The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

Oncogene

Volumn 31, Issue 1, 2012, Pages 68-79

  Badgwell, D B ^a   Lu, Z ^a   Le, K ^a   Gao, F ^a   Yang, M ^a   Suh, G K ^a   Bao, J J ^a   Das, P ^a   Andreeff, M ^a   Chen, W ^a   Yu, Y ^a   Ahmed, A A ^a   S L Liao, W ^a   Bast Jr , R C ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

cytoskeleton; migration suppression; RhoA GTPase; Stat3; tumor suppressor gene ARHI

Indexed keywords

FOCAL ADHESION KINASE; PROTEIN ARHI; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STAT3 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARHI GENE; ARTICLE; CANCER CELL CULTURE; GENE FUNCTION; OVARY CANCER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STRESS FIBER; TUMOR SUPPRESSOR GENE;

CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; GENES, TUMOR SUPPRESSOR; HUMANS; JANUS KINASE 2; OVARIAN NEOPLASMS; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84855355011     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.213     Document Type: Article

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