Cell Biol. 166, 283-295.
    • (2004) J. Cell Biol. , vol.166 , pp. 283-295
    • Yano, H.1    Mazaki, Y.2    Kurokawa, K.3    Hanks, S.K.4    Matsuda, M.5    Sabe, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.